I Alobid, C Calvo-Henríquez, P Viveros-Díez, M López-Chacón, M J Rojas-Lechuga, C Langdon, C Marin, J Mullol
{"title":"Validation of a Visual Analog Scale for Loss of Smell as a Quick Test in Chronic Rhinosinusitis With Nasal Polyps.","authors":"I Alobid, C Calvo-Henríquez, P Viveros-Díez, M López-Chacón, M J Rojas-Lechuga, C Langdon, C Marin, J Mullol","doi":"10.18176/jiaci.0937","DOIUrl":"10.18176/jiaci.0937","url":null,"abstract":"<p><strong>Background and objectives: </strong>The diagnostic criteria of chronic rhinosinusitis with nasal polyps (CRSwNP) include olfactory dysfunction. We hypothesize that patients with CRSwNP can self-assess their sense of smell better using a visual analog scale (VAS) than using smell tests.</p><p><strong>Methods: </strong>A controlled cross-sectional study was performed. Adults diagnosed with severe CRSwNP waiting for endoscopic sinus surgery were included. A cohort of healthy controls was also studied. All participants completed the Barcelona Smell Test 24 (BAST-24), the 22-item Sinonasal Outcomes Test 22 (SNOT-22), and a VAS for loss of smell. Patients with CRSwNP underwent blood testing (eosinophil count, total serum IgE), computed tomography (Lund-Mackay Score), and nasal endoscopy.</p><p><strong>Results: </strong>The study population comprised 138 patients with severe CRSwNP and 40 controls. The BAST-24 identification score was strongly correlated with the VAS score in the CRSwNP group (p=-0.79, P<.001) but not in the control group (p=-0.14; P=.39), this difference between groups being statistically significant (P<.001). A significant correlation was found between SNOT-22 item 21 (loss of smell) and BAST-24 identification (p=-0.65, P<.001), this difference being statistically significant (Z=-2.43; P=.015). The area under the receiver operating curve was 0.85, with 72.5% sensitivity and 93.1% specificity.</p><p><strong>Conclusion: </strong>This study demonstrates a potential role of the VAS score for the screening of olfactory dysfunction in severe CRSwNP in daily clinical practice.</p>","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"377-384"},"PeriodicalIF":6.1,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10524499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R J Vieira, A M Pereira, N G Papadopoulos, T Zuberbier, N Pham-Thi, M Giovannini, E Melén, L F Azevedo, J A Fonseca, J Bousquet, B Sousa-Pinto
{"title":"Impact of Allergic Rhinitis on Academic Performance in Adolescents and Adults: a Bayesian Analysis of MASK-air® Real-world Direct Patient Data.","authors":"R J Vieira, A M Pereira, N G Papadopoulos, T Zuberbier, N Pham-Thi, M Giovannini, E Melén, L F Azevedo, J A Fonseca, J Bousquet, B Sousa-Pinto","doi":"10.18176/jiaci.1010","DOIUrl":"10.18176/jiaci.1010","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"409-411"},"PeriodicalIF":6.1,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Ruano-Zaragoza, G Araujo-Sanchez, S Gelis, D Loli-Ausejo, P Mir-Ihara, B Mascaró-Hereza, M C Sánchez-Fernández, M Pascal, R Muñoz-Cano, J Bartra
{"title":"Gastrointestinal Symptoms: Under the Tip of the Iceberg in Lipid Transfer Protein Food Allergy.","authors":"M Ruano-Zaragoza, G Araujo-Sanchez, S Gelis, D Loli-Ausejo, P Mir-Ihara, B Mascaró-Hereza, M C Sánchez-Fernández, M Pascal, R Muñoz-Cano, J Bartra","doi":"10.18176/jiaci.1006","DOIUrl":"10.18176/jiaci.1006","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"404-406"},"PeriodicalIF":6.1,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Montoro, D Antolín-Amérigo, M Artés, A Izquierdo-Domínguez, J J Zapata, P Mur, T Carrillo, I Antépara, F Feo, A Moral, A Valero
{"title":"Impact of Climate Change-Related Environmental Factors on Allergen Production and the Epidemiology and Severity of Allergic Diseases.","authors":"J Montoro, D Antolín-Amérigo, M Artés, A Izquierdo-Domínguez, J J Zapata, P Mur, T Carrillo, I Antépara, F Feo, A Moral, A Valero","doi":"10.18176/jiaci.0988","DOIUrl":"10.18176/jiaci.0988","url":null,"abstract":"<p><strong>Background: </strong>Allergic disease affects up to 40% of the adult population worldwide. This percentage is increasing as a result of environmental changes related to global warming.</p><p><strong>Methods: </strong>We undertook a systematic review of the literature to identify and evaluate current evidence on the impact of climate change-related environmental factors on allergen production and the epidemiology and severity of allergic diseases. We applied the Population, Exposure, Comparison, Outcome (PECO) criteria to guide our literature searches of the PubMed and Cochrane databases (January 1, 2016 to December 31, 2021). Study outcomes were categorized and grouped to facilitate data synthesis. Outcomes were classified as significant (P<.05), nonsignificant (P>.05), or undetermined (P value not reported). Study quality was assessed using the Mixed Methods Appraisal Tool.</p><p><strong>Results: </strong>Of 195 studies, 40 were considered relevant, and 9 provided data that could be included in the quantitative data synthesis. Environmental factors, including the presence of pollutants, temperature, and drought influenced the type, volume, and timing of exposure to local aeroallergens. The most relevant environmental factor was the presence of environmental pollutants, of which tropospheric ozone was the most frequently associated with changes in allergen production and prevalence and severity of allergic disease. Several publications also demonstrated the impact of environmental factors on health care burden.</p><p><strong>Conclusions: </strong>Climate change-related environmental factors worsened allergic disease in terms of prevalence, severity, and health care burden owing to alterations in allergen exposure (volume and type), with the presence of pollutants such as ozone being the most common drivers of this increase.</p>","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"358-366"},"PeriodicalIF":6.1,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139466709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H R Hernández-Suárez, I Bartha, E Lasa-Luaces, M Rodríguez-Álvarez, T Garriga-Baraut
{"title":"Adolescents and Vaping: The Essentials.","authors":"H R Hernández-Suárez, I Bartha, E Lasa-Luaces, M Rodríguez-Álvarez, T Garriga-Baraut","doi":"10.18176/jiaci.1014","DOIUrl":"10.18176/jiaci.1014","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"427-429"},"PeriodicalIF":6.1,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E Ramírez-Mateo, I Elías-Sáenz, C Fernández-Lozano, A Carrón-Herrero, E Solano-Solares, D González-De-Olano
{"title":"Allergy to White Perilla and Cross-reactivity With Sesame.","authors":"E Ramírez-Mateo, I Elías-Sáenz, C Fernández-Lozano, A Carrón-Herrero, E Solano-Solares, D González-De-Olano","doi":"10.18176/jiaci.1016","DOIUrl":"10.18176/jiaci.1016","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"421-423"},"PeriodicalIF":6.1,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B Andrés-López, M T Dordal Culla, R Lleonart Bellfill
{"title":"Hypersensitivity to Bismuth Subcitrate.","authors":"B Andrés-López, M T Dordal Culla, R Lleonart Bellfill","doi":"10.18176/jiaci.1018","DOIUrl":"10.18176/jiaci.1018","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"423-424"},"PeriodicalIF":6.1,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Eosinophilic Granulomatosis With Polyangiitis Triggered by an Arthropod Bite and Complicated by Renal and Hepatic Infarction and Pulmonary Embolism: A Case Report.","authors":"Y Yu, H Wang, W Weng, L Ma","doi":"10.18176/jiaci.1013","DOIUrl":"10.18176/jiaci.1013","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"419-421"},"PeriodicalIF":6.1,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141789711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Bautista-Villanueva, M Mateos-Salvador, R Arrojo Fuentes, M J Rial
{"title":"Successful Desensitization to Tezepelumab in a Polysorbate-Allergic Patient.","authors":"S Bautista-Villanueva, M Mateos-Salvador, R Arrojo Fuentes, M J Rial","doi":"10.18176/jiaci.1007","DOIUrl":"10.18176/jiaci.1007","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"417-419"},"PeriodicalIF":6.1,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141789712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Méar, M Babin, F Tisserand, C André, P Beriziky, H Maillard
{"title":"Cross-reactivity to Hydroxypropyl Methylcellulose and Hydroxyethyl Cellulose in a Patient Allergic to Carboxymethylcellulose: A Case Report.","authors":"A Méar, M Babin, F Tisserand, C André, P Beriziky, H Maillard","doi":"10.18176/jiaci.1019","DOIUrl":"10.18176/jiaci.1019","url":null,"abstract":"","PeriodicalId":50173,"journal":{"name":"Journal of Investigational Allergology and Clinical Immunology","volume":" ","pages":"425-426"},"PeriodicalIF":6.1,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}