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Journal of Investigational Allergology and Clinical Immunology最新文献

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Concomitant Efficacy of Dupilumab in Treating Eosinophilic Esophagitis and Type 2 Asthma. 杜匹单抗治疗嗜酸性粒细胞食管炎和 2 型哮喘的并发疗效
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-12-03 Epub Date: 2024-05-10 DOI: 10.18176/jiaci.1011
M Tomás-Pérez, A Trisán Alonso, A Montoro-Ferrer, J Domínguez-Ortega, P A Galindo-Bonilla, M Clar Castelló, J E Naves, P Ausín
{"title":"Concomitant Efficacy of Dupilumab in Treating Eosinophilic Esophagitis and Type 2 Asthma.","authors":"M Tomás-Pérez, A Trisán Alonso, A Montoro-Ferrer, J Domínguez-Ortega, P A Galindo-Bonilla, M Clar Castelló, J E Naves, P Ausín","doi":"10.18176/jiaci.1011","DOIUrl":"10.18176/jiaci.1011","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"412-414"},"PeriodicalIF":6.1,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A 1-Bag/4-Step Rapid Desensitization Protocol to Reintroduce Agalsidase a in a Patient With Fabry Disease. 1袋/4步快速脱敏方案在法布里病患者中重新引入Agalsidase A
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-12-02 DOI: 10.18176/jiaci.1044
T W Jimenez-Rodriguez, V Soriano Gomis, A Burgos San-José, R A Montoyo Antón, M P González Delgado, C P Gallego Velez, S Ortolano, J Fernández, R Sánchez Martínez
{"title":"A 1-Bag/4-Step Rapid Desensitization Protocol to Reintroduce Agalsidase a in a Patient With Fabry Disease.","authors":"T W Jimenez-Rodriguez, V Soriano Gomis, A Burgos San-José, R A Montoyo Antón, M P González Delgado, C P Gallego Velez, S Ortolano, J Fernández, R Sánchez Martínez","doi":"10.18176/jiaci.1044","DOIUrl":"https://doi.org/10.18176/jiaci.1044","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"0"},"PeriodicalIF":6.1,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142773946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ATAK Complex Induced by Ranitidine: A Comprehensive Concept for Cardiac Involvement in Allergic Reactions. 雷尼替丁诱发的 ATAK 复合物：过敏反应中心脏参与的综合概念。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-11-28 DOI: 10.18176/jiaci.1042
A Lopez-Raigada, F Vega, M V Múgica, C Lopez-Sanz, A Alfranca, C Blanco
{"title":"ATAK Complex Induced by Ranitidine: A Comprehensive Concept for Cardiac Involvement in Allergic Reactions.","authors":"A Lopez-Raigada, F Vega, M V Múgica, C Lopez-Sanz, A Alfranca, C Blanco","doi":"10.18176/jiaci.1042","DOIUrl":"https://doi.org/10.18176/jiaci.1042","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"0"},"PeriodicalIF":6.1,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug-induced Kounis Syndrome: A Retrospective Pharmacovigilance Study from the FAERS and JADER Databases. 药物诱发的库尼斯综合征：来自 FAERS 和 JADER 数据库的回顾性药物警戒研究。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-11-28 DOI: 10.18176/jiaci.1039
H Li, Y Liu, L Tan, C Hu, L Su
{"title":"Drug-induced Kounis Syndrome: A Retrospective Pharmacovigilance Study from the FAERS and JADER Databases.","authors":"H Li, Y Liu, L Tan, C Hu, L Su","doi":"10.18176/jiaci.1039","DOIUrl":"https://doi.org/10.18176/jiaci.1039","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"0"},"PeriodicalIF":6.1,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Biologics in Patients With Severe Asthma and Psychiatric Comorbidities. 生物制剂对严重哮喘合并精神疾病患者的疗效。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-11-27 DOI: 10.18176/jiaci.1034
B Mascaró-Hereza, D Loli-Ausejo, A Valero, E Arismendi, I Bobolea
{"title":"Effectiveness of Biologics in Patients With Severe Asthma and Psychiatric Comorbidities.","authors":"B Mascaró-Hereza, D Loli-Ausejo, A Valero, E Arismendi, I Bobolea","doi":"10.18176/jiaci.1034","DOIUrl":"https://doi.org/10.18176/jiaci.1034","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"0"},"PeriodicalIF":6.1,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anaphylaxis Caused by a Mouse Bite in a Laboratory Researcher. 一名实验室研究人员被老鼠咬伤引发过敏性休克。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-11-25 DOI: 10.18176/jiaci.1040
S A Dager-García, A Germán-Sánchez, F Pineda de la Losa, A M Ferrer Franco
{"title":"Anaphylaxis Caused by a Mouse Bite in a Laboratory Researcher.","authors":"S A Dager-García, A Germán-Sánchez, F Pineda de la Losa, A M Ferrer Franco","doi":"10.18176/jiaci.1040","DOIUrl":"https://doi.org/10.18176/jiaci.1040","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"0"},"PeriodicalIF":6.1,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tezepelumab in Patients With Severe Asthma: Response at 3 Months. 特珠单抗治疗严重哮喘患者：3个月后的反应
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-11-25 DOI: 10.18176/jiaci.1041
J C Miralles-López, R Andújar-Espinosa, F J Bravo-Gutierrez, S Cabrejos-Perotti, M Ramírez-Hernández, C Díaz-Chantar, M J Pajarón-Fernández, J Valverde-Molina, V Pérez-Fernández
{"title":"Tezepelumab in Patients With Severe Asthma: Response at 3 Months.","authors":"J C Miralles-López, R Andújar-Espinosa, F J Bravo-Gutierrez, S Cabrejos-Perotti, M Ramírez-Hernández, C Díaz-Chantar, M J Pajarón-Fernández, J Valverde-Molina, V Pérez-Fernández","doi":"10.18176/jiaci.1041","DOIUrl":"https://doi.org/10.18176/jiaci.1041","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"0"},"PeriodicalIF":6.1,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fatal CAEBV-Associated Vasculitis in ICF Syndrome Type 2. ICF 综合征 2 型中致命的 CAEBV 相关性血管炎。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-11-25 DOI: 10.18176/jiaci.1037
T Shigemura, N Kobayashi, T Uehara, Y Nakazawa
{"title":"Fatal CAEBV-Associated Vasculitis in ICF Syndrome Type 2.","authors":"T Shigemura, N Kobayashi, T Uehara, Y Nakazawa","doi":"10.18176/jiaci.1037","DOIUrl":"https://doi.org/10.18176/jiaci.1037","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"0"},"PeriodicalIF":6.1,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occupational Asthma and Rhinoconjunctivitis due to Soybean in a Bakery Worker. 一名面包店工人因大豆引发职业性哮喘和鼻结膜炎。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-11-13 DOI: 10.18176/jiaci.1035
Ö Özdemir
{"title":"Occupational Asthma and Rhinoconjunctivitis due to Soybean in a Bakery Worker.","authors":"Ö Özdemir","doi":"10.18176/jiaci.1035","DOIUrl":"https://doi.org/10.18176/jiaci.1035","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"0"},"PeriodicalIF":6.1,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal Follow-up Reveals Peripheral Immunological Changes Upon Tick Bite in a-Gal-Sensitized Individuals. 疟原虫过敏者被蜱虫叮咬后外周免疫学变化的纵向随访揭示。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-11-13 DOI: 10.18176/jiaci.1028
K Swiontek, J Fischer, F Hedin, D Revets, S Riel, N Chakrapani, U Mackenstedt, T Biedermann, A Kuehn, A Cosma, M Ollert, C Hilger
{"title":"Longitudinal Follow-up Reveals Peripheral Immunological Changes Upon Tick Bite in a-Gal-Sensitized Individuals.","authors":"K Swiontek, J Fischer, F Hedin, D Revets, S Riel, N Chakrapani, U Mackenstedt, T Biedermann, A Kuehn, A Cosma, M Ollert, C Hilger","doi":"10.18176/jiaci.1028","DOIUrl":"10.18176/jiaci.1028","url":null,"abstract":"<p><strong>Background and objectives: </strong>α-Gal syndrome is characterized by specific IgE (sIgE) antibodies to the carbohydrate galactose-α-1,3-galactose (α-Gal) and delayed onset of allergic symptoms after ingestion of mammalian meat. While tick bites are assumed to mediate sensitization, the immune response to tick bites has not yet been investigated. To investigate the peripheral immune response to tick bites in humans over time.</p><p><strong>Methods: </strong>In a longitudinal cohort study, immunological reactions associated with tick bites (Ixodes species) were analyzed within 1 day (V1), 2 weeks (V2), 1 month (V3), and 3 months (V4) after the occurrence of a bite. sIgE, sIgG, and sIgG subclass levels, as well as 10 cytokines, were quantified. Deep immune phenotyping was performed using mass cytometry.</p><p><strong>Results: </strong>A total of 4 controls and 10 patients were bitten by a tick and followed up over 3 months. None of the controls developed sIgE to α-Gal, and sIgE increased in all patients from V1 until V2/V3, as did IL-8 levels. We noted a significant increase in CD19+ B cells and B-cell subpopulations, as well as a decrease in γδ CD56+ T cells in patients between V0 and V1. At V1, frequencies of plasmacytoid dendritic cells (pDCs) and γδ CD56+ T cells were lower in patients than in controls.</p><p><strong>Conclusion: </strong>Our study provides evidence of significant changes in several immune cell populations in α-Gal sensitized patients, along with increased levels of IL-8 and sIgE. This is the first exploratory study to investigate longitudinal peripheral immune profiles in patients and controls bitten by ticks.</p>","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"0"},"PeriodicalIF":6.1,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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