Journal of Renal Nutrition最新文献

{"title":"The discordance between creatinine- and cystatin C-based estimated GFR: a matter of protein intake?","authors":"Michela Saio, Giacomo Garibotto, Linda W Moore","doi":"10.1053/j.jrn.2025.03.007","DOIUrl":"https://doi.org/10.1053/j.jrn.2025.03.007","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143774683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between frailty, as assessed using the Kihon Checklist, and falls in hemodialysis patients: a multicenter prospective cohort study.","authors":"Nobuyuki Shirai, Naoto Usui, Daisuke Okamura, Yoichi Sato, Sho Kojima, Kenta Mikami, Mizuki Nagashima, Yu Shimano, Nobuhito Shinozaki, Syun Hirukawa, Akihiro Sakuyama, Yoji Yamada, Masakazu Saitoh","doi":"10.1053/j.jrn.2025.03.006","DOIUrl":"https://doi.org/10.1053/j.jrn.2025.03.006","url":null,"abstract":"<p><strong>Objectives: </strong>Hemodialysis (HD) patients are at a high risk of frailty, falls, and fractures. The Kihon checklist (KCL) consists of physical function, cognitive function, oral function, nutritional status, depressed mood, activities of daily living, and social participation. This study aimed to clarify the association between falls in HD patients and frailty as assessed using the KCL, as well as scores and each domain.</p><p><strong>Methods: </strong>A multicenter prospective cohort study was conducted across nine facilities. Frailty was assessed using the KCL. Falls were then monitored for one year. Participants were classified into three groups based on their KCL scores: robust, pre-frailty, and frailty. In the logistic regression analysis, the dependent variables were falls, severe falls, or fractures, whereas the independent variables were group classification, KCL score, or each domain.</p><p><strong>Results: </strong>A total of 403 HD patients (70.0 [60.0-76.0] years, 170 [42.1%] women) were analyzed. During the 1-year follow-up period, 117 (29.0%) patients experienced falls. Pre-frailty (OR 3.00, 95%CI 1.17-7.71, p < 0.001) and frailty (OR 6.79, 95%CI 2.69-17.16, p < 0.001) were independently associated with falls compared with robust patients. Additionally, the KCL score was associated with severe falls (OR 1.15, 95%CI 1.06 - 1.25, p = 0.001) and fracture (OR 1.13, 95%CI 1.01-1.28, p = 0.04). By KCL domain, physical function (OR 3.46, 95%CI 2.06-5.83, p < 0.001) and cognitive function (OR 1.74, 95%CI 1.09-2.77, p = 0.02) were independently associated with falls.</p><p><strong>Conclusions: </strong>The KCL may be a useful screening tool for estimating fall and fracture risk in this population.</p>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on: The Effect of Antihypertensive Therapy on Skeletal Muscle Mass and Bone Mineral Density in Patients With End-Stage Kidney Disease.","authors":"Aqsa Sabir, Alaita Fatima Bakhtiari","doi":"10.1053/j.jrn.2025.01.009","DOIUrl":"10.1053/j.jrn.2025.01.009","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability Between Sarcopenia Diagnosis by EWGSOP 1 and EWGSOP 2 Criteria and Association With Clinical Parameters in Maintenance Hemodialysis Patients.","authors":"Laura Tavares Guimarães, Maryanne Zilli Canedo da Silva, Nayrana do Carmo Soares Reis, Jacqueline Costa Teixeira Caramori, Barbara Perez Vogt","doi":"10.1053/j.jrn.2025.03.005","DOIUrl":"10.1053/j.jrn.2025.03.005","url":null,"abstract":"<p><strong>Objectives: </strong>To analyze the reliability between the sarcopenia criteria proposed by the European Working Group on Sarcopenia in Older People (EWGSOP) 1 and 2 and to verify the association of clinical parameters with sarcopenia diagnosis in patients on maintenance hemodialysis.</p><p><strong>Methods: </strong>Cross-sectional analysis including adult patients on maintenance hemodialysis. The assessment of lean mass was performed by dual-energy X-ray absorptiometry, and the appendicular lean mass index was calculated. The assessment of muscle strength was performed using a handgrip dynamometer. The cutoff values considered for sarcopenia diagnosis were proposed by the EWGSOP 1 and EWGSOP 2 criteria.</p><p><strong>Results: </strong>124 patients were included. The frequency of sarcopenia diagnosis was higher according to EWGSOP 1 (25.8%) than according to EWGSOP 2 (12.9%). The frequency of sarcopenia diagnoses diminished in both sexes. The reliability between the two criteria was moderate (κ = 0.597; P < .001), and 87.1% of patients were classified equally by both criteria. In EWGSOP 1, the presence of diabetes and serum iron was significantly higher in the group with sarcopenia, and in EWGSOP 2 there was no such difference.</p><p><strong>Conclusion: </strong>The frequency of sarcopenia diagnosis in patients on hemodialysis was higher by EWGSOP 1 compared to EWGSOP 2, and the reliability between the criteria was moderate. Sarcopenia diagnosed by EWGSOP 1 was associated with diabetes and serum iron, which are factors that may be associated with sarcopenia pathogenesis. EWGSOP 2 was not associated with the clinical parameters assessed.</p>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response Letter to Comment on: The Effect of Antihypertensive Therapy on Skeletal Muscle Mass and Bone Mineral Density in Patients With End-Stage Kidney Disease.","authors":"Rena Suzukawa, Shintaro Mandai, Hiroko Hashimoto, Satomi Shikuma, Mai Kimura, Hayato Toma, Yuki Sakaguchi, Sayuka Shiraishi, Noriyuki Toshima, Motoki Hoshino, Moe Kimura, Jun Ota, Susumu Horiuchi, Susumu Adachi, Shinichi Uchida","doi":"10.1053/j.jrn.2025.03.003","DOIUrl":"10.1053/j.jrn.2025.03.003","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional intake and diet quality in hemodialysis patients: Scope for improvement.","authors":"Manon de Geus, Wesley Visser, Anneke van Egmond-de Mik, Manouk Dam, Evelien de Cuyper, Marian de van der Schueren, Michael Tieland, Peter Weijs, Hinke Kruizenga, Karin Ipema","doi":"10.1053/j.jrn.2025.03.004","DOIUrl":"https://doi.org/10.1053/j.jrn.2025.03.004","url":null,"abstract":"<p><strong>Objective: </strong>Hemodialysis (HD) patients face challenges in upholding dietary compliance. This study aimed to compare dietary intake against disease-specific guidelines. Secondary, to assess the overall diet quality and to explore the association between dietary potassium intake and serum potassium concentrations.</p><p><strong>Methods: </strong>In this cross-sectional multicenter study, nutrient intake of Dutch adult HD patients was assessed using food frequency questionnaires (FFQs), and diet quality with the Dutch Healthy Diet 15-index(DHD15-index). Intake and diet quality were compared to disease-specific dietary recommendations or Dutch Dietary Guidelines. Insufficient intake was defined as <90% of the requirement, sufficient as 90-100%, and excessive as >110%. The association between serum potassium concentration and dietary potassium intake was modeled with linear regression analysis.</p><p><strong>Results: </strong>Study population consisted of 248 participants (60% male) from 21 dialysis centers. Energy intake (1789[872] kcal/day) was insufficient for 45% of the participants, while protein intake (1[0.5] g/kg/d) was insufficient for 50%. Despite 67% of participants managing to align their energy intake below 110% of the recommended level, a high prevalence of overweight (61%) was observed in this cohort. Saturated fat intake was excessive for 87% of participants, while only 15% met the recommended fiber intake. Overall diet quality was low (74[20] maximum score of 150). No association was observed between serum potassium and dietary potassium intake after adjusting for relevant confounders (r= 0.163, P= 0.261).</p><p><strong>Conclusions: </strong>A considerable proportion of Dutch HD patients were unable to meet disease-specific dietary guidelines. Diet quality was shown to be poor.</p>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating Nutrition Therapy for Autosomal Dominant Polycystic Kidney Disease (ADPKD).","authors":"Diana Bruen","doi":"10.1053/j.jrn.2025.02.007","DOIUrl":"https://doi.org/10.1053/j.jrn.2025.02.007","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plant-based Diet and Chronic Kidney Disease: A Systematic Review and Meta-analysis.","authors":"Zihan Dang, Yifan He, Ruiqian Xie, Peilin Chen, Fengyu Dong","doi":"10.1053/j.jrn.2025.03.002","DOIUrl":"https://doi.org/10.1053/j.jrn.2025.03.002","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to perform a systematic review and meta-analyses to evaluate the impact of plant-based diet (PBD) on chronic kidney disease (CKD).</p><p><strong>Methods: </strong>A systematic search of PubMed and Embase was conducted from inception to August 2023 to evaluate the association between adopting a PBD and the incidence, progression, and mortality of CKD. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using a random-effects model. This meta-analysis was pre-registered in the PROSPERO.</p><p><strong>Results: </strong>A total of 121,927 participants were included, aged between 18 and 74 years, and were followed up for a weighted average of 11.2 years. Adopting PBD is associated with a significantly reduced risk of developing CKD OR=0.75, 95% CI (0.65, 0.86), P<0.0001] across 93,857 participants. Similar results were observed in subgroup analyses that examined higher quintiles/quartiles (Q2-Q5) and tertiles (T2-T3) of PBD vs Q1/T1, with overall effect measures of 0.92 (95% CI; 0.86 to 0.98) and 0.88 (95% CI; 0.82 to 0.93), respectively. When adjusting for CKD-related comorbidities in patients following PBD (adjusted models M1, M2, and M3), significant findings were also observed, with an overall OR of 0.86 (95% CI: 0.79 to 0.93).</p><p><strong>Conclusion: </strong>Adopting PBD was significantly associated with 26% lower incidences of CKD. Higher intake of PBD showed a dose-dependent relationship with lower risk of CKD incidence and slower CKD progression. Unhealthy PBD may not confer renal protective effects compared to healthy PBD.</p>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Still a Long Way to Go, the Potential of ChatGPT in Personalized Dietary Prescription, From a Perspective of a Clinical Dietitian.","authors":"Qian You, Xuemei Li, Lei Shi, Zhiyong Rao, Wen Hu","doi":"10.1053/j.jrn.2025.02.008","DOIUrl":"10.1053/j.jrn.2025.02.008","url":null,"abstract":"<p><strong>Objective: </strong>Prominent large language models, such as OpenAI's Chat Generative Pre-trained Transformer (ChatGPT), have shown promising implementation in the field of nutrition. Special care should be taken when using ChatGPT to prescribe protein-restricted diets for kidney-impaired patients. The objective of the current study is to simulate a chronic kidney disease (CKD) patient and evaluate the capabilities of ChatGPT in the context of dietary prescription, with a focus on protein contents of the diet.</p><p><strong>Methods: </strong>We simulated a scenario involving a CKD patient and replicated a clinical counseling session that covered general dietary principles, dietary assessment, energy and protein recommendation, dietary prescription, and diet customization based on dietary culture. To confirm the results derived from our qualitative observations, 10 colleagues were recruited and provided with identical dietary prescription prompts to run the process again. The actual energy and protein levels of the given meal plans were recorded and the difference from the targets were compared.</p><p><strong>Results: </strong>ChatGPT provides general principles overall aligning with best practices. The recommendations for energy and protein requirements of CKD patients were tailored and satisfactory. It failed to prescribe a reliable diet based on the target energy and protein requirements. For the quantitative analysis, the prescribed energy levels were generally lower than the targets, ranging from -28.9% to -17.0%, and protein contents were tremendously higher than the targets, ranging from 59.3% to 157%.</p><p><strong>Conclusion: </strong>ChatGPT is competent in offering generic dietary advice, giving satisfactory nutrients recommendations and adapting cuisines to different cultures but failed to prescribe nutritionally accurate dietary plans for CKD patients. At present, patients with strict protein and other particular nutrient restrictions are not recommended to rely on the dietary plans prescribed by ChatGPT to avoid potential health risks.</p>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low Skeletal Muscle Density Assessed by Abdominal Computerized Tomography Predicts Outcome in Children With Chronic Kidney Disease","authors":"Meiqiu Wang MD ,&nbsp;Zijian Chen BS ,&nbsp;Tingting Yu MS ,&nbsp;Lianghui You MD ,&nbsp;Yingchao Peng MD ,&nbsp;Huangyu Chen MS ,&nbsp;Pei Zhang MD ,&nbsp;Zhuo Shi MS ,&nbsp;Xiang Fang MD ,&nbsp;LiLi Jia BS ,&nbsp;Zhengkun Xia MD ,&nbsp;Chenbo Ji PhD, MD ,&nbsp;Hao Tang MS ,&nbsp;Chunlin Gao MD","doi":"10.1053/j.jrn.2024.11.003","DOIUrl":"10.1053/j.jrn.2024.11.003","url":null,"abstract":"<div><h3>Objectives</h3><div>Skeletal muscle loss and abnormal fat distribution are predictors of poor clinical outcomes in adults with chronic kidney disease (CKD). However, the relationship between body composition (muscle mass and adipose tissue) and prognosis in children with CKD has not been well elucidated.</div></div><div><h3>Methods</h3><div>The retrospective single-center study enrolled children with CKD and healthy group who underwent an abdominal computerized tomography examination and compared the body composition of the third lumbar spine (L3) between the 2 groups. We defined the primary outcome as hemodialysis, peritoneal dialysis, kidney transplantation, or death. Logistic regression analysis was applied to assess the connection between low skeletal muscle density (SMD) and clinical and demographic variables. Multivariate Cox regression analysis was used to evaluate the risk factors for progression to the primary outcome. Kaplan-Meier survival analysis was performed to compare the effect of different body composition on event-free survival rate.</div></div><div><h3>Results</h3><div>Thirty-two patients with CKD [estimated glomerular filtration rate: 14.89 (8.86, 29.88) (mL/min/1.73 m²)] and 66 heathy subjects [estimated glomerular filtration rate: 135.72 (121.70, 161.29) (mL/min/1.73 m²)] were recruited in our study. From the assessment of body composition assessed by computerized tomography, skeletal muscle area, SMD, and skeletal muscle index in the CKD group was lower than those in the healthy group (<em>P</em> &lt; .05). On the other hand, visceral fat area and visceral fat index in the CKD group were significantly higher than those in the healthy group (<em>P</em> &lt; .05). In logistic regression analysis, triglyceride (odds ratio: 8.635, 95% confidence interval (CI): 1.153-64.687) was independently associated with low SMD. After adjusting clinical data and body composition, high serum albumin (hazard ratio: 0.873, 95% CI: 0.798-0.955) and high SMD (hazard ratio: 0.895, 95% CI: 0.822-0.974) were protective factors for delaying renal failure. Based on the Kaplan-Meier analysis, only the group with low SMD had lower event-free survival in comparison to the reference group (<em>P</em> &lt; .05).</div></div><div><h3>Conclusions</h3><div>These findings suggest that there is significant skeletal muscle loss and decrease in SMD in CKD children. Notably, low SMD is indicative of poor prognosis in CKD children.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"35 2","pages":"Pages 281-288"},"PeriodicalIF":3.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142645110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}