Chadi Ayoub, Isabel G Scalia, S Allen Luis, Juan A Crestanello, William J Mauermann, Thorvardur R Halfdanarson, Heidi Connolly, Patricia A Pellikka
{"title":"Echocardiographic Evaluation of Carcinoid Heart Disease.","authors":"Chadi Ayoub, Isabel G Scalia, S Allen Luis, Juan A Crestanello, William J Mauermann, Thorvardur R Halfdanarson, Heidi Connolly, Patricia A Pellikka","doi":"10.1016/j.echo.2025.05.013","DOIUrl":null,"url":null,"abstract":"<p><p>Carcinoid heart disease (CaHD) is a complication that occurs in patients with metastatic neuroendocrine tumors (usually to the liver) and carcinoid syndrome. Hormonal release causes endocardial thickening, typically affecting right-sided cardiac valves. Symptomatic patients with CaHD have a poor prognosis, and management of valvular heart disease is complicated by metastasis and other associated conditions and carries a higher risk than management of other acquired valve disease. Clinical and biomarker assessment are used for screening and echocardiography is the diagnostic imaging backbone used for identification of CaHD, as well as grading of severity of valvular lesions and associated chamber dysfunction. Echocardiography is critical in the evaluation for surgical intervention, as well as in guiding surgery and postoperative surveillance. This article reviews in detail applications of echocardiography in patients with CaHD.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4000,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the American Society of Echocardiography","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.echo.2025.05.013","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Carcinoid heart disease (CaHD) is a complication that occurs in patients with metastatic neuroendocrine tumors (usually to the liver) and carcinoid syndrome. Hormonal release causes endocardial thickening, typically affecting right-sided cardiac valves. Symptomatic patients with CaHD have a poor prognosis, and management of valvular heart disease is complicated by metastasis and other associated conditions and carries a higher risk than management of other acquired valve disease. Clinical and biomarker assessment are used for screening and echocardiography is the diagnostic imaging backbone used for identification of CaHD, as well as grading of severity of valvular lesions and associated chamber dysfunction. Echocardiography is critical in the evaluation for surgical intervention, as well as in guiding surgery and postoperative surveillance. This article reviews in detail applications of echocardiography in patients with CaHD.
期刊介绍：
The Journal of the American Society of Echocardiography(JASE) brings physicians and sonographers peer-reviewed original investigations and state-of-the-art review articles that cover conventional clinical applications of cardiovascular ultrasound, as well as newer techniques with emerging clinical applications. These include three-dimensional echocardiography, strain and strain rate methods for evaluating cardiac mechanics and interventional applications.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
