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Journal of Investigational Allergology and Clinical Immunology最新文献

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Protocol for Successful Desensitization to Ivacaftor and Elexacaftor/Tezacaftor/Ivacaftor in a Delayed Hypersensitivity Reaction Confirmed by the Lymphocyte Transformation Test. 经淋巴细胞转化试验证实，Ivacaftor及elexaftor /Tezacaftor/Ivacaftor复合物在迟发性超敏反应中的成功脱敏方案。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-06-17 Epub Date: 2023-11-15 DOI: 10.18176/jiaci.0961
P Mir-Ihara, L De Las Vecillas, R Heredia, A Fiandor, M González-Muñoz, E Zamarrón, C Prados, R Cabañas
{"title":"Protocol for Successful Desensitization to Ivacaftor and Elexacaftor/Tezacaftor/Ivacaftor in a Delayed Hypersensitivity Reaction Confirmed by the Lymphocyte Transformation Test.","authors":"P Mir-Ihara, L De Las Vecillas, R Heredia, A Fiandor, M González-Muñoz, E Zamarrón, C Prados, R Cabañas","doi":"10.18176/jiaci.0961","DOIUrl":"10.18176/jiaci.0961","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"211-213"},"PeriodicalIF":6.1,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107592724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anaphylactic Shock due to Isatuximab and Successful Desensitization. 依沙妥昔单抗引起的过敏性休克和成功脱敏。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-06-17 Epub Date: 2023-10-09 DOI: 10.18176/jiaci.0951
M C Torres Górriz, J Borrás Cuartero, A Germán Sánchez, C G Pesántez Méndez, C I Stein Coronado, M Fernández-Delgado, S Beltrán Agost, E Enrique
{"title":"Anaphylactic Shock due to Isatuximab and Successful Desensitization.","authors":"M C Torres Górriz, J Borrás Cuartero, A Germán Sánchez, C G Pesántez Méndez, C I Stein Coronado, M Fernández-Delgado, S Beltrán Agost, E Enrique","doi":"10.18176/jiaci.0951","DOIUrl":"10.18176/jiaci.0951","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"200-202"},"PeriodicalIF":6.1,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41174666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilastine 0.6% Preservative-free Eye Drops: A Once-daily Treatment for Allergic Conjunctivitis. 不含防腐剂的比拉斯汀 0.6% 滴眼液，每天一次，用于治疗过敏性结膜炎。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-06-17 Epub Date: 2023-02-23 DOI: 10.18176/jiaci.0894
P J Gomes, J B Ciolino, P Arranz, G Hernández, N Fernández
{"title":"Bilastine 0.6% Preservative-free Eye Drops: A Once-daily Treatment for Allergic Conjunctivitis.","authors":"P J Gomes, J B Ciolino, P Arranz, G Hernández, N Fernández","doi":"10.18176/jiaci.0894","DOIUrl":"10.18176/jiaci.0894","url":null,"abstract":"<p><strong>Background and objective: </strong>Bilastine is a second-generation antihistamine approved for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria. The present trial evaluated the efficacy and safety of a new bilastine 0.6% preservative-free eye drop formulation for the symptomatic treatment of allergic conjunctivitis.</p><p><strong>Methods: </strong>This phase 3, multicenter, double-masked, randomized study compared the efficacy, safety, and tolerability profile of bilastine 0.6% ophthalmic solution with that of ketotifen 0.025% and vehicle. The primary efficacy endpoint was reduction in ocular itching. The Ora-CAC® Allergen Challenge Model was used to assess ocular and nasal symptoms at 15 minutes (onset of action) and 16 hours after treatment.</p><p><strong>Results: </strong>Patients (N=228) were 59.6% male, and the mean (SD) age was 44.1 (13.4) years. Bilastine demonstrated efficacy in reducing ocular itching compared to vehicle at both onset of action and 16 hours after treatment (P<.001). Symptoms improved with ketotifen compared to vehicle 15 minutes after treatment (P<.001). Bilastine demonstrated statistical noninferiority to ketotifen for all 3 post-CAC timepoints at 15 minutes after instillation, based on an inferiority margin of 0.4. Compared with vehicle, bilastine improved in conjunctival redness, ciliary redness, episcleral redness, chemosis, eyelid swelling, tearing, rhinorrhea, ear and palate pruritus, and nasal congestion at 15 minutes after treatment (P<.05). Ophthalmic bilastine was safe and well tolerated. Mean drop comfort scores were significantly better for bilastine than for ketotifen immediately upon instillation (P<.05) and similar to those of vehicle.</p><p><strong>Conclusion: </strong>Ophthalmic bilastine effectively reduced ocular itching for 16 hours after administration, suggesting that it could be used as a once-daily treatment for the signs and symptoms of allergic conjunctivitis. ClinicalTrials.gov identifier: NCT03479307.</p>","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"167-176"},"PeriodicalIF":6.1,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9307309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subcutaneous C1 Inhibitor for Long-term Prophylaxis of Hereditary Angioedema: A Real-life Experience. 皮下C1抑制剂用于遗传性血管性水肿的长期预防-真实生活经验。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-06-17 Epub Date: 2023-09-05 DOI: 10.18176/jiaci.0948
K Baynova, S Cimbollek, J Quiralte, R García, J M Lucena, E Lasa Luaces, M A Lara Jiménez, J Alvarez Nieto, J Moreto, T González-Quevedo
{"title":"Subcutaneous C1 Inhibitor for Long-term Prophylaxis of Hereditary Angioedema: A Real-life Experience.","authors":"K Baynova, S Cimbollek, J Quiralte, R García, J M Lucena, E Lasa Luaces, M A Lara Jiménez, J Alvarez Nieto, J Moreto, T González-Quevedo","doi":"10.18176/jiaci.0948","DOIUrl":"10.18176/jiaci.0948","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"198-199"},"PeriodicalIF":6.1,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41135878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occupational Asthma and Food Allergy due to Soybean in a Bakery Worker. 一名烘焙工人因大豆引发的职业性哮喘和食物过敏。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-06-17 Epub Date: 2023-10-31 DOI: 10.18176/jiaci.0958
E Narváez-Fernández, K Pose, M L Caballero, R Rodríguez-Pérez, S Quirce
{"title":"Occupational Asthma and Food Allergy due to Soybean in a Bakery Worker.","authors":"E Narváez-Fernández, K Pose, M L Caballero, R Rodríguez-Pérez, S Quirce","doi":"10.18176/jiaci.0958","DOIUrl":"10.18176/jiaci.0958","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"207-209"},"PeriodicalIF":6.1,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71414991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply to: Successful Isatuximab Desensitization in a Patient With Refractory Multiple Myeloma and Indolent Systemic Mastocytosis. 回复：一位难治性多发性骨髓瘤和系统性乳腺增生症患者的伊沙妥昔单抗脱敏治疗获得成功。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-06-17 Epub Date: 2024-01-26 DOI: 10.18176/jiaci.0992
M C Torres Górriz, J Borrás Cuartero, C G Pesántez Méndez, C I Stein Coronado, E Enrique
{"title":"Reply to: Successful Isatuximab Desensitization in a Patient With Refractory Multiple Myeloma and Indolent Systemic Mastocytosis.","authors":"M C Torres Górriz, J Borrás Cuartero, C G Pesántez Méndez, C I Stein Coronado, E Enrique","doi":"10.18176/jiaci.0992","DOIUrl":"10.18176/jiaci.0992","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"216-217"},"PeriodicalIF":6.1,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139565274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strongyloidiasis in the Allergology Department of a Tertiary Hospital in Valencia Province (Spain): A Retrospective Study (2010-2023). 西班牙瓦伦西亚省某三级医院过敏症科的圆线虫病:一项回顾性研究(2010-2023)
IF 7.2 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-06-17 Epub Date: 2023-11-15 DOI: 10.18176/jiaci.0955
M D de Las Marinas Alvarez, C S Romero, R Felix Toledo, M Alvariño Martín, C Martorell Calatayud, J C Cerdá Mir, D Navalpotro Rodríguez, A Martorell Aragones
{"title":"Strongyloidiasis in the Allergology Department of a Tertiary Hospital in Valencia Province (Spain): A Retrospective Study (2010-2023).","authors":"M D de Las Marinas Alvarez, C S Romero, R Felix Toledo, M Alvariño Martín, C Martorell Calatayud, J C Cerdá Mir, D Navalpotro Rodríguez, A Martorell Aragones","doi":"10.18176/jiaci.0955","DOIUrl":"10.18176/jiaci.0955","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"188-190"},"PeriodicalIF":7.2,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107592723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid Clearance of Corticosteroid-Resistant Targetoid Acute Generalized Exanthematous Pustulosis Using an IL-17A Inhibitor: A Case Report. 应用IL-17A抑制剂快速清除皮质类固醇耐药靶向药物急性全身性水肿：一例报告。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-06-17 Epub Date: 2023-09-05 DOI: 10.18176/jiaci.0946
J Wen, Y Wang, B Wang, B Jiang, J Lan, J Yang, J Tao, C Shen, Y Li
{"title":"Rapid Clearance of Corticosteroid-Resistant Targetoid Acute Generalized Exanthematous Pustulosis Using an IL-17A Inhibitor: A Case Report.","authors":"J Wen, Y Wang, B Wang, B Jiang, J Lan, J Yang, J Tao, C Shen, Y Li","doi":"10.18176/jiaci.0946","DOIUrl":"10.18176/jiaci.0946","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"196-197"},"PeriodicalIF":6.1,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41118409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Mepolizumab for the Treatment of Eosinophilic Cystitis: A Report of 2 Cases. 美波珠单抗治疗嗜酸性膀胱炎的疗效：两例报告。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-06-17 Epub Date: 2023-10-18 DOI: 10.18176/jiaci.0954
L Trefond, L Guy, C Darcha, A Gallon, R Thomas-Monier, K Berdugo, P Smets, L Olagne, J Stievenart, D Fayard, P Cathebras, O Aumaitre, L Boyer, M Andre, J E Kahn
{"title":"Efficacy of Mepolizumab for the Treatment of Eosinophilic Cystitis: A Report of 2 Cases.","authors":"L Trefond, L Guy, C Darcha, A Gallon, R Thomas-Monier, K Berdugo, P Smets, L Olagne, J Stievenart, D Fayard, P Cathebras, O Aumaitre, L Boyer, M Andre, J E Kahn","doi":"10.18176/jiaci.0954","DOIUrl":"10.18176/jiaci.0954","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"202-204"},"PeriodicalIF":6.1,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41240459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sensorineural Hearing Loss Is an Unrecognized Complication of Common Variable Immunodeficiency. 感觉神经性听力损失（SNHL）是常见可变免疫缺陷（CVID）的一种未被认识的并发症。
IF 6.1 3区 医学
Journal of Investigational Allergology and Clinical Immunology Pub Date : 2024-06-17 Epub Date: 2023-10-31 DOI: 10.18176/jiaci.0956
G Tessarin, M Baronio, L Gazzurelli, S Rossi, A Caravaggio, R Badolato, V Lougaris
{"title":"Sensorineural Hearing Loss Is an Unrecognized Complication of Common Variable Immunodeficiency.","authors":"G Tessarin, M Baronio, L Gazzurelli, S Rossi, A Caravaggio, R Badolato, V Lougaris","doi":"10.18176/jiaci.0956","DOIUrl":"10.18176/jiaci.0956","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"190-192"},"PeriodicalIF":6.1,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71414992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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