Journal of the American Society of Echocardiography最新文献

{"title":"Reduced Right Ventricular Size and Function in Adolescents and Adults Born Preterm.","authors":"Zachary W Blair, Alvin Chandra, Gregory P Barton, Nataly Sanchez Solano, Jarett D Berry, Kara N Goss","doi":"10.1016/j.echo.2025.04.007","DOIUrl":"10.1016/j.echo.2025.04.007","url":null,"abstract":"<p><strong>Background: </strong>Adults born premature have smaller cardiac chamber sizes, and some develop right ventricular (RV) dysfunction. Risk factors for RV dysfunction into adulthood remain unclear. The aim of this study was to investigate right-sided cardiac structure and function among adolescents and adults born preterm.</p><p><strong>Methods: </strong>Participants born moderately to extremely premature (≤32 weeks) or at very low birth weight (<1500 g) aged 12 to 40 years were recruited from the Parkland Health Neonatal Intensive Care Unit Registry. Healthy term-born similarly aged participants were recruited from Dallas County. Study visits included anthropometric measurements, a cardiopulmonary examination, and echocardiography. Multivariable linear regression models were used to determine the main effect of prematurity (yes or no) and gestational age on right atrial and RV structure and function after adjusting for age, sex, body surface area, and birth weight Z scores.</p><p><strong>Results: </strong>Preterm participants (n = 107) had a mean gestational age of 29.3 ± 2.7 weeks and a mean birth weight of 1,320 ± 398 g. Compared with term participants (n = 48), echocardiography demonstrated smaller right atrial volume and RV area. Tricuspid annular plane systolic excursion, tissue Doppler imaging systolic tricuspid annular peak velocity (RV s'), and early diastolic velocity (RV e') were lower in preterm participants, with a significant dose response with gestational age and in the absence of overt pulmonary hypertension.</p><p><strong>Conclusions: </strong>Right-sided chamber sizes were smaller, with reduced tricuspid annular plane systolic excursion, RV s', and RV e' in adolescents and adults born premature, with a clear association with gestational age. Reduced RV function in the absence of overt pulmonary hypertension suggests preterm birth imparts an independent insult on the developing RV with lifetime implications.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical Adaptation of the Right Ventricle to Secondary Tricuspid Regurgitation, and Its Association with Patients' Outcomes.","authors":"Edith Liliana Posada-Martinez, Lissa Sugeng","doi":"10.1016/j.echo.2025.04.006","DOIUrl":"https://doi.org/10.1016/j.echo.2025.04.006","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiographic Estimate of Pulmonary Capillary Wedge Pressure Improves Outcome Prediction in Heart Failure Patients With Reduced and Mildly Reduced Ejection Fraction.","authors":"Lorenzo Bazan, Francesco Gentile, Paolo Sciarrone, Francesco Buoncristiani, Giorgia Panichella, Simone Gasparini, Claudia Taddei, Elisa Poggianti, Iacopo Fabiani, Christina Petersen, Giuseppe Emanuele Lio, Patrizio Lancellotti, Claudio Passino, Michele Emdin, Vladislav Chubuchny, Alberto Giannoni","doi":"10.1016/j.echo.2025.04.005","DOIUrl":"10.1016/j.echo.2025.04.005","url":null,"abstract":"<p><strong>Background: </strong>An echocardiographic algorithm to estimate pulmonary capillary wedge pressure (ePCWP) and pulmonary vascular resistance (ePVR) has been recently validated versus right heart catheterization.</p><p><strong>Objective: </strong>To assess the prognostic significance of these measures in heart failure (HF) patients with reduced and mildly reduced ejection fraction.</p><p><strong>Methods: </strong>Consecutive outpatients with HF and left ventricular ejection fraction (LVEF) <50% undergoing echocardiography were selected and followed up for the composite end point of all-cause death or HF hospitalization.</p><p><strong>Results: </strong>Out of 2,214 patients (71 ± 12 years, 76% males, LVEF 35% ± 9%), ePCWP (16 ± 6 mm Hg) was elevated (>15 mm Hg) in 52% of cases and ePVR (1.7 ± 0.7 Wood units) was elevated (>2 Wood units) in 25% of cases. Patients with increased ePCWP were older and had a higher New York Heart Association class, more pronounced cardiac remodeling, systolic/diastolic dysfunction, and neurohormonal activation, particularly when ePVR was also elevated (P < .001). Over a median follow-up of 33 (17-48) months, both measures stratified patients for the risk of the primary end point (log-rank 151 for ePCWP and 60 for ePVR; P < .001). At adjusted regression analysis, ePCWP (hazard ratio for 1 mm Hg increase 1.03 [95% CI, 1.01-1.04]; P < .001) but not ePVR (P = .07) predicted the primary end point, even in patients with atrial fibrillation (P = .019), outperforming current diastolic dysfunction grading (P < .001) and both E/e' and left atrial volume index (P < .001). The addition of ePCWP to a multivariable prognostic model improved the accuracy of risk prediction (P < .001).</p><p><strong>Conclusion: </strong>The echocardiographic estimates of PCWP retained clinical and prognostic significance in a large contemporary cohort of patients with chronic HF and LVEF <50%.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indexing Tricuspid Annular Systolic Plane Excursion to Right Ventricular Length as a Surrogate of Right Ventricular Free Wall Strain.","authors":"Philippe Unger, Michaël Rietz, Xavier Galloo","doi":"10.1016/j.echo.2025.04.003","DOIUrl":"https://doi.org/10.1016/j.echo.2025.04.003","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep Learning-Based Detection and Severity Assessment of Bicuspid Aortic Valve Stenosis.","authors":"Jiesuck Park, Jiyeon Kim, Jaeik Jeon, Yeonyee E Yoon, Yeonggul Jang, Hyunseok Jeong, Seung-Ah Lee, Hong-Mi Choi, In-Chang Hwang, Goo-Yeong Cho, Hyuk-Jae Chang","doi":"10.1016/j.echo.2025.04.002","DOIUrl":"https://doi.org/10.1016/j.echo.2025.04.002","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Validation of a Novel Deep Learning Model to Predict Pharmacologic Closure of Patent Ductus Arteriosus in Premature Infants.","authors":"Puneet Sharma, Addison Gearhart, Guangze Luo, Anil Palepu, Cindy Wang, Joshua Mayourian, Kristyn Beam, Fotios Spyropoulos, Andrew J Powell, Philip Levy, Andrew Beam","doi":"10.1016/j.echo.2025.03.018","DOIUrl":"https://doi.org/10.1016/j.echo.2025.03.018","url":null,"abstract":"<p><strong>Background: </strong>Patent ductus arteriosus (PDA) is associated with significant morbidity and mortality in preterm infants. Although pharmacotherapy can be effective, it is difficult to predict whether a patient will respond, leading to delays in care. Machine learning has emerged as a powerful tool to interpret clinical data to predict clinical outcomes but has not yet been applied to this question. The aim of this study was to train and validate a novel deep learning model to predict the likelihood of PDA closure after an initial course of pharmacotherapy in preterm infants.</p><p><strong>Methods: </strong>A retrospective cohort of 174 preterm infants who received pharmacologic treatment for PDA was identified. After collecting relevant perinatal data and pretreatment echocardiograms, the subjects were randomized into training and validation sets in a 70:30 split. Two distinct convolutional neural networks (CNN) were trained, one based on echocardiograms alone and the other on both echocardiograms and perinatal data. The performance of the CNNs was compared against controls of random forest and logistic regression models trained on perinatal data alone.</p><p><strong>Results: </strong>The rate of PDA closure after an initial course of pharmacotherapy was 60% in this cohort. The 174 echocardiograms collected for all subjects included 1,926 clips. A total of 121 infants (1,387 clips) were successfully randomized into the training set and 53 (539 clips) into the validation set. The multimodal CNN had an area under the curve (AUC) of 0.82, outperforming the imaging-only model (AUC = 0.66). Additionally, the multimodal CNN outperformed logistic regression (AUC = 0.66) and random forest (AUC = 0.74) models.</p><p><strong>Conclusions: </strong>This novel, multimodal CNN shows promise for clinicians, who do not currently have a reliable tool to predict the success of PDA closure after an initial course of pharmacotherapy. This investigation represents the first attempt to use deep learning methodology to predict this outcome.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamic Segmentation of Three-Dimensional Transesophageal Echocardiography Using an Automated Neural Network for Transcatheter Edge-to-Edge Repair.","authors":"Charlotte L Frost, Mahesh Vidula, Ray Hu, Howard C Herrmann, Alison M Pouch, Tiffany Chen","doi":"10.1016/j.echo.2025.04.004","DOIUrl":"10.1016/j.echo.2025.04.004","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging of Left Ventricular Diastolic Function: Do We Need Both Left Atrial Volume and Reservoir Strain?","authors":"Otto A Smiseth, John M Aalen","doi":"10.1016/j.echo.2025.04.001","DOIUrl":"https://doi.org/10.1016/j.echo.2025.04.001","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of an Artificial Intelligence Model to Detect Heart Failure With Preserved Ejection Fraction to Handheld Ultrasound Imaging.","authors":"Jose K James, Geoffrey Huntley, Ayana Z Arystan, Claire Cassianni, Christopher G Scott, Halley Davison, Ashley Akerman, Will Hawkes, Jorge Oliveria, Agis Chartsias, Alberto Gomez, Ross Upton, Patricia A Pellikka","doi":"10.1016/j.echo.2025.03.016","DOIUrl":"https://doi.org/10.1016/j.echo.2025.03.016","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Elusive Nature of “Simple” D-Transposition During Perinatal Transition","authors":"Rajesh Punn MD ,&nbsp;Anita J. Moon-Grady MD","doi":"10.1016/j.echo.2025.02.002","DOIUrl":"10.1016/j.echo.2025.02.002","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 4","pages":"Pages 340-341"},"PeriodicalIF":5.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}