Luminescence最新文献_第9页

Near infrared aggregation-induced emission fluorescent materials for lipid droplets testing and photodynamic therapy 用于脂滴检测和光动力疗法的近红外聚集诱导发射荧光材料。

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-06 DOI: 10.1002/bio.4885

Jiang Wu, Yao Zhang, Xiaoxiao Wu, Tu Chen, Miao Yan, Shijing Shi, Fei Zhang, Baolei Fan, Baoqing Zhao, Hong Cheng

引用次数: 0

Derivatization-free sustainable spectrofluorimetric estimation of antihistamine drug mizolastine in pharmaceutical and biological matrices 药物和生物基质中抗组胺药物咪唑司汀的无衍生化可持续光谱荧光测定法。

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-06 DOI: 10.1002/bio.4888

Abobakr A. Mohamed, Mahmoud A. Omar, Abdallah M. Zeid, Mohamed Ibrahim Halawa, Islam M. Mostafa

{"title":"Derivatization-free sustainable spectrofluorimetric estimation of antihistamine drug mizolastine in pharmaceutical and biological matrices","authors":"Abobakr A. Mohamed, Mahmoud A. Omar, Abdallah M. Zeid, Mohamed Ibrahim Halawa, Islam M. Mostafa","doi":"10.1002/bio.4888","DOIUrl":"10.1002/bio.4888","url":null,"abstract":"Mizolastine is an antihistamine drug that is commonly used for treatment of chronic urticaria and allergic rhinitis. In this study, a facile, rapid, and sustainable fluorimetric method was established for the estimation of mizolastine in pharmaceutical and biological matrices for the first time. The approach methodology relied on the direct assessment of mizolastine's intrinsic fluorescence at 313 nm after excitation at 272 nm. This intrinsic fluorescence, stemming from the benzimidazole fluorophore moiety in mizolastine structure, serves as a distinctive marker for its precise quantification in the spiked human plasma and pharmaceutical formulations with high %recovery. The method exhibits reasonable sensitivity with lower limits of detection and quantification of 5.4 and 16.6 ng mL−1, respectively, across a concentration range of 25.0–2000.0 and 50–1000 ng mL−1 for the standard mizolastine analysis and mizolastine assay in the plasma sample, respectively. Moreover, the established method was applied to assess tablet content uniformity and mizolastine assay in plasma samples with high recoveries (98.50%–100.20%). Such applications underscore the method's potential applicability within quality control laboratories, preventing the need for sample preparation or laborious extraction steps. Finally, the method's sustainability and practicality were confirmed by applying different greenness and whiteness metrics, yielding excellent results.","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"39 9","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fabrication of highly fluorescent graphene quantum dots for quantification of As3+ ion using modified cellulose paper 利用改性纤维素纸制作用于定量 As3+ 离子的高荧光石墨烯量子点。

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-06 DOI: 10.1002/bio.4895

Jigna R. Bhamore, Jinsoo Park, Suresh Kumar Kailasa, Tae Jung Park

引用次数: 0

Prominently selective fluorescence approach with distinctive biopharmaceutical utility for analysis of lurasidone in human plasma and urine: Application to in vitro dissolution and content uniformity testing 用于分析人血浆和尿液中鲁拉西酮的具有显著生物制药用途的选择性荧光方法：应用于体外溶出度和含量均匀性测试。

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-06 DOI: 10.1002/bio.4887

Yasmeen E. Mostafa, Mohammed El-Sayed Metwally, Fawzi Elsebaei

{"title":"Prominently selective fluorescence approach with distinctive biopharmaceutical utility for analysis of lurasidone in human plasma and urine: Application to in vitro dissolution and content uniformity testing","authors":"Yasmeen E. Mostafa, Mohammed El-Sayed Metwally, Fawzi Elsebaei","doi":"10.1002/bio.4887","DOIUrl":"10.1002/bio.4887","url":null,"abstract":"A relevant approach based on the attractive inherited merits of fluorescence spectroscopy has been established for quantitative estimation of a newly approved second-generation atypical antipsychotic lurasidone (LUR) in its raw materials and pharmaceutical dosage forms. This study brings to light the strong native fluorescence of LUR at 400 nm in water after excitation at 316 nm. Different experimental parameters that may compromise the fluorescence of the drug were carefully investigated and optimized. A linear response was established between the relative fluorescence intensity and concentration over the concentration range of 50–650 ng/mL with excellent correlation (r = 0.9998). The validity of the method was evidenced in accordance with International Council for Harmonization guidelines, with minimal detection and quantification limits of 2.88 and 8.73 ng/mL, respectively. The method was effectively applied for the estimation of LUR in spiked human plasma and urine samples with acceptable recoveries. The biopharmaceutical significance of the method was heightened by its successful applications for both content uniformity and in vitro dissolution testing. Three different tools accredited the greenness character of the presented study. Eco-friendliness, effortlessness, and cost effectiveness are crucial hallmarks of our study. The presented study demonstrates potential applicability in quality control laboratories with limited resources.","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"39 9","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diesters of monoimide of perylene-3,4,9,10-tetracarboxylic acid — Synthesis, characterization, and application for dyeing polyester fibre, polystyrene, and poly (methyl methacrylate) films 过烯-3,4,9,10-四羧酸单亚胺二酯--合成、表征及在聚酯纤维、聚苯乙烯和聚（甲基丙烯酸甲酯）薄膜染色中的应用。

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-05 DOI: 10.1002/bio.4890

Joanna Paluszkiewicz, Aleksandra Grzelakowska, Joanna Rutowicz

引用次数: 0

Biogenic synthesis and characterization of silver nanoparticles (AgNPs) from aqueous extract of Lepidagathis cristata along with their antibacterial and antineoplastic activity to combat breast cancer cells (MCF-7) 从 Lepidagathis cristata 的水提取物中生物合成银纳米粒子 (AgNPs) 并确定其特性，同时确定其抗菌和抗肿瘤活性，以对抗乳腺癌细胞 (MCF-7)。

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-04 DOI: 10.1002/bio.4891

Punithavathi Manogaran, Prabu Krishnamoorthy, Sivakumar Murugesan, Devi Vijayavarma, Mysoon M. Al-Ansari, Kavitharani Mari, Nikolai Ivanovich Vatin, Sabari Vijayakumar

{"title":"Biogenic synthesis and characterization of silver nanoparticles (AgNPs) from aqueous extract of Lepidagathis cristata along with their antibacterial and antineoplastic activity to combat breast cancer cells (MCF-7)","authors":"Punithavathi Manogaran, Prabu Krishnamoorthy, Sivakumar Murugesan, Devi Vijayavarma, Mysoon M. Al-Ansari, Kavitharani Mari, Nikolai Ivanovich Vatin, Sabari Vijayakumar","doi":"10.1002/bio.4891","DOIUrl":"10.1002/bio.4891","url":null,"abstract":"Lepidagathis cristata (L. cristata) plant produces reducing and capping agents; this study utilized microwave-assisted biogenic synthesis to manufacture silver nanoparticles (AgNPs) using this plant. The structure, morphology, and crystallinity phases of prepared nanoparticles (NPs) were characterized by ultraviolet–visible spectroscopy (UV-viz), powder X-ray diffraction (XRD), Fourier-transform infrared (FTIR) spectroscopy, and scanning electron microscopy (SEM). Biologically synthesized AgNPs were treated against pathogenic bacteria species including Escherichia coli (E. coli), Bacillus subtilis (B. subtilis), and Staphylococcus aureus (S. aureus) and its highest zone of inhibition 10 ± 1.45 mm, 10 ± 0.74 mm, and 6 ± 0.43 mm, respectively, at the concentration of 100 μg/mL. The cytotoxic activity of AgNPs against MCF-7 breast cancer cells revealed significant growth inhibition by inhibiting cell viability, inhibitory concentration of 50% (IC50) of NPs observed at 55.76 μg/mL concentration. Finally, our findings concluded that the L. cristata-mediated biosynthesized AgNPs proved its potential antibacterial and neoplastic properties against MCF cells by endorsing the inhibition of cell proliferation especially with low concentration.","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"39 9","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and characterization of fluorinated graphene oxide nanosheets derived from Lissachatina fulica snail mucus and their biomedical applications 从 Lissachatina fulica 蜗牛粘液中提取的含氟氧化石墨烯纳米片的合成和表征及其生物医学应用。

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-04 DOI: 10.1002/bio.4875

Manimegalai Ganesan, Chandran Muthaiah, Mohammad Ahmad Wadaan, Manimaran Kumar, Dede Heri Yuli Yanto, Selvaraj Kumar, Thangasamy Selvankumar, Arunachalam Arulraj, Ramalinga Viswanathan Mangalaraja, Sanjeevamuthu Suganthi

{"title":"Synthesis and characterization of fluorinated graphene oxide nanosheets derived from Lissachatina fulica snail mucus and their biomedical applications","authors":"Manimegalai Ganesan, Chandran Muthaiah, Mohammad Ahmad Wadaan, Manimaran Kumar, Dede Heri Yuli Yanto, Selvaraj Kumar, Thangasamy Selvankumar, Arunachalam Arulraj, Ramalinga Viswanathan Mangalaraja, Sanjeevamuthu Suganthi","doi":"10.1002/bio.4875","DOIUrl":"10.1002/bio.4875","url":null,"abstract":"The modern nanomedicine incorporates the multimodal treatments into a single formulation, offering innovative cancer therapy options. Nanosheets function as carriers, altering the solubility, biodistribution, and effectiveness of medicinal compounds, resulting in more efficient cancer treatments and reduced side effects. The non-toxic nature of fluorinated graphene oxide (FGO) nanosheets and their potential applications in medication delivery, medical diagnostics, and biomedicine distinguish them from others. Leveraging the unique properties of Lissachatina fulica snail mucus (LfSM), FGO nanosheets were developed to reveal the novel characteristics. Consequently, LfSM was utilized to create non-toxic, environmentally friendly, and long-lasting FGO nanosheets. Ultraviolet–visible (UV–vis) spectroscopy revealed a prominent absorbance peak at 235 nm. The characterization of the synthesized FGO nanosheets involved X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), Raman, scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), high-resolution transmission electron microscopy (HR-TEM), and atomic force microscopy (AFM) analyses. The antimicrobial activity data demonstrated a broad spectrum of antibacterial effects against Escherichia coli, Bacillus subtilis, Klebsiella pneumoniae, and Pseudomonas aeruginosa. The cytotoxicity efficacy of LfSM-FGO nanosheets against pancreatic cancer cell line (PANC1) showed promising results at low concentrations. The study suggests that FGO nanosheets made from LfSM could serve as alternate factors for in biomedical applications in the future.","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"39 9","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inorganic nanoparticles: An effective antibiofilm strategy 无机纳米粒子：一种有效的抗生物膜策略

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-02 DOI: 10.1002/bio.4878

Shruti Nandkishor Tanwar, Yatish Ratn Parauha, Yogesh There, Faud Ameen, Sanjay Janraoji Dhoble

引用次数: 0

P-doped carbon dot nano-probe for inner filter effect–based determination of sarecycline in pharmaceutical dosage form and human plasma 基于内滤器效应的 P 掺杂碳点纳米探针用于测定药物剂型和人体血浆中的沙瑞环素。

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-02 DOI: 10.1002/bio.4889

Eman A. Elshenawy, Mohamed G. Yassin, Aya A. Marie

{"title":"P-doped carbon dot nano-probe for inner filter effect–based determination of sarecycline in pharmaceutical dosage form and human plasma","authors":"Eman A. Elshenawy, Mohamed G. Yassin, Aya A. Marie","doi":"10.1002/bio.4889","DOIUrl":"10.1002/bio.4889","url":null,"abstract":"Based on novel phosphorus-doped carbon dots (PCDs), a simple, quick, and accurate fluorescence probe for sarecycline (SAR) determination has been created. The PCDs were prepared in just five minutes using green, straightforward one-step microwave pyrolysis. To create the PCD probe, sodium phosphate monobasic was utilized as a phosphorus dopant and citric acid as a carbon supply. The proposed synthesis method was energy efficient and yielded CDs with a narrow particle size distribution. Based on inner-filter effect mechanism, the generated PCDs were used as nano-probe for SAR determination. The fluorescence quenching intensity showed a strong linear relationship with SAR concentration in the 3–90-μM range with a detection limit of 0.88 μM. Because there is no surface alteration of the CDs or creation of a covalent bond between SAR and PCDs, the developed approach is quick, easy, inexpensive, and requires less time. The new probe's enhanced sensitivity, broad linear range, and acceptable selectivity made it suitable for SAR measurement in pharmaceutical formulations and spiked human plasma. Most importantly, the Green Analytical Procedure Index (GAPI) and Analytical GREEnness (AGREE) assessments showed that the suggested method was environmentally friendly.","PeriodicalId":49902,"journal":{"name":"Luminescence","volume":"39 9","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142120987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association mechanism of bicalutamide and human serum albumin for potential clinical implications 比卡鲁胺与人血清白蛋白的关联机制及其潜在的临床意义。

IF 3.2 4区化学

Luminescence Pub Date : 2024-09-02 DOI: 10.1002/bio.4879

Yan Wang, Peng Liu, Jianzhong Zhang, Shuangshuang Wen

引用次数: 0