Isis Zhang, Rudolph S Wagner, James K Liu, Matthew Turbin, Roger E Turbin
{"title":"Iatrogenic Pseudo-Duane Retraction Syndrome Following Orbitozygomatic Craniotomy.","authors":"Isis Zhang, Rudolph S Wagner, James K Liu, Matthew Turbin, Roger E Turbin","doi":"10.3928/01913913-20231214-04","DOIUrl":"10.3928/01913913-20231214-04","url":null,"abstract":"<p><p>Restrictive strabismus is a known complication of orbitozygomatic craniotomy. However, a pseudo-Duane syndrome has not been described following this procedure. The authors describe a 58-year-old woman who after craniotomy developed incomitant left exotropia with an adduction deficit; the globe retracted and palpebral fissure narrowed with attempted ocular adduction. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2024;61(1):e7-e10.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139673478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Emergence of Female Pediatric Ophthalmologists Has Been Important and Necessary.","authors":"Leonard B Nelson","doi":"10.3928/01913913-20231219-01","DOIUrl":"10.3928/01913913-20231219-01","url":null,"abstract":"","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139673482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura E Andaluz-Scher, Omar J Farhat, Peter J Ness, John W Simon
{"title":"Late Recurrence of Anisometropic Amblyopia.","authors":"Laura E Andaluz-Scher, Omar J Farhat, Peter J Ness, John W Simon","doi":"10.3928/01913913-20231214-05","DOIUrl":"10.3928/01913913-20231214-05","url":null,"abstract":"<p><p>A 15-year-old boy whose anisometropic amblyopia was effectively treated with glasses was examined. Despite years of stability, his visual acuity decreased from 20/20 to 20/60 with poor glasses compliance. Although amblyopia recurrence is well recognized, this case emphasizes potential late recurrence after prolonged success. Fortunately, he improved to 20/20 after improved compliance. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2024;61(1):e11-e12.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139673479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neha Garg, Ezra Cohen, Edmund Tsui, Kara C LaMattina
{"title":"The Effect of Leflunomide as Adjunctive Therapy With a TNF Inhibitor in Pediatric Patients With Uveitis.","authors":"Neha Garg, Ezra Cohen, Edmund Tsui, Kara C LaMattina","doi":"10.3928/01913913-20221118-03","DOIUrl":"10.3928/01913913-20221118-03","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the effectiveness of leflunomide as adjunctive therapy with anti-tumor necrosis factor (anti-TNF) agents in pediatric patients with uveitis who are not able to tolerate methotrexate.</p><p><strong>Methods: </strong>A retrospective case series was performed of pediatric patients who were receiving leflunomide in conjunction with anti-TNF agent therapy after intolerance to a combination of methotrexate with anti-TNF therapy. Dose and duration of methotrexate, leflunomide, and anti-TNF therapy were recorded. Extensive history, demographics, laboratory data, and uveitis flare rate were obtained.</p><p><strong>Results: </strong>A total of five children were included in the study. Most patients were initially receiving methotrexate and an anti-TNF agent was added subsequently due to inadequate response to monotherapy. After discontinuation of methotrexate, leflunomide was initiated with anti-TNF therapy. The replacement of methotrexate with leflunomide showed decreased side effects and was associated with lower flare rates and steroid-free remission.</p><p><strong>Conclusions: </strong>Leflunomide was found to be well tolerated and effective at maintaining uveitis quiescence in conjunction with anti-TNF agents in pediatric patients who do not tolerate methotrexate. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2023;60(6):417-420.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10419982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Use of Telemedicine in Managing Adult Strabismus: Does It Save Time?","authors":"Rudolph S Wagner","doi":"10.3928/01913913-20231025-01","DOIUrl":"10.3928/01913913-20231025-01","url":null,"abstract":"","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Terry Lee, Federico G Velez, Nelli Galoyan, Vinod K Prasad, Mays A El-Dairi
{"title":"Optical Coherence Tomography Findings in Cherry-Red Spot: Implications for Understanding Pathophysiology and Visual Prognosis.","authors":"Terry Lee, Federico G Velez, Nelli Galoyan, Vinod K Prasad, Mays A El-Dairi","doi":"10.3928/01913913-20230123-01","DOIUrl":"10.3928/01913913-20230123-01","url":null,"abstract":"<p><strong>Purpose: </strong>To report optical coherence tomography (OCT) findings of cherry-red spots from Tay-Sachs and Niemann-Pick disease.</p><p><strong>Methods: </strong>Consecutive patients with Tay-Sachs and Niemann-Pick disease evaluated by the pediatric transplant and cellular therapy team, for whom a handheld OCT scan was obtained, were included. Demographic information, clinical history, fundus photography, and OCT scans were reviewed. Two masked graders evaluated each of the scans.</p><p><strong>Results: </strong>The study included 3 patients with Tay-Sachs disease (5, 8, and 14 months old) and 1 patient with Niemann-Pick disease (12 months old). All patients had bilateral cherry-red spots on fundus examination. In all patients with Tay-Sachs disease, handheld OCT revealed parafoveal ganglion cell layer (GCL) thickening, increased nerve fiber layer, and GCL reflectivity, and different levels of residual normal signal GCL. The patient with Niemann-Pick disease had similar parafoveal findings, but there was a thicker residual GCL. Sedated visual evoked potentials were unrecordable in all 4 patients despite 3 of them demonstrating normal visual behavior for age. Patients with good vision had relative sparing of the GCL on OCT.</p><p><strong>Conclusions: </strong>The cherry-red spots in lysosomal storage diseases appear as perifoveal thickening and hyperreflectivity of the GCL on OCT. In this case series, residual GCL with normal signal proved to be a better biomarker for visual function than visual evoked potentials and could be considered for future therapeutic trials. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2023;60(6):435-440.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9300740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Choroidal Vascular Index in Patients With Attention-Deficit/Hyperactivity Disorder and Methylphenidate.","authors":"Hasan Kiziltoprak, Dilara Ozkoyuncu Kocabas, Gozde Aksoy Aydemir, Emine Merve Kalınlı, Emre Aydemir, Burak Oren","doi":"10.3928/01913913-20221026-01","DOIUrl":"10.3928/01913913-20221026-01","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate choroidal vascularity in children with attention-deficit/hyperactivity disorder (ADHD) who were not receiving therapy, children with ADHD who were regularly taking methylphenidate (MPH), and healthy controls.</p><p><strong>Methods: </strong>The study included three groups: patients with newly diagnosed ADHD without treatment, patients diagnosed as having ADHD who were already being treated with oral MPH, and controls. Both choroidal vascularity index (CVI) and choroidal thickness were measured using an enhanced-depth imaging mode of spectral-domain optical coherence tomography (EDIOCT) (Spectralis; Heidelberg Engineering GmbH).</p><p><strong>Results: </strong>There was a significant difference in CVI and stromal area between groups. Post-hoc univariate analysis showed that CVI was significantly lower in patients with ADHD treated with MPH compared with the other groups (<i>P</i> < .001, for each); however, there was no difference between the treatment-free ADHD group and controls (<i>P</i> = .305). In contrast, stromal area was significantly higher in patients with ADHD treated with MPH than the other groups (<i>P</i> < .001, for each group). The correlation of CVI with MPH treatment duration in patients with ADHD treated with MPH showed a significant, moderate negative correlation (<i>P</i> = .01, <i>r</i> = - 0.66).</p><p><strong>Conclusions: </strong>CVI is reduced in patients with ADHD treated with MPH, and the decrease in CVI becomes significant with increasing duration of MPH treatment. This result reflects an indirect effect of MPH treatment on choroidal vascular structures. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2023;60(6):411-416.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10419979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elise Timtim, Manoradhan Murugesan, Michael P Blair, Sarah Hilkert Rodriguez
{"title":"Association of Health Insurance Status With Severity and Treatment Among Infants With Retinopathy of Prematurity.","authors":"Elise Timtim, Manoradhan Murugesan, Michael P Blair, Sarah Hilkert Rodriguez","doi":"10.3928/01913913-20231026-01","DOIUrl":"https://doi.org/10.3928/01913913-20231026-01","url":null,"abstract":"<p><p>This study describes retinopathy of prematurity treatment practices using Medicaid and commercial claims databases. Infants with Medicaid tend to be sicker overall and have higher rates of retinopathy of prematurity requiring treatment than those with commercial insurance. Among patients who required treatment, those with Medicaid were more likely to receive anti-vascular endothelial growth factor than laser treatment. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2023;60(6):e75-e78.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caitlin P Green, Michael J Lai, Rujuta A Gore, Connie M Wu, Qiang Ed Zhang, James E Sharpe, Rebecca J Elias, Barry N Wasserman
{"title":"Novel Virtual Vision Screening Program: Give Kids Sight Day 2020.","authors":"Caitlin P Green, Michael J Lai, Rujuta A Gore, Connie M Wu, Qiang Ed Zhang, James E Sharpe, Rebecca J Elias, Barry N Wasserman","doi":"10.3928/01913913-20230118-03","DOIUrl":"10.3928/01913913-20230118-03","url":null,"abstract":"<p><strong>Purpose: </strong>To determine whether a low-technology novel virtual vision screening protocol can reliably screen pediatric visual acuity.</p><p><strong>Methods: </strong>Give Kids Sight Day (GKSD), an annual out-reach program, aims to provide free vision screening and ophthalmic care to underserved children in Philadelphia, Pennsylvania. Children were screened virtually through the low-technology protocol. Based on screening results, 152 children were provided in-person eye examinations. Data from in-person examinations were compared to data from virtual screenings for 151 children who were seen in-person.</p><p><strong>Results: </strong>Of 475 children screened virtually, 152 children were seen in-person for examination, and 151 children were included in the analysis. Results from 151 children (mean age: 10.7 years, age range: 5 to 18 years, 43% female, 28% speaking a non-English language) were reviewed. There was a moderate correlation (<i>R</i> = .64, <i>P</i> < .0001; n = 100 children) between screening and in-person visual acuity without refractive correction and a strong correlation (<i>R</i> = 0.82, <i>P</i> < .0001; n = 18 children) between screening and in-person visual acuity with refractive correction. Of the 140 children who were seen in-person, 133 children were provided glasses prescriptions. Seventeen children required a referral to a pediatric ophthalmologist for evaluation of ophthalmic conditions, most commonly strabismus (5.3%) and amblyopia (4%).</p><p><strong>Conclusions: </strong>The GKSD virtual visual acuity testing demonstrated good correlation with in-person visual acuity testing, supporting the virtual screening approach as a useful tool for future applications in widespread community vision outreach programs. Further studies are needed to refine virtual ophthalmic screening to optimize its applications in bridging the gaps in ophthalmic care. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2023;60(6):390-395.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9300741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tiffany A Eatz, Meghana Kalavar, Michael Birnhak, Hasenin Al-Khersan, Jayanth Sridhar, Kara M Cavuoto
{"title":"The Role of Social Media in Strabismus Surgical Experience.","authors":"Tiffany A Eatz, Meghana Kalavar, Michael Birnhak, Hasenin Al-Khersan, Jayanth Sridhar, Kara M Cavuoto","doi":"10.3928/01913913-20230323-02","DOIUrl":"10.3928/01913913-20230323-02","url":null,"abstract":"<p><strong>Purpose: </strong>To understand patients' strabismus surgery experience, including its impact on patients' appearance and psychosocial factors such as anxiety and depression, via trends on popular social media platforms.</p><p><strong>Methods: </strong>TikTok and Instagram were searched for the following post hashtags: \"#strabismus,\" \"#strabismussurgery,\" \"#crosseyed,\" and \"#lazyeye.\" Data regarding date of post, username, gender, city, state, United States or international location, surgical status (preoperative, perioperative, or postoperative), tone (positive or negative), place of treatment, type of post (photo or video), number of likes/views, and number of followers were recorded for statistical analysis.</p><p><strong>Results: </strong>A total of 790 posts (400 TikTok, 390 Instagram) were included. The majority (87.8%) had a positive tone, particularly for Instagram (Instagram = 97.7%, TikTok = 78.3%, <i>P</i> < .01). TikTok had significantly more likes/follower (<i>P</i> < .01), as did negative posts (<i>P</i> < .01). #Lazyeye gained significantly more traction than other hashtags (range: <i>P</i> < .001 to .006). There were no differences in likes/follower for treatment phase (preoperative/perioperative/postoperative), gender, or relative age of poster (adult/parent/child).</p><p><strong>Conclusions: </strong>These findings demonstrated that TikTok and Instagram users tend to share positive strabismus surgical experiences; however, negative posts were associated with more interactive responses from viewers. Colloquial hashtags (eg, #lazyeye) were more likely to gain traction than medical terms. TikTok posts were associated with more engagement than Instagram, which suggests TikTok may be a better platform going forward for patient outreach. <b>[<i>J Pediatr Ophthalmol Strabismus</i>. 2023;60(6):402-405.]</b>.</p>","PeriodicalId":50095,"journal":{"name":"Journal of Pediatric Ophthalmology & Strabismus","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9382857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}