Journal of Renal Nutrition最新文献

{"title":"Association of protein intake with discordance between cystatin C- and creatinine-based eGFR in community-dwelling Japanese adults.","authors":"Keiko Kabasawa, Ribeka Takachi, Michihiro Hosojima, Tomoyo Komata, Kazutoshi Nakamura, Norie Sawada, Shoichiro Tsugane, Yumi Ito, Junta Tanaka, Ichiei Narita, Kunihiro Matsushita","doi":"10.1053/j.jrn.2024.12.007","DOIUrl":"https://doi.org/10.1053/j.jrn.2024.12.007","url":null,"abstract":"<p><strong>Objective: </strong>Recent studies have reported the prognostic implications of the discordance between creatinine-based and cystatin C-based estimated glomerular filtration rates (eGFR_cr and eGFR_cys, respectively); however, the associations of protein intake with the eGFR discordance have not been investigated. The present study investigated whether protein intake was associated with the discordance between eGFR_cr and eGFR_cys.</p><p><strong>Design and methods: </strong>We cross-sectionally analyzed data from a Japanese community-based cohort including 6,143 participants (50.7% women; age range, 40-97 years). Protein intake was estimated by food groups derived from a validated food frequency questionnaire. As a measure of discordance, we modeled the ratio of eGFR_cys and eGFR_cr (eGFR_cys divided by eGFR_cr) continuously in multivariable linear regression models and categorically (<0.8, 0.8-1.1, and ≥1.2) in multinomial logistic regression models. We analyzed men and women separately given their distinct dietary patterns.</p><p><strong>Results: </strong>The mean eGFR ratio was 1.15 in men and 1.19 in women. In multivariable linear regression analysis, total protein was positively associated with the eGFR ratio in men (regression coefficient, 0.005 [95% CI, 0.003, 0.007]). When animal and plant proteins were analyzed separately, a significant positive association was seen for animal protein only in men (0.005 [0.003, 0.007]). The results were similar when we modeled protein intake categorically by multinomial logistic regression.</p><p><strong>Conclusion: </strong>This study suggests intake of dietary protein, especially animal protein in men, as a determinant of eGFR discordance. Future studies exploring eGFR discordance and health outcomes should consider simultaneously assessing dietary protein intake.</p>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypomagnesemia is a risk factor for acute kidney injury in patients admitted with ST-segment elevation myocardial infarction: A retrospective observational study.","authors":"Youkai Jin, Qingcheng Lin, Dingzhou Wang, Mengge Gong, Weijian Huang, Peiren Shan, Dongjie Liang","doi":"10.1053/j.jrn.2024.12.006","DOIUrl":"https://doi.org/10.1053/j.jrn.2024.12.006","url":null,"abstract":"<p><strong>Background: </strong>Acute kidney injury (AKI) is prevalent in patients hospitalized with ST-segment elevation myocardial infarction (STEMI) and is correlated with worse cardiovascular outcomes. Hypomagnesemia has been found to be associated with an elevated risk of AKI in various patient populations. Nonetheless, the relationship between hypomagnesemia and AKI incidence in patients with STEMI has not been fully elucidated. The study aims to investigate the association between admission serum magnesium levels and the development of AKI in patients with STEMI.</p><p><strong>Materials and methods: </strong>A total of 1,219 patients with STEMI were retrospectively included in this study and assigned to the hypomagnesemia and non-hypomagnesemia groups. Hypomagnesemia was defined as a serum magnesium level < 0.75 mmol/L. The primary study outcome was AKI Incidence during hospitalization. Univariate and multivariate logistic regression analyses were conducted to assess the association between serum magnesium levels and AKI incidence.</p><p><strong>Results: </strong>Overall, 163 patients (13.4%) met the hypomagnesemia criteria, and 256 (21.0%) patients developed AKI. The AKI incidence was significantly higher in the hypomagnesemia group compared to the non-hypomagnesemia group (31.9% vs. 19.3%; P <0.001). Multivariate logistic analysis, adjusted for demographic characteristics and other confounding variables, revealed that hypomagnesemia is a risk factor for AKI (OR: 2.41, 95% CI: 1.61-3.62; P< 0.001).</p><p><strong>Conclusions: </strong>Hypomagnesemia at admission is an independent predictor for AKI occurrence in patients with acute STEMI. Therefore, interventions targeting serum magnesium levels to mitigate AKI risk may warrant clinical consideration.</p>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saltiness perception and sodium intake in patients with chronic kidney disease.","authors":"Elisa Russo, Giacomo Garibotto, Linda W Moore","doi":"10.1053/j.jrn.2024.12.005","DOIUrl":"https://doi.org/10.1053/j.jrn.2024.12.005","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of ChatGPT to Support Nutritional Recommendations for Dialysis Patients: Comment.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.1053/j.jrn.2024.11.006","DOIUrl":"https://doi.org/10.1053/j.jrn.2024.11.006","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is the \"Nutritional Risk Index for Japanese Hemodialysis\" validated as a nutritional and prognostic indicator?","authors":"Katsuhito Mori, Yosuke Yamamoto, Norio Hanafusa, Suguru Yamamoto, Shingo Fukuma, Yoshihiro Onishi, Masanori Emoto, Masaaki Inaba","doi":"10.1053/j.jrn.2024.12.004","DOIUrl":"https://doi.org/10.1053/j.jrn.2024.12.004","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is the \"Nutritional Risk Index for Japanese Hemodialysis\" validated as a nutritional and prognostic indicator?","authors":"Takahiro Yajima","doi":"10.1053/j.jrn.2024.12.003","DOIUrl":"https://doi.org/10.1053/j.jrn.2024.12.003","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author's Reply to Letter to the Editor regarding the paper \"Nutritional status of patients starting on peritoneal dialysis: Comparison between planned and unplanned dialysis initiation\".","authors":"Maryanne Zilli Canedo Silva, Carla Maria Avesani, Jacqueline Costa Teixeira Caramori","doi":"10.1053/j.jrn.2024.11.008","DOIUrl":"https://doi.org/10.1053/j.jrn.2024.11.008","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary: Application of ChatGPT to Support Nutritional Recommendations for Dialysis Patients - A Qualitative and Quantitative Evaluation.","authors":"Lin-Chun Wang, Hanjie Zhang","doi":"10.1053/j.jrn.2024.11.007","DOIUrl":"https://doi.org/10.1053/j.jrn.2024.11.007","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Higher renal net acid, but not higher phosphate excretion during growth associates with lower adult circulating uromodulin\".","authors":"Seyedeh-Masomeh Derakhshandeh-Rishehri, Luciana Peixoto Franco, Hermann Kalhoff, Stefan A Wudy, Thomas Remer","doi":"10.1053/j.jrn.2024.12.002","DOIUrl":"https://doi.org/10.1053/j.jrn.2024.12.002","url":null,"abstract":"<p><strong>Objective: </strong>Uromodulin is the most abundant urinary protein in healthy subjects which under physiological conditions protects against kidney stone formation. Acid-base imbalances, especially states with acidic urine, increase the risk for uric acid and oxalate stones, but lower it for phosphate-containing stones. Whether habitual high acid loads and high dietary phosphorus intake (P-In) themselves may influence plasma uromodulin concentrations in the long-term is not known.</p><p><strong>Methods: </strong>we prospectively examined biomarker-based the associations of P-In and endogenous acid loads of 3-17 years old healthy participants (n=358) of the DONALD study (Dortmund, Germany) with their circulating uromodulin levels later in adulthood. Urinary phosphate excretion (PO₄-Ex), net acid excretion (NAE), potential renal acid load (uPRAL), and pH were analyzed in 24-hour urine samples repeatedly collected during growth. Circulating uromodulin was analyzed in adult fasting blood samples. Individual means of age- and sex-stratified standard-deviation-scores of growth- and nutritional biomarker-related parameters were calculated. Multi-linear regression models adjusted for anthropometric, renal, and blood parameters were conducted to examine the prospective relationships of pre-adulthood urinary biomarkers with adult circulating uromodulin.</p><p><strong>Results: </strong>Uromodulin associated inversely with NAE (P_for-trend<0.03) and positively with urinary pH (P_for-trend=0.05; lowest pH-quintile vs. highest quintile: P=0.03), but not significantly with uPRAL and PO₄-Ex during growth.</p><p><strong>Conclusion: </strong>the known increased urolithiasis risk associated with high endogenous acid production may be further augmented by a high NAE-related reduction of the stone-formation inhibitor uromodulin. Despite not observing a significant association with uPRAL, the potential of habitual low-PRAL diets to raise uromodulin needs to be further studied.</p>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Nutritional Supplementation Combined with Exercise Training on Frailty, Physical Function, and Quality of Life in Chronic Kidney Disease: A Systematic Review and Meta-Analysis.","authors":"Fan Zhang, Hui Wang, Bai Yan, Liuyan Huang, Huachun Zhang","doi":"10.1053/j.jrn.2024.11.009","DOIUrl":"https://doi.org/10.1053/j.jrn.2024.11.009","url":null,"abstract":"<p><strong>Objective: </strong>A combined intervention strategy of nutritional supplementation and exercise training has the potential to support the treatment of frailty and improve health outcomes in patients with chronic kidney disease (CKD). This study aimed to evaluate the effectiveness of nutritional supplementation combined with an exercise training intervention on frailty characteristics, physical function, and health-related quality of life in patients with CKD.</p><p><strong>Design and methods: </strong>PubMed, Embase, Web of Science, and Scopus were searched from inception to October 22, 2022, and the search was updated in May 2023. A randomized controlled trial (RCT) compared nutritional supplementation combined with exercise training to usual care/single nutritional supplementation or exercise training to assess the effect on Fried-based frailty characteristics and physical function in CKD patients was included. Two authors independently selected literature, extracted data, and assessed the risk of bias using the Cochrane risk of bias tool 2. The outcome was analyzed using a random-effect model using the Hartung-Knapp-Sidik-Jonkman method or a fixed-effect model using restricted maximum likelihood. Using the \"leave-one-out\" method for sensitivity analysis.</p><p><strong>Results: </strong>Seven articles (nine trials with a total of 324 patients) were included. Meta-analysis showed that nutritional supplementation combined with an exercise training intervention may improve frailty characteristics of dialysis patients, such as walking speed (mean difference (MD): 0.09 m/s, 95% (confidence interval) CI 0.02 to 0.16), and physical functioning, such as cardiorespiratory fitness (standardized mean difference (SMD): 0.56, 95% CI 0.20 to 0.93), and lower extremity mobility as assessed by the timed up and go test (MD: -1.11 s, 95% CI -1.79 to -0.43). However, the effect of combined interventions on other indicators such as body weight (MD: 1.28 kg, 95% CI -2.06 to 4.62), fatigue (SMD: 0.57, 95% CI -1.44 to 0.30), and health-related quality of life is uncertain. These results should be interpreted with caution because of the heterogeneity of the included studies and the relatively small sample size.</p><p><strong>Conclusion: </strong>An intervention strategy of nutritional supplementation combined with exercise training may help improve frailty and physical functioning in CKD patients, particularly walking speed, cardiorespiratory fitness, and lower extremity mobility. Future studies should focus on larger sample sizes and longer-term follow-up to confirm these preliminary findings and explore potential effects on other health indicators.</p>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}