Manon de Geus MSc , Wesley Visser PhD , Anneke van Egmond-de Mik BSc , Manouk Dam PhD , Evelien de Cuyper BSc , Marian de van der Schueren (Prof.) , Michael Tieland PhD , Peter Weijs (Prof.) , Hinke Kruizenga PhD , Karin Ipema PhD
{"title":"Nutritional Intake and Diet Quality in Hemodialysis Patients: Scope for Improvement","authors":"Manon de Geus MSc , Wesley Visser PhD , Anneke van Egmond-de Mik BSc , Manouk Dam PhD , Evelien de Cuyper BSc , Marian de van der Schueren (Prof.) , Michael Tieland PhD , Peter Weijs (Prof.) , Hinke Kruizenga PhD , Karin Ipema PhD","doi":"10.1053/j.jrn.2025.03.004","DOIUrl":"10.1053/j.jrn.2025.03.004","url":null,"abstract":"<div><h3>Objective</h3><div>Hemodialysis (HD) patients face challenges in upholding dietary compliance. This study aimed to compare dietary intake against disease-specific guidelines. Secondary, to assess the overall diet quality and to explore the association between dietary potassium intake and serum potassium concentrations.</div></div><div><h3>Methods</h3><div>In this cross-sectional multicenter study, nutrient intake of Dutch adult HD patients was assessed using food frequency questionnaires and diet quality with the Dutch Healthy Diet 15-index. Intake and diet quality were compared to disease-specific dietary recommendations or Dutch Dietary Guidelines. Insufficient intake was defined as <90% of the requirement, sufficient as 90-100%, and excessive as >110%. The association between serum potassium concentration and dietary potassium intake was modeled with linear regression analysis.</div></div><div><h3>Results</h3><div>The study population consisted of 248 participants (60% male) from 21 dialysis centers. Energy intake (1789 [872] kcal/day) was insufficient for 45% of the participants, while protein intake (1 [0.5] g/kg/d) was insufficient for 50%. Despite 67% of participants managing to align their energy intake below 110% of the recommended level, a high prevalence of overweight (61%) was observed in this cohort. Saturated fat intake was excessive for 87% of participants, while only 15% met the recommended fiber intake. Overall diet quality was low (74 [20] maximum score of 150). No association was observed between serum potassium and dietary potassium intake after adjusting for relevant confounders (<em>r</em> = 0.163, <em>P</em> = .261).</div></div><div><h3>Conclusions</h3><div>A considerable proportion of Dutch HD patients were unable to meet disease-specific dietary guidelines. Diet quality was shown to be poor.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"35 4","pages":"Pages 550-558"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Amino Acid Kinetics During Low-Dose Continuous Renal Replacement Therapy in Patients With Acute Kidney Injury: A Prospective Single-Center Study","authors":"Hiroomi Tatsumi MD, PhD , Shinya Chihara MD, PhD , Masayuki Akatsuka MD, PhD , Hiromitsu Kuroda MD, PhD , Satoshi Kazuma MD, PhD , Miyuki Tani MS , Satoru Kamoshita BA , Akiyoshi Kuroda PhD , Yoshiki Masuda MD, PhD","doi":"10.1053/j.jrn.2025.02.004","DOIUrl":"10.1053/j.jrn.2025.02.004","url":null,"abstract":"<div><h3>Objective</h3><div>Amino acid and protein loss during continuous renal replacement therapy has been proposed to contribute to protein-energy wasting in patients with acute kidney injury (AKI); however, the actual amount removed remains unclear. We investigated the loss of amino acids and proteins in the filtrate during continuous renal replacement therapy in patients who did not receive nutritional supplementation.</div></div><div><h3>Methods</h3><div>A total of 19 patients with AKI who received low-dose continuous venovenous hemofiltration (CVVH) were included. Blood samples were collected before CVVH initiation and at 30, 60, 120, and 240 minutes thereafter, and a filtrate sample was collected at 240 minutes. Changes in blood amino acid concentrations during 240-minute CVVH sessions were measured. The amino acid and protein concentrations in the filtrate were determined at the end of the 240-minute CVVH session, and the amounts of amino acids and proteins lost during 240-minute CVVH were calculated.</div></div><div><h3>Results</h3><div>The median total amino acid blood concentrations did not decrease and were near the lower limits of the reference ranges. The median concentrations of 3-methyl histidine, a marker of skeletal muscle catabolism, were above the upper limits of the reference ranges throughout the CVVH session. The median total amino acidloss during the 240-minute CVVH session was 0.95 g. In 10 patients with detectable proteins in the filtrate, the median protein loss was 2.52 g.</div></div><div><h3>Conclusion</h3><div>These results suggest that optimal nutritional management in patients with AKI who receive CVVH should take into account amino acid and protein loss and hypercatabolism.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"35 4","pages":"Pages 494-500"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: The Effect of Antihypertensive Therapy on Skeletal Muscle Mass and Bone Mineral Density in Patients With End-Stage Kidney Disease","authors":"Aqsa Sabir MBBS, Alaita Fatima Bakhtiari MBBS","doi":"10.1053/j.jrn.2025.01.009","DOIUrl":"10.1053/j.jrn.2025.01.009","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"35 4","pages":"Pages 559-560"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Message From the ChairPerson","authors":"Jill Hoyt RDN, CD, FNKF","doi":"10.1053/j.jrn.2025.04.003","DOIUrl":"10.1053/j.jrn.2025.04.003","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"35 4","pages":"Page 563"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response Letter to Comment on: The Effect of Antihypertensive Therapy on Skeletal Muscle Mass and Bone Mineral Density in Patients With End-Stage Kidney Disease","authors":"Rena Suzukawa, Shintaro Mandai MD, PhD, Hiroko Hashimoto MD, PhD, Satomi Shikuma MD, Mai Kimura MD, Hayato Toma MD, Yuki Sakaguchi MD, Sayuka Shiraishi MD, Noriyuki Toshima MD, Motoki Hoshino MD, Moe Kimura MD, Jun Ota MD, Susumu Horiuchi MD, Susumu Adachi MD, Shinichi Uchida MD","doi":"10.1053/j.jrn.2025.03.003","DOIUrl":"10.1053/j.jrn.2025.03.003","url":null,"abstract":"","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"35 4","pages":"Pages 560-561"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christiane Ishikawa Ramos PhD , Laila Santos de Andrade PhD , Renata Rodrigues Teixeira MD , Natália Barros Ferreira Pereira MD , Fabiana da Silva Lima PhD , Christian Hoffmann PhD , Lilian Cuppari PhD
{"title":"Diet Quality Components and Gut Microbiota of Patients on Peritoneal Dialysis","authors":"Christiane Ishikawa Ramos PhD , Laila Santos de Andrade PhD , Renata Rodrigues Teixeira MD , Natália Barros Ferreira Pereira MD , Fabiana da Silva Lima PhD , Christian Hoffmann PhD , Lilian Cuppari PhD","doi":"10.1053/j.jrn.2025.01.001","DOIUrl":"10.1053/j.jrn.2025.01.001","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the associations between the quality of the diet and its components and microbial diversity and composition in peritoneal dialysis (PD) patients.</div></div><div><h3>Design and Methods</h3><div>This cross-sectional study included PD patients for at least 3 months, aged 18-75 years and clinically stable. The Diet Quality Index (DQI), validated for the Brazilian population, is based on the energy density of 11 components (“sugar and sweets;” “beef, pork, and processed meat;” “refined grains and breads;” “animal fat;” “poultry, fish, and eggs;” “whole cereals, tubers, and roots;” “fruits”; “nonstarch vegetables;” “legumes and nuts;” “milk and dairy products;” and “vegetable oil”). A proportional score—based on the adequacy of the intake to Brazilian dietary guidelines—is calculated, and a final score ranged from 0 (worse) to 100 (better) is obtained. Fecal samples were collected at home, in a sterile material, kept refrigerated, and delivered to the clinic within 12 hours; α-diversity indices (Observed operational taxonomic units, Chao-1, Shannon’s, Gini-Simpson’s, Pielou eveness, and Faith phylogenetics) and microbial profile were determined by 16S ribosomal DNA with polymerase chain reaction-amplification and sequenced on an Illumina MiSeq platform.</div></div><div><h3>Results</h3><div>Forty-three participants were included (53.5% men, 52.4 ± 14.1 years, body mass index: 25.9 ± 4.1 kg/m<sup>2</sup>, 30.2% had diabetes mellitus). DQI score was 50.5 (41.9-54.9). The lowest energy density was for the components “animal fat” and “whole cereals and breads, tubers, and roots,” and the highest were for “refined grains and bread” and “beef, pork, and processed meat.” Diversity indices and <em>Enterorhabdus</em> genus were directly associated with the energy density of the components “whole cereals and breads, tubers, and roots” and inversely with “refined grains and bread,” after adjustments for age and diabetes.</div></div><div><h3>Conclusions</h3><div>Even low, the intake of whole cereals, tubers, and roots has the potential to positively influence the microbiota profile in PD patients.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"35 3","pages":"Pages 454-462"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kristina L. Penniston PhD, RDN , Mariana M. Coughlin MS , R. Allan Jhagroo MD
{"title":"Magnesium Supplementation Increases Urine Magnesium and Citrate in Stone Formers With Hypomagnesuria","authors":"Kristina L. Penniston PhD, RDN , Mariana M. Coughlin MS , R. Allan Jhagroo MD","doi":"10.1053/j.jrn.2024.06.002","DOIUrl":"10.1053/j.jrn.2024.06.002","url":null,"abstract":"<div><h3>Objectives</h3><div>To compare the effects of magnesium repletion by a foods-alone approach or by magnesium supplementation on urinary magnesium and citrate excretion in patients with urine magnesium <70 mg/day.</div></div><div><h3>Methods</h3><div>We reviewed medical records of patients in our stone prevention practice who were advised to start a magnesium supplement (Sup), 250-500 mg/day, or increase dietary magnesium consumption. We included adults with 24-hour urine magnesium (UMg) <70 mg, those who received magnesium recommendations (corroborated by the dietitian’s clinical notes), and those with a follow-up 24-hour urine collection ≤18 months. Urine results were assessed by group.</div></div><div><h3>Results</h3><div>Groups [No Sup (n = 74) and Sup (n = 56)] were not different for age, gender, stone history, malabsorption, or other clinical indices. All patients raised UMg (53-69 and 47-87 mg/day for No Sup and Sup, respectively); however, the increase was significantly higher in the Sup group. Moreover, while 88% of Sup patients achieved UMg ≥70 mg/day, only 58% in the No Sup group did so. Within-group increases in urine citrate were significant only in the Sup group.</div></div><div><h3>Conclusion</h3><div>Among patients with low UMg, both higher consumption from foods and magnesium supplementation significantly increased UMg. However, those who supplemented were significantly more likely to reach or exceed UMg 70 mg/day and achieved higher mean UMg. The change in urine citrate was significant only among those in the Sup group.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"35 3","pages":"Pages 393-400"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141428130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}