Laura C Cappelli, Rebecca Fitzpatrick, Clifton O Bingham, Ami A Shah
{"title":"Dr. Cappelli et al reply.","authors":"Laura C Cappelli, Rebecca Fitzpatrick, Clifton O Bingham, Ami A Shah","doi":"10.3899/jrheum.2026-0554","DOIUrl":"https://doi.org/10.3899/jrheum.2026-0554","url":null,"abstract":"","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148457416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dafna D Gladman, Wilson Bautista-Molano, Denis Poddubnyy, William Tillett, Maarten de Wit, Alice B Gottlieb
{"title":"Prologue: Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) 2025 Annual Meeting.","authors":"Dafna D Gladman, Wilson Bautista-Molano, Denis Poddubnyy, William Tillett, Maarten de Wit, Alice B Gottlieb","doi":"10.3899/jrheum.2026-0590","DOIUrl":"https://doi.org/10.3899/jrheum.2026-0590","url":null,"abstract":"<p><p>The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) 2025 annual meeting was held from July 10 to 12, 2025, in Bogotá, Colombia. It was attended by 206 rheumatologists, dermatologists, trainees, patient research partners, representatives of patient organizations, industry partners, and others. Here we provide an overview of the workshops and symposia featured at the GRAPPA 2025 annual meeting and introduce the manuscripts published together in this supplement as a meeting report.</p>","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148406745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Disseminated Nocardiosis in an Elderly Patient Receiving Long-Term Glucocorticoid Therapy for Polymyalgia Rheumatica.","authors":"Yuya Sato, Yasuhito Hamaguchi, Taketo Kubo, Takashi Matsushita","doi":"10.3899/jrheum.2025-1082","DOIUrl":"10.3899/jrheum.2025-1082","url":null,"abstract":"","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"828-829"},"PeriodicalIF":3.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Crohn Disease, Takayasu Arteritis, and Thrombophlebitis: Is There Underlying Behçet Disease? Genetic Clues and the Complex Role of Infliximab.","authors":"Jiang Yunxia, Dai Xiaoliang","doi":"10.3899/jrheum.2025-1182","DOIUrl":"10.3899/jrheum.2025-1182","url":null,"abstract":"","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"833-834"},"PeriodicalIF":3.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147823102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Classification of Nonsystemic Juvenile Idiopathic Arthritis Using the Provisional Paediatric Rheumatology International Trials Organisation Criteria.","authors":"Mehmet Yildiz, Elif Kilic Konte, Esma Aslan, Nergis Akay, Hakan Demir, Aybuke Gunalp, Fatih Haslak, Umit Gul, Ece Aslan, Sezgin Sahin, Amra Adrovic, Kenan Barut, Ozgur Kasapcopur","doi":"10.3899/jrheum.2025-0551","DOIUrl":"10.3899/jrheum.2025-0551","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to retrospectively evaluate the provisional Paediatric Rheumatology International Trials Organisation (PRINTO) criteria in patients with juvenile idiopathic arthritis (JIA) classified according to the International League of Associations for Rheumatology (ILAR) criteria.</p><p><strong>Methods: </strong>This retrospective cohort study was conducted at a single tertiary pediatric rheumatology center. In total, 310 patients with nonsystemic JIA were classified according to both ILAR and provisional PRINTO criteria. Demographic, clinical, and laboratory features were recorded, and the distribution of JIA categories under both classification systems was analyzed.</p><p><strong>Results: </strong>The mean age at study enrollment was 169.8 (SD 59.2) months. Using ILAR criteria, 136 patients (43.9%) were categorized as having oligoarticular JIA, 73 (23.5%) enthesitis-related arthritis, 34 (11%) rheumatoid factor (RF)-negative polyarticular JIA, 12 (3.9%) psoriatic arthritis (PsA), 7 (2.3%) RF-positive polyarticular JIA, and 48 (15.5%) undifferentiated JIA. The provisional PRINTO criteria classified 107 (34.5%) patients with early-onset antinuclear antibody-positive JIA, 93 (30%) other JIA, 88 (28.4%) enthesitis/spondylitis-related JIA, 17 (5.5%) RF-positive JIA, and 5 (1.6%) unclassified JIA. The other JIA category included 93 patients, consisting of those with oligoarticular JIA (54.8%), RF-negative polyarticular JIA (21.5%), undifferentiated JIA (11.8%), enthesitis-related arthritis (6.5%), and PsA (5.4%) under the ILAR classification system.</p><p><strong>Conclusion: </strong>The provisional PRINTO criteria successfully reclassified a substantial proportion of previously undifferentiated JIA cases, improving diagnostic categorization by addressing some ILAR classification limitations. However, the high number of patients in the other JIA group highlights a potential limitation of the new system, warranting further investigation.</p>","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"800-807"},"PeriodicalIF":3.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does the ACR/EULAR Total Improvement Score Reflect How Individuals With Autoimmune Inflammatory Myopathies Feel and Function?","authors":"Valérie Leclair, Claudie Berger, Maude Bouchard-Marmen, Josiane Bourré-Tessier, Océane Landon-Cardinal, Marie Hudson","doi":"10.3899/jrheum.2026-0046","DOIUrl":"10.3899/jrheum.2026-0046","url":null,"abstract":"<p><strong>Objective: </strong>Little is known as to whether the American College of Rheumatology/European Alliance of Associations for Rheumatology Total Improvement Score (TIS) reflects how patients with autoimmune inflammatory myopathies (AIM) feel and function. We assessed the associations between TIS and changes in the scores of a wide range of patient-reported outcomes (PROs).</p><p><strong>Methods: </strong>Adult patients with AIM and active disease at baseline who completed a 1-year follow-up visit were identified from a research cohort. PROs included a numerical rating scale for pain, the Functional Assessment of Chronic Illness Therapy - Fatigue (FACIT-Fatigue) scale, the Patient-Reported Outcomes Measurement Information System (PROMIS) Short Form v1.0 Fatigue 8a, the 9-item Patient Health Questionnaire (PHQ-9), and the 36-Item Short Form Health Survey (SF-36) physical and mental component summary scores (PCS and MCS, respectively). Multivariable linear regression models were generated to determine the absolute change in PRO scores for each 20-unit increase in absolute TIS.</p><p><strong>Results: </strong>We identified 65 patients with active disease for whom TIS could be calculated. At 1 year, 40% showed no improvement, 34% achieved minimal improvement, and 26% achieved moderate improvement. In adjusted models, increase in absolute TIS was associated with statistically significant improvements in pain, PROMIS-Fatigue, FACIT-Fatigue, and SF-36 PCS scores. For FACIT-Fatigue, a significant interaction was identified between age and TIS. In stratified analyses, only patients with shorter disease duration significantly improved in pain and FACIT-Fatigue scores.</p><p><strong>Conclusion: </strong>The findings of this cohort study support the use of the TIS in AIM research but also highlight potential limitations in its ability to capture outcomes across the broader AIM spectrum, particularly among older individuals and those with longer disease duration.</p>","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148260281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Junjie Wang, Haonan Fang, Yining Wang, Xing Xing, Guoqi Cai
{"title":"Association of Periarticular Subchondral Bone Mineral Density With the Presence and Progression of Knee Pain: Data From the Osteoarthritis Initiative.","authors":"Junjie Wang, Haonan Fang, Yining Wang, Xing Xing, Guoqi Cai","doi":"10.3899/jrheum.2025-1000","DOIUrl":"10.3899/jrheum.2025-1000","url":null,"abstract":"<p><strong>Objective: </strong>To explore the association between periarticular subchondral bone mineral density (sBMD) and the presence and progression of osteoarthritis (OA) knee pain.</p><p><strong>Methods: </strong>Participants were recruited from the Osteoarthritis Initiative (OAI). Tibial sBMD at medial and lateral compartments was measured by dual-energy x-ray absorptiometry at 30 or 36 months (baseline) and reassessed at 48 months. Knee pain was assessed using the Western Ontario and McMaster Universities Arthritis Index (WOMAC) pain subscale (range 0-20, with a higher score indicating greater pain) through month 108. Baseline knee pain was categorized as low/no or high (pain score < 5 vs ≥ 5). Pain progression was defined as an increase in WOMAC pain score of ≥ 2 in at least 3 of the 6 follow-up visits. Logistic regression with generalized estimating equations was used to assess associations between sBMD (per SD increase) and knee pain, accounting for within-participant correlation between knees.</p><p><strong>Results: </strong>Of 594 participants (mean age 64.1 years; 50.5% male; 1137 knees), 31.6% of knees exhibited higher pain at baseline, and 37.4% demonstrated pain progression during follow-up. Higher medial sBMD and medial-to-lateral sBMD ratio were associated with the progression of knee pain (medial sBMD: odds ratio [OR] 1.50; 95% CI 1.25-1.81; <i>P</i> < 0.001; medial-to-lateral ratio: OR 1.29; 95% CI 1.11-1.49; <i>P</i> = 0.001). Medial-to-lateral sBMD ratio was also associated with the presence of knee pain (OR 1.21; 95% CI 1.05-1.40; <i>P</i> = 0.01).</p><p><strong>Conclusion: </strong>Higher medial-to-lateral sBMD ratio was associated with both the presence and progression of knee pain, suggesting that relative subchondral bone distribution may better capture biomechanical loading imbalance related to symptomatic OA than absolute sBMD alone.</p>","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"808-815"},"PeriodicalIF":3.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147949982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicolas Richard, Jordi Pardo Pardo, Reza Mirza, Sibel Z Aydin, Louis Bessette, Dianne Mosher, Tristan Boyd, Jon Chan, Lihi Eder, Laura Passalent, Elie Karam, Bindu Nair, Glen S Hazlewood, Shirley M L Tse, Dax G Rumsey, Michel Zummer, Nigil Haroon, Robert Inman, Dafna D Gladman, Sherry Rohekar
{"title":"Canadian Rheumatology Association/Spondyloarthritis Research Consortium of Canada Living Treatment Recommendations for the Management of Axial Spondyloarthritis: Update #1.","authors":"Nicolas Richard, Jordi Pardo Pardo, Reza Mirza, Sibel Z Aydin, Louis Bessette, Dianne Mosher, Tristan Boyd, Jon Chan, Lihi Eder, Laura Passalent, Elie Karam, Bindu Nair, Glen S Hazlewood, Shirley M L Tse, Dax G Rumsey, Michel Zummer, Nigil Haroon, Robert Inman, Dafna D Gladman, Sherry Rohekar","doi":"10.3899/jrheum.2026-0227","DOIUrl":"10.3899/jrheum.2026-0227","url":null,"abstract":"","PeriodicalId":50064,"journal":{"name":"Journal of Rheumatology","volume":" ","pages":"830-832"},"PeriodicalIF":3.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147595858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}