Journal of Rheumatology最新文献_第5页

Tight Control and Radiological Progression: The Radiographic Outcomes of the TICOPA Study. 严格控制疾病是否会阻碍放射学进展？TICOPA研究的影像学结果。

IF 3.6 2区医学

Journal of Rheumatology Pub Date : 2025-05-01 DOI: 10.3899/jrheum.2024-1035

Lija James, Philip S Helliwell, Elizabeth M A Hensor, Philip G Conaghan, Paul Emery, Laura C Coates

{"title":"Tight Control and Radiological Progression: The Radiographic Outcomes of the TICOPA Study.","authors":"Lija James, Philip S Helliwell, Elizabeth M A Hensor, Philip G Conaghan, Paul Emery, Laura C Coates","doi":"10.3899/jrheum.2024-1035","DOIUrl":"10.3899/jrheum.2024-1035","url":null,"abstract":"Objective: The Tight Control of Psoriatic Arthritis (TICOPA) study was the first to undertake the treat-to-target approach in psoriatic arthritis (PsA). Our aim was to further investigate the radiographic changes in the TICOPA study.Methods: The TICOPA trial recruited patients with early treatment-naïve PsA. Plain radiographs of the hands and feet were taken at weeks 0 and 48. Clinical outcomes were recorded by a blinded assessor every 12 weeks. In post hoc analysis, bootstrapped quantile regression, adjusting for baseline values and minimization factors, was used to compare radiographic scores (modified Sharp/van der Heijde [mSvdH]), defined according to treatment arm or disease activity states.Results: Paired baseline and week 48 radiographs were available for 169/206 (82%) at week 48 (84 tight control [TC] arm, 85 standard care [StdC] arm). There was no difference in change in total mSvdH score seen with TC compared to StdC (median [IQR] 0.0 [-2.0 to 0.5] vs 0.0 [-2.0 to 0.0]; difference 0.0 [95% CI 0.0-0.0]). Median total mSvdH score change was lower in those achieving minimal disease activity, Disease Activity in Psoriatic Arthritis remission, and very low disease activity. The number of people with radiographic progression (an increase in total erosion score of ≥ 2 at week 48) was numerically lower in the TC group (5/84 [5.9%] vs 12/85 [14.1%]). Patients with radiographical progression presented with polyarticular disease and high C-reactive protein, and had poorer clinical outcomes at weeks 12 and 24.Conclusion: These data confirm the benefit of achieving low disease activity states on subsequent radiographic outcomes but did not show a significant impact related to a TC management approach.","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"460-465"},"PeriodicalIF":3.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tight Control and Radiological Progression: The Radiographic Outcomes of the TICOPA Study. 严格控制和放射学进展：TICOPA研究的放射学结果。

IF 3.6 2区医学

Journal of Rheumatology Pub Date : 2025-05-01 DOI: 10.3899/jrheum.2024-1035.C1

Lija James, Philip S Helliwell, Elizabeth M A Hensor, Philip G Conaghan, Paul Emery, Laura C Coates

引用次数: 0

Practical Issues Relating to the Use of Antifibrotic Therapy in Patients With Interstitial Lung Disease and Rheumatoid Arthritis. 与间质性肺疾病和类风湿关节炎患者使用抗纤维化治疗有关的实际问题。

IF 3.6 2区医学

Journal of Rheumatology Pub Date : 2025-05-01 DOI: 10.3899/jrheum.2025-0103

Clive A Kelly, Muddassir Shaikh

引用次数: 0

Pediatric Rheumatology Care in the Canadian Context: A Qualitative Analysis of Care Providers. 加拿大儿童风湿病护理：对护理提供者的定性分析。

IF 3.6 2区医学

Journal of Rheumatology Pub Date : 2025-05-01 DOI: 10.3899/jrheum.2024-0965

Molly J Dushnicky, Eden S Har-Gil, Jennifer J Y Lee, Deborah M Levy

{"title":"Pediatric Rheumatology Care in the Canadian Context: A Qualitative Analysis of Care Providers.","authors":"Molly J Dushnicky, Eden S Har-Gil, Jennifer J Y Lee, Deborah M Levy","doi":"10.3899/jrheum.2024-0965","DOIUrl":"10.3899/jrheum.2024-0965","url":null,"abstract":"Objective: Previous work highlighted a national deficit in pediatric rheumatologists and allied health professionals (AHPs), with a geographic maldistribution in Canada. The aim of this current study was to further evaluate the clinical care structures and processes in place within Canadian pediatric rheumatology centers that promote or impede care delivery from the perspective of pediatric rheumatology healthcare providers.Methods: Data were collected through semistructured interviews with pediatric rheumatologists and Advanced Clinician Practitioners in Arthritis Care (ACPACs) across Canada. Analysis was performed by 2 investigators following the 4 stages of qualitative content analysis: decontextualization, recontextualization, categorization, and compilation. Data were analyzed through latent analysis due to the informal nature of interviews, and themes were identified iteratively.Results: Twelve individuals (9 pediatric rheumatologists, 3 AHPs) agreed to participate in the study. Interviewees practiced across Canada with a range of career experience. The following themes emerged: (1) geographic barriers negatively affect access to care; (2) ACPAC practitioners and community pediatric rheumatologists improve access to care; and (3) there is inconsistent access to physiotherapists, social workers, and occupational therapists who are knowledgeable about pediatric rheumatology care and disease.Conclusion: Although there was variation in pediatric rheumatology practice across Canada, there were common themes of supports and barriers to clinical care. The description of these themes can (1) help guide pediatric rheumatology practice by highlighting thriving practice patterns, and (2) concomitantly emphasize the deficits in resources and functioning, both of which can advise future advocacy work.","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"498-504"},"PeriodicalIF":3.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrocephalus-Related Dementia in Paget Disease of the Skull. 颅骨帕格特病中与脑积水相关的痴呆症

IF 3.6 2区医学

Journal of Rheumatology Pub Date : 2025-05-01 DOI: 10.3899/jrheum.2024-0818

João Daniel Ferreira Carvalho, José Carlos Romeu

引用次数: 0

Assessing Disease Activity in Axial Spondyloarthritis: Finding the Balance Between the Bath Ankylosing Spondylitis Disease Activity Index and Axial Spondyloarthritis Disease Activity Score. 评估中轴性脊柱炎疾病活动性：寻找浴缸强直性脊柱炎疾病活动性指数与中轴性脊柱炎疾病活动性评分之间的平衡。

IF 3.6 2区医学

Journal of Rheumatology Pub Date : 2025-05-01 DOI: 10.3899/jrheum.2025-0258

Antoni T Y Chan

引用次数: 0

Application of EULAR/ACR Classification Criteria for Polymyalgia Rheumatica in a Series of Patients With Acute Parvovirus B19 Infection. EULAR/ACR分级标准在一系列急性细小病毒B19感染患者风湿多肌痛中的应用

IF 3.6 2区医学

Journal of Rheumatology Pub Date : 2025-05-01 DOI: 10.3899/jrheum.2024-1024

Bernardo D'Onofrio, Carlo Selmi

引用次数: 0

Association Between Depressive Symptoms and Self-Reported Physical Activity in Persons With Knee Osteoarthritis. 膝骨关节炎患者抑郁症状与自我报告的体力活动之间的关系

IF 3.6 2区医学

Journal of Rheumatology Pub Date : 2025-05-01 DOI: 10.3899/jrheum.2024-0940

Alan M Rathbun, Alice S Ryan, Michelle D Shardell, Yu Dong, Brock A Beamer, Mark Luborsky, Marc C Hochberg

{"title":"Association Between Depressive Symptoms and Self-Reported Physical Activity in Persons With Knee Osteoarthritis.","authors":"Alan M Rathbun, Alice S Ryan, Michelle D Shardell, Yu Dong, Brock A Beamer, Mark Luborsky, Marc C Hochberg","doi":"10.3899/jrheum.2024-0940","DOIUrl":"10.3899/jrheum.2024-0940","url":null,"abstract":"Objective: Depressive symptoms are common in patients with knee osteoarthritis (KOA) and reduce energy, motivation, and movement; thus, declines in physical activity (PA) could worsen as clinical disease progresses. The objective was to evaluate the longitudinal relationship between depressive symptoms and self-reported PA over time among persons with KOA.Methods: The sample included Osteoarthritis Initiative participants (N = 2602) with radiographic disease (Kellgren-Lawrence grade ≥ 2). Depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale (CES-D; score ≥ 16) at baseline and first 3 follow-up visits. Self-reported PA was assessed with the Physical Activity Scale for the Elderly (PASE) at the first 4 follow-up visits. Marginal structural models controlling for time-invariant and time-varying confounders evaluated the longitudinal relationship between depressive symptoms and PASE z scores.Results: Depressive symptoms were associated with lower PA (β -0.09; 95% CI -0.20 to 0.01) over time, but the relationship was not statistically significant. When including depressive symptoms-by-time interactions, the relationship was nonlinear from the first to fourth follow-up visit: visit 1 = -0.18 (95% CI -0.33 to -0.02), visit 2 = -0.05 (95% CI -0.22 to 0.11), visit 3 = -0.01 (95% CI -0.19 to 0.16), and visit 4 = -0.11 (95% CI -0.29 to 0.08). However, the interaction terms were not statistically significant.Conclusion: Depressive symptoms may contribute to worse self-reported PA levels in persons with KOA. Future research should determine whether lower physical function is a further sequela of decreased PA related to depressive symptoms.","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"505-511"},"PeriodicalIF":3.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045742/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Case of Parvovirus B19-Induced Atlantoaxial Arthritis. 细小病毒b19致寰枢关节关节炎1例。

IF 3.6 2区医学

Journal of Rheumatology Pub Date : 2025-05-01 DOI: 10.3899/jrheum.2024-1293

Cristina Valero-Martínez

引用次数: 0

Patient Perspectives and Clinical Insights Into the Diagnostic Journey From Connective Tissue Disease to Pulmonary Arterial Hypertension. 从结缔组织疾病到肺动脉高压的诊断过程中的患者观点和临床见解。

IF 3.6 2区医学

Journal of Rheumatology Pub Date : 2025-05-01 DOI: 10.3899/jrheum.2024-0613

Kristin B Highland, Rumon Chakravarty, Sylvia Georgi, Michelle Han

{"title":"Patient Perspectives and Clinical Insights Into the Diagnostic Journey From Connective Tissue Disease to Pulmonary Arterial Hypertension.","authors":"Kristin B Highland, Rumon Chakravarty, Sylvia Georgi, Michelle Han","doi":"10.3899/jrheum.2024-0613","DOIUrl":"10.3899/jrheum.2024-0613","url":null,"abstract":"Plain Language SummaryPeople with connective tissue disorders (CTDs), like systemic lupus erythematosus (SLE), mixed CTD, and systemic sclerosis (SSc), are at risk for a lung condition called pulmonary arterial hypertension (PAH). Since PAH gets worse over time if it is not treated, it is important for anyone with PAH to be diagnosed and treated with medication as early as possible. This article describes the experiences of 4 adults who have CTD and PAH, including their journey of being diagnosed with CTD and then PAH, which healthcare providers they saw, and the types of information they were given to learn about their conditions. All 4 people described having a rash as their first symptom of CTD, and said their symptoms got worse over time, which made them see their primary care provider. Two people felt their doctor dismissed their symptoms. Everyone was eventually referred to a rheumatologist or dermatologist and diagnosed with a type of CTD: 1 had SLE, 2 had mixed CTD, and 1 had SSc. Only 1 person was told that having a CTD meant they had a higher risk of getting PAH. It took between 2 and 11 years after their CTD diagnosis to be diagnosed with PAH, all while they were at risk for more intense PAH symptoms. The group recommended better education for doctors and support staff about CTD, so that they are able to screen their patients for PAH, recognize the disease, and quickly refer patients to PAH specialists at accredited pulmonary hypertension centers for further testing.","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"515-519"},"PeriodicalIF":3.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0