Luminescence最新文献_第8页

A label-free and signal-amplifiable fluorescent biosensor based on aptamer-conjugated gold nanoparticles and hybridization chain reaction for determination of carcinoembryonic antigen 一种用于检测癌胚抗原的基于适配体结合金纳米粒子和杂交链反应的无标记、可放大信号的荧光生物传感器

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-16 DOI: 10.1002/bio.4899

Siyao Liu, Xingjie Yang, Peng Xiao, Wei Wang, Shaoqing Zhu, Jingzhi Chu, Chenguang Zhou

{"title":"A label-free and signal-amplifiable fluorescent biosensor based on aptamer-conjugated gold nanoparticles and hybridization chain reaction for determination of carcinoembryonic antigen","authors":"Siyao Liu, Xingjie Yang, Peng Xiao, Wei Wang, Shaoqing Zhu, Jingzhi Chu, Chenguang Zhou","doi":"10.1002/bio.4899","DOIUrl":"https://doi.org/10.1002/bio.4899","url":null,"abstract":"The sensitive detection of cancer biomarkers is crucial for early accurate diagnostics and therapy of cancer patients. Carcinoembryonic antigen (CEA) is a tumor-associated antigen derived from colon cancer and embryonic tissues. In this study, we have developed a label-free fluorescence biosensing platform for the quantification of CEA with the “turn-on” signal output. This platform employs a label-free strategy that incorporates an aptamer-modified gold nanoparticle (Apt@AuNP) probe for the recognition of CEA, in combination with hybridization chain reaction (HCR) amplification. In the presence of target CEA, Apt@AuNPs selectively capture CEA, resulting in a reduction of subsequent complementary chains (CP) binding on Apt@AuNPs. The remaining CP, acting as the initiator sequence for HCR, triggers the HCR, leading to the formation of abundant G-quadruplex structures. By employing Thioflavin T (ThT) for the formation of G-quadruplex/ThT complexes, the biosensor exhibits a significant enhancement of the fluorescence signal. Under optimized conditions, the biosensor platform demonstrates a limit of detection of 0.03 nM and a linear range from 0.1 to 2.5 nM. Additionally, the specificity investigation reveals the high selectivity of this fluorescent biosensor. Finally, the performance of this method has been validated by successfully detecting CEA in real-life samples, highlighting its potential for clinical applications.","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"39 9","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142244517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of strontium aluminate-printed nonwoven fabric from recycled cotton cellulose for smart wearable photochromic applications 利用回收棉纤维素开发铝酸锶印刷无纺布，用于智能可穿戴光致变色应用

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-13 DOI: 10.1002/bio.4903

Salhah D. Al-Qahtani, Yasser A. Attia, Ghadah M. Al-Senani

{"title":"Development of strontium aluminate-printed nonwoven fabric from recycled cotton cellulose for smart wearable photochromic applications","authors":"Salhah D. Al-Qahtani, Yasser A. Attia, Ghadah M. Al-Senani","doi":"10.1002/bio.4903","DOIUrl":"https://doi.org/10.1002/bio.4903","url":null,"abstract":"Smart photochromic and fluorescent textile refers to garments that alter their colorimetric properties in response to external light stimulus. Cotton fibers have been reported as a main resource for many textile and non-textile industries, such as automobiles, medical devices, and furniture applications. Cotton is a natural fiber that is distinguished with breathability, softness, cheapness, and highly absorbent. However, there have been growing demands to find other resources for cotton textiles at high quality and low cost for various applications, such as sensor for harmful ultraviolet radiation. Herein, we present a novel method toward luminescent and photochromic nonwoven textiles from recycled cotton waste. Using the screen-printing technology, a cotton fabric that is both photochromic and fluorescent was developed using aqueous inorganic phosphor nanoparticles (10–18 nm)-containing printing paste. Both CIE Lab color coordinates and photoluminescence spectra showed that the transparent film printed on the nonwoven fabric develops a reversible green emission (519 nm) under ultraviolet light (365 nm), even at low pigment concentration (2%) in the printing paste. Colorfastness of printed fabrics showed high durability and photostability.","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"39 9","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142230967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultra-sensitive electrochemical immunosensor based on 2D vanadium diselenide (VSe2) for efficient detection of pathogens: Salmonella Typhimurium 基于二维二硒化钒 (VSe2) 的超灵敏电化学免疫传感器，用于高效检测病原体：鼠伤寒沙门氏菌

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-13 DOI: 10.1002/bio.4896

Rim M. Alsharabi, Jay Singh, Preeti S. Saxena, Anchal Srivastava

{"title":"Ultra-sensitive electrochemical immunosensor based on 2D vanadium diselenide (VSe2) for efficient detection of pathogens: Salmonella Typhimurium","authors":"Rim M. Alsharabi, Jay Singh, Preeti S. Saxena, Anchal Srivastava","doi":"10.1002/bio.4896","DOIUrl":"https://doi.org/10.1002/bio.4896","url":null,"abstract":"Layered transition metal dichalcogenides (TMDs), with an extensive surface area, intriguing tunable electrical and optical features, and a distinctive Van der Waals layered structure, yield outstanding sensing properties. Essentially, most TMDs originally existed in the crystallographic phase of a 2H trigonal prismatic structure, which is semiconducting in nature with poor electrocatalytic activity. In contrast, vanadium diselenide (VSe2) with its metastable metallic 1 T octahedral crystal structure has been proven to be an outstanding electrode material, embracing exceptional electrocatalytic behavior for various electrochemical (EC) applications. However, practically, VSe2 has hardly ever been explored in the field of biosensing technology. This study presents a novel EC biosensor based on the antibody of Salmonella Typhimurium (Anti-ST) immobilized on VSe2-supported Indium tin oxide (Anti-ST/VSe2/ITO) for quantitative and efficient Salmonella Typhimurium (ST) detection. The Anti-ST/VSe2/ITO bioelectrode displayed a linear relationship with ST concentration (1.3 × 10–107 CFU/ml) with a limit of detection (LOD) (0.096 CFU/ml) that is lower than previously reported ST biosensors and impressively high sensitivity (0.001996 μA.mL/CFU). Furthermore, the proposed electrode's electroanalytical activity was evaluated in spiked sugarcane juice, demonstrating distinguished applicability for specific ST detection in real samples.","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"39 9","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142230957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rice straw waste-based green synthesis and characterizations investigation of Fe-MoS2-derived nanohybrid 基于稻草废弃物的 Fe-MoS2 衍生纳米杂化物的绿色合成与表征研究

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-11 DOI: 10.1002/bio.4884

Anjali Singh, Magan Himanshu, Bhawna Verma, Asad Syed, Abdallah M. Elgorban, Ling Shing Wong, Basant Lal, Rajeev Singh, Neha Srivastava

{"title":"Rice straw waste-based green synthesis and characterizations investigation of Fe-MoS2-derived nanohybrid","authors":"Anjali Singh, Magan Himanshu, Bhawna Verma, Asad Syed, Abdallah M. Elgorban, Ling Shing Wong, Basant Lal, Rajeev Singh, Neha Srivastava","doi":"10.1002/bio.4884","DOIUrl":"https://doi.org/10.1002/bio.4884","url":null,"abstract":"In present work, synthesis of a nanohybrid material using Fe and MoS2 has been performed via a cost-effective and environmentally friendly route for sustainable manufacturing innovation. Rice straw extract was prepared and used as a reducing and chelating agent to synthesize the nanohybrid material by mixing it with molybdenum disulfide (MoS2) and ferric nitrate [Fe (NO3)3.9H2O], followed by heating and calcination. The X-ray diffraction (XRD) pattern confirms the formation of a nanohybrid consisting of monoclinic Fe2(MoO4)3, cubic Fe2.957O4, and orthorhombic FeS with 86% consisting of Fe2(MoO4)3. The properties were analyzed through Fourier-transformed infrared spectroscopy (FTIR), atomic force microscopy (AFM), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The results of the dynamic light scattering (DLS) study revealed a heterogeneous size distribution, with an average particle size of 48.42 nm for 18% of particles and 384.54 nm for 82% of particles. Additionally, the zeta potential was measured to be −18.88 mV, suggesting moderate stability. X-ray photoelectron spectroscopy (XPS) results confirmed the presence of both Fe2+ and Fe3+ oxidation states along with the presence of Molybdenum (Mo), oxygen (O), and Sulphur (S). The prepared nanohybrid material exhibited a band gap of 2.95 eV, and the photoluminescence intensity increased almost twice that of bare MoS2. The present work holds potential applications in photo luminescent nanoplatform for biomedical applications.","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"39 9","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142170016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biological synthesis of silver nanoparticles using Senna auriculata flower extract for antibacterial activities 利用番泻叶花提取物生物合成银纳米粒子以提高抗菌活性

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-11 DOI: 10.1002/bio.4894

Rethinavelu Renuka, Thirugnanam Thilagavathi, Adaikkalam Dhanalakshmi, Ramamurthy Uthrakumar, Kasinathan Kaviyarasu, Manesh Ashok Yewale, Mohammed Alsawat, Hassan S. Al Qahtani, Mir Waqas Alam

{"title":"Biological synthesis of silver nanoparticles using Senna auriculata flower extract for antibacterial activities","authors":"Rethinavelu Renuka, Thirugnanam Thilagavathi, Adaikkalam Dhanalakshmi, Ramamurthy Uthrakumar, Kasinathan Kaviyarasu, Manesh Ashok Yewale, Mohammed Alsawat, Hassan S. Al Qahtani, Mir Waqas Alam","doi":"10.1002/bio.4894","DOIUrl":"https://doi.org/10.1002/bio.4894","url":null,"abstract":"In this study, biological synthesis of silver nanoparticles (AgNPs) using Senna auriculata flower extract for antibacterial activities was reported. The silver spectra compared to the plant extract show a rightward shift in AgNP peaks, indicating successful nanoparticle formation. The absorption band at 302 nm and the disappearance or shift of other peaks further confirm the synthesis. X-ray diffraction (XRD) analysis reveals that the AgNPs synthesized with S. auriculata extract have an average crystallite size of 25 nm. Transmission electron microscopy (TEM) results exhibited a polydispersed, spherical shape with sizes ranging from 70 nm, in clear contrast to the electron microscope image that showed their spherical shape. When examining the selected area electron diffraction (SAED) image, a specific set of lattice planes was correlated with a specific spot. A histogram of AgNP particle size distribution can be seen. AgNPs were tested against four different strains of bacteria for their antibacterial effectiveness, including gram negative bacteria (Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus), as well as gram positive bacteria (S. aureus, d. Bacillus subtilis), at various concentrations of AgNP. The results of in vitro experiments indicate that AgNPs containing S. auriculata flowers inhibit amylase well. At two concentrations, ~16.03% and ~70.99%, AgNPs inhibit the reaction at low and high concentrations, respectively.","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"39 9","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142170110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

pH-responsive persistent luminescence nanoprobes biosensor for autofluorescence-free determination of glucose level in human samples and fingerprint encryption 用于无自发荧光测定人体样本中葡萄糖含量和指纹加密的 pH 响应型持久发光纳米探针生物传感器

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-11 DOI: 10.1002/bio.4900

Xiaohu Ma, Runzhi Zhu, Hui Zhang, Zhe Meng

{"title":"pH-responsive persistent luminescence nanoprobes biosensor for autofluorescence-free determination of glucose level in human samples and fingerprint encryption","authors":"Xiaohu Ma, Runzhi Zhu, Hui Zhang, Zhe Meng","doi":"10.1002/bio.4900","DOIUrl":"https://doi.org/10.1002/bio.4900","url":null,"abstract":"Glucose level is an important indicator of diabetes, and maintaining an appropriate physiological concentration of glucose is important for human health. However, traditional optical sensors are interfered by the interference of strong background autofluorescence and natural responsive luminescence, which severely limits their application in complex biological samples. Herein, as a novel glucose biosensing probe, green-emitting Zn2GeO4:Mn2+, Eu3+ (ZGME) persistent luminescence nanoparticles (PLNPs) with pH stimulus-responsive was prepared by a facile one-pot hydrothermal method. We also investigated the pH stimulus-responsive luminescence behaviour of ZGME over a range of pH values from 2.8 to 8.0. Taking advantage of the interesting property that ZGME photoluminescence intensity has a pH response, within an extraordinarily narrow pH range of 5.0–6.5 for highly selectivity and sensitive determination of glucose level in human samples by acid-responsive quenching and persistent luminescent performance. The detection results show high accuracy of the measured values of glucose in serum with a wide detection range (2.5 μg L−1-10 mg L−1) and low detection limit (0.5 μg L−1). Finally, the pH-responsive persistent luminescence also makes ZGME promising for high-level fingerprint information encryption. Hence, the established pH stimulation-responsive PLNPs-based biosensing probe offers excellent performance with high selective, accuracy and signal-to-noise ratio for detection of glucose level in human samples.","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"39 9","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142170111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimization of Rhizoclonium hieroglyphicum extract for enhanced synthesis of nickel oxide nanoparticles using response surface methodology and its potential exploration in biological application 利用响应面方法优化根瘤蚜提取物以增强氧化镍纳米粒子的合成及其在生物应用中的潜力挖掘

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-10 DOI: 10.1002/bio.4893

Ammapettai Varanavasu Swathilakshmi, Gunaseelan Vivekananth Geethamala, Saad Aldawood, Nachimuthu Kavipriya, Senniappan Kokilaselvi, Pechimuthu Chitra, Thangaswamy Selvankumar, Mani Poonkothai

{"title":"Optimization of Rhizoclonium hieroglyphicum extract for enhanced synthesis of nickel oxide nanoparticles using response surface methodology and its potential exploration in biological application","authors":"Ammapettai Varanavasu Swathilakshmi, Gunaseelan Vivekananth Geethamala, Saad Aldawood, Nachimuthu Kavipriya, Senniappan Kokilaselvi, Pechimuthu Chitra, Thangaswamy Selvankumar, Mani Poonkothai","doi":"10.1002/bio.4893","DOIUrl":"https://doi.org/10.1002/bio.4893","url":null,"abstract":"The study investigates the potential of Rhizoclonium hieroglyphicum as a novel source for synthesizing nickel oxide nanoparticles (RH-NiONPs) and evaluates its biological applications. Phytochemicals in the algal extract serve as capping, reducing and stabilizing agent for nickel oxide nanoparticles. The process variables were optimized using BBD based RSM to obtain maximum RH-NiONPs. Characterization of RH-NiONPs using UV–Vis and FT-IR spectroscopy reveals the plasmon resonance peak at 340 nm and the functional groups responsible for reduction and stabilization. XRD confirmed the crystalline nature while the stability and size of the RH-NiONPs were determined by DLS and zeta potential. Toxicity assessments demonstrated the effect of RH-NiONPs against Vigna radiata, Allium cepa and Artemia salina was low. RH-NiONPs revealed significant zone of inhibition against the selected bacteria and fungi. The results of larvicidal activity showed that RH-NiONPs are toxic to 4th instar larvae of Daphnis nerii. Also, RH-NiONPs efficiently decolorized Reactive Violet 13 (92%) under sunlight irradiation and the experimental data well fits to Langmuir isotherm along with pseudo second order kinetic model. The thermodynamic studies enunciate the exothermic and non-spontaneous photocatalytic decolorization of reactive violet 13. Thus, the current study assesses the eco-friendly and cost-effective nature of RH-NiONPs along with its biological applications.","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"39 9","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142165633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improvement of fluorescence properties by surface modification of CdS-ZnS quantum dots by thiol compounds and its application as a sensitive fluorescence probe for copper ion detection 硫醇化合物对 CdS-ZnS 量子点的表面修饰及其作为灵敏荧光探针在铜离子检测中的应用改善了其荧光特性

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-10 DOI: 10.1002/bio.4874

Seyfollah Ghasemi, Abdolraouf Samadi-Maybodi

{"title":"Improvement of fluorescence properties by surface modification of CdS-ZnS quantum dots by thiol compounds and its application as a sensitive fluorescence probe for copper ion detection","authors":"Seyfollah Ghasemi, Abdolraouf Samadi-Maybodi","doi":"10.1002/bio.4874","DOIUrl":"https://doi.org/10.1002/bio.4874","url":null,"abstract":"The capped CdS-ZnS quantum dots (QDs) were synthesized with various thiol capping agents of glycolic acid (TGA), mercaptosuccinic acid (MSA), and L-cysteine (LCY) and used as fluorescence probe for determination of Cu (II) ions. The method of two-level three-factor full-factorial experiment design was used to achieve the best optical fluorescence emission. Results revealed that Cu (II) ions can effectively quench the emission of QDs, and the fluorescence intensity is linearly decreased with increasing Cu (II) ion concentration. The limit of detection for CdS-ZnS@ QDs capped with TGA, MSA, and LCY was obtained at 1.15 × 10−7, 1.32 × 10−7, and 2.19 × 10−7 mol L−1, respectively, with linear dynamic range of 3.13 × 10−6 to 1.41 × 10−4 mol L−1. Luminescence quantum yields of CdS-ZnS@LCY, CdS-ZnS@MSA, and CdS-ZnS@TGA were obtained at 4.17, 1.92, and 2.47, respectively. Results indicated that no significant quenching occurred in the presence of the other metal ions. The binding constant (Kb) of capped CdS-ZnS@ QDs with Cu2+ and the other metal ions was also investigated and discussed. The Kb value for Cu2+ was obtained considerably more than that the other ions. This work presents a new and sensitive method for determination of Cu2+ ion.","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"39 9","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142165634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Facile, eco-friendly and sensitive fluorimetric approach for detection of chlorpromazine: Application in biological fluids and tablet formulations as well as greenness evaluation of the analytical method 简便、环保、灵敏的荧光法检测氯丙嗪：生物液体和片剂中的应用以及分析方法的绿色评估

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-09 DOI: 10.1002/bio.4897

Islam M. Mostafa, Abobakr A. Mohamed, Yaser Alahmadi, Ahmed M. Shehata, Mohannad A. Almikhlafi, Mahmoud A. Omar

{"title":"Facile, eco-friendly and sensitive fluorimetric approach for detection of chlorpromazine: Application in biological fluids and tablet formulations as well as greenness evaluation of the analytical method","authors":"Islam M. Mostafa, Abobakr A. Mohamed, Yaser Alahmadi, Ahmed M. Shehata, Mohannad A. Almikhlafi, Mahmoud A. Omar","doi":"10.1002/bio.4897","DOIUrl":"https://doi.org/10.1002/bio.4897","url":null,"abstract":"Monitoring antipsychotic drugs in biological fluids, such as human serum and urine, is important for ensuring the safety and efficacy of psychiatric treatments. This process helps maintain therapeutic drug levels, minimize side effects, and optimize patient well-being. Chlorpromazine (CZ) is a widely prescribed antipsychotic drug used for conditions like schizophrenia, bipolar disorder, and acute psychosis. Almost all existing sensing techniques for CZ are either insensitive spectrophotometric methods or involve long and complex chromatographic procedures, limiting their routine use. In this work, we introduce a facile, green, and sensitive fluorimetric strategy with high reproducibility for detecting CZ in its pure form, tablet formulation, and spiked human plasma and urine without the need for derivatization reactions. The proposed method relies on the inhibition of the intramolecular photoinduced electron transfer (PET) effect by using 2.0 M acetic acid. This approach enables the linear detection of CZ from 3.0 to 600 ng/mL with remarkably low quantitation and detection limits of 1.51 and 0.49 ng/mL, respectively. Moreover, the developed method's greenness was evaluated.","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"39 9","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142165235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Europium (III)-modified sunflower-derived carbon dots for fluorescent anti-counterfeiting inks and photocatalysis 用于荧光防伪油墨和光催化的铕 (III) 改性向日葵衍生碳点。

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-08 DOI: 10.1002/bio.4872

Kunyu Chu, Congling Wang, Xuemin Cui

引用次数: 0