Kardiochirurgia I Torakochirurgia Polska最新文献

{"title":"Retention of temporary epicardial pacing wires: when migration causes dehiscence of a sternal wound.","authors":"Eleonora Latini, Dario Buioni, Paolo Nardi, Calogera Pisano, Cristina Viscogliesi, Federico Agneni, Claudia Altieri, Giovanni Ruvolo","doi":"10.5114/kitp.2023.129547","DOIUrl":"https://doi.org/10.5114/kitp.2023.129547","url":null,"abstract":"Address for correspondence: Dario Buioni, Cardiac Surgery Division, Tor Vergata University Hospital, Viale Oxford 81, Rome, PC 00133, Italy, e-mail: docyuk@libero.it Received: 14.02.2023, accepted: 5.03.2023. Temporary epicardial pacing wires (TEPWs) have been routinely inserted in all patients undergoing cardiac surgery since the 1960s. The main purposes were, and still are, therapeutic and diagnostic, as they are mainly used to recognize and treat ventricular and/or atrial rhythm disturbances that may be a complication of cardiac interventions and to sustain the possible hemodynamic instability during post-operative intensive care [1]. However, their necessity is often discussed as their use is linked to several but unlikely complications such as cardiac tamponade and hemorrhage at the time of removal [2], or infection, wound dehiscence and migration when retained [3]. The indications for insertion of the TEPWs are several: conduction abnormalities such as AV block, prolonged AV delay, bifascicular block; bradycardia and tachycardia, especially atrial fibrillation, which is common in the period following cardiac surgery; and the need to place both atrial and ventricular wires is often dependent on the patient; furthermore, the pacing system should be checked and reassessed routinely based on the patient’s condition. The removal must be done carefully by gentle and constant traction; if too much traction is needed as they may have been caught in a tight suture, they should be cut as close to the skin as possible due to the risk of tamponade immediately after the removal procedure. For this reason, it is necessary to observe the patient and perform echocardiography a few hours after the removal [1]. Although there is a risk of hemorrhage and cardiac tamponade, to cut the wires flush with the skin is not a procedure free of adverse events such as infection and migration. An 89-year-old woman with severe aortic stenosis and aneurysm of the ascending aorta, with medical history of hypertension, dyslipidemia, obesity and chronic renal failure, underwent aortic valve replacement with a Sorin Mitroflow 21 bioprosthesis and of the ascending aorta with an Intervascular 28 prosthesis, requiring circulatory arrest during the procedure on September 2014. In the immediate post-operative period, due to massive bleeding and hemodynamic instability, it became necessary to conduct a surgical revision of the mediastinum. Two right atrial and two right ventricular epicardial pacing wires were inserted at the moment of the intervention and were not removed during the revision of the mediastinum; on the 6th postoperative day (POD), at the time of removal, only the ones placed on the right ventricle were removed without resistance, while the ones on the right atrium were cut flush with the skin. On the 8th POD, the patient presented strong chest pain, erythema and drainage from the distal third of the sternotomy wound associated with sternal instability; on the 10th ","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"20 2","pages":"123-125"},"PeriodicalIF":0.7,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ae/16/KITP-20-51120.PMC10410639.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9978694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lung cancer invading the superior vena cava - surgical treatment. A short and up-to-date review.","authors":"Eleftherios Nikolaidis,&nbsp;Nikolaos Bolanos,&nbsp;Dimitrios Anagnostopoulos,&nbsp;Vasileios Leivaditis,&nbsp;Konstantinos Grapatsas,&nbsp;Efstratios Koletsis,&nbsp;Athanasios Papatriantafyllou,&nbsp;Ioannis Panagiotopoulos,&nbsp;Francesk Mulita,&nbsp;Nikolaos Baltayiannis,&nbsp;Manfred Dahm,&nbsp;Antonios Chatzimichalis","doi":"10.5114/kitp.2023.129546","DOIUrl":"https://doi.org/10.5114/kitp.2023.129546","url":null,"abstract":"<p><p>Lung cancer is one of the leading causes of cancer-related deaths worldwide. Superior vena cava syndrome (SVCS) is a rare but potentially life-threatening complication of lung cancer, occurring in approximately 5-10% of cases. There are difficulties in the process of surgical treatment of SVC infiltrated by lung tumors but the contribution of technological evolution and innovation is promising. At the same time, the amelioration of survival rates of patients subjected to surgical treatment is equally promising. The reported outcomes of surgical treatment for SVC invasion due to lung tumors vary depending on the extent of the tumor and the patient's overall health status. However, studies clearly suggest that surgical treatment can improve survival and quality of life in selected patients. The literature review showed that the surgical approach to lung cancer invading the SVC constitutes the most indispensable treatment which helps to achieve the long-term survival of patients.</p>","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"20 2","pages":"105-110"},"PeriodicalIF":0.7,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/46/KITP-20-51119.PMC10410641.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9978696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac angiosarcoma: a formidable challenge.","authors":"Daniele Trombetti,&nbsp;Calogera Pisano,&nbsp;Maria Sabrina Ferrante,&nbsp;Laura Asta,&nbsp;Claudia Altieri,&nbsp;Paolo Nardi,&nbsp;Dario Buioni,&nbsp;Giovanni Ruvolo","doi":"10.5114/kitp.2023.126101","DOIUrl":"https://doi.org/10.5114/kitp.2023.126101","url":null,"abstract":"Address for correspondence: Daniele Trombetti MD, Department of Cardiac Surgery, University of Tor Vergata, Rome, Italy, e-mail: daniele.trombetti@famigliatrombetti.it Received: 2.10.2022, accepted: 6.02.2023. Primary cardiac angiosarcoma (AS) is a clinically rare (incidence of about 0.017%) and highly invasive cardiac tumor with an unfavorable prognosis. The general prognosis of patients with primary cardiac sarcoma is poor, with median overall survival which ranges from 9 to 27 months in recent case series [1]. Cases of primary cardiac angiosarcoma (PCAS) are extraordinarily rare but represent most cases of malignant cardiac cancer. PCAS originates from vascular endothelial cells or vascular endothelial cells that have differentiated from mesenteric cells. Much of the literature indicates that a majority of PCAS cases occur in the right atrium. Cardiac sarcomas usually present insidious symptoms in young and middle-aged patients. They generally have an unfavorable prognosis with an overall survival of between 6 and 12 months. The treatment of choice for these rare malignancies is a combination of surgical resection and radioand/or chemotherapy [2]. However, in most cases, and in contrast to benign cardiac tumors, surgical resection still represents a palliative strategy for many patients with cardiac sarcomas. Therefore, rapid and accurate diagnosis is necessary and can confer a survival advantage on individual patients [3]. We report our experience with a young patient treated in our unit for an undifferentiated pleomorphic sarcoma who is still alive. As this study was carried out in order to improve the management of primary cardiac angiosarcoma, local approval at the level of the surgical department was obtained prior to data collection and the patient signed the consent form for scientific purposes. In April 2020, a 41-year-old patient was admitted to the Emergency Room of Tor Vergata University for dyspnea associated with chest tightness and vertigo. The echocardiography examination showed a round-shaped hyperechoic formation (6 × 4 cm) occupying all the left atrium until the inflow tract of the left ventricle with a large base of implantation in the anterior portion of the atrial septum (Figures 1 A–C). This mass engaged the mitral valve, resulting in severe steno-insufficiency (transvalvular medium gradient 27 mm Hg). A computed tomography (CT) raised the hypothesis of a PCAS (Figures 2 A–C). After a multidisciplinary clinical discussion, the patient was transferred to our Cardiac Surgery Unit for a cardiac operation. A standard longitudinal sternotomy was performed and the patient underwent cardiopulmonary bypass for exeresis of the mass. At the opening of the left atrium the mass adhered tenaciously to the atrial septum, the left auricle, the free wall of the left atrium and the anterior flap of the mitral valve. Despite the presence of tenacious adhesions of the mass to the atrial structures, it was possible to perform a total mass ex","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"20 1","pages":"53-56"},"PeriodicalIF":0.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b0/6e/KITP-20-50414.PMC10107413.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9377680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hybrid treatment of type 2 right sided aortic arch and Kommerell's diverticulum in an octogenarian.","authors":"Serkan Burc Deser","doi":"10.5114/kitp.2023.126103","DOIUrl":"https://doi.org/10.5114/kitp.2023.126103","url":null,"abstract":"","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"20 1","pages":"60-61"},"PeriodicalIF":0.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d3/df/KITP-20-50416.PMC10107421.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9377683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unilateral pulmonary edema following minimally invasive cardiac surgery: keeping both eyes <i>maximally</i> open.","authors":"Rohan Magoon,&nbsp;Nitin Choudhary,&nbsp;Jes Jose","doi":"10.5114/kitp.2023.126098","DOIUrl":"https://doi.org/10.5114/kitp.2023.126098","url":null,"abstract":"","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"20 1","pages":"45-46"},"PeriodicalIF":0.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/84/af/KITP-20-50411.PMC10107424.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9377684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical treatment of thoracic esophageal diverticula.","authors":"Janusz Wlodarczyk,&nbsp;Tomasz Smęder,&nbsp;Piotr Obarski","doi":"10.5114/kitp.2023.126091","DOIUrl":"https://doi.org/10.5114/kitp.2023.126091","url":null,"abstract":"<p><strong>Introduction: </strong>Thoracic esophageal diverticulum (TED) is a rare benign disease associated with motility disorders of the esophagus. Surgical management is usually the definitive treatment, with traditional excision of the diverticulum via thoracotomy and minimally invasive techniques being comparable and associated with a mortality rate of between 0 and 10%.</p><p><strong>Aim: </strong>To present the results of surgical treatment of patients with thoracic diverticula of the esophagus in a 20-year period.</p><p><strong>Material and methods: </strong>The study presents a retrospective analysis of the results of surgical management of patients with the thoracic esophageal diverticulum. All patients underwent open transthoracic diverticulum resection with myotomy. Patients were evaluated for the degree of dysphagia before and after surgery, associated complications and overall comfort after surgical treatment.</p><p><strong>Results: </strong>Twenty-six patients due to diverticula of the thoracic part of the esophagus underwent surgical treatment. Resection of the diverticulum with esophagomyotomy was performed in 23 (88.5%) patients, anti-reflux surgery was performed in 7 (26.9%) and in 3 (11.5%) patients with achalasia, the diverticulum was left unresected. Among the patients operated on, 2 (7.7%) patients developed a fistula, and both required mechanical ventilation. In 1 patient the fistula closed spontaneously, and the other patient required esophageal resection and colon reconstruction. Two patients required emergency treatment due to mediastinitis. There was no mortality in the perioperative period of hospital stay.</p><p><strong>Conclusions: </strong>Treatment of thoracic diverticula is a difficult clinical problem. Postoperative complications pose a direct threat to the patient's life. Esophageal diverticula is characterized by good long-term functional results.</p>","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"20 1","pages":"1-6"},"PeriodicalIF":0.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/93/7a/KITP-20-50404.PMC10107423.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9377679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of eversion carotid endarterectomy under local anesthesia and eversion/conventional carotid endarterectomy under general anesthesia.","authors":"Serkan Burc Deser,&nbsp;Berk Arapi","doi":"10.5114/kitp.2023.126096","DOIUrl":"https://doi.org/10.5114/kitp.2023.126096","url":null,"abstract":"<p><strong>Introduction: </strong>Studies searching outcomes of eversion carotid endarterectomy (E-CEA) under local anesthesia are lacking.</p><p><strong>Aim: </strong>To evaluate the postoperative outcomes of E-CEA under local anesthesia and compare it with E-CEA/Conventional CEA under general anesthesia in symptomatic or asymptomatic patients.</p><p><strong>Material and methods: </strong>From February 2010 to November 2018 a total of 182 patients (143 males, 39 females; mean age: 69.69 ±9.88 years; range: 47 to 92 years) who underwent eversion CEA or conventional CEA with patchplasty under general or local anesthesia in two tertiary centers were included in this study.</p><p><strong>Results: </strong>Overall in-hospital stay (<i>p</i> = 0.01), postoperative in-hospital stay (p = 0.022) took significantly less time in favor of E-CEA under local anesthesia. Overall, 6 patients developed major stroke (3.2%), among them 4 (2.1%) patients passed away, 7 (3.8%) patients developed cranial nerve injury (the marginal mandibular branch of the facial nerve and hypoglossal nerve), 10 (5.4%) patients developed a hematoma in the postoperative period. No difference was found in terms of postoperative stroke (<i>p</i> = 0.470), postoperative death (<i>p</i> = 0.703), postoperative bleeding rate (<i>p</i> = 0.521) or postoperative cranial nerve injury (<i>p</i> = 0.481) between the groups.</p><p><strong>Conclusions: </strong>The mean operation time, postoperative in-hospital stay, overall in-hospital stay, and need for shunting were lower in patients who underwent E-CEA under local anesthesia. E-CEA under local anesthesia seemed to do better in stroke, death, and bleeding rate, however, this difference was not significant.</p>","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"20 1","pages":"30-35"},"PeriodicalIF":0.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/33/a2/KITP-20-50409.PMC10107416.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9384310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic thymectomy: a review of techniques and results.","authors":"Danilo Coco,&nbsp;Silvana Leanza","doi":"10.5114/kitp.2023.126097","DOIUrl":"https://doi.org/10.5114/kitp.2023.126097","url":null,"abstract":"<p><p>Thymectomy is a well-established therapeutic option in the multidisciplinary treatment of nonthymomatous myasthenia gravis (MG) and in thymoma treatment. Although many surgical procedures for thymectomy have been identified, the transsternal method is still regarded as the gold standard. Minimally invasive procedures, on the other hand, have achieved popularity in the last decades and are now extensively used in this field of surgery. Among them, robotic thymectomy has been the most cutting-edge surgical procedure. Several authors and meta-analyses have shown that a minimally invasive approach to thymectomy is associated with improved surgical results and fewer complications in surgery compared to transsternal open thymectomy, without any substantial changes in myasthenia gravis complete rates of remission. Hence, in the present review of the literature, we aimed to describe and delineate the techniques, advantages, outcomes, and future perspectives of robotic thymectomy. Existing evidence suggests that robotic thymectomy will likely become the gold standard for thymectomy in early stage thymomas and MG subjects. Many of the drawbacks related to other minimally invasive procedures appear to be resolved by robotic thymectomy, and long-term neurological outcomes are satisfactory. In addition, improved vision and high dexterity of instrument movements enable safe and complete thymic tissue dissection, superior to standard thoracoscopic procedures. The access with minimally invasive surgery VATS (video-assisted thoracoscopic surgery) or RATS (robot-assisted thoracic surgery) access in its various variants allows the extent of mediastinal fat resection due to the possibility of ectopic thymic foci in the mediastinum determining the long-term outcome in the group of patients operated on for myasthenia gravis. However, it was recommended to carry out better designed, multi-centre, randomized studies to arrive at definitive conclusions on robotic thymectomy for thymomas and myasthenia gravis treatment.</p>","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"20 1","pages":"36-44"},"PeriodicalIF":0.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/85/72/KITP-20-50410.PMC10107420.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9383923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bibliometric spotlight on thoracic surgery specialization theses in Turkey.","authors":"İbrahim Sarbay,&nbsp;İsmail Sarbay","doi":"10.5114/kitp.2023.126093","DOIUrl":"https://doi.org/10.5114/kitp.2023.126093","url":null,"abstract":"<p><strong>Introduction: </strong>Scientific publications originating from medical specialty theses are seen as a start to an academic career for clinicians and a criterion to work in academia in Turkey.</p><p><strong>Aim: </strong>To evaluate thoracic surgery theses in the period 2001-2019 in publication and other bibliometric parameters.</p><p><strong>Material and methods: </strong>Our study investigated 319 theses prepared in the thoracic surgery field between January 2001 and December 2019 and registered in the National Thesis Center. We identified and recorded the author's gender, institution, research method, publication status, time, citations, journals' index, and author's order using Google Scholar, Web of Science Basic Search, and Master Journal List.</p><p><strong>Results: </strong>Of the 319 evaluated, 262 theses were from universities, and 57 were in Training and Research Hospitals. Thirty-two studies (10%) were experimental or prospective clinical. The number of published studies (38.5%) in journals was 123 (66 SCI/SCI-E, 8 ESCI, three other international indexes, and 46 national indexes). Sixty (18.8%) authors were women. The mean time to publication was 4.31 ±2.95 years. It was 3.3 years for female researchers (<i>p</i> = 0.029). Experimental/prospective studies in universities were relatively higher. The number of citations in SCI/SCI-E journals was significantly higher (<i>p</i> < 0.001). The time to the publication of experimental/prospective studies was shorter (<i>p</i> = 0.039).</p><p><strong>Conclusions: </strong>The publication rate of thoracic surgery theses was 38.5%. Female researchers published their studies earlier. Articles in SCI/SCI-E journals had a higher number of citations. The time to publication was significantly shorter in experimental/prospective studies. This study is the first in the literature as a bibliometric report of the thoracic surgery thesis.</p>","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"20 1","pages":"12-17"},"PeriodicalIF":0.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9e/f4/KITP-20-50406.PMC10107414.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9377685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treating Mitroflow dysfunction by means of an open valve-in-valve Perceval implantation.","authors":"Daniele Trombetti,&nbsp;Calogera Pisano,&nbsp;Claudia Altieri,&nbsp;Paolo Nardi,&nbsp;Sabrina Maria Ferrante,&nbsp;Laura Asta,&nbsp;Dario Buioni,&nbsp;Giovanni Ruvolo","doi":"10.5114/kitp.2023.126105","DOIUrl":"https://doi.org/10.5114/kitp.2023.126105","url":null,"abstract":"","PeriodicalId":49945,"journal":{"name":"Kardiochirurgia I Torakochirurgia Polska","volume":"20 1","pages":"65-66"},"PeriodicalIF":0.7,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/28/4f/KITP-20-50418.PMC10107412.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9383924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}