Maartje L.V. Kusters , Nina Kupper , Lars Brouwers , Mariska A.C. de Jongh
{"title":"A longitudinal latent class analysis of health-related quality of life post pelvic fractures; the BIOS cohort study","authors":"Maartje L.V. Kusters , Nina Kupper , Lars Brouwers , Mariska A.C. de Jongh","doi":"10.1016/j.jpsychores.2025.112504","DOIUrl":"10.1016/j.jpsychores.2025.112504","url":null,"abstract":"<div><h3>Background</h3><div>The objective of this study was to identify latent profiles in the HRQoL recovery of patients with pelvic fractures and examine demographic, psychological, and medical determinants.</div></div><div><h3>Methods</h3><div>184 patients (M<sub>age</sub> = 58.3 ± 16.9, 59 % male) from the BIOS study were included. HRQoL was assessed six times across two years. At 1-week post-injury, additional pre-injury HRQoL (EQ-5D-3L), psychological (HADS, IES), and functional (MPS, MAHS) measures were assessed. A 3-step repeated measures latent class analysis (RMLCA) identified latent profiles in HRQoL and examined their correlates.</div></div><div><h3>Results</h3><div>Four similar recovery profiles for the EQ-5D domains of VAS, mobility, and usual activities were identified: low/poor, intermediate/partial, high/full, and prominent improvement/fast & full recovery. For the EQ-5D domains of pain/discomfort, self-care, and anxiety/depression, three similar profiles were identified: poor recovery, partial recovery/intermediate problems, and full recovery/ no pain. Higher emotional distress, comorbidities, and complications were associated with the <em>low</em> VAS profile. Older age, pelvic ring fracture, pelvic surgery, higher ISS, lower emotional distress, and higher pre-injury HRQoL levels were associated with the <em>prominent improvement</em> VAS profile. Better physical functioning was associated with the <em>intermediate</em> and <em>high</em> VAS profiles.</div></div><div><h3>Conclusions</h3><div>Results unveiled person-level heterogeneity evidenced by the four latent recovery trajectories of HRQoL following pelvic fracture and their distinct associated covariates, among which psychological functioning, which significantly contributed to HRQoL recovery. Future research should focus on the development of adequate screening tools facilitating decision-making applications which in turn can optimize personalized treatment programs. The current findings offer valuable insights to aid in this developmental process<strong>.</strong></div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"201 ","pages":"Article 112504"},"PeriodicalIF":3.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145797687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Deokjong Lee , Kyung Mee Park , Jihye Kim , Sin Young Ko , Byeonghee Lee , Chae Jung Park , Kyoung Min Kim , Jin Young Park
{"title":"Single-arm longitudinal study to assess changes in insula functional connectivity following a mobile-based lifestyle intervention in adults with metabolic abnormalities","authors":"Deokjong Lee , Kyung Mee Park , Jihye Kim , Sin Young Ko , Byeonghee Lee , Chae Jung Park , Kyoung Min Kim , Jin Young Park","doi":"10.1016/j.jpsychores.2025.112498","DOIUrl":"10.1016/j.jpsychores.2025.112498","url":null,"abstract":"<div><h3>Backgrounds</h3><div>Mobile-based lifestyle intervention has been widely used to improve behavior for obesity and overweight. This study targeting adults with metabolic abnormalities aims to identify neural correlates related to weight loss due to mobile-based lifestyle intervention.</div></div><div><h3>Methods</h3><div>We conducted 8 weeks of mobile-based lifestyle intervention for 37 adults with metabolic abnormalities, including overweight. Participants underwent physical measurements, blood tests, psychometric questionnaires, and resting-state functional magnetic resonance imaging (fMRI) scans before and after the mobile-based intervention. For the resting-state fMRI, brain regions that showed changes in functional connectivity (FC) before and after mobile-based intervention were explored. Seed-based FC analysis was performed focusing on the subregions of the insular cortex.</div></div><div><h3>Results</h3><div>Participants significantly reduced body mass index (BMI) after mobile-based intervention. The degree of BMI reduction was significantly correlated with compliance with the intervention. In resting fMRI, FC of the posterior insula with the bilateral inferior parietal lobule and the left ventrolateral prefrontal cortex were enhanced after mobile-based intervention. The increase in FC between the posterior insula and the inferior posterior lobule showed a significant correlation with the decrease in binge eating scale scores.</div></div><div><h3>Conclusion</h3><div>The mobile-based lifestyle intervention significantly reduced weight and alleviated binge eating in adults with metabolic abnormalities. FC enhancement between the posterior insula and the frontoparietal regions was also observed after mobile-based lifestyle intervention. The relationship between these FC changes and strengthening weight control through mobile-based lifestyle intervention should be investigated through future research.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"201 ","pages":"Article 112498"},"PeriodicalIF":3.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145828992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors influencing excessive daytime sleepiness in obstructive sleep apnea: A retrospective cohort analysis integrating psychological assessment with polysomnography","authors":"Tuzhi Wang, Guoliang Peng, Kaiqi Huang, Hongyao Li, Yushan Chen, Xiaotao Zhang, Jiyang Pan","doi":"10.1016/j.jpsychores.2025.112502","DOIUrl":"10.1016/j.jpsychores.2025.112502","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to systematically evaluate psychological and polysomnographic parameters to analyze factors influencing excessive daytime sleepiness (EDS) in patients with obstructive sleep apnea (OSA).</div></div><div><h3>Methods</h3><div>We conducted a retrospective study of 318 adult OSA patients from a tertiary hospital sleep center. Participants underwent overnight polysomnography and completed questionnaires including the Epworth Sleepiness Scale (ESS), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), and Mood Disorder Questionnaire (MDQ). Statistical analyses involved univariate and multivariable logistic regression, with dose-response relationships assessed using restricted cubic splines.</div></div><div><h3>Results</h3><div>Among 318 OSA patients, 95 (29.9 %) had EDS (ESS >10). The EDS group showed significantly higher PHQ-9, GAD-7, and MDQ scores (all <em>p</em> < 0.05). Polysomnography revealed that EDS patients exhibited longer total sleep time, shorter wake after sleep onset, higher apnea-hypopnea index (AHI), elevated AHI during rapid eye movement sleep, and reduced lowest oxygen saturation. After adjusting for confounders, multivariable analysis identified PHQ-9 scores (OR = 1.12, 95 %CI:1.06–1.18), MDQ scores (OR = 1.16, 95 %CI:1.06–1.27), and respiratory arousal index (OR = 1.03, 95 %CI:1.01–1.05) as independent risk factors for EDS, all demonstrating significant positive linear dose-response relationships.</div></div><div><h3>Conclusion</h3><div>Our findings indicate that depressive symptoms, subclinical affective instability, and respiratory arousals are independently associated with EDS in OSA patients, with clear dose-response relationships. These results suggest that a multifactorial framework encompassing both psychological and physiological domains may be a valuable direction for understanding EDS, and warrant future investigation into the clinical value of integrated assessments.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"201 ","pages":"Article 112502"},"PeriodicalIF":3.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145850680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spirituality, collectivism, and psychosomatic health: A new pathway for culturally responsive mental health care in Southeast Asia","authors":"Ashari Mahfud , Anisatul Latifah , Citra Abriani Maharani , Shinta Mayasari , Muslikah , Marlin Sianturi","doi":"10.1016/j.jpsychores.2025.112481","DOIUrl":"10.1016/j.jpsychores.2025.112481","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"201 ","pages":"Article 112481"},"PeriodicalIF":3.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145679179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Personality traits as predictors of self-care agency in women with gynecological cancers: Cross-sectional study","authors":"Huri Çolu , Elif Uludağ","doi":"10.1016/j.jpsychores.2025.112503","DOIUrl":"10.1016/j.jpsychores.2025.112503","url":null,"abstract":"<div><h3>Background</h3><div>Gynecological cancers present a dual burden of physiological and psychosocial distress. Self-care agency defined as an individual's capacity to initiate and maintain health-related behaviors is critical for optimizing well-being in cancer patients. While psychological factors, particularly personality traits, are known to influence self-care in chronic illnesses, their role in gynecological oncology remains underexplored. This study aimed to determine whether personality traits predict self-care agency among women with gynecological cancers.</div></div><div><h3>Methods</h3><div>A descriptive, cross-sectional design was employed with 200 women recruited via convenience sampling. Data were collected using a demographic form, the Cervantes Personality Scale, and the Exercise of Self-Care Agency Scale. Simple linear regression analyses examined the predictive value of personality subscales on self-care agency.</div></div><div><h3>Results</h3><div>Personality traits were found to be significant predictors of self-care agency. Extroversion, emotional stability, and consistency explained 37.5 %, 20.1 %, and 30.4 % of the variance in self-care agency, respectively (<em>p</em> < 0.05). Women with higher levels of these traits demonstrated greater self-care capacity, while introversion, neuroticism, and inconsistency were linked to reduced self-care agency.</div></div><div><h3>Conclusions</h3><div>This study highlights the significant role of personality traits in influencing self-care agency in this population. Tailoring supportive care to address individual personality characteristics may improve self-management and overall treatment outcomes. Incorporating psychosocial assessments into routine care and developing targeted interventions could enhance quality of life. Future research should focus on intervention studies to validate these approaches and optimize personalized care strategies in gynecological oncology.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"201 ","pages":"Article 112503"},"PeriodicalIF":3.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145797686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariel Nöhre , Felix Klewitz , Maximilian Bauer-Hohmann , Eva Kyaw Tha Tun , Marietta Lieb , Yesim Erim , Uwe Tegtbur , Lena Schiffer , Lars Pape , Mario Schiffer , Martina de Zwaan
{"title":"Frequency and correlates of non-adherence in a large sample of adult patients after kidney transplantation: A cross-sectional KTx360° substudy","authors":"Mariel Nöhre , Felix Klewitz , Maximilian Bauer-Hohmann , Eva Kyaw Tha Tun , Marietta Lieb , Yesim Erim , Uwe Tegtbur , Lena Schiffer , Lars Pape , Mario Schiffer , Martina de Zwaan","doi":"10.1016/j.jpsychores.2025.112474","DOIUrl":"10.1016/j.jpsychores.2025.112474","url":null,"abstract":"<div><h3>Objective</h3><div>Non-adherence to immunosuppressive medication (ISM) is a common and preventable cause of graft loss after kidney transplantation (KTx). Adherence is a multifaceted construct influenced by various factors. Despite frequent reports linking non-adherence with multiple variables, results often seem contradictory. The lack of patient registers in Germany to encompass psychosocial aspects limits data to smaller, selective studies. The aim was to evaluate the frequency and correlates of non-adherence in a large sample of adult KTx patients.</div></div><div><h3>Methods</h3><div>This cross-sectional substudy was embedded within the structured follow-up program KTx360°. It took place at the transplant centers of Hannover Medical School, Hann. Münden and Erlangen in Germany between May 2017 and October 2020. 838 adult KTx patients participated in this substudy. Adherence was assessed using the Basel Assessment of Adherence to Immunosuppressive Medications Scale (BAASIS) alongside other sociodemographic, psychosocial, and medical variables.</div></div><div><h3>Results</h3><div>Participants had an average age of 52.3 years (SD = 13.5), with 58.7 % male. According to the BAASIS interview, 22.1 % reported non-adherence, mainly due to timing (13.0 %) and taking (11.7 %) non-adherence, with only 0.5 % ceasing at least one ISM. Factors linked to non-adherence in regression analysis included younger age, male gender, longer post-transplant time, and perceived medication overuse. The effect sizes were small. The informative value is limited by the design and the sample size.</div></div><div><h3>Conclusion</h3><div>In our cross-sectional analysis, nearly a quarter of the participants reported suboptimal adherence, mainly associated with primarily non-modifiable risk factors. Routine adherence assessments and targeted interventions are essential to improving long-term outcomes.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"201 ","pages":"Article 112474"},"PeriodicalIF":3.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145694494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iris Knoop , Annie S.K. Jones , Sam Norton , Nicholas Gall , Rona Moss-Morris
{"title":"Biopsychosocial factors associated with distress in people with suspected postural orthostatic tachycardia syndrome (POTS): A longitudinal regression and correlation study","authors":"Iris Knoop , Annie S.K. Jones , Sam Norton , Nicholas Gall , Rona Moss-Morris","doi":"10.1016/j.jpsychores.2025.112499","DOIUrl":"10.1016/j.jpsychores.2025.112499","url":null,"abstract":"<div><h3>Purpose</h3><div>Postural Orthostatic Tachycardia Syndrome (POTS) is a debilitating condition of the autonomic nervous system with no clear referral, diagnosis, and treatment pathways. Patients experience high levels of symptoms and moderate levels of distress. The purpose of this study was to explore biopsychosocial factors associated with distress in those under investigation for POTS, to identify potential targets for intervention.</div></div><div><h3>Methods</h3><div>A longitudinal, quantitative survey. Participants (<em>n</em> = 149) completed demographic, psychosocial, and symptom questionnaires prior to a diagnostic POTS clinic visit and 6 months follow-up (<em>n</em> = 98). Correlation and regression analyses were used to identify factors associated with distress at baseline (within one month before diagnostic hospital visit) and at 6 months follow up.</div></div><div><h3>Results</h3><div>At baseline, distress levels were moderate and greater symptom focusing, all-or-nothing and avoidance behaviours, threatening views of the illness, emotional reactivity, cardiac anxiety, POTS symptoms, number of specialists seen, lower social support, and younger age were significantly associated with higher levels of baseline distress. The baseline regression model including all demographic, clinical, and psychosocial factors explained 61.2 % of the variance in distress, with the psychosocial variables collectively explaining 55.6 % of this variance (F = 11.06, <em>p</em> < .001). There was no significant difference between distress levels at baseline and follow-up. Psychosocial variables explained 4.7 % of the variance (F = 0.76, <em>p</em> = .665) in changes in distress scores over 6 months. Baseline distress scores accounted for the vast majority of variance in distress at follow-up.</div></div><div><h3>Conclusions</h3><div>This study identified key novel psychosocial factors that were significantly associated with distress which could be potential targets for intervention. Additional factors such as younger age and a higher number of specialists seen were also associated with higher levels of distress, which merits attention when assessing patients' psychological wellbeing this patient group. Distress levels did not significantly change following the specialist consultation and investigation.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"201 ","pages":"Article 112499"},"PeriodicalIF":3.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145776321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Do we still need Engel's biopsychosocial model?","authors":"Fiammetta Cosci","doi":"10.1016/j.jpsychores.2025.112451","DOIUrl":"10.1016/j.jpsychores.2025.112451","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"200 ","pages":"Article 112451"},"PeriodicalIF":3.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145551555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yujing Gu , Honggan Wang , Yun Zhao , Zhaodi Liao , Jun Xie
{"title":"The relationship between fear of disease progression and social isolation in stroke patients: The mediating role of self-perceived burden and self-disclosure","authors":"Yujing Gu , Honggan Wang , Yun Zhao , Zhaodi Liao , Jun Xie","doi":"10.1016/j.jpsychores.2025.112455","DOIUrl":"10.1016/j.jpsychores.2025.112455","url":null,"abstract":"<div><h3>Aim</h3><div>Post-stroke sequelae, such as motor dysfunction, may reduce patients' participation in social activities, thereby increasing their risk of social isolation. Previous studies have linked fear of disease progression with social isolation, yet the underlying mechanisms of this association remain unclear. To develop effective intervention strategies, it is essential to explore the contributing factors related to social isolation in depth.</div></div><div><h3>Methods</h3><div>This study aimed to investigate the mediating roles of self-perceived burden and self-disclosure in the relationship between fear of disease progression and social isolation among stroke patients. A total of 342 inpatients from neurology departments were surveyed using a self-designed demographic questionnaire, the Generalized Alienation Scale (GAS), Fear of Progression Questionnaire-Short Form (FoP-Q-SF), Self-Perceived Burden Scale (SPBS), and Distress Disclosure Index (DDI). A parallel mediation model was constructed, and descriptive statistics, difference tests, Spearman correlation analysis, hierarchical multiple regression, and mediation effect analysis were conducted.</div></div><div><h3>Results</h3><div>Fear of disease progression was positively associated with social isolation (c = 0.275). It was positively related to self-perceived burden (a1 = 0.598) and negatively related to self-disclosure (a2 = −0.412). Both mediators were significantly associated with social isolation (b1 = 0.188; b2 = −0.099). Significant indirect effects were found through self-perceived burden (a1b1 = 0.113) and self-disclosure (a2b2 = 0.041). The direct effect remained significant (c' = 0.121), indicating partial mediation.</div></div><div><h3>Conclusion</h3><div>Self-perceived burden and self-disclosure simultaneously mediate the impact of fear of disease progression on social isolation, offering new insights for healthcare professionals aiming to prevent social isolation among stroke survivors.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"200 ","pages":"Article 112455"},"PeriodicalIF":3.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145566087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonius Schneider , Nele Kornder , Klaus Linde , Alexander Hapfelmeier
{"title":"Sensitivities and specificities of questionnaires and clinical signs and symptoms to predict daily life impairment after SARS-CoV-2 infection varied across different health sectors","authors":"Antonius Schneider , Nele Kornder , Klaus Linde , Alexander Hapfelmeier","doi":"10.1016/j.jpsychores.2025.112439","DOIUrl":"10.1016/j.jpsychores.2025.112439","url":null,"abstract":"<div><h3>Background</h3><div>To investigate the impact of patient selection in different health sectors on sensitivities and specificities of psychosomatic questionnaires and clinical signs and symptoms (CSS) for predicting daily life impairment (DLI) in individuals after SARS-CoV-2 infection.</div></div><div><h3>Methods</h3><div>Secondary data analysis of three independent cross-sectional surveys in general population (<em>n</em> = 2828), fourteen primary care practices (<em>n</em> = 204), and rehabilitation hospital (<em>n</em> = 161). DLI and symptoms were captured using questionnaires. PHQ-15 (Patient Health Questionnaire-15) and SSD-12 (Somatic Symptom Disorder-12), PHQ-2 (Patient Health Questionnaire-2), GAD-2 (Generalized Anxiety Disorder-2), and FAS (Fatigue Assessment Scale) were used to assess somatic symptom disorder (SSD), depression, anxiety and fatigue. Diagnostic indices were calculated to predict DLI.</div></div><div><h3>Results</h3><div>The sensitivities of questionnaires and CSS increased, and specificities decreased from general population to practices and hospital. SSD-12 had a higher diagnostic odds ratio (dOR; 95 % confidence interval) (17.4; 12.6–24.0) in population than in practices (8.4; 3.6–19.7) or hospital (8.1; 1.7–31.7). FAS > 22 had higher dOR (15.0; 11.8–19.1) in population than in practices (5.3; 2.8–9.8) or hospital (4.8; 1.4–16.3). The pattern (population / practice / hospital) was similar in depression (9.2; 7.0–12.0 / 8.0; 3.6–18.1 / 12.2; 1.5–96.2) and anxiety (8.0; 6.0–10.8 / 2.4; 1.0–5.6 / 3.0; 0.6–14.1). Areas under the curves of questionnaires were highest in population, followed by hospital, and consistently lower for practices.</div></div><div><h3>Conclusion</h3><div>There is a large variation in sensitivities and specificities to predict DLI. The extent to which SSD or psychosomatic comorbidity contributes to DLI varied across the health sectors in which patients are diagnosed and treated.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"200 ","pages":"Article 112439"},"PeriodicalIF":3.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145524643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}