Journal of Pediatric Ophthalmology & Strabismus最新文献_第3页

Ophthalmic Outcomes in Children With Spina Bifida Myelomeningocele in Ireland. 爱尔兰脊髓脊膜膨出儿童脊柱裂的眼科预后。

IF 1 4区医学

Journal of Pediatric Ophthalmology & Strabismus Pub Date : 2025-05-01 Epub Date: 2025-01-21 DOI: 10.3928/01913913-20241210-03

Shane O'Regan, Michelle Dunne, Lauren Devitt, Treasa Murphy

{"title":"Ophthalmic Outcomes in Children With Spina Bifida Myelomeningocele in Ireland.","authors":"Shane O'Regan, Michelle Dunne, Lauren Devitt, Treasa Murphy","doi":"10.3928/01913913-20241210-03","DOIUrl":"10.3928/01913913-20241210-03","url":null,"abstract":"Purpose: To investigate the ophthalmic complications associated with spina bifida myelomeningocele (SBM) in Irish children and to evaluate the impact of spinal lesion levels and shunt status on visual outcomes.Methods: A retrospective audit was conducted on 129 children with SBM, examining visual acuity, refractive errors, strabismus, papilledema, optic atrophy, and cortical visual impairment (CVI). The median age of participants was 6.9 years (interquartile range [IQR] = 7.07), comprising 69 females (53.5%) and 60 males (46.5%). Data were analyzed using chi-square and Kruskal-Wallis tests to assess associations between spinal lesion levels, shunt status, and visual outcomes.Results: The majority of lesions were lumbar (60.47%), followed by sacral (20.16%), thoracic (18.60%), and occipital (0.78%). Ventriculoperitoneal shunts were present in 67.44% of participants. Most children had good visual acuity, with visual impairment observed in 18.2%. Significant refractive errors were present in 40.8% of cases, whereas strabismus was observed in 33.3% of patients, predominantly esotropia. Papilledema, optic atrophy, and CVI were present in 12.4%, 5.4%, and 4.7% of participants. Higher spinal lesion levels were significantly associated with worse visual acuity (P =.019), whereas ventriculoperitoneal shunt status was significantly associated with papilledema (P = .034) and significant refractive errors (P = .019). No significant associations were found for strabismus, optic atrophy, or CVI.Conclusions: Ophthalmic complications such as refractive errors, strabismus, and visual impairment are common in children with SBM. The authors found that higher spinal lesions were associated with worse visual acuity. Shunt placement was also associated with a history of papilledema and higher rates of significant refractive error. [J Pediatr Ophthalmol Strabismus. 2025;62(3):196-202.].","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"196-202"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tractional Retinal Detachment Secondary to CHRPE-Associated Hamartoma With Macular Involvement: A Case Report. 牵引性视网膜脱离继发于chrpe相关错构瘤伴黄斑受累1例报告。

IF 1 4区医学

Journal of Pediatric Ophthalmology & Strabismus Pub Date : 2025-05-01 DOI: 10.3928/01913913-20250312-05

Javier García-Bardera, María Pampillón-Albert, Belén Gutiérrez-Partida, Isabel Valls-Ferrán, Lorenzo López-Guajardo

引用次数: 0

Changes in PAX7 Positive Satellite Cells in Extraocular Muscle After Strabismus Surgery. 斜视术后眼外肌PAX7阳性卫星细胞的变化。

IF 1 4区医学

Journal of Pediatric Ophthalmology & Strabismus Pub Date : 2025-05-01 Epub Date: 2025-01-21 DOI: 10.3928/01913913-20241210-02

Eunseok Kang, Suk-Gyu Ha

{"title":"Changes in PAX7 Positive Satellite Cells in Extraocular Muscle After Strabismus Surgery.","authors":"Eunseok Kang, Suk-Gyu Ha","doi":"10.3928/01913913-20241210-02","DOIUrl":"10.3928/01913913-20241210-02","url":null,"abstract":"Purpose: To investigate the effects of recession or re-section surgery on PAX 7 positive satellite cells of the extraocular muscle (EOM) in rabbits.Methods: A total of 20 rabbits (40 eyes) were included in this study. The superior rectus muscle of the right eye was either recessed or resected. Recession surgeries were performed at a distance of 5 mm (5 rabbits) and 10 mm (5 rabbits) from the original insertion, whereas resection surgeries were performed at a distance of 4 mm (5 rabbits) and 8 mm (5 rabbits). The superior rectus (operated muscle), inferior rectus (antagonist muscle), and superior rectus of the contralateral eye (control) were extracted 4 weeks after surgery. The number of PAX7 positive satellite cells was analyzed using immunohistochemistry.Results: The number of PAX7 positive satellite cells in the operated and antagonist muscles was higher than that in the control muscle after all surgeries (P < .05, all). The number of PAX7 positive satellite cells in the operated and antagonist muscles after resection surgery was higher than that after recession surgery (P < .05, all). Howerver, there were no significant differences of PAX7 positive satellite cells in the operated and antagonist muscles in recession and resection surgery according to the surgical amount (P > .05, all).Conclusions: PAX7 positive satellite cells in the operated and antagonist muscles showed an increase after resection surgery compared to recession surgery. This suggests that the extent of EOM regeneration may vary depending on the surgical method used for strabismus surgery. [J Pediatr Ophthalmol Strabismus. 2025;62(3):190-195.].","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"190-195"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Palpebral Fissure Changes After Bilateral Recession Versus Unilateral Recession-Plication of Horizontal Rectus Muscles for Correction of Intermittent Exotropia. 双侧收缩与单侧收缩后睑裂的变化——运用水平直肌矫正间歇性外斜视。

IF 1 4区医学

Journal of Pediatric Ophthalmology & Strabismus Pub Date : 2025-05-01 Epub Date: 2024-12-30 DOI: 10.3928/01913913-20241121-01

Kareem B Elessawy, Marooj Mohamed Mahmoud Ibrahim, Rehab R Kassem, Heba M Fouad

{"title":"Palpebral Fissure Changes After Bilateral Recession Versus Unilateral Recession-Plication of Horizontal Rectus Muscles for Correction of Intermittent Exotropia.","authors":"Kareem B Elessawy, Marooj Mohamed Mahmoud Ibrahim, Rehab R Kassem, Heba M Fouad","doi":"10.3928/01913913-20241121-01","DOIUrl":"10.3928/01913913-20241121-01","url":null,"abstract":"Purpose: To compare changes of vertical palpebral fissure height after bilateral lateral rectus (BLR) recessions versus unilateral lateral rectus (LR) recession and medial rectus (MR) muscle scleral plication, for treatment of intermittent exotropia.Methods: This prospective, comparative, randomized study included 40 patients with intermittent exotropia who were divided into two groups: 20 patients who underwent BLR recessions (BLR recession group) and 20 patients who underwent unilateral LR recession and MR muscle scleral plication (recession-plication group). Eyelid evaluation included measurement of margin reflex distance 1 (MRD1) and margin reflex distance 2 (MRD2) at 1 week, 6 weeks, and 3 months postoperatively. Angle of deviation and any incomitance were also recorded at each visit.Results: There was no significant statistical difference in eyelid measurements after the surgery between both groups (P = 1.00). There was no significant statistical difference in ocular alignment after the surgery between both groups (P = 1.00). Also, there was no significant statistical difference in lateral incomitance after the surgery between both groups (P = 1.00).Conclusions: Both the unilateral recession and plication of horizontal rectus muscles technique and bilateral recession provide comparable surgical results for correction of exotropia without significant palpebral fissures changes or lateral incomitance. [J Pediatr Ophthalmol Strabismus. 2025;62(3):182-189.].","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"182-189"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Three-Muscle Surgery for Large- and Medium-Angle Intermittent Exotropia. 三肌手术治疗大、中角度间歇性外斜视。

IF 1 4区医学

Journal of Pediatric Ophthalmology & Strabismus Pub Date : 2025-04-24 DOI: 10.3928/01913913-20250312-03

Yuval Cohen, Leah Attal, Aviv Vidan, Yehuda Greenberger, Yair Morad, Otzem Chassid

{"title":"Three-Muscle Surgery for Large- and Medium-Angle Intermittent Exotropia.","authors":"Yuval Cohen, Leah Attal, Aviv Vidan, Yehuda Greenberger, Yair Morad, Otzem Chassid","doi":"10.3928/01913913-20250312-03","DOIUrl":"https://doi.org/10.3928/01913913-20250312-03","url":null,"abstract":"Purpose: To examine the success rate and the dose-response ratio of three-muscle compared to two-muscle surgery for the treatment of medium- and large-angle (20 to 45 prism diopters [PD]) intermittent exotropia.Methods: Medical records of patients who underwent strabismus surgery for treatment of intermittent exotropia were reviewed. Patients with exodeviation of 20 to 45 PD who underwent either bilateral lateral rectus recession (BLRc; two-muscle group) or BLR recession and unilateral medial rectus resection (BLRc+UMR; three-muscle group) were selected. Preoperative and postoperative deviation and amount of recessed and resected muscles were assessed. Successful surgery was defined as postoperative deviation of 10 PD or less of orthophoria at the last visit. Dose-response ratio was analyzed.Results: Forty-four patients were included. The mean age of patients at surgery was 11.85 ± 10.82 years (range: 4 to 54 years) and was comparable in both groups. The mean far preoperative deviation was lower for the two-muscle than the three-muscle group, and measured 29.7 ± 5.9 and 34.4 ± 7.1 PD, respectively (P = .019). At the last follow-up, successful motor outcomes for both distance and near were achieved in 70.5% and 84.6% in the two-muscle and three-muscle group, respectively. At the last follow-up, mean dose-response ratio was significantly higher for the three-muscle group (1.82 ± 0.58 and 2.72 ± 0.72 PD/mm for the two-muscle and three-muscle group, respectively; P < .0001). Overcorrections were similar in both groups.Conclusions: Primary repair surgery of intermittent exotropia with three-muscle surgery is an effective method of resolving 20 to 45 PD with excellent outcomes and a low risk of overcorrection. [J Pediatr Ophthalmol Strabismus. 20XX;XX(X):XXX-XXX.].","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"1-8"},"PeriodicalIF":1.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges and Complications in the Management of Systemic Diseases in Congenital Cataract Surgery. 先天性白内障手术中系统性疾病处理的挑战和并发症。

IF 1 4区医学

Journal of Pediatric Ophthalmology & Strabismus Pub Date : 2025-04-24 DOI: 10.3928/01913913-20250312-02a

Semih Çakmak, Tuğçe Özdemir, Basri Akdoğan, Nihan Aksu Ceylan, Emre Altinkurt

{"title":"Challenges and Complications in the Management of Systemic Diseases in Congenital Cataract Surgery.","authors":"Semih Çakmak, Tuğçe Özdemir, Basri Akdoğan, Nihan Aksu Ceylan, Emre Altinkurt","doi":"10.3928/01913913-20250312-02a","DOIUrl":"https://doi.org/10.3928/01913913-20250312-02a","url":null,"abstract":"Purpose: To examine the effects of accompanying systemic diseases on surgery preparation and follow-up in congenital and infantile cataract cases.Methods: The files of patients aged 0 to 12 months presenting to one clinic between January 2010 and January 2024 and scheduled for cataract surgery were retrospectively scanned. The patients' demographic data, gestational age, age at admission and surgery, accompanying systemic diseases, and systemic complications that developed before, during, and after surgery were recorded.Results: A total of 142 patients (75 girls, 67 boys) were included in the study. The average follow-up period was 30.6 ± 33.9 months (range: 2 to 159 months). Unilateral cataract surgery was performed in 45 (31.7%) patients and bilateral cataract surgery was performed in 97 (68.3%) patients. The average number of gestational age was 37.2 ± 3.4 week (range: 23 to 41 weeks). The average age at presentation was 4.22 ± 3.20 months (range: 1 to 12 months). Systemic pathology was present before surgery in 40 patients (28.2%). Neuromuscular system diseases were the most common accompanying systemic pathology (15 patients), followed by genetic diseases (13 patients). Eleven (7.7%) patients had facial anomalies, and 21 (14.8%) were at risk of malignant hyperthermia during anesthesia. Eighteen (12.7%) were defined as having difficult intubation, and 46 patients (32.4%) required postoperative pediatric intensive care. One patient died due to pneumonia during surgery preparations, and 4 patients died due to systemic complications unrelated to the surgery during the follow-up period.Conclusions: Congenital cataract cases require a multi-disciplinary approach to surgical planning that considers systemic comorbidities, anesthesia management, and postoperative follow-up. [J Pediatr Ophthalmol Strabismus. 20XX;XX(X):XXX-XXX.].","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"1-8"},"PeriodicalIF":1.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Establishing Normative Data for Pediatric Corneal Sensitivity. 建立儿童角膜敏感性的规范数据。

IF 1 4区医学

Journal of Pediatric Ophthalmology & Strabismus Pub Date : 2025-04-24 DOI: 10.3928/01913913-20250312-02

Pelin Akçay, Pelin Kiyat, Timur Köse, Ozlem Barut Selver

{"title":"Establishing Normative Data for Pediatric Corneal Sensitivity.","authors":"Pelin Akçay, Pelin Kiyat, Timur Köse, Ozlem Barut Selver","doi":"10.3928/01913913-20250312-02","DOIUrl":"https://doi.org/10.3928/01913913-20250312-02","url":null,"abstract":"Purpose: To define the normative data of corneal sensitivity in the pediatric age group, which currently lacks existing literature.Methods: The study included 122 children aged 5 to 18 years who had applied for a routine ophthalmological examination at the Ege University Department of Ophthalmology. A total of 122 right eyes were included in the study. The study excluded children with any ocular pathologies, any previous ocular surgery, a history of contact lens use, and systemic diseases such as diabetes mellitus. Corneal sensitivity values were determined by means of a Cochet-Bonnet esthesiometer, applied to five distinct regions of the cornea (central, superior, inferior, nasal, and temporal).Results: The mean age was 11.29 ± 4.6 years (range: 2 to 18 years), and the female/male ratio was 63/59. The mean corneal sensitivity values of the central cornea and four corneal regions (superior, inferior, temporal, and nasal) were 5.16 ± 0.47, 5.16 ± 0.48, 5.19 ± 0.47, 5.18 ± 0.46, and 5.18 ± 0.45 cm, respectively. A negative correlation was identified between age and corneal sensitivity. No statistically significant difference was observed in corneal sensitivity when comparing quadrants or genders (P > .05).Conclusions: Data delineating the typical values have been identified in adults and have been demonstrated to serve as a valuable diagnostic instrument, particularly in the context of neuropathy in diabetes. Nevertheless, to date, no normative data have been published for the pediatric age group. Therefore, this study makes a significant contribution to the field by pioneering the establishment of normative data for the pediatric age group regarding corneal sensitivity, as detected with the Cochet-Bonnet esthesiometer. [J Pediatr Ophthalmol Strabismus. 20XX;XX(X):XXX-XXX.].","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"1-6"},"PeriodicalIF":1.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Out-of-Pocket Expense for Surgical Chalazion Removal. 手术摘除白内障的自付费用。

IF 1 4区医学

Journal of Pediatric Ophthalmology & Strabismus Pub Date : 2025-03-26 DOI: 10.3928/01913913-20250227-04

Taimur Siddiqui, Jay Jaber, Ryan Sorensen, Patrick J Hunt, Richard C Allen, Katherine J Williams

{"title":"Out-of-Pocket Expense for Surgical Chalazion Removal.","authors":"Taimur Siddiqui, Jay Jaber, Ryan Sorensen, Patrick J Hunt, Richard C Allen, Katherine J Williams","doi":"10.3928/01913913-20250227-04","DOIUrl":"https://doi.org/10.3928/01913913-20250227-04","url":null,"abstract":"Purpose: To provide an improved accounting of the economic burden of chalazion removal for patients.Methods: A retrospective study approved by the institutional review board of patients who underwent surgical incision and drainage of a chalazion at a tertiary academic center from January 2011 to December 2020 was conducted. Patients were younger than 18 years with a diagnosis of chalazion requiring excision. Out-of-pocket expenses were defined as sum of procedure cost, facility fees, and anesthesia. Center for Medicare and Medicaid Services (CMS) physician fee schedule data and the study hospital's cost estimator were used. Out-of-pocket expenses were calculated and adjusted to 2020 dollars. The cumulative cost was calculated by factoring in the average rate of surgical re-intervention for a chalazion recurrence. Cost trends were tabulated and visualized.Results: The unadjusted, average total incision and drainage cost for chalazion from 2011 to 2020 was $543.42, increasing from $513.89 to $563.48 (+9.7%). Using costs adjusted to 2020 dollars, cost declines from $591.27 (2011) to $563.48 (2020, -4.93%) were uncovered. Using an averaged recurrence rate of 24.3%, the cumulative adjusted total cost of incision and drainage decreased from $734.95 (2011) to $700.41 (2020, -4.70%).Conclusions: Chalazion treatment costs declined from 2011 to 2020, suggesting potentially greater affordability for families. However, families should be counseled up front on potential future expenses with surgical intervention for a recurring chalazion. Understanding total costs for recurring chalazion by accounting for potential surgical re-intervention will help pediatric ophthalmologists provide more informed counseling regarding the total cost of treatment with an appreciation for potential future costs if surgical re-intervention is required. [J Pediatr Ophthalmol Strabismus. 20XX;XX(X):XXX-XXX.].","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"1-5"},"PeriodicalIF":1.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Botulinum Toxin A Versus Bilateral Medial Rectus Recession for Partially Accommodative Esotropia: A Systematic Review and Meta-Analysis. A型肉毒杆菌毒素与双侧内直肌收缩治疗部分调节性内斜视：一项系统综述和荟萃分析。

IF 1 4区医学

Journal of Pediatric Ophthalmology & Strabismus Pub Date : 2025-03-26 DOI: 10.3928/01913913-20250227-08

Sara Hira, Claudia Avilés Covarrubias, Andres Bravo-Gonzalez, Carlos Eduardo de Menezes E Souza Filho, Mariana Tosato Zinher

{"title":"Botulinum Toxin A Versus Bilateral Medial Rectus Recession for Partially Accommodative Esotropia: A Systematic Review and Meta-Analysis.","authors":"Sara Hira, Claudia Avilés Covarrubias, Andres Bravo-Gonzalez, Carlos Eduardo de Menezes E Souza Filho, Mariana Tosato Zinher","doi":"10.3928/01913913-20250227-08","DOIUrl":"https://doi.org/10.3928/01913913-20250227-08","url":null,"abstract":"Purpose: To perform a systematic review and meta-analysis comparing the efficacy of botulinum toxin A (BTX-A) and bilateral medial rectus recession (BMR) surgery for partially accommodative esotropia (PAET).Methods: PubMed, EMBASE, and the Cochrane database were searched on May 29, 2024 for studies comparing BTX-A and BMR in patients with PAET, reporting at least one outcome of interest. The odds ratio (OR) and 95% CI were used for binary outcomes. Heterogeneity was assessed using I2 statistics. The analysis was performed using R software version 4.3.2. The Risk of Bias Summary for Non-randomized Studies tool was used to assess the risk of bias.Results: Four observational studies comprising 521 patients were eligible for inclusion. BTX-A and BMR groups had comparable motor success rates (OR: 1.14; 95% CI: 0.27 to 4.81; P = .861; I2 = 88%). However, consecutive exotropia was reported exclusively after BMR only (OR: 0.08; 95% CI: 0.01 to 0.46; P = .004; I2 = 0%). All studies accounted for heterogeneity in the leave-one-out sensitivity analysis. Two studies were judged as moderate risk of bias and two as serious. Assessment of Grading of Recommendations Assessment Development and Evaluation resulted in moderate certainty in the outcome of motor success rates.Conclusions: BTX-A might be a good alternative to BMR in patients with PAET. Randomized controlled trials with larger sample sizes and longer duration of follow-up are needed. Studies should also focus on sensory outcomes in addition to motor outcomes. [J Pediatr Ophthalmol Strabismus. 20XX;XX(X):XXX-XXX.].","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"1-8"},"PeriodicalIF":1.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

One-Year Results of 0.01% and 0.05% Atropine Eye Drops in Childhood Myopia Progression. 0.01%和0.05%阿托品滴眼液治疗儿童近视进展的一年结果。

IF 1 4区医学

Journal of Pediatric Ophthalmology & Strabismus Pub Date : 2025-03-26 DOI: 10.3928/01913913-20250227-07

Sibel Coşkun Akdemir, Irfan Akalın, Betul Önal Günay

{"title":"One-Year Results of 0.01% and 0.05% Atropine Eye Drops in Childhood Myopia Progression.","authors":"Sibel Coşkun Akdemir, Irfan Akalın, Betul Önal Günay","doi":"10.3928/01913913-20250227-07","DOIUrl":"https://doi.org/10.3928/01913913-20250227-07","url":null,"abstract":"Purpose: To compare 0.01% and 0.05% atropine eye drops with every other day treatment for slowing myopia progression in children.Methods: Children aged 5 to 15 years who had myopia of -1.00 to 8.00 diopters (D), astigmatism less than -2.50 D, and myopic progression of at least 1.00 D in the past year were included in the retrospective study. The 0.01% and 0.05% atropine eye drops were applied every other day. At each visit, all patients underwent complete ophthalmic examination including cycloplegic refraction, axial length (AL), and photopic-mesopic pupil sizes. Spherical equivalent (SE), AL, and photopicmesopic pupil sizes were evaluated.Results: In total, 92 eyes of 46 patients were included in the study (22 in the 0.01% atropine group and 24 in the 0.05% atropine group). At the end of the 12-month follow-up period, the mean SE changes were -0.41 ± 0.28 and -0.19 ± 0.22 D in the 0.01% and 0.05% atropine groups, respectively (P < .001). The AL changes were 0.19 ± 0.16 and 0.16 ± 024 mm in the 0.01% and 0.05% atropine groups, respectively (P = .52). Side effects such as photophobia and blurred near vision were not observed in the 0.01% atropine group, but in the 0.05% atropine group, photophobia was observed in 3(12.5%) cases and blurred near vision was observed in 8 (33%) cases.Conclusions: The 0.01% and 0.05% atropine eye drops significantly slowed the progression of myopia with every other day use. The 0.01% atropine was better tolerated than 0.05% atropine. [J Pediatr Ophthalmol Strabismus. 20XX;X(X):XXX-XXX.].","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"1-6"},"PeriodicalIF":1.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0