Amanda Steiman, Katie Lundon, Laura Passalent, Leslie Soever, Deborah M Levy, Christopher Nielsen, Rachel Shupak
{"title":"What's in a Name: The Value of Defining Core Competencies for Extended Role Practitioners in Arthritis Care.","authors":"Amanda Steiman, Katie Lundon, Laura Passalent, Leslie Soever, Deborah M Levy, Christopher Nielsen, Rachel Shupak","doi":"10.3899/jrheum.2024-0995","DOIUrl":"10.3899/jrheum.2024-0995","url":null,"abstract":"","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"194"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142840087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Early Course of Radiographic Progression in Axial Spondyloarthritis: Have We Missed Something?","authors":"Jürgen Braun","doi":"10.3899/jrheum.2024-0807","DOIUrl":"10.3899/jrheum.2024-0807","url":null,"abstract":"","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"116-118"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tiphaine Goulenok, Arthur Mageau, Chrystelle François, Claire Dossier, Eric Hachulla, Thomas Papo, Karim Sacré
{"title":"Knowledge About Human Papillomavirus Among Patients With Immune-Mediated Inflammatory Diseases.","authors":"Tiphaine Goulenok, Arthur Mageau, Chrystelle François, Claire Dossier, Eric Hachulla, Thomas Papo, Karim Sacré","doi":"10.3899/jrheum.2024-0959","DOIUrl":"10.3899/jrheum.2024-0959","url":null,"abstract":"","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"192-194"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142840050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gelsomina Alle, Clementina Lopez-Medina, Stefan Siebert, Frédéric Lavie, Wim Noel, Josef S Smolen, Laure Gossec
{"title":"Patient Profiles in Randomized Controlled Trials Versus a Real-World Study in Psoriatic Arthritis: Scoping Review and Metaanalysis.","authors":"Gelsomina Alle, Clementina Lopez-Medina, Stefan Siebert, Frédéric Lavie, Wim Noel, Josef S Smolen, Laure Gossec","doi":"10.3899/jrheum.2024-0653","DOIUrl":"10.3899/jrheum.2024-0653","url":null,"abstract":"<p><strong>Objective: </strong>Patients with psoriatic arthritis (PsA) in randomized controlled trials (RCTs) may not reflect patients with PsA in clinical practice. Our objective was to perform a metaanalysis comparing the characteristics of patients with PsA in RCTs of biologic disease-modifying antirheumatic drugs (bDMARDs) to patient profiles in a real-world study.</p><p><strong>Methods: </strong>Data sources included (1) a scoping literature review of phase III RCTs of bDMARDs in PsA published between 2015 and 2020, and (2) an international observational study of patients with PsA starting a bDMARD enrolled between 2015 and 2018 (PsABio; ClinicalTrials.gov: NCT02627768). Data collected at baseline included swollen and tender joint counts (SJC/TJC), presence of enthesitis, skin involvement (body surface area [BSA]), C-reactive protein (CRP), physician global assessment (PGA), and patient-reported outcomes (PROs; Health Assessment Questionnaire [HAQ], pain). Univariate random effects metaanalysis was conducted to calculate pooled means and proportions.</p><p><strong>Results: </strong>Overall, 5654 patients from 10 RCTs were compared to 930 PsABio patients. Demographic data were similar. SJC/TJC were higher in RCTs than in PsABio (pooled means: 11.8/21.5 vs 5.7/11.9), and enthesitis was more frequent in RCTs (64.7% vs 48.2%), as were patients with a BSA ≥ 3% (62.2% vs 54%). PGA was higher in RCTs (59.7 vs 54.1). In contrast, PROs were similar, whereas CRP was significantly higher in PsABio (1.4 vs 1.1 mg/dL).</p><p><strong>Conclusion: </strong>Patients with PsA starting a bDMARD in RCTs had highly active disease and a high patient-reported disease burden. In contrast, PsABio real-world patients starting a bDMARD had lower SJC/TJC, skin involvement, and PGA, but presented with similar patient-reported disease burden. The extrapolation of RCT data in clinical practice should take these elements into account.</p>","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"138-144"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142640138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caroline Mazeda, Sofia Azevedo, Sérgio Sousa, Anabela Barcelos
{"title":"Not Everything is Osteoporosis: Multiple Low-Impact Fractures in an Adult Female Patient.","authors":"Caroline Mazeda, Sofia Azevedo, Sérgio Sousa, Anabela Barcelos","doi":"10.3899/jrheum.2024-0672","DOIUrl":"https://doi.org/10.3899/jrheum.2024-0672","url":null,"abstract":"","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Boutonniere Deformity and Piano Key Sign Depicted in a 12th-Century Chinese Painting.","authors":"Qiman Liu, Haojie Xu","doi":"10.3899/jrheum.2024-1286","DOIUrl":"https://doi.org/10.3899/jrheum.2024-1286","url":null,"abstract":"","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahmud Omar, Reem Agbareia, Eyal Klang, Mohammaed E Naffaa
{"title":"Large Language Models in Rheumatologic Diagnosis: A Multimodal Performance Analysis.","authors":"Mahmud Omar, Reem Agbareia, Eyal Klang, Mohammaed E Naffaa","doi":"10.3899/jrheum.2024-0975","DOIUrl":"10.3899/jrheum.2024-0975","url":null,"abstract":"","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"187-188"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142640137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of Single-Arm Observational Data for Causal Inference: The Case of GLA:D for Hip and Knee Osteoarthritis.","authors":"Daniel L Riddle, Ian A Harris, Robin Christensen","doi":"10.3899/jrheum.2024-0880","DOIUrl":"10.3899/jrheum.2024-0880","url":null,"abstract":"","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"196-197"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142840064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Krista Hammaker, Haomin Hu, Maureen Laffoon, Leigh A Freno, Robert Lafyatis, Yongseok Park, Robyn T Domsic
{"title":"Association of the Apollo Wearable With Fatigue, Raynaud Phenomenon, and Quality of Life in Patients With Systemic Sclerosis: A Pilot Study.","authors":"Krista Hammaker, Haomin Hu, Maureen Laffoon, Leigh A Freno, Robert Lafyatis, Yongseok Park, Robyn T Domsic","doi":"10.3899/jrheum.2024-0551","DOIUrl":"10.3899/jrheum.2024-0551","url":null,"abstract":"<p><strong>Objective: </strong>In patients with systemic sclerosis (SSc), fatigue is the highest-ranked symptom affecting quality of life (QOL), followed by Raynaud phenomenon (RP). We report results from a pilot study of the Apollo wearable device in patients with SSc.</p><p><strong>Methods: </strong>Twenty-five adult participants with SSc, moderate fatigue, and RP were enrolled. Participants completed a 4-week intervention, during which they wore the Apollo device daily for a minimum of 15 minutes. The primary outcome was change on the Patient Reported Outcomes Measurement Information System Fatigue 13a (PROMIS Fatigue) at 4 weeks.</p><p><strong>Results: </strong>After 4 weeks of using the Apollo wearable, participants reported less fatigue on the PROMIS Fatigue (<i>P</i> < 0.001) scale. The average daily number of RP attacks declined (<i>P</i> = 0.007), as did the Raynaud Condition Score (<i>P</i> = 0.007) after 4 weeks of use. Average device usage (2.87 hours/day) far exceeded the requested time, and no adverse events occurred. The PROMIS-29 subscores assessment demonstrated QOL improvement in physical function (<i>P</i> = 0.01), depression (<i>P</i> = 0.03), fatigue (<i>P</i> = 0.01), sleep disturbance (<i>P</i> = 0.002), and ability to participate in social roles and activities (<i>P</i> < 0.001). Significant improvements were also noted for depression (<i>P</i> = 0.004) and disability (<i>P</i> < 0.05) measures.</p><p><strong>Conclusion: </strong>Use of the Apollo wearable for 4 weeks was associated with improvement in fatigue and RP symptoms in patients with SSc, with improved QOL measures, lower depression scores, and improved disability measures. Future studies should further test the efficacy of the Apollo wearable in these domains and QOL of patients with SSc. (ClinicalTrials.gov: NCT04854850).</p>","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"158-164"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}