{"title":"Parathyroid Adenoma Presenting as Femoral Tumor Lesion in a 27-Year-Old Woman.","authors":"Anastasia Mocritcaia, Pilar Peris","doi":"10.3899/jrheum.2024-0245","DOIUrl":"https://doi.org/10.3899/jrheum.2024-0245","url":null,"abstract":"<p><p>Metabolic bone diseases should be considered in the differential diagnosis of osteolytic lesions. Here, we describe a case of primary hyperparathyroidism with multiple osteolytic lesions that improved following parathyroidectomy.</p>","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yulia Vyzhga, Andrea S Doria, Brian M Feldman, Shirley M Tse
{"title":"Mining for Gems: Early Detection of Calcinosis in Juvenile Dermatomyositis Using Low-Dose Computed Tomography.","authors":"Yulia Vyzhga, Andrea S Doria, Brian M Feldman, Shirley M Tse","doi":"10.3899/jrheum.2024-0594","DOIUrl":"https://doi.org/10.3899/jrheum.2024-0594","url":null,"abstract":"<p><p>Calcinosis, a common complication in juvenile dermatomyositis (JDM), affects up to 40% of patients and can be associated with uncontrolled disease activity and morbidity.<sup>1</sup>A 9-year-old female with a 17-month history of JDM presented with worsened bilateral knee pain.</p>","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating and Refining Strategies for Rheumatoid Arthritis Prevention in First Nations Communities.","authors":"Sijia Liu, Ruwei Hu","doi":"10.3899/jrheum.2024-0726","DOIUrl":"https://doi.org/10.3899/jrheum.2024-0726","url":null,"abstract":"<p><p>We read the article entitled \"The Impact of Rheumatoid Arthritis on First Nations and How We Can Work With Communities to Prevent It\" by Hani El-Gabalawy<sup>1</sup> with great interest. This paper discusses the high prevalence of rheumatoid arthritis (RA) among First Nations communities in North America, as well as the adverse results, such as early mortality.</p>","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Drs. El-Gabalawy and O'Neil reply.","authors":"Hani El-Gabalawy, Liam O'Neil","doi":"10.3899/jrheum.2024-0856","DOIUrl":"https://doi.org/10.3899/jrheum.2024-0856","url":null,"abstract":"<p><p>We would like to thank Drs. Liu and Hu<sup>1</sup> for their thoughtful comments regarding our recent publication.<sup>2</sup> In response to the points made in their letter, we would like to make a few comments.</p>","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Masataka Kuwana, Naoko Wakasugi, Tetsuji Hashida, Satoshi Uno, Takafumi Suda
{"title":"Update on Tacrolimus in Patients With Interstitial Pneumonia Associated With Polymyositis or Dermatomyositis: 3-Year Postmarketing Surveillance Follow-Up in Japan.","authors":"Masataka Kuwana, Naoko Wakasugi, Tetsuji Hashida, Satoshi Uno, Takafumi Suda","doi":"10.3899/jrheum.2024-0379","DOIUrl":"https://doi.org/10.3899/jrheum.2024-0379","url":null,"abstract":"<p><p>In 2013, tacrolimus was approved in Japan for the treatment of interstitial lung disease (ILD) in patients with polymyositis (PM)/dermatomyositis (DM).<sup>1</sup> Subsequently, Kuwana et al<sup>2</sup> reported the 2-year interim prospective results of a postmarketing surveillance study, which found that tacrolimus-containing immunosuppressive regimens were well tolerated in patients with PM/DM-associated ILD.<sup>2</sup>.</p>","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clustering Methods in Rheumatic and Musculoskeletal Disease Research: An Educational Guide to Best Research Practices.","authors":"Samantha Chin, Jamie E Collins","doi":"10.3899/jrheum.2024-0519","DOIUrl":"10.3899/jrheum.2024-0519","url":null,"abstract":"<p><p>Clinical manifestations and disease progression often exhibit significant variability among patients with rheumatic diseases, complicating diagnosis and treatment strategies. A better understanding of disease heterogeneity may allow for personalized treatment strategies. Cluster analysis is a class of statistical methods that aims to identify subgroups or patterns within a dataset. Cluster analysis is a type of unsupervised learning, meaning there are no outcomes or labels to guide the analysis (ie, there is no ground truth). This makes it difficult to assess the accuracy or validity of the identified clusters, and these methods therefore require thoughtful planning and careful interpretation. Here, we provide a high-level overview of clustering, including different types of clustering methods and important considerations when undertaking clustering, and review some examples from the rheumatology literature.</p>","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brittany N Weber, Dana Weisenfeld, Mary Jeffway, Feng Liu, Gregory McDermott, Jonathan Coblyn, Michael E Weinblatt, Nancy Shadick, Marcelo Di Carli, Katherine P Liao
{"title":"The Association Between High-Sensitivity Cardiac Troponin T and Major Adverse Cardiovascular Events in Rheumatoid Arthritis.","authors":"Brittany N Weber, Dana Weisenfeld, Mary Jeffway, Feng Liu, Gregory McDermott, Jonathan Coblyn, Michael E Weinblatt, Nancy Shadick, Marcelo Di Carli, Katherine P Liao","doi":"10.3899/jrheum.2024-0168","DOIUrl":"10.3899/jrheum.2024-0168","url":null,"abstract":"","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141328052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jordan E Roberts, Anna Faino, Mersine A Bryan, Jonathan D Cogen, Esi M Morgan
{"title":"Hospitalization and Mortality Due to Infection Among Children and Adolescents With Systemic Lupus Erythematosus in the United States.","authors":"Jordan E Roberts, Anna Faino, Mersine A Bryan, Jonathan D Cogen, Esi M Morgan","doi":"10.3899/jrheum.2023-1219","DOIUrl":"10.3899/jrheum.2023-1219","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to determine the frequency and types of infections in hospitalized children with childhood-onset systemic lupus erythematosus (cSLE), and to identify risk factors for intensive care unit (ICU) admission and mortality.</p><p><strong>Methods: </strong>We conducted a retrospective study of youth aged 2 to 21 years using International Classification of Diseases (ICD) codes for SLE assigned during admission to a hospital participating in the Pediatric Health Information System, a database of United States children's hospitals, from 2009 to 2021. Generalized linear mixed effects models were used to identify risk factors for ICU admission and mortality among children hospitalized with infection.</p><p><strong>Results: </strong>We identified 8588 children with cSLE and ≥ 1 hospitalization. Among this cohort, there were 26,269 hospitalizations, of which 13% had codes for infections, a proportion that increased over time (<i>P</i> = 0.04). Bacterial pneumonia was the most common hospitalized infection. In-hospital mortality occurred in 0.4% (n = 103) of cSLE hospitalizations for any indication and 2% of hospitalizations for infection (n = 60). The highest mortality rates occurred with <i>Pneumocystis jirovecii</i> pneumonia (21%) and other fungal infections (21%). Lupus nephritis (LN) and endstage renal disease (ESRD) were associated with increased odds of ICU admission (odds ratio [OR] 1.47 [95% CI 1.2-1.8] and OR 2.40 [95% CI 1.7-3.4]) among children admitted for serious infection. ESRD was associated with higher mortality (OR 2.34 [95% CI 1.1-4.9]).</p><p><strong>Conclusion: </strong>Hospitalizations with ICD codes for infection comprised a small proportion of cSLE admissions but accounted for the majority of mortality. The proportion of hospitalizations for infection increased over time. LN and ESRD were risk factors for poor outcomes.</p>","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140337427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Telerheumatology Shared-Care Model: Leveraging the Expertise of an Advanced Clinician Practitioner in Arthritis Care (ACPAC)-Trained Extended Role Practitioner in Rural-Remote Ontario.","authors":"Amanda Steiman, Taucha Inrig, Katie Lundon, Jocelyne Murdoch, Rachel Shupak","doi":"10.3899/jrheum.2023-1143","DOIUrl":"10.3899/jrheum.2023-1143","url":null,"abstract":"<p><strong>Objective: </strong>A shortage of rheumatologists has led to gaps in inflammatory arthritis (IA) care in Canada. Amplified in rural-remote communities, the number of rheumatologists practicing rurally has not been meaningfully increased, and alternate care strategies must be adopted. In this retrospective chart review, we describe the impact of a shared-care telerheumatology model using a community-embedded Advanced Clinician Practitioner in Arthritis Care (ACPAC)-extended role practitioner (ERP) and an urban-based rheumatologist.</p><p><strong>Methods: </strong>A rheumatologist and an ACPAC-ERP established a monthly half-day hub-and-spoke-telerheumatology clinic to care for patients with suspected IA, triaged by the ACPAC-ERP. Comprehensive initial assessments were conducted in-person by the ACPAC-ERP (spoke); investigations were completed prior to the telerheumatology visit. Subsequent collaborative visits occurred with the rheumatologist (hub) attending virtually. Retrospective analysis of demographics, time-to-key care indices, patient-reported outcomes, clinical data, and estimated travel savings was performed.</p><p><strong>Results: </strong>Data from 124 patients seen between January 2013 and January 2022 were collected; 98% (n = 494/504 visits) were virtual. The average age of patients at first visit was 55.6 years, and 75.8% were female. IA/connective tissue disease (CTD) was confirmed in 65% of patients. Mean time from primary care referral to ACPAC-ERP assessment was 52.5 days, and mean time from ACPAC-ERP assessment to the telerheumatology visit was 64.5 days. An estimated 493,470 km of patient-related travel was avoided.</p><p><strong>Conclusion: </strong>An ACPAC-ERP (spoke) and rheumatologist (hub) telerheumatology model of care assessing and managing patients with suspected IA in rural-remote Ontario was described. This model can be leveraged to increase capacity by delivering comprehensive virtual rheumatologic care in underserved communities.</p>","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manasi M Mittinty, Murthy N Mittinty, Rachelle Buchbinder, Marissa Lassere, Vibhasha Chand, Samuel Whittle, Lyn March, Catherine Hill
{"title":"Interpersonal Process of Dyadic Coping in Rheumatoid Arthritis: A Perspective From the Australian Rheumatology Association Database.","authors":"Manasi M Mittinty, Murthy N Mittinty, Rachelle Buchbinder, Marissa Lassere, Vibhasha Chand, Samuel Whittle, Lyn March, Catherine Hill","doi":"10.3899/jrheum.2023-0664","DOIUrl":"10.3899/jrheum.2023-0664","url":null,"abstract":"<p><strong>Objective: </strong>Dyadic coping, the process of coping that transpires between couples challenged by one partner's illness, is an important predictor of disease adjustment and patient well-being. However, the extent of dyadic coping in rheumatoid arthritis (RA) remains unclear. This study examines the effect of dyadic coping on psychological distress and relationship quality from the perspectives of both participants with RA and their spouses.</p><p><strong>Methods: </strong>Participants and their spouses were invited to participate in an online survey study if they were aged ≥ 18 years and had lived together for more than a year. The survey included the Chronic Pain Grade Scale, Dyadic Coping Inventory, Depression Anxiety Stress Scale, and Dyadic Adjustment Scale. Participants and spouses completed the survey independently. The actor-partner interdependence model was used to analyze the dyadic data.</p><p><strong>Results: </strong>One hundred sixty-three couples participated. Our findings showed that participants who reported higher supportive dyadic coping reported lower depression, anxiety, and stress, and higher relationship quality, whereas participants who reported higher negative dyadic coping reported higher depression, anxiety, and stress, and lower relationship quality. Spouses who reported higher supportive dyadic coping reported higher relationship quality, but no effect on depression, anxiety, and stress was observed. In contrast, spouses who reported higher negative dyadic coping reported higher levels of depression, anxiety, and stress, and lower relationship quality.</p><p><strong>Conclusion: </strong>Participants' and spouses' perceptions of supportive and negative dyadic coping closely influenced their psychological distress and relationship quality. Further, having a partner with RA also seemed to affect the spouse, especially when there was a negative dyadic coping pattern.</p>","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}