Journal of Renal Nutrition最新文献

{"title":"Letter to the Editor “Development and Validation of a Knowledge, Attitude, and Practice (KAP) 2 Questionnaire and Its Utility Study Toward Nutritional Habits Among Non-dialytic Chronic Kidney Disease 3 Patients”","authors":"Rachana Mehta MSc, Ranjana Sah MD","doi":"10.1053/j.jrn.2025.07.014","DOIUrl":"10.1053/j.jrn.2025.07.014","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 4","pages":"Pages 641-642"},"PeriodicalIF":4.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146021133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Evaluation of Online Guidance for Managing Hyperkalemia Through Dietary Approaches in Individuals With Chronic Kidney Disease","authors":"Masuda Akter MS,&nbsp;Annabel Biruete PhD, RD,&nbsp;Brandon Kistler PhD, RD,&nbsp;Anthony Meade BSc, MND, APD,&nbsp;David E. St-Jules PhD, RD","doi":"10.1053/j.jrn.2026.03.001","DOIUrl":"10.1053/j.jrn.2026.03.001","url":null,"abstract":"<div><h3>Objective</h3><div>The scientific literature on diet therapy for managing hyperkalemia risk in people with kidney disease has shifted in the last decade away from a focus on restricting potassium-rich foods. However, the extent to which this change is reflected in online resources has not been systematically studied.</div></div><div><h3>Design and Methods</h3><div>The first 50 webpages from Google and Bing search engines were obtained using the terms “diet\" and “potassium\" with: 1) hyperkalemia, 2) high blood potassium, 3) kidney disease, 4) dialysis, 5) kidney failure, 6) chronic kidney disease, 7) low, and 8) restriction. Dietary guidance was classified as recommended, restricted, or mixed using a hierarchical approach (e.g., advice to restrict oranges was also counted as restricting citrus fruit and fruit). After removing duplicate (n = 468) and unrelated/excluded resources (n = 224), 106 resources (13.3%) were available for analyses.</div></div><div><h3>Results</h3><div>Online resources provided advice on 559 food items. Fruit and vegetables comprised the majority of restrictions (59%) and recommendations (58%). Plant-based protein foods, low-fat dairy products, and whole grains tended to restricted, and animal-based protein foods, high-fat dairy products, and refined grains tended to be recommended. Dietary guidance was usually at the level of individual food items, often restricting (nectarines) and recommending (peaches) foods in the same sub-group, and more than half of the food items (55%) mentioned in at least two resources had inconsistent advice across resources (restricted and recommended).</div></div><div><h3>Conclusion</h3><div>Dietary guidance online for managing hyperkalemia risk did not reflect recent shifts in the literature and primarily consisted of complicated food lists that lacked consistency. Research is needed to standardize and evaluate the efficacy of the food list–based approach to practice.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 4","pages":"Pages 594-601"},"PeriodicalIF":4.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147492109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: Computed Tomography–Based Abdominal Myosteatosis Indicators and Handgrip Strength in Hemodialyzed Patients","authors":"Tirayut Veerasatian MD,&nbsp;Schawanya K. Rattanapitoon MD,&nbsp;Patpicha Arunsan PhD,&nbsp;Nathkapach K. Rattanapitoon PhD","doi":"10.1053/j.jrn.2026.01.009","DOIUrl":"10.1053/j.jrn.2026.01.009","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 4","pages":"Pages 645-646"},"PeriodicalIF":4.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical Activity and Exercise in Patients With Coexisting Chronic Kidney Disease and Peripheral Artery Disease: Time to Bridge the Gap?","authors":"Federica Caccia MSc,&nbsp;Federica Baciga MD,&nbsp;Claudia Baschirotto MSc,&nbsp;Nicola Lamberti MD,&nbsp;Tania Cappellari MD,&nbsp;Alda Storari MD,&nbsp;Bruno Migliara MD,&nbsp;Michele Andreucci MD,&nbsp;Chayakrit Krittanawong MD,&nbsp;Massimo Venturelli PhD,&nbsp;Roberto Manfredini MD,&nbsp;Kenneth R. Wilund PhD,&nbsp;Fabio Manfredini MD,&nbsp;Yuri Battaglia MD, PhD","doi":"10.1053/j.jrn.2026.02.008","DOIUrl":"10.1053/j.jrn.2026.02.008","url":null,"abstract":"<div><div>Chronic kidney disease (CKD) and peripheral artery disease (PAD) are highly prevalent conditions associated with morbidity, mortality, and health-care costs, particularly when they coexist. Despite advances in pharmacological and interventional therapies, patients with both CKD and PAD have rapid functional decline, higher hospitalization rates, and poor cardiovascular outcomes. In populations with either CKD or PAD alone, exercise training has been shown to improve cardiorespiratory fitness, muscle strength, physical function, and quality of life and is strongly recommended in the guidelines. However, evidence for exercise training in patients with overlapping CKD and PAD remains limited with no randomized controlled trials and only a single observational cohort, suggesting potential benefits of home-based walking programs on renal and cardiovascular outcomes. This narrative review examines the potential benefits of exercise training as a nonpharmacological approach to addressing this therapeutic gap. An ongoing randomized controlled trial, EXACT-CKD–PAD, is expected to provide more definitive evidence in this high-risk population, although further studies will be required to define long-term clinical impact and optimal implementation strategies.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 4","pages":"Pages 560-570"},"PeriodicalIF":4.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147518345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vegetarian Dietary Patterns and Diet-Related Metabolites Are Associated With Kidney Function in the Adventist Health Study-2 Cohort","authors":"Fayth M. Butler PhD ,&nbsp;Roy O. Mathew MD ,&nbsp;Lars E. Sveen ,&nbsp;Gary E. Fraser MbCHB, PhD","doi":"10.1053/j.jrn.2025.11.001","DOIUrl":"10.1053/j.jrn.2025.11.001","url":null,"abstract":"<div><h3>Objectives</h3><div>Chronic kidney disease is a significant global health burden. Plant-based diets have shown potential benefits for kidney function, but the specific impacts of vegetarian dietary patterns and underlying metabolic mechanisms remain unclear.</div></div><div><h3>Methods</h3><div>Serum creatinine was measured in 899 Adventist Health Study-2 cohort participants who were classified as vegan, lacto-ovo-vegetarian, pesco-vegetarian, semivegetarian, or nonvegetarian, and estimated glomerular filtration rate (eGFR) was calculated (&lt;60 or &gt;/ = 60 mL/min/1.73 m²). Untargeted plasma metabolomics using ultra-performance liquid chromatography–mass spectrometry/mass spectrometry was performed on a subset of participants with serum creatinine measurements. Multivariable linear regression models adjusted for confounders assessed associations between eGFR, dietary patterns, and plasma metabolites. The Storey permutation approach was used to adjust for false discovery.</div></div><div><h3>Results</h3><div>Vegan and pesco-vegetarian dietary patterns were associated with significantly higher eGFR compared to nonvegetarians, with minimal attenuation after adjustment. Metabolomics analysis revealed distinct profiles in relation to creatinine, comparing the 90th to 10th percentiles. Creatinine was positively associated with several lipid and amino acid subclasses, which were lower in participants following vegetarian dietary patterns. Key subclasses included acetylated peptides, histidine metabolism, lysine metabolism, plasmalogens, and notably sphingomyelins for pesco-vegetarians. Individual metabolites within many of the differential subclasses consistently showed opposite directions of associations with vegetarian dietary patterns and creatinine.</div></div><div><h3>Conclusions</h3><div>Vegan and pesco-vegetarian dietary patterns, relative to nonvegetarian, were associated with higher eGFR, potentially through diet-driven metabolic pathways. Plant-based diets may offer protection against chronic kidney disease by modulating key metabolic pathways.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 3","pages":"Pages 398-409"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145644515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Letter to the Editor: Lack of Association Between Dietary Fiber Intake and Kidney Failure Among Patients With Chronic Kidney Disease: The Chronic Kidney Disease-Japan Cohort Study","authors":"Yusuke Sakaguchi MD, PhD,&nbsp;Koki Hattori MD, PhD,&nbsp;Yoshitaka Isaka MD, PhD","doi":"10.1053/j.jrn.2025.10.020","DOIUrl":"10.1053/j.jrn.2025.10.020","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 3","pages":"Page 530"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145728200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Food Skills in Caregivers of Children With Chronic Kidney Disease","authors":"Meredith Cushing RD, MSc, MSHSE ,&nbsp;Janis Dionne MD, FRCPC ,&nbsp;Mina Matsuda-Abedini MDCM, FRCPC ,&nbsp;Kiana Gibson BSc ,&nbsp;Alicia Walch BSc ,&nbsp;Ye Shen MSPH","doi":"10.1053/j.jrn.2025.12.004","DOIUrl":"10.1053/j.jrn.2025.12.004","url":null,"abstract":"<div><h3>Objectives</h3><div>Assessed change in food skills, food selection and planning, food preparation, and overall food skills, in caregivers of children with chronic kidney disease (CKD) following a series of virtual cooking classes.</div></div><div><h3>Design and Methods</h3><div>Prepost design using the Food Skills Questionnaire.</div></div><div><h3>Setting</h3><div>Chronic Kidney Care Clinic, CKD stage 3-5 (not on dialysis).</div></div><div><h3>Subjects</h3><div>Caregivers of patients aged 1-20 with CKD stage 3-5 (not on dialysis) who attended the Chronic Kidney Care Clinic. Proficient in English, expressed interest in attending all 3 sessions, and had access to a reliable device such as a tablet, cell phone, or computer with a reliable internet connection.</div></div><div><h3>Intervention</h3><div>Three virtual cook-along classes demonstrating kidney-friendly, kid-friendly, and budget-friendly recipes, held 2-3 weeks apart. Sessions included education around appropriate food selection and modifications for the CKD diet, basic cooking skills, and food safety.</div></div><div><h3>Main outcome measure</h3><div>Analysis of the Food Skills Questionnaire provided a score in each of the three domains; food selection and planning, food preparation, and food safety and storage as well as a total score. Preintervention and postintervention scores were compared using a paired t-test.</div></div><div><h3>Results</h3><div>A statistically significant increase was observed in the score for the food safety and storage domain (mean difference [MD] in score +4.24, <em>P</em> value 0.02). An increase was observed in scores for domains, food selection and planning (MD +6.34, <em>P</em> value 0.07), 2), food preparation (MD +1.92, <em>P</em> value 0.35), and total score (MD +3.54, <em>P</em> value 0.08), but did not reach statistical significance.</div></div><div><h3>Conclusions</h3><div>Food safety and food storage skills significantly improved in caregivers of a child with CKD after attending virtual cooking classes. Virtual cooking classes have a potential to be an accessible, practical, and affordable approach to the nutritional management of pediatric CKD.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 3","pages":"Pages 381-386"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146021108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protein-Energy Wasting Among Patients With Nondialysis Chronic Kidney Disease: Comparing ISRNM and GLIM Criteria With Malnutrition Inflammation Score","authors":"Ting-Yun Lin MD,&nbsp;Szu-Chun Hung MD","doi":"10.1053/j.jrn.2025.12.006","DOIUrl":"10.1053/j.jrn.2025.12.006","url":null,"abstract":"<div><h3>Objective</h3><div>Protein-energy wasting (PEW) is a critical complication among patients with chronic kidney disease (CKD). The International Society of Renal Nutrition and Metabolism (ISRNM) and Global Leadership Initiative on Malnutrition (GLIM) criteria have been proposed for PEW diagnosis, yet their accuracy and prognostic relevance in nondialysis CKD populations remain underexplored.</div></div><div><h3>Methods</h3><div>In a prospective cohort of 156 nondialysis patients with CKD stages 3-5, PEW was assessed using the ISRNM, GLIM criteria, and the PEW score, with Malnutrition-Inflammation Score (MIS) (cutoff ≥ 5) serving as the reference standard. Diagnostic performance was determined by sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). Prognostic significance was examined using Cox models for a composite outcome of end-stage kidney disease or all-cause mortality.</div></div><div><h3>Results</h3><div>Participants had a median age of 66.0 years, 41% were women, and 38% had diabetes. PEW was identified in 33 patients (21.2%) by MIS, 24 (15.4%) by ISRNM, and 22 (14.1%) by GLIM. Compared to the MIS, the ISRNM criteria exhibited low sensitivity (30.3%) but high specificity (88.6%), with a PPV of 41.7% and NPV of 82.6%. The GLIM criteria yielded similar metrics. In contrast, the PEW score showed higher sensitivity (75.8%) but lower specificity (50.4%), with a PPV of 29.1% and an NPV of 88.6%. Furthermore, MIS-defined PEW was associated with increased risk of end-stage kidney disease or death (adjusted hazard ratio 1.92; 95% confidence interval, 1.04-3.52; <em>P</em> = .036), whereas PEW defined by ISRNM, GLIM, or the PEW score was not.</div></div><div><h3>Conclusions</h3><div>The ISRNM and GLIM criteria show limited utility as screening tools for PEW due to poor sensitivity in nondialysis CKD populations. Although the PEW score demonstrates higher sensitivity, its diagnostic specificity is suboptimal. The MIS offers superior prognostic discrimination and may serve as a more appropriate reference for future PEW diagnostic frameworks.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 3","pages":"Pages 473-481"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146000421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic Kidney Disease, Nutrition, and the Brain: How to Maintain Brain Health Through Nutrition in Chronic Kidney Disease","authors":"Hélène Levassort MD, PhD ,&nbsp;Théodore Decaix MD, PhD ,&nbsp;Pierre-Louis Michon MD ,&nbsp;Marion Pépin MD, PhD ,&nbsp;Matthieu Lilamand MD, PhD","doi":"10.1053/j.jrn.2026.01.005","DOIUrl":"10.1053/j.jrn.2026.01.005","url":null,"abstract":"<div><div>Chronic kidney disease (CKD) is increasingly recognized not only as a kidney disorder but also as a contributor to cognitive impairment (CI). The kidney and brain share a common vulnerability to uremic toxins, whose accumulation in CKD is exacerbated by gut dysbiosis. These toxins impair the integrity of the blood-brain barrier (BBB), reduce neurogenesis, and promote neuroinflammation. Therefore, maintaining brain health in CKD requires a holistic approach targeting the gut–kidney–brain axis. Nutritional strategies, particularly plant-based diets such as the Mediterranean or dietary approaches to stop hypertension (DASH) diets, have demonstrated benefits for both renal and cerebral outcomes. Because dietary interventions alone may be insufficient, combining nutritional approaches with physical activity and pharmacological strategies, such as Glucagon-Like Peptide-1 (GLP-1) receptor agonists or Sodium Glucose Co-Transporter 2 (SGLT2) inhibitors, may offer synergistic effects. Understanding and modulating the interactions between diet, microbiota, and uremic toxins is essential to preserve cognitive and kidney function in CKD patients, highlighting the need for integrated care.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 3","pages":"Pages 353-364"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146129212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"May Meeting Announcements","authors":"","doi":"10.1053/j.jrn.2026.03.007","DOIUrl":"10.1053/j.jrn.2026.03.007","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 3","pages":"Page 536"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148103682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}