Benjamin Forrest , J. Jack Johnstone , Babajide Adeyefa , Jack Mumford , M. Max Henderson , Elspeth Guthrie
{"title":"The experiences of liaison psychiatry outpatients during and subsequent to the COVID-19 pandemic.","authors":"Benjamin Forrest , J. Jack Johnstone , Babajide Adeyefa , Jack Mumford , M. Max Henderson , Elspeth Guthrie","doi":"10.1016/j.jpsychores.2024.111903","DOIUrl":"10.1016/j.jpsychores.2024.111903","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"186 ","pages":"Article 111903"},"PeriodicalIF":3.5,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142158266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Navigating bio-psychosocial pathways in the relationship between food insecurity and mobility in the elderly","authors":"Rizky Andana Pohan , Ririn Dwi Astuti , Putri Bunga Aisyah Pohan , Erfan Ramadhani , Rikas Saputra","doi":"10.1016/j.jpsychores.2024.111891","DOIUrl":"10.1016/j.jpsychores.2024.111891","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"186 ","pages":"Article 111891"},"PeriodicalIF":3.5,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142076029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcin Rzeszutek , Joanna Kowalkowska , Katarzyna Drabarek , Angelika Van Hoy , Katarzyna Schier , Maja Lis-Turlejska , Małgorzata Dragan , Paweł Holas , Dominika Maison , Elżbieta Litwin , Julia Wawrzyniak , Wiktoria Znamirowska , Szymon Szumiał , Małgorzata Desmond
{"title":"Adverse childhood experiences and alexithymia intensity as predictors of temporal dynamics of functioning in individuals with irritable bowel syndrome: A three-wave latent transition analysis","authors":"Marcin Rzeszutek , Joanna Kowalkowska , Katarzyna Drabarek , Angelika Van Hoy , Katarzyna Schier , Maja Lis-Turlejska , Małgorzata Dragan , Paweł Holas , Dominika Maison , Elżbieta Litwin , Julia Wawrzyniak , Wiktoria Znamirowska , Szymon Szumiał , Małgorzata Desmond","doi":"10.1016/j.jpsychores.2024.111904","DOIUrl":"10.1016/j.jpsychores.2024.111904","url":null,"abstract":"<div><h3>Objective</h3><p>Despite high prevalence of irritable bowel syndrome (IBS) and its significant negative impact on individuals' quality of life, its etiology remains poorly understood. This prospective study explored whether early life factors (adverse childhood experiences; ACEs) and alexithymia intensity, could explain IBS symptom severity and its effects on psychological functioning over time. We also compared the studied variables between an IBS sample and a healthy control group.</p></div><div><h3>Method</h3><p>Based on the Rome III Diagnostic Criteria for IBS, 245 individuals with a diagnosis of IBS were recruited from a national sample of Poles. The IBS sample completed the following psychometric questionaries in three waves, one month apart: Adverse Childhood Experiences Questionnaire, Toronto Alexithymia Scale, IBS Symptom Severity Score, Short Form Perceived Stress Scale, and Ultra-Brief Patient Health Questionnaire for Anxiety and Depression. Latent transition analysis was used to identify distinct profiles of IBS symptom dynamics.</p></div><div><h3>Results</h3><p>The IBS group reported a significantly higher number of ACEs, greater alexithymia severity, and more intense levels of stress, anxiety, and depressive symptoms compared to the healthy controls. Four profiles of IBS individuals with distinct dynamics of IBS symptoms, stress, anxiety, and depressive symptoms were extracted, which correlated with the baseline number of ACEs and alexithymia intensity among participants.</p></div><div><h3>Conclusion</h3><p>Childhood adversity and associated problems in emotional processing affect IBS symptom severity. ACEs should be included in IBS screening and considered in the design of individualized multidisciplinary treatment approaches for IBS patients.</p></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"187 ","pages":"Article 111904"},"PeriodicalIF":3.5,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0022399924003167/pdfft?md5=88a3246e6742543ae20d0c8b08b30b7f&pid=1-s2.0-S0022399924003167-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142239303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Lahmann , M. Dieterich , S. Becker-Bense , G. Schmid-Mühlbauer
{"title":"Bilateral vestibulopathy – Loss of vestibular function and experience of emotions","authors":"C. Lahmann , M. Dieterich , S. Becker-Bense , G. Schmid-Mühlbauer","doi":"10.1016/j.jpsychores.2024.111894","DOIUrl":"10.1016/j.jpsychores.2024.111894","url":null,"abstract":"<div><h3>Objective</h3><p>The vestibular system is closely connected to emotion-processing neuronal circuits. Patients with bilateral vestibulopathy (BVP), a chronic loss of vestibular function, show remarkably lower rates of psychiatric comorbidities and vertigo-related anxiety (VRA) than those with episodic vertigo/dizziness (v/d). This study aimed to evaluate whether patients with BVP differ from those with episodic v/d in terms of VRA, general anxiety, and cognitions about body and health.</p></div><div><h3>Methods</h3><p>This cross-sectional study involved a subsample of 202 patients with episodic v/d (i.e., vestibular migraine, vestibular paroxysmia, or Menière's disease) and 43 patients with BVP. All patients underwent standardised neurological/neurotological examinations, structured clinical interviews (SCID-I), and self-report questionnaires, such as the Vertigo Handicap Questionnaire (VHQ), Beck Anxiety Inventory (BAI), Trait Anxiety from the State-Trait-Anxiety Inventory (STAI-T), and Cognitions About Body and Health questionnaire (CABAH). Non-parametric tests were used for analysis. Due to multiple testing, the significance level was set at <em>p</em> ≤ .008.</p></div><div><h3>Results</h3><p>Patients with episodic v/d exhibited higher VRA levels than those with BVP. However, this difference was not statistically significant (<em>p</em> = .04; <em>r</em> = 0.15, small effect). Additionally, patients with BVP reported more catastrophizing cognitions (<em>p</em> < .001; <em>r</em> = 0.25, small effect) and bodily weakness (<em>p</em> = .003; <em>r</em> = 0.22, small effect) compared to those with episodic v/d. There were no differences in general anxiety levels (BAI and STAI-T) between patients with v/d and those with BVP.</p></div><div><h3>Conclusion</h3><p>Patients with episodic v/d and BVP differed in their appraisal (cognition). The difference in VRA (subjective feeling) was not statistically significant. These preliminary results are discussed using a component approach to emotions.</p></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"186 ","pages":"Article 111894"},"PeriodicalIF":3.5,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0022399924003064/pdfft?md5=fe9a7534299f0230ce466761f149073c&pid=1-s2.0-S0022399924003064-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142049232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iman Elfeddali , Willem Johan Kop , Margot Metz , Linh Nguyen , Jennifer Sweetman , Jonathan Gower , Christina M. van der Feltz-Cornelis , Arjan C. Videler
{"title":"Research priorities for medically not yet explained symptoms expressed by patients, carers, and healthcare professionals in the Netherlands following the James Lind Alliance priority setting partnership approach","authors":"Iman Elfeddali , Willem Johan Kop , Margot Metz , Linh Nguyen , Jennifer Sweetman , Jonathan Gower , Christina M. van der Feltz-Cornelis , Arjan C. Videler","doi":"10.1016/j.jpsychores.2024.111890","DOIUrl":"10.1016/j.jpsychores.2024.111890","url":null,"abstract":"<div><h3>Objective</h3><p>Experiencing physical symptoms that are medically not yet explained (MNYES) is associated with considerable burden in daily life. Research priorities in this area have been primarily investigator-driven. The present study identifies the top 10 research priorities, incorporating the views of patients, carers and healthcare professionals.</p></div><div><h3>Methods</h3><p>This study used the Priority Setting Partnership approach in collaboration with the James Lind Alliance (JLA). The priority setting approach combines survey-based data from patients with a specific disorder/condition and relevant stakeholders (i.e., caregivers and healthcare professionals) with input from group meetings and a final priority setting consensus meeting. There were three consecutive phases: (1) online survey with an open-ended question to collect topics for future scientific research (<em>N</em> = 345 participants); (2) an online survey among stakeholders to prioritise the research questions generated in Phase 1 (<em>N</em> = 400); and (3) a final multi-stakeholder consensus meeting, held over two half-days to determine the final top 10 research priorities for the Netherlands (day 1 <em>N</em> = 25, day 2 <em>N</em> = 24).</p></div><div><h3>Results</h3><p>Phase 1 resulted in 572 topics, which were reduced to 37 summary research questions. Phase 2 resulted in 18 research priorities, that were ranked and the top 10 priorities were established during the final consensus meeting. The top 10 research priorities included three main themes: optimising efficient diagnosis and treatment, aetiology and prevention, and coping with MNYES.</p></div><div><h3>Conclusion</h3><p>The top 10 priorities provide insight into what is most important for future research into MNYES from the perspective of patients, carers and healthcare professionals.</p></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"186 ","pages":"Article 111890"},"PeriodicalIF":3.5,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142086879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ning Li , Dinglong Xue , Xu Zhao, Lijun Li, Kaiya Men, Jiaxin Yang, Hao Jiang, Qingwei Meng, Shuai Zhang
{"title":"Sleep disturbance as a poor prognostic predictor in patients with advanced non-small-cell lung cancer treated with immune checkpoint inhibitors: A prospective study","authors":"Ning Li , Dinglong Xue , Xu Zhao, Lijun Li, Kaiya Men, Jiaxin Yang, Hao Jiang, Qingwei Meng, Shuai Zhang","doi":"10.1016/j.jpsychores.2024.111892","DOIUrl":"10.1016/j.jpsychores.2024.111892","url":null,"abstract":"<div><h3>Background</h3><p>Sleep disturbances are highly prevalent in oncology and often exacerbate symptoms, leading to reduced quality of life, which in turn may further affect the tolerability and efficacy of oncological treatments. Sleep disturbance and cancer have an intimate and complicated relationship, and may be a negative predictor of cancer treatment. The present study aimed to characterize the relationship between sleep disturbance and immune checkpoint inhibitor (ICI) therapy in patients with advanced non-small cell lung cancer (NSCLC).</p></div><div><h3>Methods</h3><p>Data from 171 patients with advanced NSCLC, who underwent ICI treatment between December 2020 and October 2022, were analysed in our prospective study. Sleep disturbances were evaluated according to the Pittsburgh Sleep Quality Index (PSQI), with a cut-off value of 5, to investigate the impact of sleep disturbance on the survival of patients with NSCLC and the efficacy of ICI treatment.</p></div><div><h3>Results</h3><p>The median progression-free survival (PFS) was10.4 months (9 5% confidence interval [CI]:9.84–10.97). Univariate and multivariate analyses revealed that sleep disturbance and depressive symptom predicted worse prognosis with shortened PFS. Patients who experienced sleep disturbance exhibited a significant reduction in PFS (9.2 vs. 11.8 months; HR: 1.83 [9 5% CI 1.27–2.6 5]; <em>p</em> = 0.001), as did those with depressive states (HR 1.5 5 [9 5% CI 1.06–2.28]; <em>p</em> = 0.02 5). Additionally, patients with sleep disturbance and depressive symptoms exhibited significantly lower objective response rates and disease control rates.</p></div><div><h3>Conclusion</h3><p>Sleep disturbance could be a factor for prognosis in patients with advanced NSCLC undergoing first- or second-line treatment with ICIs, including shorter PFS and reduced efficacy.</p></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"186 ","pages":"Article 111892"},"PeriodicalIF":3.5,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142083877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Halifax somatic symptom disorder trial: A pilot randomized controlled trial of intensive short-term dynamic psychotherapy in the emergency department","authors":"Joel M. Town , Allan Abbass , Samuel Campbell","doi":"10.1016/j.jpsychores.2024.111889","DOIUrl":"10.1016/j.jpsychores.2024.111889","url":null,"abstract":"<div><h3>Background</h3><p>Patients commonly present at hospital Emergency Departments (ED) with distress that meet criteria for a Somatic Symptom and Related Disorder (SSRD). Without access to effective treatment, risk of ongoing patient disability and further ED visits is high.</p></div><div><h3>Method</h3><p>This pilot trial used a randomized parallel group design to test the efficacy of Intensive Short-Term Dynamic Psychotherapy (ISTDP). ED patients who met criteria for SSRD were recruited. The effects of ISTDP plus medical care as usual (MCAU) were judged through comparison against 8 weeks of MCAU plus wait-list symptom monitoring (WL-SM). The primary outcome was somatic symptom at 8 weeks. Patients allocated to WL-SM could cross-over to receive ISTDP and 6-month follow-up data was collected. Baseline measures of patient attachment style and alexithymia were collected to examine vulnerabilities to somatic symptoms. <span><span>ClinicalTrials.gov</span><svg><path></path></svg></span>: <span><span>NCT02076867</span><svg><path></path></svg></span>.</p></div><div><h3>Results</h3><p>Thirty-seven patients were randomized to 2 groups (ISTDP = 19 and WL-SM = 18). Multi-level modelling showed that change over time on somatic symptoms was significantly greater in the ISTDP group. Between-group differences were large at 8 weeks (Cohen's <em>d</em> = 0.94) and increased by end of treatment (Cohen's <em>d</em> = 1.54). Observed differences in symptoms of depression and illness anxiety were also large, favoring ISTDP, and effects were maintained at follow-up. Patients receiving ISTDP had reduced ED service utilization at 2-year follow-up.</p></div><div><h3>Conclusions</h3><p>ISTDP appears an efficacious treatment for SSRD and a larger randomized trial is justified.</p></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"187 ","pages":"Article 111889"},"PeriodicalIF":3.5,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erik van Twillert , Mirjam M.C. Hulsman , Lineke M. Tak
{"title":"Facilitating and hindering factors in the treatment of persistent somatic symptoms in migrants: A scoping review","authors":"Erik van Twillert , Mirjam M.C. Hulsman , Lineke M. Tak","doi":"10.1016/j.jpsychores.2024.111887","DOIUrl":"10.1016/j.jpsychores.2024.111887","url":null,"abstract":"<div><h3>Objective</h3><p>To identify facilitating and hindering factors in the treatment of persistent somatic symptoms (PSS) in migrants in psychiatry and other health care settings in Western countries.</p></div><div><h3>Methods</h3><p>A scoping literature review was conducted by searching PubMed and Embase, using combinations of search terms related to the treatment of PSS in migrants. Studies outside of the scope of current guidelines or limited to specific underlying diseases such as post-traumatic stress disorder (PTSD) or consequences of torture were excluded. Two independent reviewers verified that the studies met the inclusion criteria, assessed the quality of the studies, and identified and categorized facilitating and hindering treatment factors.</p></div><div><h3>Results</h3><p>Of the 347 unique citations identified in the initial the search, 18 studies met the inclusion criteria. These studies showed a wide variety in study design, interventions used, measurement instruments, and study quality. Common treatment adaptations related to: (a) translation and interpretation, (b) adaptation to lower educational levels, (c) culture-sensitive therapists and materials, (d) gender roles, (e) removal of practical barriers, (f) supportive treatment, and (g) nonverbal therapy forms. The most commonly mentioned influencing factors of treatment success related to: (a) body and experience-oriented treatment elements, (b) translation and communication, (c) cultural sensitivity, (d) group interaction, and (e) caring for one's own health.</p></div><div><h3>Conclusion</h3><p>This review provides an overview of available research on treatment adaptations for PSS in migratory background patients. Potential facilitating and hindering factors for treatment success that may be useful for healthcare providers treating PSS in patients with a migratory background were identified.</p></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"186 ","pages":"Article 111887"},"PeriodicalIF":3.5,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142098284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frank Euteneuer , Marie Neubert , Stefan Salzmann , Susanne Fischer , Ulrike Ehlert , Winfried Rief
{"title":"Biomarkers as predictors of CBT responsiveness in major depressive disorder: The role of heart rate variability and inflammation","authors":"Frank Euteneuer , Marie Neubert , Stefan Salzmann , Susanne Fischer , Ulrike Ehlert , Winfried Rief","doi":"10.1016/j.jpsychores.2024.111885","DOIUrl":"10.1016/j.jpsychores.2024.111885","url":null,"abstract":"<div><h3>Objective</h3><p>Biological risk factors for cardiovascular disease may relate to poor treatment responsiveness in major depressive disorder (MDD). These factors encompass low-grade inflammation and autonomic dysregulation, as indexed by decreased heart rate variability (HRV) and increased heart rate (HR). This secondary analysis examined whether higher levels of inflammatory markers or autonomic alterations relate to lower responsiveness to cognitive behavioral therapy (CBT) among individuals with MDD.</p></div><div><h3>Methods</h3><p>Eighty antidepressant-free patients with MDD were randomly assigned to 14 weeks of CBT or waitlist (WL). Potential biological moderators at study entry included HR and HRV (24-h, daytime, nighttime) and inflammatory markers such as C-reactive protein (CRP), interleukin (IL)-6, and tumor necrosis factor (TNF)-α. Forty non-clinical controls were involved to verify biological alterations in MDD at study entry. Depressive symptoms were assessed at baseline and at the end of treatment.</p></div><div><h3>Results</h3><p>Individuals with MDD exhibited reduced total 24-h HRV (i.e., triangular index) and daytime HRV (i.e., triangular index, HF-HRV, LF-HRV, RMSSD), as well as increased levels of inflammatory markers. Patients who received CBT exhibited stronger reductions in self- and clinician-rated depressive symptoms, compared to WL. False discovery rate-adjusted moderation analyses did not show overall moderating effects of biological measures on treatment responsiveness. However, higher CRP levels were specifically associated with poorer improvement in somatic depressive symptoms.</p></div><div><h3>Conclusions</h3><p>There was no overall evidence for a moderating role of inflammation or autonomic features in CBT responsiveness in MDD. Higher levels of CRP might, however, specifically be associated with less improvement in somatic depressive symptoms during CBT.</p></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"186 ","pages":"Article 111885"},"PeriodicalIF":3.5,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142049231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susana Sanduvete-Chaves , Salvador Chacón-Moscoso , Francisco J. Cano-García
{"title":"Effectiveness of psychological interventions to decrease cognitive fusion in patients with chronic pain: A systematic review and meta-analysis","authors":"Susana Sanduvete-Chaves , Salvador Chacón-Moscoso , Francisco J. Cano-García","doi":"10.1016/j.jpsychores.2024.111888","DOIUrl":"10.1016/j.jpsychores.2024.111888","url":null,"abstract":"<div><h3>Objective</h3><p>While there is sufficient evidence of Acceptance and Commitment Therapy's effectiveness in allowing patients to deal with chronic pain, the effectiveness in cognitive fusion, one of the six core components of the Psychology Flexibility Model, has yet to be established. The aim of this article is to assess whether psychological interventions decrease cognitive fusion.</p></div><div><h3>Methods</h3><p>The Web of Science, SCOPUS, Medline, and PsycINFO databases were searched for primary studies up to June 2024. Studies with a cognitive fusion measure in which chronic pain patients received a psychological intervention were included. A methodological quality scale was applied to the selected studies and the average effect sizes (Hedges g) were calculated.</p></div><div><h3>Results</h3><p>This review included 18 articles with 24 studies (19 pre-post/follow-up studies and five randomized control trials). Cognitive fusion decreased significantly after the intervention. The effect sizes were small/medium at post-test, <em>g</em> = -0.39, <em>p</em> < .001, 95% CI [-0.52, -0.26]; and medium at long-term follow-up, <em>g</em> = -0.55, <em>p</em> < .001, 95% CI [−0.74, -0.36]. A similar tendency was found for studies with RCTs at post-test, <em>g</em> = -0.61, <em>p</em> = .006, 95% CI [−1.05, -0.17], short-term follow-up, <em>g</em> = -0.79, <em>p</em> < .001, 95% CI [−1.18, -0.40] and long-term follow-up, <em>g</em> = -0.58, <em>p</em> = .003, 95% CI [-0.95, -0.20]). Moderator variables such as unemployment, gender, pain intensity, level of depression before the intervention, and duration and intervention modality were identified.</p></div><div><h3>Conclusion</h3><p>Psychological interventions tended to decrease cognitive fusion in chronic pain patients. Nonetheless, more clinical trials are needed to establish the role of cognitive fusion in psychological flexibility.</p></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"186 ","pages":"Article 111888"},"PeriodicalIF":3.5,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0022399924003003/pdfft?md5=dcb6716fb42a7bbdedfebdb12fa27495&pid=1-s2.0-S0022399924003003-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142088050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}