Journal of the American Society of Echocardiography最新文献

{"title":"Distance Between the Anterior Papillary Muscle and Interventricular Septum Evaluated by Echocardiography to Diagnose Midventricular Obstruction in Hypertrophic Cardiomyopathy.","authors":"Minghu Xiao, Jingjin Wang, Changrong Nie, Changsheng Zhu, Xin Sun, Yanhai Meng, Zhenhui Zhu, Hao Wang, Shuiyun Wang","doi":"10.1016/j.echo.2025.04.018","DOIUrl":"10.1016/j.echo.2025.04.018","url":null,"abstract":"<p><strong>Background: </strong>Left ventricular midventricular obstruction (MVO) is thought to be dynamic with hypertrophic cardiomyopathy (HCM). Therefore, the distance between the anterior papillary muscle (APM) and the interventricular septum (IVS) was used to assess MVO on rest echocardiography.</p><p><strong>Methods: </strong>MVO was defined as a midventricular gradient of ≥30 mm Hg at rest or after being provoked. APM-IVS distance was analyzed in the apical three-chamber view at end-diastole.</p><p><strong>Results: </strong>A total of 2,125 patients with HCM were enrolled in this study. Among these, data from 1,453 patients with measurable APM-IVS distances were analyzed. Of the 1,453 patients, 596 had MVO, while 857 did not exhibit MVO. Multivariate logistic regression analyses showed that APM-IVS distance was an independent indicator of MVO (adjusted odds ratio, 0.487; 95% CI, 0.448-0.529). APM-IVS distance demonstrated the highest diagnostic accuracy in identifying MVO, exhibiting an area under the receiver operating characteristic curve of 0.949 (95% CI, 0.937-0.960). The presence of a smaller APM-IVS distance was correlated with increased incidence of left ventricular apical aneurysm and MVO, elevated levels of N-terminal pro-brain natriuretic peptide, and higher New York Heart Association functional class. Among patients with MVO, 198 underwent surgical myectomy and were followed up after a median time of 12 months. APM-IVS distance increased from 7.6 ± 2.2 to 18.9 ± 4.9 mm, and the peak midventricular gradient decreased from 50 mm Hg (36-57 mm Hg) to 3 mm Hg (3-7 mm Hg) at follow-up.</p><p><strong>Conclusions: </strong>A small APM-IVS distance was associated with MVO, which was alleviated after myectomy following an increase in APM-IVS distance.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Body Surface Area a Good Anthropometric Scaling Variable for Detecting Differences in Right Atrial and Right Ventricular Structural Parameters in Adults Born Term Versus Preterm?","authors":"Curt G DeGroff","doi":"10.1016/j.echo.2025.04.015","DOIUrl":"10.1016/j.echo.2025.04.015","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flow State in Aortic Stenosis: \"Whatever the Parameters, as Long as We Identify the Risk\".","authors":"Marie-Annick Clavel, Lionel Tastet","doi":"10.1016/j.echo.2025.04.014","DOIUrl":"10.1016/j.echo.2025.04.014","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echo-Diastology Prediction of Heart Failure Outcomes: Are We Closer to Finding the Rosetta Stone?","authors":"Garred S Greenberg, Mario J Garcia","doi":"10.1016/j.echo.2025.04.013","DOIUrl":"10.1016/j.echo.2025.04.013","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Elastography With External Vibration for Quantification of Diastolic Myocardial Stiffness","authors":"Tom Meyer MSc ,&nbsp;Brunhilde Wellge ,&nbsp;Gina Barzen MD ,&nbsp;Stefan Klemmer Chandia MSc ,&nbsp;Fabian Knebel MD ,&nbsp;Katrin Hahn MD ,&nbsp;Thomas Elgeti MD ,&nbsp;Thomas Fischer MD ,&nbsp;Jürgen Braun PhD ,&nbsp;Heiko Tzschätzsch PhD ,&nbsp;Ingolf Sack PhD","doi":"10.1016/j.echo.2024.11.009","DOIUrl":"10.1016/j.echo.2024.11.009","url":null,"abstract":"<div><h3>Objectives</h3><div>Heart failure is an increasing global health problem. Approximately 50% of patients with heart failure have heart failure with preserved ejection fraction (HFpEF) and concomitant diastolic dysfunction (DD), in part caused by increased myocardial stiffness not detectable by standard echocardiography. While elastography can map tissue stiffness, cardiac applications are currently limited, especially in patients with a higher body mass index. Therefore, we developed cardiac time-harmonic elastography (THE) to detect abnormal diastolic myocardial stiffness associated with DD.</div></div><div><h3>Material and Methods</h3><div>Cardiac THE was developed using standard medical ultrasound and continuous external vibration for regionally resolved mapping of diastolic shear wave speed as a proxy for myocardial stiffness. The method was prospectively applied to 54 healthy controls (26 women), 10 patients with moderate left ventricular hypertrophy (mLVH; 5 women), and 45 patients with wild-type transthyretin amyloidosis (wTTR; 4 women), 20 of whom were treated with tafamidis. Ten healthy participants were reinvestigated after 2 to 6 months to analyze test-retest reproducibility by intraclass correlation coefficients.</div></div><div><h3>Results</h3><div>Myocardial shear wave speed was measured with good reproducibility (intraclass correlation coefficient = 0.82) and showed higher values in wTTR (3.0 ± 0.7 m/sec) than in mLVH (2.1 ± 0.6 m/sec) and healthy controls (1.8 ± 0.3 m/sec, all <em>P</em> &lt; .05). Area under the curve values were 0.991 and 0.737 for discriminating wTTR and mLVH from healthy controls, respectively. Shear wave speed was reduced in patients after tafamidis treatment (2.6 ± 0.6 m/sec, <em>P</em> = .04), suggesting the potential value of THE for therapy monitoring. Shear wave speed was quantified in the septum, posterior wall, and an automatically masked region (here stated for the septal region).</div></div><div><h3>Conclusions</h3><div>Cardiac THE detects abnormal myocardial stiffness in patients with DD with high penetration depth, independent of body mass index and region selection. Based on standard ultrasound components, cardiac THE is cost-effective and has the potential to become a point-of-care method for stiffness-sensitive echocardiography.</div></div>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 5","pages":"Pages 431-442"},"PeriodicalIF":5.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dapagliflozin and Cardiac Reverse Remodeling: New Insights in the Mechanistic Puzzle of SGLT2 Inhibitors","authors":"Safia Chatur MD ,&nbsp;Timothy W. Churchill MD","doi":"10.1016/j.echo.2025.01.002","DOIUrl":"10.1016/j.echo.2025.01.002","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 5","pages":"Pages 404-408"},"PeriodicalIF":5.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep Duration and Subclinical Left Ventricular Dysfunction in Older Adults","authors":"Yuriko Yoshida MD,&nbsp;Zhezhen Jin PhD,&nbsp;Cesare Russo MD,&nbsp;Shunichi Homma MD,&nbsp;Carlo Mannina MD,&nbsp;Koki Nakanishi MD,&nbsp;Tatjana Rundek MD, PhD,&nbsp;Mitchell S.V. Elkind MD, MS,&nbsp;Marco R. Di Tullio MD","doi":"10.1016/j.echo.2024.11.002","DOIUrl":"10.1016/j.echo.2024.11.002","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 5","pages":"Pages 443-445"},"PeriodicalIF":5.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Doppler Characterization of Left Anterior Descending Coronary Artery Diastolic Flow Profiles in Hypertrophic Cardiomyopathy","authors":"Matthew Peters MD,&nbsp;Patrycja Galazka MD,&nbsp;McKenzie Schweitzer RDCS, FASE,&nbsp;Zaid Abood MD,&nbsp;M. Fuad Jan MBBS (Hons), MD,&nbsp;Renuka Jain MD,&nbsp;A. Jamil Tajik MD","doi":"10.1016/j.echo.2025.01.012","DOIUrl":"10.1016/j.echo.2025.01.012","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 5","pages":"Pages 445-447"},"PeriodicalIF":5.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to Unveiling the Left Atrioventricular Coupling Index: A Promising Marker for Diastolic Dysfunction and Prognosis","authors":"Federico Fortuni MD,&nbsp;Paolo Biagioli MD,&nbsp;Erberto Carluccio MD","doi":"10.1016/j.echo.2025.01.011","DOIUrl":"10.1016/j.echo.2025.01.011","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 5","pages":"Pages 448-449"},"PeriodicalIF":5.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lessons from Diastolic Function Assessment After Myocardial Infarction","authors":"Jae K. Oh MD,&nbsp;Eunjung Lee PhD","doi":"10.1016/j.echo.2025.02.016","DOIUrl":"10.1016/j.echo.2025.02.016","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 5","pages":"Pages 392-394"},"PeriodicalIF":5.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}