Journal of Renal Nutrition最新文献

{"title":"July Meeting Announcements","authors":"Mary Kay Hensley MS, RDN, FAND, FNKF","doi":"10.1053/j.jrn.2026.06.001","DOIUrl":"10.1053/j.jrn.2026.06.001","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 4","pages":"Page 650"},"PeriodicalIF":4.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148647214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional Quality of Plant-Based Products in the Chilean Market: Implications for Dietary Management of Chronic Kidney Disease","authors":"Francisca Peña-D’Ardaillon MSc,&nbsp;Pía Figueroa BSc,&nbsp;Lara Thome BSc,&nbsp;Ariel Guillof BSc,&nbsp;Esperanza Parada BSc,&nbsp;Ignacio Soto BSc,&nbsp;Agustina Palma BSc,&nbsp;Jessica Moya MSc,&nbsp;Elizabeth Sánchez MSc,&nbsp;Marcell Leonario-Rodriguez MSc","doi":"10.1053/j.jrn.2025.11.002","DOIUrl":"10.1053/j.jrn.2025.11.002","url":null,"abstract":"<div><h3>Objective</h3><div>Analyze the nutritional quality of the plant-based food products available in Chilean market, considering the dietary needs of the population with chronic kidney disease.</div></div><div><h3>Methods</h3><div>An analytical study evaluated plant-based products from two major Chilean’s retail holdings, representing over 75% of the national market. In the second half of 2024, products were selected from updated online catalogs based on plant-based indicators. The Chilean front-of-pack warning system was applied using established thresholds for energy, sodium, sugars, and saturated fats for both solids and liquids. Comparative analyses were also performed between meat and dairy substitutes and their conventional counterparts using nutritional data pertinent to the renal population. Data were analyzed with GraphPad Prism v.10.0 using descriptive and inferential statistics.</div></div><div><h3>Results</h3><div>Among 378 items classified as meat substitutes, dairy substitutes, bakery items, cookies and sweets, ice cream and desserts, and ready-to-eat products. Nutritional analysis revealed significant differences among groups (<em>P</em> &lt; .0001). Compared to animal-derived products, meat substitutes had lower protein but differed significantly in saturated fats, sodium, carbohydrates, and polyunsaturated fats, and dairy substitutes were markedly different from conventional dairy across nearly all nutrients (<em>P</em> &lt; .0001). Additionally, meat substitutes were significantly associated with sodium additives, whereas dairy substitutes were more likely to contain phosphorus and potassium additives.</div></div><div><h3>Conclusions</h3><div>Plant-based products available on the Chilean market do not represent an appropriate alternative for prescription in populations with chronic kidney disease. Although meat and dairy substitutes exhibit lower protein content, they contain critical additives such as sodium, phosphorus, and potassium.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 4","pages":"Pages 583-593"},"PeriodicalIF":4.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145592742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Home-Based Precision Multicomponent Exercise and Daily Steps in Non–Dialysis-Dependent Stages 3-5 Chronic Kidney Disease: A Randomized Controlled Trial","authors":"Fan Zhang MD,&nbsp;Liuyan Huang MD,&nbsp;Ying Jia BD,&nbsp;Rui Zhou BD,&nbsp;Jing Liao BD,&nbsp;Yibo Ren BD,&nbsp;Daijuan Xu BD,&nbsp;Weihong Zhang BD,&nbsp;Tianyi Cheng MD,&nbsp;Jiao Li PhD,&nbsp;Zilin Ma PhD,&nbsp;Yifei Zhong PhD","doi":"10.1053/j.jrn.2026.02.009","DOIUrl":"10.1053/j.jrn.2026.02.009","url":null,"abstract":"<div><div>Chronic kidney disease (CKD) is associated with reduced physical activity, impaired functional capacity, and diminished health-related quality of life (HRQoL). Evidence supports exercise benefits, but scalable delivery models embedded in nephrology care remain limited. We conducted a prospective, parallel-group, randomized clinical trial comparing a 24-week, home-based, multicomponent exercise program delivered by a physician-nurse team with standard care in adult patients with nondialysis-dependent CKD Stages 3-5. The intervention emphasized progressive walking, resistance training using elastic bands and bodyweight, and balance/mobility drills, with nurse-led check-ins (weekly through 12 weeks, then biweekly to 24 weeks). The primary outcome was daily steps assessed by accelerometry, and the secondary outcomes included handgrip strength, gait speed, five-times sit-to-stand, and six-minute walk distance (6MWD), plus HRQoL. Prespecified mediator analyses evaluated whether 24-week changes in functional metrics mediated the effect of group assignment on HRQoL change. Analyses followed intention-to-treat with mixed-effects models adjusted for demographic and clinical covariates. Among the 140 randomized participants, 117 (intervention 56; control 61) contributed to intention-to-treat analyses. Compared with usual care, the 24 week home-based, multicomponent exercise program produced greater increases in daily steps at 12 weeks (adjusted mean difference [aMD] 331.45 steps/day; 95% confidence interval: 205.34-457.56; <em>P</em> &lt; .001) and 24 weeks (aMD 793.78; 95% confidence interval: 668. 77-918.79; <em>P</em> &lt; .001). Physical function improved at 12 and 24 weeks, respectively: handgrip strength (aMD 1.93 kg and 1.36 kg; both <em>P</em> &lt; .001), gait speed (0.09 m/s and 0.24 m/s; both <em>P</em> &lt; .001), sit to stand (−1.92 s and −2.49 s; both <em>P</em> &lt; .001), and 6MWD (22.12 m and 68.85 m; both <em>P</em> &lt; .001). HRQoL improved, with mediation analyses indicating that gains in 6MWD accounted for approximately 21.0% of the effect on score. No life threatening adverse events occurred; reported events were mild and self limiting. Home-based, multicomponent exercise program integrated into routine nephrology workflows and delivered by a physician-nurse team improved physical activity, physical function, and HRQoL in patients with nondialysis-dependent CKD Stages 3-5.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 4","pages":"Pages 571-582"},"PeriodicalIF":4.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147501608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplemental Protein to Decrease Inflammation in Maintenance Hemodialysis Patients: Advantage Whey?","authors":"Giacomo Garibotto MD,&nbsp;Linda W. Moore PhD, RDN","doi":"10.1053/j.jrn.2026.06.003","DOIUrl":"10.1053/j.jrn.2026.06.003","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 4","pages":"Pages 537-539"},"PeriodicalIF":4.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148240800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interaction Between Magnesium Intake and Serum 25-Hydroxyvitamin D Levels in Modulating the Likelihood of Chronic Kidney Disease: Evidence From the NHANES 2009-2014","authors":"Jian Lu MD,&nbsp;Xinru Shang MS,&nbsp;Zekai Deng MB,&nbsp;Shiming Jiang MD,&nbsp;Shunwei Wang MB,&nbsp;Wenge Li MD","doi":"10.1053/j.jrn.2025.12.008","DOIUrl":"10.1053/j.jrn.2025.12.008","url":null,"abstract":"<div><h3>Objective(s)</h3><div>While vitamin D is known to facilitate intestinal magnesium (Mg) absorption, the combined effect of these nutrients on the prevalence of chronic kidney disease (CKD) remains unclear. This study investigated how serum 25-hydroxyvitamin D [25(OH)D] levels modify the association between dietary Mg intake and CKD.</div></div><div><h3>Methods</h3><div>Cross-sectional subject evaluations were performed using data from the 2009-2014 National Health and Nutrition Examination Surveys. The assessment of dietary Mg intake conducted through a 24-hour dietary recall, while the determination of 25(OH)D serum levels was accomplished using a radioimmunoassay kit. CKD was defined based on the presence of albuminuria and estimated glomerular filtration rate. A probability sample (n = 12,435) aged ≥20 years was drawn from the noninstitutionalized civilian population of the United States. Multiple regression analysis was employed to ascertain the independent association between total Mg intake, serum 25(OH)D, and CKD, while controlling for age, sex, race/ethnicity, body mass index, and energy intake. Given the intricate nature of the survey design, all analyses were weighted.</div></div><div><h3>Results</h3><div>A notable correlation was observed between increased Mg consumption and a reduced likelihood of CKD (odds ratio [OR] = 0.836, 95% confidence interval [CI]: 0.729-0.959, <em>P</em> = .014). The relationship between Mg intake and the prevalence of CKD was found to differ based on the levels of 25(OH)D. Specifically, among individuals with 25(OH)D levels equal to or below 50 nmol/L, no significant association was observed (OR: 1.054, 95% CI: 0.730-1.522, <em>P</em> = .764). In contrast, among those with 25(OH)D levels greater than 50 nmol/L, higher Mg intake was associated with lower odds of CKD (OR: 0.796, 95% CI: 0.685-0.926, <em>P</em> = .006). A significant interaction was observed (interaction <em>P</em> value = .002). Notably, among vitamin D–sufficient participants with moderate to severe CKD (stages G3-G5), each unit increase in Mg z-score was associated with 33% lower odds of CKD (OR = 0.67, 95% CI: 0.49-0.92), with a clear dose-response trend (<em>P</em> for trend = .023).</div></div><div><h3>Conclusion(s)</h3><div>The renal protective effect of Mg consumption appears dependent on adequate vitamin D status, particularly in advanced CKD, suggesting combined nutritional supplementation strategies may warrant investigation in CKD prevention.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 4","pages":"Pages 602-612"},"PeriodicalIF":4.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146004845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: Assessment of Nutritional Intake in Patients With Kidney Failure Treated by Hemodialysis on Dialysis and Nondialysis Days","authors":"I-Hua Huang RN,&nbsp;Wei-Chih Kan MD,&nbsp;Chih-Chung Shiao MD","doi":"10.1053/j.jrn.2025.09.008","DOIUrl":"10.1053/j.jrn.2025.09.008","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 4","pages":"Pages 642-644"},"PeriodicalIF":4.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146196358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Iron Status With Global and Domain-Specific Cognitive Function in Patients With Non–Dialysis Chronic Kidney Disease","authors":"Ting-Yun Lin MD,&nbsp;Szu-Chun Hung MD","doi":"10.1053/j.jrn.2026.02.004","DOIUrl":"10.1053/j.jrn.2026.02.004","url":null,"abstract":"<div><div>Cognitive impairment is prevalent in patients with chronic kidney disease (CKD) and may be exacerbated by iron deficiency through impaired oxygen delivery and disrupted neuronal metabolism. However, no prior study has specifically examined the role of iron status in cognitive function among patients with nondialysis CKD. This study aimed to investigate the associations of iron status markers (serum iron, transferrin saturation [TSAT], and ferritin) as well as hemoglobin with cognitive performance in CKD stages 3-5. We conducted a cross-sectional study of 147 patients with nondialysis CKD [median age 66.0 (57.0-72.0) years; median estimated glomerular filtration rate 23.0 (13.5-33.2) mL/min/1.73 m²]. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE). Mild cognitive impairment (MCI) was defined as MoCA scores ≤23 or MMSE scores ≤26. Associations between iron markers and cognitive scores were analyzed using linear and logistic regression models, adjusted for age, sex, education, comorbidities (diabetes, hypertension, and cardiovascular disease), physical activity, estimated glomerular filtration rate, use of erythropoiesis-stimulating agents, Z-drugs, and hemoglobin. Patients with MCI were older, had lower education levels, and exhibited reduced serum iron, TSAT, and physical activity. Higher serum iron and TSAT levels were independently associated with better MoCA and MMSE scores and lower odds of MCI. Domain-specific analyses revealed that serum iron and TSAT were positively associated with MoCA attention and abstraction domains, and MMSE orientation and attention/calculation domains. No consistent associations were observed for ferritin, and hemoglobin was not significantly associated with cognitive outcomes after adjustment. In nondialysis CKD stages 3–5, higher serum iron and TSAT levels were independently associated with better global and domain-specific cognitive function, regardless of hemoglobin status. These findings suggest a potential role for iron status in modulating cognitive health in CKD, meriting further longitudinal and interventional studies.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 4","pages":"Pages 550-559"},"PeriodicalIF":4.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Letter to the Editor: “Computed Tomography–Based Abdominal Myosteatosis Indicators and Handgrip Strength in Hemodialyzed Patients”","authors":"Takahiro Yajima MD,&nbsp;Maiko Arao MD","doi":"10.1053/j.jrn.2026.02.005","DOIUrl":"10.1053/j.jrn.2026.02.005","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 4","pages":"Pages 647-649"},"PeriodicalIF":4.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Sarcopenic Obesity and Worsening Physical Performance in Patients Undergoing Hemodialysis: The REPnet-HD Study","authors":"Sho Kojima PT, PhD,&nbsp;Naoto Usui PT, PhD,&nbsp;Yuki Nishiyama PT, MSc,&nbsp;Nobuhito Shinozaki PT,&nbsp;Nobuyuki Shirai PT, PhD,&nbsp;Daisuke Okamura PT,&nbsp;Yoichi Sato PT, PhD,&nbsp;Syun Hirukawa PT,&nbsp;Takahumi Noji PT,&nbsp;Toshiaki Kasai PT,&nbsp;Harunori Takahashi PT, MSc,&nbsp;Yoji Yamada PT, PhD,&nbsp;Akihiro Sakuyama PT, PhD,&nbsp;Yoshifumi Abe PT, PhD,&nbsp;Masakazu Saitoh PT, PhD","doi":"10.1053/j.jrn.2026.02.007","DOIUrl":"10.1053/j.jrn.2026.02.007","url":null,"abstract":"<div><h3>Objective</h3><div>Sarcopenic obesity, defined by excess fat mass with concurrent sarcopenia, is an emerging public health concern. In patients undergoing hemodialysis, reduced physical performance is associated with poor prognosis. This study aimed to investigate association between sarcopenic obesity and worsening physical performance over 1 year in patients undergoing hemodialysis.</div></div><div><h3>Design and Methods</h3><div>In this multicenter prospective cohort study, patients undergoing hemodialysis from 12 facilities were evaluated. Physical performance was measured using the Short Physical Performance Battery at baseline and after 1 year. Sarcopenic obesity was defined by the presence of both low muscle mass and strength (sarcopenia) and high body fat mass (obesity). Patients were categorized into four groups: no sarcopenia or obesity, obesity alone, sarcopenia alone, and sarcopenic obesity. Decline in physical performance was defined as a decrease in Short Physical Performance Battery score by ≥ 1 point, and associations were examined using multivariate logistic regression.</div></div><div><h3>Results</h3><div>Among 295 patients (median age 70 years; 123 females), the prevalence of no sarcopenia or obesity, obesity, sarcopenia, and sarcopenic obesity was 47%, 20%, 17%, and 16%, respectively. Univariate analysis showed that both sarcopenic obesity (odds ratio [OR]: 3.67, 95% confidence interval [CI]: 1.8-7.47, <em>P</em> &lt; .001) and sarcopenia (OR: 2.12, 95% CI: 1.03-4.36, <em>P</em> = .04) were significantly associated with worsening performance. In multivariate analysis, only sarcopenic obesity remained significant (OR: 2.76, 95% CI: 1.06-7.19, <em>P</em> = .04).</div></div><div><h3>Conclusion</h3><div>Sarcopenic obesity was associated with decreased physical performance over 1 year in patients undergoing hemodialysis and may contribute to future physical dysfunction.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 4","pages":"Pages 613-622"},"PeriodicalIF":4.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147492289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severity of Cognitive Dysfunction Associates With Sarcopenia in Patients on Hemodialysis: Findings From the SARC-HD Study","authors":"Marvery P. Duarte PhD,&nbsp;Otávio T. Nóbrega PhD,&nbsp;Ana C. Grangeiro BSc,&nbsp;Danielle C. Moreira BSc,&nbsp;Jéssica G. Roure MSc,&nbsp;Fábio A. Vieira MSc,&nbsp;Maryanne Z.C. Silva PhD,&nbsp;Dario R. Mondini BSc,&nbsp;Henrique S. Disessa MSc,&nbsp;Angélica N. Adamoli PhD,&nbsp;Daiana C. Bündchen PhD,&nbsp;Bruna R.M. Sant'Helena PhD,&nbsp;Rodrigo R. Krug PhD,&nbsp;Maristela Bohlke MD, PhD,&nbsp;Ricardo M. Lima PhD,&nbsp;Marco C. Uchida PhD,&nbsp;Antônio J. Inda-Filho MD, PhD,&nbsp;Maycon M. Reboredo PhD,&nbsp;Moises Wesley MSc,&nbsp;Heitor S. Ribeiro PhD,&nbsp;Barbara P. Vogt","doi":"10.1053/j.jrn.2026.03.002","DOIUrl":"10.1053/j.jrn.2026.03.002","url":null,"abstract":"<div><h3>Objective</h3><div>This study investigated the association between cognitive dysfunction and sarcopenia in patients on hemodialysis.</div></div><div><h3>Methods</h3><div>This is a cross-sectional analysis of the SARC-HD study. Cognitive function was assessed using the Mini-Mental State Examination, adjusted for literacy level. Patients were categorized with normal cognition, mild-to-moderate dysfunction, or severe cognitive dysfunction. Sarcopenia was diagnosed and staged according to the adapted European Working Group on Sarcopenia in Older People criteria, assessing handgrip strength or sit-to-stand test, calf circumference, and usual gait speed. For regression analyses (adjusted for clinically relevant confounders), confirmed and severe sarcopenia stages were combined into a binary outcome.</div></div><div><h3>Results</h3><div>A total of 946 patients were analyzed (48% ≥ 60 years, 61% male, and median dialysis vintage of 33 months). Mild-to-moderate and severe cognitive dysfunctions were observed in 38% and 18% of the cohort, respectively. Patients with cognitive dysfunction exhibited poorer physical function and lower calf circumference, higher prevalence of all sarcopenia traits, and higher rate of severe sarcopenia. In the adjusted logistic regression, only severe cognitive dysfunction was significantly associated with sarcopenia, showing 87% higher odds (adjusted odds ratio = 1.87, 95% confidence interval: 1.11-3.16) compared to the normal cognition group. In the fully adjusted model including malnutrition, this association did not remain significant (adjusted odds ratio= 1.55, 95% confidence interval: 0.86-2.82).</div></div><div><h3>Conclusions</h3><div>In patients on hemodialysis, severe cognitive dysfunction was associated with sarcopenia, although this may be mediated by malnutrition. These findings underscore the need for integrated assessment strategies targeting both cognitive and physical declines in this population.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 4","pages":"Pages 623-630"},"PeriodicalIF":4.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147501598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}