Journal of the American Society of Echocardiography最新文献

{"title":"Artificial Intelligence in Echocardiography-Revolution or Replacement?","authors":"Nihil Abraham, Thriveni Sanagala, Mariya Stoilova, Ilya Karagodin","doi":"10.1016/j.echo.2025.04.012","DOIUrl":"10.1016/j.echo.2025.04.012","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Normal Values of Echocardiographic Left Atrioventricular Coupling Index and Left Atrial Stiffness Index Reflecting Left Ventricular Diastolic Function: A Multicenter Study.","authors":"Tian-Xin Dong, Shi-Wen Li, Xiao-Fang Pan, Chun-Feng Wang, Ying Liu, Jun Wu, Xiang-Ping Guan, Su-Li Zhang, Peng-Fei Zuo, Yi-Lin Liu, Li-Yan Wang, Lei Cui, Yan Liu, Yu-Qiong Lai, Ming-Yan Ding, Gui-Lin Lu, Jing Tan, Xin-Jian Yang, Yi-Hong Li, Yong-Huai Wang, Xin-Tong Zhang, Wei-Dong Ren, Chun-Yan Ma","doi":"10.1016/j.echo.2025.04.011","DOIUrl":"10.1016/j.echo.2025.04.011","url":null,"abstract":"<p><strong>Background: </strong>The left atrioventricular coupling index (LACI) and left atrial stiffness index (LASI) have recently demonstrated significant correlations with left ventricular (LV) diastolic function. However, the absence of reference values limits their widespread use. This study aimed to establish normal reference ranges for LACI and LASI.</p><p><strong>Methods: </strong>A total of 1,648 healthy participants from 55 centers were enrolled. The LACI was defined as the ratio of left atrial (LA) minimum volume to LV end-diastolic volume. The LASI was calculated as the ratio of the average E/e' ratio to LA reservoir strain.</p><p><strong>Results: </strong>Both LACI and LASI increased with age in both sexes. The LACI was higher in women than in men (P < .001), whereas no significant sex difference was observed for LASI (P = .868). Age, sex, LV global longitudinal strain (GLS), and LA reservoir strain independently predicted LACI. Age, body mass index, LV GLS, and LA volume index were independently associated with LASI. Elevated LACI and LASI were observed in participants with high-normal blood pressure, overweight status, and indeterminate LV diastolic function.</p><p><strong>Conclusions: </strong>Sex- and age-stratified reference values for LACI and LASI were established. Left ventricular GLS, LA reservoir strain, and LA volume index should be considered when interpreting these parameters. Hypertension, obesity, and LV diastolic dysfunction may significantly affect LACI and LASI, suggesting their potential utility in identifying early cardiac dysfunction.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spotlight on the Right Ventricle: Why We Need to Do Better.","authors":"Mary Acosta, Karima Addetia","doi":"10.1016/j.echo.2025.04.010","DOIUrl":"10.1016/j.echo.2025.04.010","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitation of Primary Mitral Regurgitation: A Fresh Take on an Old Method.","authors":"Gerard P Aurigemma, Matthew W Parker","doi":"10.1016/j.echo.2025.04.009","DOIUrl":"10.1016/j.echo.2025.04.009","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Renal Function on Myocardial Remodeling and Outcomes in Patients With Moderate Aortic Stenosis.","authors":"Hyun-Jung Lee, Kyu Kim, Seo-Yeon Gwak, Iksung Cho, Geu-Ru Hong, Jong-Won Ha, Chi Young Shim","doi":"10.1016/j.echo.2025.04.008","DOIUrl":"10.1016/j.echo.2025.04.008","url":null,"abstract":"<p><strong>Background: </strong>Patients with moderate aortic stenosis (AS) and cardiac damage have poor prognosis, and whether early aortic valve replacement benefits these patients is under investigation. However, besides valvular hemodynamics, comorbidities such as chronic kidney disease (CKD) can contribute to myocardial damage and affect prognosis. The aim of this study was to investigate the impact of renal function on myocardial remodeling and outcomes in patients with moderate AS.</p><p><strong>Methods: </strong>The study cohort included 865 consecutive patients diagnosed with moderate AS (aortic valve area > 1.0 and ≤1.5 cm², mean gradient > 20 mmHg) between 2008 and 2020. Patients were categorized into five stages of CKD according to estimated glomerular filtration rate. Echocardiographic measures of myocardial remodeling and the composite outcome of all-cause mortality and heart failure hospitalization were assessed.</p><p><strong>Results: </strong>Higher CKD stage was associated with greater valvuloarterial impedance, as well as greater left ventricular (LV) hypertrophy, worse LV diastolic function, and lower LV and left atrial strain, despite similar AS severity. These associations were independent of age, sex, comorbidities, and LV pressure overload. During a median follow-up period of 4.0 years, 310 composite outcome events (39.3%) occurred, including 258 deaths (32.7%). Severe CKD (stage 4 or 5) and myocardial dysfunction were independent predictors of the composite outcome, after adjustment for key clinical variables including aortic valve replacement. Mediation analysis showed that myocardial dysfunction partially mediated the impact of renal function on outcome.</p><p><strong>Conclusions: </strong>In patients with moderate AS, renal dysfunction was independently associated with adverse myocardial remodeling and dysfunction, irrespective of valvular hemodynamics. The role of earlier intervention in patients with moderate AS whose cardiac damage is driven by comorbidities, rather than AS itself, warrants further investigation.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduced Right Ventricular Size and Function in Adolescents and Adults Born Preterm.","authors":"Zachary W Blair, Alvin Chandra, Gregory P Barton, Nataly Sanchez Solano, Jarett D Berry, Kara N Goss","doi":"10.1016/j.echo.2025.04.007","DOIUrl":"10.1016/j.echo.2025.04.007","url":null,"abstract":"<p><strong>Background: </strong>Adults born premature have smaller cardiac chamber sizes, and some develop right ventricular (RV) dysfunction. Risk factors for RV dysfunction into adulthood remain unclear. The aim of this study was to investigate right-sided cardiac structure and function among adolescents and adults born preterm.</p><p><strong>Methods: </strong>Participants born moderately to extremely premature (≤32 weeks) or at very low birth weight (<1500 g) aged 12 to 40 years were recruited from the Parkland Health Neonatal Intensive Care Unit Registry. Healthy term-born similarly aged participants were recruited from Dallas County. Study visits included anthropometric measurements, a cardiopulmonary examination, and echocardiography. Multivariable linear regression models were used to determine the main effect of prematurity (yes or no) and gestational age on right atrial and RV structure and function after adjusting for age, sex, body surface area, and birth weight Z scores.</p><p><strong>Results: </strong>Preterm participants (n = 107) had a mean gestational age of 29.3 ± 2.7 weeks and a mean birth weight of 1,320 ± 398 g. Compared with term participants (n = 48), echocardiography demonstrated smaller right atrial volume and RV area. Tricuspid annular plane systolic excursion, tissue Doppler imaging systolic tricuspid annular peak velocity (RV s'), and early diastolic velocity (RV e') were lower in preterm participants, with a significant dose response with gestational age and in the absence of overt pulmonary hypertension.</p><p><strong>Conclusions: </strong>Right-sided chamber sizes were smaller, with reduced tricuspid annular plane systolic excursion, RV s', and RV e' in adolescents and adults born premature, with a clear association with gestational age. Reduced RV function in the absence of overt pulmonary hypertension suggests preterm birth imparts an independent insult on the developing RV with lifetime implications.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical Adaptation of the Right Ventricle to Secondary Tricuspid Regurgitation and Its Association With Patients' Outcomes.","authors":"Edith Liliana Posada-Martinez, Lissa Sugeng","doi":"10.1016/j.echo.2025.04.006","DOIUrl":"10.1016/j.echo.2025.04.006","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiographic Estimate of Pulmonary Capillary Wedge Pressure Improves Outcome Prediction in Heart Failure Patients With Reduced and Mildly Reduced Ejection Fraction.","authors":"Lorenzo Bazan, Francesco Gentile, Paolo Sciarrone, Francesco Buoncristiani, Giorgia Panichella, Simone Gasparini, Claudia Taddei, Elisa Poggianti, Iacopo Fabiani, Christina Petersen, Giuseppe Emanuele Lio, Patrizio Lancellotti, Claudio Passino, Michele Emdin, Vladislav Chubuchny, Alberto Giannoni","doi":"10.1016/j.echo.2025.04.005","DOIUrl":"10.1016/j.echo.2025.04.005","url":null,"abstract":"<p><strong>Background: </strong>An echocardiographic algorithm to estimate pulmonary capillary wedge pressure (ePCWP) and pulmonary vascular resistance (ePVR) has been recently validated versus right heart catheterization.</p><p><strong>Objective: </strong>To assess the prognostic significance of these measures in heart failure (HF) patients with reduced and mildly reduced ejection fraction.</p><p><strong>Methods: </strong>Consecutive outpatients with HF and left ventricular ejection fraction (LVEF) <50% undergoing echocardiography were selected and followed up for the composite end point of all-cause death or HF hospitalization.</p><p><strong>Results: </strong>Out of 2,214 patients (71 ± 12 years, 76% males, LVEF 35% ± 9%), ePCWP (16 ± 6 mm Hg) was elevated (>15 mm Hg) in 52% of cases and ePVR (1.7 ± 0.7 Wood units) was elevated (>2 Wood units) in 25% of cases. Patients with increased ePCWP were older and had a higher New York Heart Association class, more pronounced cardiac remodeling, systolic/diastolic dysfunction, and neurohormonal activation, particularly when ePVR was also elevated (P < .001). Over a median follow-up of 33 (17-48) months, both measures stratified patients for the risk of the primary end point (log-rank 151 for ePCWP and 60 for ePVR; P < .001). At adjusted regression analysis, ePCWP (hazard ratio for 1 mm Hg increase 1.03 [95% CI, 1.01-1.04]; P < .001) but not ePVR (P = .07) predicted the primary end point, even in patients with atrial fibrillation (P = .019), outperforming current diastolic dysfunction grading (P < .001) and both E/e' and left atrial volume index (P < .001). The addition of ePCWP to a multivariable prognostic model improved the accuracy of risk prediction (P < .001).</p><p><strong>Conclusion: </strong>The echocardiographic estimates of PCWP retained clinical and prognostic significance in a large contemporary cohort of patients with chronic HF and LVEF <50%.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indexing Tricuspid Annular Systolic Plane Excursion to Right Ventricular Length as a Surrogate of Right Ventricular Free Wall Strain.","authors":"Philippe Unger, Michaël Rietz, Xavier Galloo","doi":"10.1016/j.echo.2025.04.003","DOIUrl":"https://doi.org/10.1016/j.echo.2025.04.003","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep Learning-Based Detection and Severity Assessment of Bicuspid Aortic Valve Stenosis.","authors":"Jiesuck Park, Jiyeon Kim, Jaeik Jeon, Yeonyee E Yoon, Yeonggul Jang, Hyunseok Jeong, Seung-Ah Lee, Hong-Mi Choi, In-Chang Hwang, Goo-Yeong Cho, Hyuk-Jae Chang","doi":"10.1016/j.echo.2025.04.002","DOIUrl":"https://doi.org/10.1016/j.echo.2025.04.002","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}