Stereopsis Outcome in Refractive Accommodative Esotropia Successfully Treated With an Age of Onset Within 6 Months of Life.

Purpose: To investigate factors influencing stereopsis outcomes in patients with fully refractive accommodative esotropia (RAET) that developed within the first 6 months of life, and were successfully aligned within 10 prism diopters of orthophoria.

Methods: This retrospective study included 29 patients with RAET, aged 6 months or younger at onset. Patients were divided into two groups based on stereopsis outcomes: measurable (n = 11) and nil (n = 18). The study variables included age at esotropia onset, age at initial visit, age at first wearing of glasses, duration of misalignment, duration of treatment, cycloplegic refraction, and angle of ocular deviation. Additionally, the relationship between the timing of initial wearing of glasses (≤ 8 months) and stereopsis outcomes was analyzed.

Results: No significant differences were found between the measurable and nil groups in any of the measured variables. The frequencies of measurable stereopsis outcomes also showed no significant differences between patients with a duration of misalignment of 4 months or less (n = 7) and those with a duration of more than 4 months (n = 22) (57% [4/7] vs 32% [7/22]; P = .375, Fisher's exact test). However, the frequencies of measurable stereopsis outcomes in patients treated with first wearing of cycloplegic glasses at 8 months or younger (n = 9) were significantly higher than those treated with first wearing of cycloplegic glasses at older than 8 months (n = 20) (66% [6/9] vs 25% [5/20]; P = .048, Fisher's exact test).

Conclusions: The most important factor associated with a measurable stereopsis outcome was age at first wearing of cycloplegic glasses (≤ 8 months), with 66% of these patients achieving measurable stereopsis. [J Pediatr Ophthalmol Strabismus. 20XX;X(X):XXX-XXX.].