Boxuan Pu , Wei Wang , Lubi Lei , Jingkuo Li , Yue Peng , Yanwu Yu , Lihua Zhang , Xin Yuan
{"title":"Association of depressive symptoms and cardiovascular health with mortality among U.S. adults","authors":"Boxuan Pu , Wei Wang , Lubi Lei , Jingkuo Li , Yue Peng , Yanwu Yu , Lihua Zhang , Xin Yuan","doi":"10.1016/j.jpsychores.2024.112032","DOIUrl":"10.1016/j.jpsychores.2024.112032","url":null,"abstract":"<div><h3>Background</h3><div>Depression and cardiovascular health (CVH) are interconnected, and both are independently associated with mortality. However, the joint effects of depressive symptoms and CVH on mortality remain unclear.</div></div><div><h3>Methods</h3><div>By utilizing the National Health and Nutrition Examination Survey (NHANES) 2007–2018, we included 18,679 adults aged ≥20 years without cardiovascular diseases (CVD). The definition of elevated depressive symptoms was based on the Patient Health Questionnaire-9 (PHQ-9) scores≥10. CVH was evaluated by Life's Essential 8 (LE8) and categorized into low (<50), moderate (50–80), or high (≥80). The joint association of depressive symptoms and CVH with mortality was examined utilizing multivariate Cox proportional hazard models.</div></div><div><h3>Results</h3><div>Elevated depressive symptoms were associated with higher mortality risks, and CVH could explain 12.7 % and 13.7 % of the associations between depression and all-cause and non-CVD mortality, respectively. No significant interactions were found between CVH and depressive symptoms on mortality. High CVH attenuated the all-cause mortality risk in patients with elevated depressive symptoms (HR, 0.20; 95 % CI: 0.05–0.89). Compared to participants with elevated depressive symptoms and low CVH, those with no elevated depressive symptoms and high CVH had lower risks of all-cause (HR, 0.26; 95 % CI: 0.16–0.43), CVD (HR, 0.20; 95 % CI: 0.07–0.52), non-CVD mortality (HR, 0.28; 95 % CI 0.16–0.50).</div></div><div><h3>Conclusion</h3><div>Adults with low CVH and elevated depressive symptoms had significantly higher risks of all-cause, CVD, and non-CVD mortality. The finding suggests considering depressive symptoms and CVH jointly in developing targeted strategies to improve survival.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112032"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cognitive behavioural therapy versus other interventions on mental health in people with sensory impairments: A systematic review and meta-analysis","authors":"M. Trott , A. Koblitz , S. Pardhan","doi":"10.1016/j.jpsychores.2024.111998","DOIUrl":"10.1016/j.jpsychores.2024.111998","url":null,"abstract":"<div><h3>Background</h3><div>Sensory impairments can negatively affect people's quality of life and daily functioning, including anxiety and depression symptoms. Cognitive behavioural therapy (CBT) could be an effective intervention to alleviate these, however its effectiveness compared to other interventions have not been examined. The aim of this review was to examine the effectiveness of CBT versus other interventions on anxiety and depression symptoms in people with hearing, visual, and other sensory impairments.</div></div><div><h3>Methods</h3><div>This systematic review and meta-analysis of randomised controlled trials (RCTs) was conducted using a pre-registered protocol (Prospero ID:CRD42023425953). Searches were conducted in across six databases from inception through October 2024. Random-effects meta-analyses were performed.</div></div><div><h3>Results</h3><div>Of 18 included studies, interventions for tinnitus yielded a significant effect favouring intervention on anxiety (Hedge's <em>g</em> = 0.5;95 %CI0.3–0.9) and depression symptoms (Hedge's <em>g</em> = 0.4; 95 %CI 0.1–0.6). Interventions for people with hearing loss not related to tinnitus yielded a significant effect favouring intervention on anxiety symptoms (Hedge's <em>g</em> = 0.6;95 %CI 0.2–1.1), but not in depression symptoms (Hedge's <em>g</em> = 0.3;95 %CI -0.0;0.6). When sub-grouped, no significant differences between CBT and other interventions were found. Interventions for people with vision impairment yielded a non-significant difference in depression symptoms (Hedge's <em>g</em> = 0.4;95 %CI -0.0;0.7), with no studies found examining anxiety symptoms.</div></div><div><h3>Conclusion</h3><div>No significant differences were found when comparing CBT versus other interventions in hearing loss. The effectiveness of CBT for people with visual impairment was less clear due to a small number of studies. Future studies should consider other types of sensory impairments.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 111998"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Colette Naude , David Skvarc , Yao Coitinho Biurra , Lily Blake , Subhadra Evans , Simon Knowles , O. Eric , Chatpakorn Prasertsung , Lahiru Russell , Anna Bassili , Antonina Mikocka-Walus
{"title":"An online mindfulness-based intervention for adults with Inflammatory Bowel Disease & psychological distress: A feasibility randomized controlled trial of the Mind4IBD program","authors":"Colette Naude , David Skvarc , Yao Coitinho Biurra , Lily Blake , Subhadra Evans , Simon Knowles , O. Eric , Chatpakorn Prasertsung , Lahiru Russell , Anna Bassili , Antonina Mikocka-Walus","doi":"10.1016/j.jpsychores.2024.111984","DOIUrl":"10.1016/j.jpsychores.2024.111984","url":null,"abstract":"<div><h3>Objective</h3><div>The bidirectional relationship between disease activity and mental health in inflammatory bowel disease (IBD) has prompted investigations into the efficacy of psychotherapies, such as mindfulness-based interventions (MBI), for improving biopsychosocial outcomes. Therefore, the aim is to examine the feasibility, acceptability, and preliminary efficacy of an online-delivered, self-directed MBI, adapted to individuals with IBD and psychological distress, in comparison to wait-list control (WLC).</div></div><div><h3>Methods</h3><div>50 adults with IBD were randomized to WLC (<em>N</em> = 25) or intervention (N = 25) groups. The intervention (MIND4IBD program) consisted of six, weekly, 15-min videos (with guided meditations). Feasibility was examined through recruitment and retention rates, while acceptability was examined through intervention satisfaction ratings and qualitative feedback. Preliminary efficacy was examined using linear mixed models for group differences in outcomes between baseline and post-intervention.</div></div><div><h3>Results</h3><div>Primary Outcomes. The retention rate for the WLC group was 92 %, while the retention rate for the intervention group was 48 %. However, 16 % of participants allocated to the intervention group never began the intervention, therefore this resulted in a retention rate of 71 % of participants who began the intervention. Acceptability was high with an average intervention satisfaction rating of 83/100. Secondary Outcomes. When compared with the WLC, the MIND4IBD program improved total mindfulness levels (b = 0.29, 95 %CI [0.11,0.47], <em>p</em> = 0.004) with a large effect size (β = 0.54, b = 0.19, 95 %CI [0.04,0.34], <em>p</em> = 0.014). Themes based on participants' intervention feedback included: 1) beginning of journey with mindfulness, 2) the beneficial impact of mindfulness, 3) why adapting the intervention to IBD is important, 4) views on program delivery, and 5) mixed reactions to AI generated presenters.</div></div><div><h3>Conclusion</h3><div>MIND4IBD is feasible and acceptable for individuals with IBD and psychological distress. Participants' total mindfulness levels increased significantly in the intervention group compared to WLC. Most participants provided positive intervention feedback. These findings warrant a full-scale RCT to determine MIND4IBD's efficacy for IBD.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 111984"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elzbieta Klimiec-Moskal, Joanna Pera, Agnieszka Slowik, Tomasz Dziedzic
{"title":"Association of post-stroke delirium with short-term trajectories of cognition","authors":"Elzbieta Klimiec-Moskal, Joanna Pera, Agnieszka Slowik, Tomasz Dziedzic","doi":"10.1016/j.jpsychores.2024.112011","DOIUrl":"10.1016/j.jpsychores.2024.112011","url":null,"abstract":"<div><h3>Background</h3><div>Delirium could increase the risk of cognitive decline. We aimed to determine if changes in cognitive functions shortly after stroke differ between patients with and patients without delirium.</div></div><div><h3>Methods</h3><div>We included patients who participated in the Prospective Observational Polish Study on post-stroke delirium and underwent the Montreal Cognitive Assessment (MoCA) at day 1, day 8 and 3 months after stroke. Delirium was diagnosed using DSM-5 criteria. We used mixed linear regression models to characterize changes in mean adjusted MoCA scores over time.</div></div><div><h3>Results</h3><div>We included 402 patients (mean age: 68.9 <span><math><mo>±</mo></math></span> 13.3 years; mean NIHSS on admission: 6.2 <span><math><mo>±</mo></math></span> 5.5; 48.8 % female). Delirium occurred in 18.9 % of them. Mean adjusted MoCA scores increased from day 1 to day 8 (20.48 vs 23.34, <em>P</em> < 0.001) and then declined from day 8 to month 3 (23.34 vs 22.21, P < 0.001). The rate of change in total MoCA scores from day 1 to day 8 (net effect: 0.65, 95 %CI: −1.19; 2.49, <em>P</em> = 0.489) and from day 8 to month 3 (net effect: -2.43, 95 %CI: −4.84; −0.02, <em>P</em> = 0.147) did not differ between patients with and patients without delirium. Compared with patients without delirium, those with delirium showed a greater improvement in naming, orientation and attention, accompanied by a worsening in memory from day 1 to day 8. They also experienced a greater decline in attention and orientation, along with a greater improvement in memory from day 8 to 3 months.</div></div><div><h3>Conclusions</h3><div>Post-stroke delirium is associated with short-term trajectories of specific cognitive domains, but not with changes in global cognition.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112011"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leah Cha, Amanda K. Montoya, Christine Dunkel Schetter, Jennifer A. Sumner
{"title":"Neighborhood disorder and social cohesion: A longitudinal investigation of links with maternal cardiometabolic risk one year postpartum","authors":"Leah Cha, Amanda K. Montoya, Christine Dunkel Schetter, Jennifer A. Sumner","doi":"10.1016/j.jpsychores.2024.112012","DOIUrl":"10.1016/j.jpsychores.2024.112012","url":null,"abstract":"<div><h3>Objective</h3><div>Neighborhood characteristics can influence cardiometabolic health, including during the perinatal period. However, maternal health research has largely examined the influence of objective neighborhood measures, limiting insights into psychological and social processes. We examined associations of perceived neighborhood disorder and social cohesion with maternal cardiometabolic risk 1 year postpartum and explored potential pathways of psychological distress and physical activity.</div></div><div><h3>Methods</h3><div>A predominantly low-income sample of Black, Latina, and White postpartum women (<em>n</em> = 987) were participants in the Community Child Health Network study. Women reported on neighborhood characteristics at 1 month postpartum and on symptoms of depression, anxiety, and posttraumatic stress disorder and physical activity at 6 months postpartum. Biometrics and biological samples were collected at 1 year postpartum, including blood pressure, height, weight, and dried blood spots for cardiometabolic biomarkers (e.g., C-reactive protein, glycosylated hemoglobin). In this pre-registered study, we used structural equation modeling to estimate latent variables for disorder, social cohesion, distress, physical activity, and cardiometabolic risk. We fit a parallel mediation model to test associations between latent neighborhood factors at 1 month postpartum, distress and physical activity at 6 months postpartum, and cardiometabolic risk at 1 year postpartum.</div></div><div><h3>Results</h3><div>Greater social cohesion, but not disorder, was significantly associated with lower distress and greater physical activity. However, there were no significant associations between disorder or social cohesion with subsequent cardiometabolic risk nor evidence for indirect effects of distress or physical activity.</div></div><div><h3>Conclusion</h3><div>Results suggest that social cohesion may be more pertinent than disorder for health-relevant behavioral mechanisms in postpartum women.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112012"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring the role of psychedelic-assisted therapy in enhancing spirituality and mystical experiences in patients with life-threatening illnesses: A systematic review","authors":"Ana Esteves Ferreira , Paulo Reis-Pina","doi":"10.1016/j.jpsychores.2024.112020","DOIUrl":"10.1016/j.jpsychores.2024.112020","url":null,"abstract":"<div><h3>Introduction</h3><div>Psychedelic-Assisted Therapy (PAT) is gaining traction as a novel approach to addressing the psychological and existential distress experienced by patients.</div></div><div><h3>Objectives</h3><div>This systematic review aimed to investigate the impact of PAT on spirituality, mystical experiences, and spiritual well-being (SpWB) in patients with life-threatening, incurable, or terminal illnesses.</div></div><div><h3>Methods</h3><div>A comprehensive search was conducted across PubMed, Web of Science, and Cochrane databases to identify relevant studies published between 2013 and 2023. The study population comprised patients diagnosed with life-threatening illnesses. Various forms of PAT, encompassing both typical and atypical psychedelic substances, were considered as interventions, with no specific comparators outlined. The primary outcomes of interest included spirituality, mystical experience, and SpWB. Risk of bias assessment was performed using Cochrane's tools.</div></div><div><h3>Results</h3><div>Six studies with a high risk of bias were included in the review, all conducted in the United States of America, involving 140 patients, the majority of whom had cancer (99 %). PAT, especially with psilocybin, demonstrated significant enhancements in spirituality, mystical experiences, and SpWB. Notably, SpWB showed improvements in all studies which assessed this spiritual outcome following PAT. Mystical experiences were correlated with improvements in spirituality in one study.</div></div><div><h3>Conclusions</h3><div>This systematic review underscores the potential of PAT to address unmet spiritual needs and enhance SpWB in patients with life-threatening illnesses. However, further research is needed to elucidate the mechanisms underlying these therapeutic effects. Rigorous evaluation of healthcare practitioners' role in guiding patients through PAT protocols is essential to ensure safe and effective implementation in palliative care settings.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112020"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joel Hoffrén , Juhani Määttä , Jaro Karppinen , Petteri Oura , Eveliina Heikkala
{"title":"Co-occurrence of mental distress and insomnia associates with more severe musculoskeletal pain – Northern Finland Birth Cohort 1966 study","authors":"Joel Hoffrén , Juhani Määttä , Jaro Karppinen , Petteri Oura , Eveliina Heikkala","doi":"10.1016/j.jpsychores.2024.112026","DOIUrl":"10.1016/j.jpsychores.2024.112026","url":null,"abstract":"<div><h3>Objective</h3><div>This cross-sectional study demonstrates the differences in the dimensions of musculoskeletal (MSK) pain between participants with mental distress and/or insomnia among general population with MSK pain within the past 12 months.</div></div><div><h3>Methods</h3><div>Participants of Northern Finland Birth Cohort 1966 (NFBC1966) were studied (<em>n</em> = 4316). They were divided into groups based on their mental distress and insomnia status (co-occurring mental distress and insomnia [CMI], isolated mental distress [M] and insomnia [I], and absence of both [AMI]). The AMI group was used as a reference for the main analyses. The dimensions of MSK pain included frequency, bothersomeness (Numerical Rating Scale [NRS] 0–10), intensity of pain (NRS), and number of pain sites (1–8). Multinomial and general linear regression analyses were used to study the associations, and adjustments were made for sex, education, number of somatic diseases, and physical activity.</div></div><div><h3>Results</h3><div>The CMI group was associated with more severe pain in every dimension when contrasted to all other groups (daily pain adjusted OR 5.08, 95 % CI 3.43–7.51; bothersomeness adjusted β 1.7, 95 % CI 1.5–2.0; intensity adjusted β 1.4, 95 % CI 1.2–1.7; number of pain sites adjusted β 1.2, 95 % CI 1.0–1.4). Compared to AMI, I and M groups also had relationships with all pain dimensions, but with lower magnitude compared to the CMI group.</div></div><div><h3>Conclusions</h3><div>The results suggest that insomnia and mental distress co-exist with more severe MSK pain, and when co-occurring, MSK pain severity tends to increase. Therefore, contemplating insomnia and mental distress are important to consider when comprehensively evaluating MSK pain symptoms.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112026"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kate Faasse , Chiara Gasteiger , Anna Borgmann , Jane Choi , Keith J. Petrie
{"title":"Side effects following administration of open-placebos: A randomized controlled trial","authors":"Kate Faasse , Chiara Gasteiger , Anna Borgmann , Jane Choi , Keith J. Petrie","doi":"10.1016/j.jpsychores.2024.112028","DOIUrl":"10.1016/j.jpsychores.2024.112028","url":null,"abstract":"<div><h3>Objective</h3><div>To assess whether individuals reported more side effects and decreased mood after receiving an open-label placebo compared to a control group that received no treatment.</div></div><div><h3>Methods</h3><div>We randomized participants to receive an open placebo or no treatment. The primary outcome was reported side effects on the Side effect Attribution Scale (SEAS) at 15 min and at 24-h. We also examined negative mood as a secondary outcome and whether psychological variables influenced symptom reporting.</div></div><div><h3>Results</h3><div>At both 15 min and 24-h, participants who took the open-placebo reported a significantly higher number of symptoms (<em>M</em> = 2.03, <em>SE</em> = 0.42) than the control group (<em>M</em> = 1.14, <em>SE</em> = 0.20). Across both time points, participants who took the placebo also reported significantly greater negative mood (<em>M</em> = 6.28, <em>SE</em> = 0.27) than the control group (<em>M</em> = 5.59, <em>SE</em> = 0.16). There was no significant group by time interaction for symptoms or mood (<em>ps</em> > 0.32). Symptom reporting after taking the placebo was not correlated with baseline anxiety, perceived sensitivity to medicines, or modern health worries at either 15 min or 24-h (<em>p</em>s > 0.11).</div></div><div><h3>Conclusions</h3><div>The act of taking a treatment, even knowing it is a placebo, resulted in an increase in symptoms and negative mood reported immediately following pill-taking and 24 h later. These findings have implications for the use of open-label placebos and the prescription of medicines in general, as they suggest the process of taking a medicine may result in increased symptoms and an increase in negative mood.</div></div><div><h3>Trial registration</h3><div>The trial was preregistered at the Australian New Zealand Clinical Trials Registry (12622001570774).</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112028"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Han Cong , Zhibiao Li , Jiahao Zhang , Zeyao Xu , Zhicheng Tang , Yuxin Qian , Juan Wang , Haoliang Wu , Hanxiong Zheng , Zhaohui He , Fucai Tang
{"title":"Adherence to a healthy sleep pattern and the risk of kidney stone disease: A prospective study of UK biobank","authors":"Han Cong , Zhibiao Li , Jiahao Zhang , Zeyao Xu , Zhicheng Tang , Yuxin Qian , Juan Wang , Haoliang Wu , Hanxiong Zheng , Zhaohui He , Fucai Tang","doi":"10.1016/j.jpsychores.2024.111999","DOIUrl":"10.1016/j.jpsychores.2024.111999","url":null,"abstract":"<div><h3>Purpose</h3><div>This research seeks to assess the connection between healthy sleep patterns and the occurrence of kidney stone disease (KSD) by analyzing data obtained from a large-scale cohort study.</div></div><div><h3>Methods</h3><div>We examined 313,870 initial participants without KSD from the UK Biobank. Five healthy sleep factors were assessed: no frequent excessive daytime sleepiness, early chronotype, no snoring, sleeping 7–8 h daily, and never or rarely experiencing insomnia at baseline. A healthy sleep score between 0 and 5 was assigned to participants according to these criteria. We utilized Cox proportional hazards models to calculate hazard ratios (HR) and 95 % confidence intervals (CI) between a healthy sleep score and the occurrence of KSD.</div></div><div><h3>Results</h3><div>During the follow-up period, 3818 new cases of KSD were recorded. After comprehensive adjustments, every 1-point rise in the healthy sleep score was associated with an HR of 0.93 (95 % CI: 0.90–0.96). Additionally, individuals with a healthy sleep score of 5 had a 20 % lower risk of KSD compared to those with scores between 0 and 2.</div></div><div><h3>Conclusions</h3><div>Our study results indicate that adhering to a healthy sleep pattern can reduce the risk of KSD.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 111999"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zehua Wang , Xingjia Mao , Zijian Guo , Hui Huang , Guoyu Che , Tao Li
{"title":"Prevalence and factor associated with depressive symptoms in patients with osteoarthritis: A cross-sectional study","authors":"Zehua Wang , Xingjia Mao , Zijian Guo , Hui Huang , Guoyu Che , Tao Li","doi":"10.1016/j.jpsychores.2024.112018","DOIUrl":"10.1016/j.jpsychores.2024.112018","url":null,"abstract":"<div><h3>Objective</h3><div>Osteoarthritis (OA) is a prevalent degenerative joint condition. Among OA patients, depressive symptoms are the most frequent psychiatric disorder, negatively impacting both prognosis and quality of life. This study analyzed the independent factors associated with the development of depressive symptoms in patients with OA and constructed a nomogram to assess the risk of developing depressive symptoms.</div></div><div><h3>Methods</h3><div>An analysis was conducted on data from 2093 OA patients in the NHANES database, covering 2007 to 2014. A training set and a validation set were randomly assigned to participants in a 7:3 ratio. Variables significantly associated with depressive symptoms in OA patients were identified using the least absolute shrinkage and selection operator (LASSO) and multivariable logistic regression analyses and nomograms were constructed. Its performance and clinical relevance were assessed using receiver operating characteristic (ROC) curves, C indices, calibration curves, and decision curves.</div></div><div><h3>Results</h3><div>Among the 2093 OA patients, 357 were assessed as having depressive symptoms. There are eight independent relevant factors, which are gender, age, poverty-to-income ratio (PIR), race, educational attainment, smoking status, diabetes, and sleep disorder. The AUC values of the training and validation sets were 0.718 (95 %CI: 0.683–0.752) and 0.733 (95 %CI: 0.678–0.788). Calibration and decision curve analyses showed that this nomogram exhibits high accuracy, good discrimination, and potential clinical benefits on both training and validation sets.</div></div><div><h3>Conclusions</h3><div>We screened to obtain factors associated with depressive symptoms in patients with OA. Dynamic nomograms enable the combination of individual relevant factors for better assessing and managing high-risk OA groups.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112018"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}