Journal of Clinical Sleep Medicine最新文献

{"title":"Effort/reward imbalance and comorbidities burden in academic and professional careers of patients with narcolepsy type 1.","authors":"Laure Peter-Derex, Emmanuel Fort, Benjamin Putois, Nora Martel, François Ricordeau, Hélène Bastuji, Isabelle Arnulf, Lucie Barateau, Patrice Bourgin, Yves Dauvilliers, Rachel Debs, Pauline Dodet, Benjamin Dudoignon, Patricia Franco, Sarah Hartley, Isabelle Lambert, Michel Lecendreux, Laurene Leclair-Visonneau, Damien Léger, Martine Lemesle-Martin, Antoine Léotard, Smaranda Leu-Semenescu, Nadège Limousin, Régis Lopez, Nicole Meslier, Jean-Arthur Micoulaud-Franchi, Christelle Charley-Mocana, Marie-Pia d'Ortho, Pierre Philip, Elisabeth Ruppert, Sylvie de La Tullaye, Manon Brigandet, Jennnifer Margier, Benjamin Rolland, Barbara Charbotel, Stéphanie Mazza","doi":"10.5664/jcsm.11598","DOIUrl":"https://doi.org/10.5664/jcsm.11598","url":null,"abstract":"<p><strong>Study objectives: </strong>This multi-center comparative cross-sectional study aimed to describe educational and occupational pathways, quantify effort/reward imbalance at work and identify factors associated with professional prognosis in patients with narcolepsy type 1 (NT1).</p><p><strong>Methods: </strong>Adult patients with NT1 and controls answered online questionnaires (Epworth sleepiness Scale, Beck Depression Inventory II, Siegrist questionnaire, Adult Self-Report, and a questionnaire on academic and professional trajectories) and were compared using sex- and age-adjusted logistic regressions. Clinical, demographic and psycho-social factors associated with patients' professional prognosis, as assessed by a composite score based on occupational-related outcomes, were explored with a generalized linear model.</p><p><strong>Results: </strong>We included 235 patients (63.8% women, 36.4±14.7 years, 86.5% treated, 66.4% with childhood onset) and 166 controls (69.9% women, 40.3±14.4 years). No difference was observed between patients and controls for graduation, but patients reported more interruptions, absenteeism and lateness during schooling. No difference was observed for employment rate (69.5% vs 77.0%), but income was lower in patients who reported more unwanted changes in position and part-time work, with increased effort-reward imbalance (OR=2.28 95%CI[1.20-4.33], p=0.01). Impaired professional prognosis was associated with depression (p<0.0001) and attention disorders (p=0.03), while being narcoleptic during schooling was a protective factor (p=0.02).</p><p><strong>Conclusions: </strong>Most patients with NT1 manage to achieve their careers goals, but at the cost of an effort/reward imbalance. Early diagnosis might allow a better adjustment to the disease. The strong impact of psycho-cognitive comorbidities on professional outcomes stresses the need to consider psycho-cognitivo-social dimensions in patient care.</p><p><strong>Clinical trial registration: </strong>Registry: ClinicalTrials.gov; Identifier: NCT03765892.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring hypoglossal nerve stimulator outcomes.","authors":"Eric J Kezirian","doi":"10.5664/jcsm.11608","DOIUrl":"https://doi.org/10.5664/jcsm.11608","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polysomnography phenotype of CANVAS with Parkinsonism.","authors":"Veronica Ricci, Emilien Delmont, Stephan Grimaldi, Alexandre Eusebio, Isabelle Lambert","doi":"10.5664/jcsm.11586","DOIUrl":"https://doi.org/10.5664/jcsm.11586","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing the robustness and clarity of future Mendelian randomization studies in sleep medicine.","authors":"Xuejiao Zhang, Yujing Sun, Guohua Li, Sizhi Ai","doi":"10.5664/jcsm.11602","DOIUrl":"https://doi.org/10.5664/jcsm.11602","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Confirmatory evidence for circadian rhythm sleep-wake disorder by positive airway pressure therapy adherence data.","authors":"Hussam Jenad, Erik K St Louis, R Robert Auger","doi":"10.5664/jcsm.11572","DOIUrl":"https://doi.org/10.5664/jcsm.11572","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis and management of Cheyne-Stokes respiration as a complication of dilated cardiomyopathy in a 10-year-old child.","authors":"Laura E Hill, Lorna Blackmore, Manjith Narayanan, Emma Carruthers, Richard Ferguson, Florian Gahleitner, Donald S Urquhart","doi":"10.5664/jcsm.11568","DOIUrl":"https://doi.org/10.5664/jcsm.11568","url":null,"abstract":"<p><p>Central sleep apnea due to Cheyne-Stokes respiration (CSA-CSR) is frequently described in adults with cardiac failure, but few (<20) cases are reported in children. We report the case of a 10-year old boy with dilated cardiomyopathy and cardiac failure (left ventricular ejection fraction 36%), in whom recurrent, prolonged pauses in breathing during sleep were noted. A cardiorespiratory polygraphy (CRpoly) sleep study was performed, which demonstrated the presence of CSA-CSR. 373 central events were scored and central apnea-hypopnea index (cAHI) was 47.4. Overnight continuous positive airways pressure (CPAP) was commenced via a nasal mask. Both child and mother reported improved well-being on CPAP, and a repeat CRpoly on CPAP noted a fall in cAHI to 1.2. We believe this to be the first case describing successful treatment of CSA-CSR in a child using CPAP. The improvement in patient well-being highlights the importance of a sleep history and/or sleep studies in children with cardiac failure.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mean disease alleviation as a comprehensive metric for evaluating continuous positive airway pressure therapy in obstructive sleep apnea: establishing reference values and clinical significance.","authors":"Rohit Budhiraja, Salma Batool-Anwar, Stuart F Quan","doi":"10.5664/jcsm.11592","DOIUrl":"https://doi.org/10.5664/jcsm.11592","url":null,"abstract":"<p><strong>Study objectives: </strong>Obstructive sleep apnea (OSA) poses significant health risks, warranting effective treatment strategies. While Continuous Positive Airway Pressure (CPAP) therapy is widely utilized, assessing treatment effectiveness remains complex. This study aimed to establish reference values for mean disease alleviation (MDA) in a large CPAP-treated cohort.</p><p><strong>Methods: </strong>Data from the Apnea Positive Pressure Long-term Efficacy Study (APPLES) were analyzed. A total of 352 participants underwent 6 months of CPAP therapy, with adherence and efficacy monitored objectively. MDA, calculated as the product of treatment efficacy and percentage adherence, was assessed. Age and sex differences in MDA and its association with sleepiness (Epworth Sleepiness Scale scores >10) were evaluated using logistic regression and linear regression models.</p><p><strong>Results: </strong>The mean MDA in the 352 participants at 6 months was 61.1% (±34.2%), with a significant positive correlation between MDA and adherence (R=0.81, P<0.001). Older participants demonstrated higher adherence and MDA compared to younger participants (58.2% ± 27.8% vs. 51.1% ± 27.4%, P=0.047). Despite higher efficacy, females demonstrated lower adherence, yielding comparable MDA levels to males. Participants achieving MDA ≥40% had significantly lower odds of sleepiness (OR=0.40, 95% CI: 0.23-0.70, P=0.001).</p><p><strong>Conclusions: </strong>MDA serves as a valuable metric for evaluating OSA therapy outcomes, integrating both adherence and treatment efficacy. MDA ≥40% was associated with clinically meaningful improvements in sleepiness. Embracing MDA as a benchmark for OSA therapy evaluation holds promise for optimizing personalized and effective OSA management and improving patient outcomes. Future research should focus on optimizing MDA and exploring its impact on long-term outcomes.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The accuracy of WatchPAT in obese adolescents.","authors":"Giora Pillar","doi":"10.5664/jcsm.11590","DOIUrl":"https://doi.org/10.5664/jcsm.11590","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor concerning \"Effects of aerobic exercise and resistance training on obstructive sleep apnea: a systematic review and meta-analysis\" by Lin et al.","authors":"Joshua Holley, Brendon Yee, Elizabeth Machan","doi":"10.5664/jcsm.11596","DOIUrl":"https://doi.org/10.5664/jcsm.11596","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How adherent are children with Down syndrome and obstructive sleep apnea to positive airway pressure therapy?","authors":"Sanjeev V Kothare, Kristen Kelly-Pieper","doi":"10.5664/jcsm.11600","DOIUrl":"https://doi.org/10.5664/jcsm.11600","url":null,"abstract":"","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}