Journal of Thoracic Imaging最新文献

{"title":"Community-acquired Pneumonia: Diagnostic Challenges in Non-immunocompromised Patients.","authors":"Tomás Franquet, Jose M Brenes, Ana Giménez, Pere Domingo","doi":"10.1097/RTI.0000000000000905","DOIUrl":"https://doi.org/10.1097/RTI.0000000000000905","url":null,"abstract":"<p><p>Community-acquired pneumonia (CAP) remains a leading cause of morbidity and mortality worldwide, affecting individuals outside health care settings. Streptococcus pneumoniae is the predominant pathogen, although regional and socioeconomic factors significantly influence epidemiology, resistance patterns, and outcomes. Diagnosis relies on clinical evaluation supported by imaging, microbiology, and biomarkers, yet presentations are highly variable across age groups and comorbidities. Chest radiography remains the cornerstone for initial assessment, while high-resolution CT (HRCT) offers superior sensitivity for early detection and complications. Typical bacterial pathogens (eg, S. pneumoniae, Haemophilus influenzae, Klebsiella pneumoniae) produce lobar or bronchopneumonic consolidations, whereas atypical organisms (Mycoplasma, Chlamydia, Legionella) and viruses often yield diffuse ground-glass or interstitial patterns. Fungal and mycobacterial infections must also be considered, particularly in endemic regions. Radiologic-pathologic correlation is essential to differentiate CAP etiologies, guide management, and identify complications such as cavitation, empyema, or necrosis. Understanding these imaging patterns within global and clinical contexts is critical for improving diagnostic accuracy and optimizing patient outcomes.</p>","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148867508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Value of Calcium Score Derived From Virtual Noncontrast, Non-ECG-gated Dual-energy CT as an Indicator of Severe Aortic Stenosis.","authors":"Jakub Byczkowski, Gregorio Chierchia, Giuseppe Muscogiuri, Edoardo Sciatti, Francesco Severi, Katarzyna Sienkiewicz, Pietro Andrea Bonaffini, Jadwiga Fijałkowska, Edyta Szurowska, Răzvan-Andrei Licu, Piotr Tarkowski, Marianna Mirchuk, Longjiang Zhang, Michele Senni, Sandro Sironi","doi":"10.1097/RTI.0000000000000904","DOIUrl":"https://doi.org/10.1097/RTI.0000000000000904","url":null,"abstract":"<p><strong>Study type: </strong>Retrospective monocentric study.</p><p><strong>Purpose: </strong>To estimate the probability of severe aortic stenosis(SAS) by calculating the aortic valve calcium score (AVCS) using virtual noncontrast (VNC) reconstructions derived from non-ECG-gated dual-energy computed tomography (DECT) scans.</p><p><strong>Materials and methods: </strong>This study retrospectively included 59 patients who underwent DECT scans for noncardiac indications and presented with visible aortic valve calcifications. AVCS was calculated on VNC images using semiautomatic software. All patients had an echocardiogram performed within 12 months before or after the DECT scan. We then analyzed the correlation between AVCS values and the degree of aortic stenosis.</p><p><strong>Results: </strong>Both male and female patients with SAS had a significantly higher mean AVCS (919.2 AU, SD=1262.4) compared with those with nonsevere aortic stenosis (NSAS) (127.9 AU, SD=278.6). AVCS demonstrated good diagnostic performance in distinguishing between severe and nonsevere AS in both female and male (AUC=0.91 and 0.95, respectively). Estimated thresholds values showed high sensitivity in both genders, with good specificity in men, and moderate in women. When analyzed irrespective of gender, AVCS demonstrated good ability to distinguish severe AS from mild and no stenosis (AUC=0.926), and moderate ability to distinguish moderate AS from mild and no stenosis (AUC=0.781). However, it lacked statistical significance in discriminating severe and moderate AS (AUC=0.714, P=0.1325).</p><p><strong>Conclusions: </strong>Aortic Valve Calcium Score obtained on VNC images from DECT examinations is a promising method for noninvasively differentiation between severe and nonsevere aortic stenosis, which could be potentially useful in patients who have undergone examinations for noncardiac indications.</p>","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148800825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Long-term Temporal Evolution of Chest CT Findings in Granulomatous-lymphocytic Interstitial Lung Disease.","authors":"Rosita M Shah, Drew A Torigian","doi":"10.1097/RTI.0000000000000908","DOIUrl":"https://doi.org/10.1097/RTI.0000000000000908","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study is to document the long-term natural history of granulomatous-lymphocytic interstitial lung disease (GLILD), including evolving chest CT features and prevalence of pulmonary fibrosis at follow-up of patients with longstanding disease.</p><p><strong>Materials and methods: </strong>This retrospective longitudinal study compares the CT features of GLILD in a cohort of patients with at least 2 chest CTs performed >24 months apart. A radiologic database identified 22 patients (median age 45.8 years, 13 females and 9 males) with common variable immunodeficiency (CVID) and a clinico-radio-pathologic or clinico-radiologic diagnosis of GLILD. Two chest radiologists jointly reviewed the chronologically first (CT1) and last (CT2) available chest CT examinations for each subject, scoring the severity of different pulmonary nodule types, features of pulmonary fibrosis, ground-glass opacity, and consolidation. Total severity score (TSS) for each category of CT features at CT1 and CT2 was compared using the Wilcoxon signed-rank test.</p><p><strong>Results: </strong>On follow-up averaging 135 months (range 33-235 months) from CT1, CT2 studies demonstrated significantly decreased nodule TSS (P=0.01), significantly increased fibrosis TSS (P=0.0001), and relatively stable ground-glass opacity TSS (P=0.81) and consolidation TSS (P=0.72). Nodule TSS decreased in 73% of patients, in which peribronchial nodules < or ≥10 mm and perilymphatic nodules < or ≥5 mm improved. Fibrosis TSS increased in 82% of patients who developed new or worsening traction bronchiectasis, architectural distortion, and honeycombing.</p><p><strong>Conclusion: </strong>CT features of GLILD evolve over time, with new or worsening fibrosis recognized in 82% of patients at long-term follow-up.</p>","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148800684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Defining an Upper Hounsfield Unit Threshold for Acute Pulmonary Embolism in Computed Tomography Pulmonary Angiography.","authors":"Arun C Nachiappan, Andrew C Hu, Priscilla Stecher, Yvonne Su, Achala Donuru, Julia C M Jacob, Jaydev K Dave, Scott A Simpson, Steven C Pugliese, Nyasha G Maforo, Faisal Jamal","doi":"10.1097/RTI.0000000000000896","DOIUrl":"10.1097/RTI.0000000000000896","url":null,"abstract":"<p><strong>Purpose: </strong>To measure the computed tomography (CT) attenuation of acute pulmonary embolism (PE) and establish an upper Hounsfield unit (HU) threshold above which it is unlikely to occur.</p><p><strong>Materials and methods: </strong>This retrospective study analyzed CT pulmonary angiography (CTPA) exams in patients with acute PE (2018-2023) who had a prior negative CTPA in the preceding 2 weeks. Clot and artifact attenuation were measured on the positive and prior negative CTPA respectively. Analysis of variance with post hoc tests and linear regression analysis were performed to determine the effects of technical and other parameters on clot and artifact attenuation.</p><p><strong>Results: </strong>A total of 60 patients were included, each with 1 record or a pair of CTPA exams, yielding 105 clots and 41 artifacts. Mean attenuation for acute PE was 50±40 HU, and for artifact was 110±146 HU. A threshold of 125 HU achieved 97% (102/105) sensitivity for acute PE below it and the same specificity for artifact above it. Specificity for acute PE below this threshold was 37% (15/41). Subsegmental clots had a lower attenuation than all other clots as a group. Kilovoltage peak (kVp) and proximal vessel attenuation were poor predictors of clot attenuation.</p><p><strong>Conclusions: </strong>Most acute PE demonstrated a CT attenuation ≤125 HU on standard CTPA, an upper threshold higher than previously reported, while artifacts demonstrated both lower and higher attenuation. An attenuation >125 HU on standard CTPA, favoring artifact rather than acute PE, may be a useful adjunct to morphologic differentiation between these entities.</p>","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148765775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe Fever With Thrombocytopenia Syndrome: An Autopsy-Proven Case With Radiologic-Pathologic Correlation.","authors":"Haruka Sato, Fumito Okada, Ryuichi Takenaka, Ryuzo Abe, Haruto Nishida, Yoshiki Asayama","doi":"10.1097/RTI.0000000000000898","DOIUrl":"https://doi.org/10.1097/RTI.0000000000000898","url":null,"abstract":"<p><p>Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne viral infection that can rapidly progress to multiple organ failure with a high mortality rate. Pulmonary involvement has been reported, but the radiologic-pathologic correlation remains poorly understood. We report an autopsy-proven fatal case of SFTS in a 79-year-old man with pre-existing collagen vascular disease-associated interstitial lung disease. Serial chest computed tomography (CT) initially demonstrated subtle peripheral ground-glass opacities that progressively expanded over time. On the final CT examination obtained shortly before death, extensive bilateral consolidation with high attenuation on mediastinal window images was observed, suggestive of pulmonary hemorrhage. The patient developed severe thrombocytopenia, disseminated intravascular coagulation, and respiratory failure and died despite intensive treatment. Autopsy revealed diffuse pulmonary hemorrhage, alveolar septal thickening, focal diffuse alveolar damage with hyaline membrane formation, and prominent hemophagocytosis. Immunohistochemical staining demonstrated numerous SFTS virus-infected cells within the lung tissue. This case highlights the CT findings of pulmonary involvement in fatal SFTS and demonstrates a direct radiologic-pathologic correlation. Our findings suggest that cytokine storm and hemophagocytic syndrome play critical roles in the development of pulmonary hemorrhage and lung injury in SFTS.</p>","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148708441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-pitch Low-dose Chest Computed Tomography With Calcium-aware Reconstruction for Coronary Artery Calcium Scoring: Accuracy and Dose Reduction.","authors":"He Zhang, Lulu Zhang, Zhen Wang, Juan Long, Xiaohan Liu, Meng Yu, Lixiang Xie, Tao Ding, Yankai Meng, Cunjie Sun, Kai Xu","doi":"10.1097/RTI.0000000000000900","DOIUrl":"https://doi.org/10.1097/RTI.0000000000000900","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the accuracy, radiation dose, and clinical feasibility of a high-pitch low-dose chest CT (Sa36LDCT) scanning protocol with calcium-aware reconstruction for coronary artery calcium scoring (CAC).</p><p><strong>Materials and methods: </strong>In this prospective study, 90 patients underwent both standard CAC scanning (Qr36CACS, 120 kVp) and Sa36LDCT (70 to 120 kVp, high-pitch, ATVS). CAC scoring was quantified as Agatston score, calcium volume, and equivalent mass. Risk stratification was assessed using Agatston categories. Agreement between protocols was evaluated using intraclass correlation coefficients, Bland-Altman analysis, and weighted kappa. Subgroup analyses were performed according to heart rate (≤75 vs. >75 bpm). Radiation dose and subjective image quality were also compared.</p><p><strong>Results: </strong>CAC metrics showed no significant difference between protocols, with excellent agreement (ICC = 0.983 to 0.996). Subgroup analysis revealed that heart rate did not significantly influence CAC quantification or risk classification, with Agatston score ICC values of 0.98 for ≤75 bpm and 0.99 for >75 bpm, demonstrating similar accuracy in both subgroups. Radiation dose reduction was consistently observed across both subgroups, with Sa36LDCT reducing effective radiation dose by 62% (0.74 vs. 0.28 mSv, P < 0.001), without compromising image quality. Risk stratification based on Agatston categories showed near-perfect consistency across heart rate subgroups (weighted k = 0.957).</p><p><strong>Conclusion: </strong>High-pitch Sa36LDCT provides accurate and reliable CAC scoring equivalent to standard CAC scoring, with substantial radiation dose reduction and preserved image quality. The protocol's robustness across heart rate subgroups demonstrates its potential as a safe and practical approach for combined pulmonary and cardiovascular screening, pending validation in larger, more diverse populations.</p>","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148702436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive Value of Imaging Indicators for Disease Progression in Acute Stanford Type B Aortic Intramural Hematoma Without Ulcer-like Lesions.","authors":"Yan Xu, Hui Xu, Nan Zhang, Yongxin Li, Erhui Zhang, Xin Zhao, Dongting Liu, Wenjing Zhao, Zehui Tang, Zhonghua Sun, Jiayi Liu, Zhaoying Wen","doi":"10.1097/RTI.0000000000000901","DOIUrl":"https://doi.org/10.1097/RTI.0000000000000901","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the clinical outcomes of acute Stanford type B intramural hematoma (TBIMH) without ulcer-like lesions following medical management and to identify predictors of disease progression.</p><p><strong>Materials and methods: </strong>A retrospective analysis was performed on patients with acute TBIMH without ulcer-like lesions who received medical management. Patients were categorized into progression and nonprogression groups based on 1-year follow-up computed tomography angiography (CTA). Disease progression was defined as aortic rupture, aortic dissection, aortic enlargement (≥5 mm), or hematoma thickening (≥3 mm), while nonprogression was defined as complete/partial resolution or retention of the hematoma. A multivariate analysis identified the predictors of disease progression, and Kaplan-Meier curves were used to compare survival outcomes.</p><p><strong>Results: </strong>A total of 110 patients (mean age 55.9±10.5 y, 25 females) were included, with 21 patients (19.1%) showing disease progression. Multivariate analysis revealed that the maximum aortic diameter (MAD) (OR=7.6, P=0.003) and maximum CT value of the hematoma (CTmax) (OR=1.04, P=0.025) were independently associated with disease progression. The optimal cutoff values for MAD and CTmax were 40.0 mm (AUC: 0.69, sensitivity: 38.1%, specificity: 92.1%) and 71.9 HU (AUC: 0.68, sensitivity: 76.2%, specificity: 66.3%), respectively. When MAD and CTmax were combined, the AUC increased to 0.75 (sensitivity: 81.0%, specificity: 66.3%).</p><p><strong>Conclusion: </strong>A model based on MAD and CTmax effectively stratifies progression risk in TBIMH without ulcer-like lesions, facilitating early intervention in high-risk patients.</p>","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148686308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of STING-Associated Vasculopathy of Infancy (SAVI) With Long-Term Chest CT Follow-Up.","authors":"Yo Todoroki, Tomoka Hirosawa, Akitaka Fujisaki, Yoshiko Hayashida, Shingo Nakayamada, Eisuke Katafuchi, Toshiyuki Nakayama, Takatoshi Aoki","doi":"10.1097/RTI.0000000000000897","DOIUrl":"https://doi.org/10.1097/RTI.0000000000000897","url":null,"abstract":"","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148671306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolving Indications, Technical Quality, Diagnostic Outcomes, and Utilization Patterns of Chest Magnetic Resonance Imaging: A Quaternary Care Center Experience With 3730 Patients Over 25 Years.","authors":"Bruno Hochhegger, Julio M F Zhang, Joao M da Fonseca, Liisa Bergmann, Jürgen Biederer, Stephan Altmayer, Daniela Hochhegger, Jeanne B Ackman","doi":"10.1097/RTI.0000000000000899","DOIUrl":"https://doi.org/10.1097/RTI.0000000000000899","url":null,"abstract":"<p><strong>Purpose: </strong>To characterize longitudinal trends in clinical indications, technical quality, diagnostic outcomes, and demographic patterns of chest magnetic resonance imaging (MRI) at a US quaternary care center over 25 years.</p><p><strong>Materials and methods: </strong>This institutional review board-approved retrospective cohort study analyzed 3730 consecutive chest MRI examinations performed between August 2001 and April 2026 at a US quaternary care academic medical center. Clinical indications and technical quality assessment were extracted from radiology report narratives, normalized, and classified into 7 major categories. Differences in indication and diagnosis distributions between cohorts were evaluated using the χ2 test; age was compared using the independent-samples t test.</p><p><strong>Results: </strong>A total of 3730 examinations were included (mean patient age 34.0 ± 23.4 y; 55.1% females). Annual volume peaked at 270 in 2012 with a resurgence to 172 in 2025. The share of vascular indications declined from 70.9% of early-era examinations (2001-2005) to 23.5% in the recent era (2020-2025), while oncologic indications increased from 10.9% to 36.8% (both P < 0.001). Confirmed aortic/vascular pathology fell from 17.3% to 2.1%; malignant diagnoses increased from 3.2% to 10.2% (P < 0.001). Documented motion artifact decreased from the early to recent era (5.3% vs. 3.3%; P = 0.046).</p><p><strong>Conclusions: </strong>Chest MRI utilization has shifted significantly over 25 years from predominantly vascular to oncology-driven indications, with stable diagnostic yield. Technical examination quality limitations were significantly more frequent during off-hours.</p>","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148671261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cine Magnetic Resonance Imaging for Assessing Chest Wall Invasion in Lung Cancer: A Systematic Review and Meta-Analysis.","authors":"Danilo de Oliveira Santana Ramos, Sarah Verdan Moreira, Meiri Andréia Maria da Silva, Marília da Cruz Fagundes, Luisa Leitão de Faria, Thiago de Gaultier Oliveira do Amarante de Paulo, Giovanni Brondani Torri, Stephan Philip Leonhardt Altmayer, Bruno Hochhegger","doi":"10.1097/RTI.0000000000000902","DOIUrl":"https://doi.org/10.1097/RTI.0000000000000902","url":null,"abstract":"<p><strong>Purpose: </strong>To conduct a meta-analysis assessing the effectiveness of cine MRI in evaluating tumor invasion of the chest wall, using surgical and histopathologic analysis as the reference standard.</p><p><strong>Materials and methods: </strong>This systematic review and meta-analysis was conducted following the recommendations of the Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy and Preferred Reporting Items for Systematic Reviews and Meta-Analysis for Diagnostic Test Accuracy (PRISMA-DTA) guidelines. The study protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO) under the registration number CRD420250654330.</p><p><strong>Results: </strong>Five prospective studies comprising 190 patients with suspected chest wall invasion were included. The pooled sensitivity of cine MRI for detecting chest wall invasion was 99% (95% CI: 34%-100%), with a specificity of 74% (95% CI: 64%-82%), a negative predictive value of 100% (95% CI: 52%-100%), and a positive predictive value of 50% (95% CI: 39%-61%). No substantial heterogeneity was observed across studies.</p><p><strong>Conclusions: </strong>Cine MRI showed high sensitivity and excellent negative predictive value for ruling out chest wall invasion in lung cancer. These findings suggest cine MRI may be a useful noninvasive tool for preoperative assessment, particularly in cases with inconclusive CT or static MRI; however, CIs were wide due to the limited evidence base. Conversely, when cine MRI suggests invasion, the modest specificity and positive predictive value highlight the importance of invasive confirmation before definitive therapeutic decisions. Further prospective, multicenter studies using standardized protocols are warranted to validate and expand its clinical application.</p>","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148664745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}