Journal of Pediatric Ophthalmology & Strabismus最新文献

{"title":"Utility of Fluorescein Angiography for Early Detection of Familial Exudative Vitreoretinopathy in Neurodevelopmental Disorder With Spastic Diplegia and Visual Defects Due to <i>CTNNB1</i> Variants.","authors":"Guillermo A Requejo Figueroa, Denise J Morgan, Griffin J Jardine, Marielle P Young, Eileen S Hwang","doi":"10.3928/01913913-20241122-01","DOIUrl":"10.3928/01913913-20241122-01","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate whether wide-angle fluorescein angiography (FA) was useful for detecting familial exudative retinopathy (FEVR) in patients with neurodevelopmental disorder with spastic diplegia and visual defects (NEDSDV).</p><p><strong>Methods: </strong>This was a retrospective chart review from 2013 to 2023 of all consecutive patients with NEDSDV and pathogenic or likely pathogenic <i>CTNNB1</i> variants.</p><p><strong>Results: </strong>Seven patients (four females, three males) were seen in the ophthalmology clinic (median age: 14 months). One patient presented with a retinal fold in one eye, was observed without FA, and later developed a tractional retinal detachment involving the macula in the contralateral eye. Another patient observed without FA lost vision due to vitreous hemorrhage. Five patients who lacked signs of FEVR in clinic underwent FA under anesthesia; three showed retinal neovascularization or leakage requiring treatment, one showed mild avascularity, and one was normal.</p><p><strong>Conclusions: </strong>Despite reassuring eye examinations in the clinic, two patients with NEDSDV experienced vision loss from FEVR, and three patients were found by FA to require treatment. FA aided in the detection of FEVR in these patients. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2025;62(3):166-172.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"166-172"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy and Readability of ChatGPT Responses to Patient-Centric Strabismus Questions.","authors":"Ashlyn A Gary, James M Lai, Elyana V T Locatelli, Michelle M Falcone, Kara M Cavuoto","doi":"10.3928/01913913-20250110-02","DOIUrl":"10.3928/01913913-20250110-02","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the medical accuracy and readability of responses provided by ChatGPT (OpenAI), the most widely used artificial intelligence-powered chatbot, regarding questions about strabismus.</p><p><strong>Methods: </strong>Thirty-four questions were input into ChatGPT 3.5 (free version) and 4.0 (paid version) at three time intervals (day 0, 1 week, and 1 month) in two distinct geographic locations (California and Florida) in March 2024. Two pediatric ophthalmologists rated responses as \"acceptable,\" \"accurate but missing key information or minor inaccuracies,\" or \"inaccurate and potentially harmful.\" The online tool, Readable, measured the Flesch-Kincaid Grade Level and Flesch Reading Ease Score to assess readability.</p><p><strong>Results: </strong>Overall, 64% of responses by ChatGPT were \"acceptable;\" but the proportion of \"acceptable\" responses differed by version (47% for ChatGPT 3.5 vs 53% for 4.0, <i>P</i> < .05) and state (77% of California vs 51% of Florida, <i>P</i> < .001). Responses in Florida were more likely to be \"inaccurate and potentially harmful\" compared to those in California (6.9% vs. 1.5%, <i>P</i> < .001). Over 1 month, the overall percentage of \"acceptable\" responses increased (60% at day 0, 64% at 1 week, and 67% at 1 month, <i>P</i> > .05), whereas \"inaccurate and potentially harmful\" responses decreased (5% at day 0, 5% at 1 week, and 3% at 1 month, <i>P</i> > .05). On average, responses scored a Flesch-Kincaid Grade Level score of 15, equating to a higher than high school grade reading level.</p><p><strong>Conclusions: </strong>Although most of ChatGPT's responses to strabismus questions were clinically acceptable, there were variations in responses across time and geographic regions. The average reading level exceeded a high school level and demonstrated low readability. Although ChatGPT demonstrates potential as a supplementary resource for parents and patients with strabismus, improving the accuracy and readability of free versions of ChatGPT may increase its utility. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2025;62(3):220-227.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"220-227"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term Motor and Sensory Outcomes After Unilateral Lateral Rectus Recession-Medial Rectus Resection for Infantile Constant Exotropia.","authors":"Kanwar Mohan, Suresh Kumar Sharma","doi":"10.3928/01913913-20241210-04","DOIUrl":"10.3928/01913913-20241210-04","url":null,"abstract":"<p><strong>Purpose: </strong>To report long-term motor and sensory outcomes after unilateral lateral rectus recession-medial rectus resection for infantile constant exotropia.</p><p><strong>Methods: </strong>The medical records of patients who had undergone unilateral lateral rectus recession-medial rectus resection for infantile constant exotropia who were followed up postoperatively for a minimum of 4 years were reviewed retrospectively.</p><p><strong>Results: </strong>A total of 20 patients were included. The mean age at surgery was 3.21 ± 1.54 years (range: 1.25 to 6.00 years). The mean duration of exodeviation was 2.99 ± 1.61 years (range: 9 months to 6 years). The mean angle of exodeviation was 70.1 ± 20.9 prism diopters (PD) (range: 35 to 90 PD). The median postoperative follow-up was 9.1 years (range: 4 to 24 years). Overall, 12 patients (60%) had surgical success at their last follow-up visit. Age at first surgery, cycloplegic refraction, strabismus duration, preoperative angle of deviation, presence of amblyopia, and the number of exotropia surgeries did not predict motor outcome after surgery. At the last follow-up visit, 20% of patients had residual exotropia and 15% had recurrent exotropia. Peripheral binocular single vision was achieved in 25% of patients and stereopsis in none. Age at first surgery, strabismus duration, and surgical outcome had no effect on sensory outcome.</p><p><strong>Conclusions: </strong>In this study, 60% of patients achieved a successful long-term motor outcome and 25% achieved peripheral binocular single vision after unilateral recession-resection for infantile constant exotropia. Stereopsis outcome was nil. Age at surgery and duration of strabismus had no effect on motor and sensory outcomes. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2025;62(3):203-210.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"203-210"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conjunctival Solitary Fibrous Tumor Masquerading as Conjunctival Hemangioma: A Case Report.","authors":"Noor Widyani Ahmad Shahaime, Wan Haslina Wan Abdul Halim, Othmaliza Othman, Meng Hsien Yong, Chenshen Lam, Mazaya Mahmud, Fazarina Mohammed","doi":"10.3928/01913913-20250312-06","DOIUrl":"https://doi.org/10.3928/01913913-20250312-06","url":null,"abstract":"<p><p>A 15-year-old girl presented with a painless, enlarging lesion on the left inferior conjunctiva, initially diagnosed as conjunctival hemangioma. Despite treatment with topical beta-blockers, the lesion continued to grow. Excision and histopathological examination confirmed the diagnosis of a conjunctival solitary fibrous tumor, highlighting the importance of considering rare lesions in the differential diagnosis. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2025;62(3):e35-e41.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":"62 3","pages":"e35-e41"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Failure to Thrive With Unilateral Proptosis and Xanthocoria in a Young Boy.","authors":"Robert J Medina, Rolika Bansal, Carol L Shields","doi":"10.3928/01913913-20241001-03","DOIUrl":"10.3928/01913913-20241001-03","url":null,"abstract":"","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"228"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Vision and Eye Movement Abnormalities in Children Referred to the Children's Epilepsy Surgery Service: A 5-Year Observational Study.","authors":"Shu-Yi Claire Chan, Penny Warnes, Maryama Warsame, Denize Atan","doi":"10.3928/01913913-20250103-01","DOIUrl":"10.3928/01913913-20250103-01","url":null,"abstract":"<p><strong>Purpose: </strong>To report the prevalence of visual acuity, visual field, and ocular motility problems in children with epilepsy referred to the Children's Epilepsy Surgery Service (CESS) for surgery.</p><p><strong>Methods: </strong>This was a retrospective observational study of all children referred to the CESS in Bristol between 2015 and 2020. Data extraction included age, age at epilepsy diagnosis, epilepsy etiology (as determined by seizure semiology, neuroimaging, and electroencephalography), anti-seizure drugs, visual acuity, visual field, ocular motility, and fundus imaging.</p><p><strong>Results: </strong>A total of 221 children with epilepsy were seen during the study period: 60% (132/221) had structural etiologies, 8% (18/221) were genetic, and in 28% (62/221) the etiology was unknown. Overall, 53% (117/221) were found to have abnormalities, particularly strabismus (16%, 36/221), visual field defects (14%, 27/198), and reduced visual acuity (12%, 26/219). Notably, 54% (63/117) of children with ophthalmic abnormalities were new diagnoses in the CESS clinic. Younger children and those with neurodevelopmental disorders were less likely to complete all vision tests.</p><p><strong>Conclusions: </strong>Ophthalmic abnormalities were prevalent among children referred for epilepsy surgery in Bristol and more than half were previously undiag-nosed. The data support the adoption of an orthopticled vision screening service for children with medically refractory epilepsy, structural etiologies, and focal seizures, to better support their needs in the community. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2025;62(3):211-219.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"211-219"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Onset of Diplopia.","authors":"Robert W Arnold, James A Deutsch, Gary Rogers, Leonard B Nelson","doi":"10.3928/01913913-20250409-01","DOIUrl":"https://doi.org/10.3928/01913913-20250409-01","url":null,"abstract":"","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":"62 3","pages":"157-159"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ophthalmic Outcomes in Children With Spina Bifida Myelomeningocele in Ireland.","authors":"Shane O'Regan, Michelle Dunne, Lauren Devitt, Treasa Murphy","doi":"10.3928/01913913-20241210-03","DOIUrl":"10.3928/01913913-20241210-03","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the ophthalmic complications associated with spina bifida myelomeningocele (SBM) in Irish children and to evaluate the impact of spinal lesion levels and shunt status on visual outcomes.</p><p><strong>Methods: </strong>A retrospective audit was conducted on 129 children with SBM, examining visual acuity, refractive errors, strabismus, papilledema, optic atrophy, and cortical visual impairment (CVI). The median age of participants was 6.9 years (interquartile range [IQR] = 7.07), comprising 69 females (53.5%) and 60 males (46.5%). Data were analyzed using chi-square and Kruskal-Wallis tests to assess associations between spinal lesion levels, shunt status, and visual outcomes.</p><p><strong>Results: </strong>The majority of lesions were lumbar (60.47%), followed by sacral (20.16%), thoracic (18.60%), and occipital (0.78%). Ventriculoperitoneal shunts were present in 67.44% of participants. Most children had good visual acuity, with visual impairment observed in 18.2%. Significant refractive errors were present in 40.8% of cases, whereas strabismus was observed in 33.3% of patients, predominantly esotropia. Papilledema, optic atrophy, and CVI were present in 12.4%, 5.4%, and 4.7% of participants. Higher spinal lesion levels were significantly associated with worse visual acuity (<i>P</i> =.019), whereas ventriculoperitoneal shunt status was significantly associated with papilledema (<i>P</i> = .034) and significant refractive errors (<i>P</i> = .019). No significant associations were found for strabismus, optic atrophy, or CVI.</p><p><strong>Conclusions: </strong>Ophthalmic complications such as refractive errors, strabismus, and visual impairment are common in children with SBM. The authors found that higher spinal lesions were associated with worse visual acuity. Shunt placement was also associated with a history of papilledema and higher rates of significant refractive error. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2025;62(3):196-202.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"196-202"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tractional Retinal Detachment Secondary to CHRPE-Associated Hamartoma With Macular Involvement: A Case Report.","authors":"Javier García-Bardera, María Pampillón-Albert, Belén Gutiérrez-Partida, Isabel Valls-Ferrán, Lorenzo López-Guajardo","doi":"10.3928/01913913-20250312-05","DOIUrl":"https://doi.org/10.3928/01913913-20250312-05","url":null,"abstract":"<p><p>Retinal hamartomas associated with hypertrophy of the retinal pigment epithelium are often linked to phakomatoses. This case report presents a 6-year-old patient with vision loss due to tractional rhegmatogenous retinal detachment. Surgical intervention (vitrectomy) improved retinal architecture and visual acuity, although significant baseline visual acuity loss persisted, suggesting that early surgery may prevent complications and optimize outcomes. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2025;62(3):e31-e34.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":"62 3","pages":"e31-e34"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Palpebral Fissure Changes After Bilateral Recession Versus Unilateral Recession-Plication of Horizontal Rectus Muscles for Correction of Intermittent Exotropia.","authors":"Kareem B Elessawy, Marooj Mohamed Mahmoud Ibrahim, Rehab R Kassem, Heba M Fouad","doi":"10.3928/01913913-20241121-01","DOIUrl":"10.3928/01913913-20241121-01","url":null,"abstract":"<p><strong>Purpose: </strong>To compare changes of vertical palpebral fissure height after bilateral lateral rectus (BLR) recessions versus unilateral lateral rectus (LR) recession and medial rectus (MR) muscle scleral plication, for treatment of intermittent exotropia.</p><p><strong>Methods: </strong>This prospective, comparative, randomized study included 40 patients with intermittent exotropia who were divided into two groups: 20 patients who underwent BLR recessions (BLR recession group) and 20 patients who underwent unilateral LR recession and MR muscle scleral plication (recession-plication group). Eyelid evaluation included measurement of margin reflex distance 1 (MRD1) and margin reflex distance 2 (MRD2) at 1 week, 6 weeks, and 3 months postoperatively. Angle of deviation and any incomitance were also recorded at each visit.</p><p><strong>Results: </strong>There was no significant statistical difference in eyelid measurements after the surgery between both groups (<i>P</i> = 1.00). There was no significant statistical difference in ocular alignment after the surgery between both groups (<i>P</i> = 1.00). Also, there was no significant statistical difference in lateral incomitance after the surgery between both groups (<i>P</i> = 1.00).</p><p><strong>Conclusions: </strong>Both the unilateral recession and plication of horizontal rectus muscles technique and bilateral recession provide comparable surgical results for correction of exotropia without significant palpebral fissures changes or lateral incomitance. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2025;62(3):182-189.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":" ","pages":"182-189"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}