Journal of the American Society of Echocardiography最新文献

{"title":"Optimal Cut Plane for Tricuspid Annular Plane Systolic Excursion Measurement.","authors":"Michito Murayama, Sanae Kaga, Hisao Nishino, Yusuke Yanagi, Mana Goto, Fuka Ando, Shinobu Yokoyama, Marina Yamaguchi, Kazunori Okada, Masahiro Nakabachi, Makoto Kambayashi, Yui Shimono, Kosuke Nakamura, Yoji Tamaki, Suguru Ishizaka, Hiroyuki Iwano, Toshiyuki Nagai, Toshihisa Anzai","doi":"10.1016/j.echo.2024.12.013","DOIUrl":"10.1016/j.echo.2024.12.013","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left Ventricular Elastance With Resting Volumetric Transthoracic Echocardiography Identifies Different Phenotypes in Heart Failure With Preserved Ejection Fraction: A Retrospective Analysis of a Multicenter Prospective Observational Study.","authors":"Yi Wang, Quirino Ciampi, Lauro Cortigiani, Angela Zagatina, Ratnasari Padang, Garvan C Kane, Hector R Villarraga, Jesus Peteiro Vazquez, Elena Kalinina, Alla Boshchenko, Tamara Ryabova, Fiore Manganelli, Hugo Rodriguez-Zanella, Jelena Celutkiene, Elisa Merli, Clarissa Borguezan-Daros, Jorge Lowenstein, Rosina Arbucci, Diego M Lowenstein Haber, Sofia Marconi, Pablo M Merlo, Karina Wierzbowska-Drabik, Ayten Safarova, Tatiana Timofeeva, Ariel Saad, Francesca Bursi, Jaroslaw D Kasprzak, Ana Djordjevic-Dikic, Sergio Kobal, Dimitrios Soulis, Nicola Gaibazzi, Nithima Chaowalit Ratanasit, Rodolfo Citro, Albert Varga, Marco Fabio Costantino, Fausto Rigo, Aleksandra Nikolic, Giovanni Benfari, Miguel Amor, Ana Cristina Camarozano, Rosangela Cocchia, Attila Palinkas, Antonello D'Andrea, Miodrag Ostojic, Tamara Kovačević Preradović, Iana Simova, Federica Re, Paolo Colonna, Maria Grazia D'Alfonso, Fabio Mori, Claudio Dodi, Filipa Xavier Valente, Giovanni Tripepi, Lixue Yin, Mauro Pepi, Scipione Carerj, Patricia A Pellikka, Eugenio Picano","doi":"10.1016/j.echo.2024.12.012","DOIUrl":"10.1016/j.echo.2024.12.012","url":null,"abstract":"<p><strong>Background: </strong>Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous entity including different phenotypes of near normal, normal, and supernormal left ventricular (LV) function. The aim of this study was to assess the value of resting LV elastance (also known as force) using transthoracic echocardiography to identify HFpEF phenotypes.</p><p><strong>Methods: </strong>In a prospective, observational, multicenter study, 2,380 patients with HFpEF were recruited from July 2016 to May 2024. Systolic blood pressure (SBP) was measured. LV end-diastolic volume (LVEDV), LV end-systolic volume (LVESV), LV ejection fraction, force (SBP/LVESV), stroke volume (SV), arterial elastance, ventricular-arterial coupling, and left atrial volume index were assessed. Global longitudinal strain was available in 1,164 patients (48.9%). Six hundred eighty patients finished follow-up with a composite endpoint of major adverse cardiac events (MACEs). Patients were divided into three groups: group 1, low force (<25th percentile, <3.24 mm Hg/mL); group 2, intermediate force (≥25th percentile and ≤75th percentile, 3.24-5.48 mm Hg/mL); and group 3, high force (>75th percentile, >5.48 mmHg/mL).</p><p><strong>Results: </strong>The three groups showed a gradient with descending values (group 3 > group 2 > group 1) for SBP, LV ejection fraction, global longitudinal strain, arterial elastance, and ventricular-arterial coupling, with the opposite gradient (group 1 > group 2 > group 3) for LVEDV, LVESV, SV, and left atrial volume index values (P < .01 for all). After a median follow-up period of 16 months, 205 MACEs occurred in 138 patients. The cumulative MACE rate was lowest in group 2 (14.7% person-years) and higher in groups 1 (16.1% person-years) and 3 (22.9% person-years; log-rank P = .036).</p><p><strong>Conclusions: </strong>Patients with HFpEF present with different LV contractile phenotypes, easily identified with resting LV force and volumetric transthoracic echocardiography. The dominant hemodynamic feature of hypocontractile phenotype is a preload recruitment with larger LVEDV and normal SV, while the hypercontractile phenotype is characterized by a small left ventricle with reduced SV. The hypercontractile and hypocontractile phenotypes are associated with a higher risk for subsequent events.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishing dosing parameters for the use of maternal hyperoxygenation to affect fetal cardiovascular physiology.","authors":"Michelle Kaplinski, Aaron A Phillips, Megha D Tandel, Yingjie Weng, Kelly Thorson, Katie Jo Stauffer, Sandra Moon, Adam Frymoyer, Virginia D Winn, Theresa A Tacy, Shiraz A Maskatia","doi":"10.1016/j.echo.2025.01.004","DOIUrl":"https://doi.org/10.1016/j.echo.2025.01.004","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood Pressure and Echocardiographic Interpretation: Guideline Revision Needed.","authors":"Christopher Lee, Theodore P Abraham, Nelson B Schiller","doi":"10.1016/j.echo.2025.01.003","DOIUrl":"10.1016/j.echo.2025.01.003","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reevaluating Normal-Flow Low-Gradient Severe Aortic Stenosis: Clinical Phenotypes and Outcomes in Severe Aortic Stenosis Among Transcatheter Aortic Valve Replacement Patients.","authors":"Amro Badr, Mustafa Suppah, Kamal Awad, Juan Farina, Bobbi Jo Heon, Rachel Wraith, Bishoy Abraham, Sara Kaldas, Vuyisile Nkomo, Reza Arsanjani, Chieh-Ju Chao, David Holmes, Said Alsidawi","doi":"10.1016/j.echo.2024.12.010","DOIUrl":"10.1016/j.echo.2024.12.010","url":null,"abstract":"<p><strong>Background: </strong>Aortic stenosis (AS) is a complex condition with various hemodynamic subtypes, each with distinct clinical profiles and outcomes. The aim of this study was to assess the characteristics and outcomes of different AS phenotypes on the basis of flow and gradient patterns.</p><p><strong>Methods: </strong>In this retrospective cohort study, 930 patients who underwent transcatheter aortic valve replacement for severe symptomatic AS at Mayo Clinic sites from 2012-2017 were included. Patients were classified into three groups: high gradient (HG), low-flow low-gradient (LFLG), and normal-flow low-gradient (NFLG). Baseline clinical, echocardiographic, and computed tomographic characteristics, including aortic valve area, aortic valve calcium score, left ventricular ejection fraction, and the prevalence of tricuspid regurgitation, and atrial fibrillation were analyzed. One- and 5-year all-cause mortality outcomes were compared using Kaplan-Meier analysis and Cox proportional-hazards models.</p><p><strong>Results: </strong>The final cohort included 273 patients in the NFLG group (29.4%), 563 in the HG group (60.5%), and 94 in the LFLG group (10.1%). After reevaluation and careful review of the echocardiograms, 41 patients with NFLG AS were reclassified into the LFLG group. Patients with LFLG AS had the highest prevalence of atrial fibrillation or flutter (60%) and tricuspid regurgitation (17%). Aortic valve calcium score was significantly lower in the NFLG group compared with the HG and LFLG groups. One-year mortality was highest in the LFLG group (17.4%), followed by the HG (13.9%) and NFLG (10.9%) groups, but the difference was not statistically significant (P = .20). The 5-year mortality rate was higher in the LFLG group (55.6%) compared with the NFLG (47.2%) and HG (47.9%) groups but did not reach statistical significance (P = .20).</p><p><strong>Conclusions: </strong>LFLG AS was associated with more comorbidities and higher mortality compared with HG and NFLG AS, though differences in mortality were not statistically significant. The NFLG group, after close review and reclassification, showed the least significant AS. Randomized trials are needed to clarify the prognosis and management of NFLG AS.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute maternal hyperoxygenation to predict hypoxia and need for emergency intervention in fetuses with transposition of the great arteries: a pilot study.","authors":"Trisha Vigneswaran, Chris Oakley, Hannah R Bellsham-Revell, Matthew Jones, Vita Zidere, Reza Razavi, John Simpson","doi":"10.1016/j.echo.2024.12.011","DOIUrl":"https://doi.org/10.1016/j.echo.2024.12.011","url":null,"abstract":"<p><strong>Background: </strong>Newborns with transposition of the great arteries (TGA) are at risk of severe hypoxia from inadequate atrial mixing, closure of the arterial duct and/or pulmonary hypertension (PPHN). Acute maternal hyperoxygenation (AMH) might assist in identifying at-risk fetuses. We report pulmonary vasoreactivity to AMH in TGA fetuses and its relationship to early postnatal hypoxia and requirement for emergency balloon atrial septostomy (e-BAS).</p><p><strong>Methods: </strong>Standard fetal echocardiographic (FE) assessment of the foramen ovale (FO): total septal length and morphology of flap valve of FO were used to predict need for e-BAS. Following prospective recruitment, additional assessments were performed in fetuses with TGA at baseline and repeated after 10minutes of 10L/min of 100% oxygen delivered via non-rebreather mask to the pregnant mother. Analysis included measurement of atrial septal excursion, branch pulmonary artery pulsatility index (PA-PI), middle cerebral artery (MCA) PI and cardiac output. Delivery and newborn status were reviewed. Hypoxia was defined as preductal oxygen saturations <75% and e-BAS when undertaken within two hours of birth. Area under receiver operating characteristics curves (AUROC) were calculated.</p><p><strong>Results: </strong>30 cases underwent FE at 34.6weeks' gestation (IQR: 34.6-35.6). All 7 predicted to require e-BAS based on standard FE were correctly identified prenatally. 3/30 were hypoxic without FO restriction and treated with nitric oxide (PPHN). Change in PA-PI < 15% was associated with PPHN (p=0.001), but not with e-BAS. The MCA-PI response to AMH varied according to newborn condition, a mean reduction occurred in the non-hypoxic newborns (-7.8 ± 18.3, p=0.05). Increase in MCA-PI Z score AUROC 0.837 (95% CI: 0.663-1.00, p=0.01); reduction in right ventricular cardiac output 0.811 (95% CI: 0.623-0.998, p=0.04), reduction in combined cardiac output (0.851 (95% CI: 0.699-1.0, p=0.01)) were moderately associated with e-BAS. Changes in atrial septal excursion and FO flow direction with AMH did not correlate with newborn condition.</p><p><strong>Conclusions: </strong>PA-PI change < 15% to AMH was associated with postnatal hypoxia due to PPHN. Increase in right and combined cardiac output and reduced MCA resistance with AMH are seen in those who do not require e-BAS.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dapagliflozin and Cardiac Reverse Remodeling: New Insights in the Mechanistic Puzzle of SGLT2 Inhibitors.","authors":"Safia Chatur, Timothy W Churchill","doi":"10.1016/j.echo.2025.01.002","DOIUrl":"10.1016/j.echo.2025.01.002","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuing Education and Meeting Calendar","authors":"","doi":"10.1016/j.echo.2024.11.003","DOIUrl":"10.1016/j.echo.2024.11.003","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Page A23"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143165982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Echocardiography Feature-Tracking Algorithm for Stabilized Frame-to-Frame Extraction of Aortic Root Diameters in the Parasternal Long Axis","authors":"Frederick W. Damen MD, PhD,&nbsp;Elnaz Ghajar-Rahimi BS,&nbsp;Dongbing Lai PhD,&nbsp;Craig J. Goergen PhD,&nbsp;Benjamin J. Landis MD","doi":"10.1016/j.echo.2024.09.005","DOIUrl":"10.1016/j.echo.2024.09.005","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages 44-47"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitral Leaflet Separation Revisited: A Surrogate of Mitral Valve Area in Young People With Rheumatic Mitral Regurgitation Living in Remote Areas","authors":"Jacqueline M. Williamson BSc,&nbsp;Bo Remenyi MBBS, PhD,&nbsp;Ari E. Horton MBBS,&nbsp;Peter Morris MBBS, PhD,&nbsp;Gillian A. Whalley PhD","doi":"10.1016/j.echo.2024.10.005","DOIUrl":"10.1016/j.echo.2024.10.005","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages 49-50"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}