Perfusion-Uk最新文献

{"title":"Heartmate 3 left ventricular assist device system in patients with glucose-6-phosphate dehydrogenase deficiency.","authors":"Elena Grasso, Roberto Lorusso, Ahmed Ibrahim, Mohamad Ibrahem Abdelhamed, Hassane Abdallah, Omer Ali Sayin","doi":"10.1177/02676591251334897","DOIUrl":"https://doi.org/10.1177/02676591251334897","url":null,"abstract":"<p><p>BackgroundGlucose-6-phosphate dehydrogenase (G6PD) deficiency is a genetic enzymatic disorder that affects millions of people worldwide and characterized by hemolysis under oxidative stress. Left ventricular assist devices (LVADs) have substantially enhanced survival and quality of life for individuals with advanced heart failure. However, their use is associated with the risk of hemolysis, thrombosis, and embolic events. These risks may be heightened in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Given the limited published research on this subject, the primary objective of this study was to assess the degree of hemolysis and identify associated factors in adult patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency who underwent Heartmate 3 (HM3) left ventricular assist device (LVAD) implantation.MethodsThis retrospective, observational, single-center study was conducted on adult (>18 years of age) patients with G6PD deficiency, who underwent LVAD implantation using the HM3 LVAD between 2017 and 2022. Hemolysis-related investigation and findings as well as in-hospital outcome were assessed.ResultsLeft ventricular assist devices (LVADs) were successfully implanted in five adult patients with G6PD deficiency, including one individual with associated sickle cell trait (SCT). There were no major complications or fatalities during the hospitalization period. The average follow-up duration was 30 months (mean 30.4 ± 13). During the follow-up period, two patients died, two LVADs were explanted, and one patient received a heart transplant. No instances of macroscopic hemolysis were observed throughout the follow-up period.ConclusionsWhile our study was limited in size, LVADs seem safe for G6PD-deficient patients and offer significant clinical benefits. Larger studies are needed to confirm this and assess long-term interactions.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251334897"},"PeriodicalIF":1.1,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144043249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cholesterol levels as a predictive marker for ICU survival in patients with cardiogenic shock supported by VenoArterial ExtraCorporeal membrane oxygenation.","authors":"Maarten de Haan, Etienne Bertjens, Herman G Kreeftenberg, Mohamed A Soliman-Hamad, Rick Bezemer, R Arthur Bouwman","doi":"10.1177/02676591251334896","DOIUrl":"https://doi.org/10.1177/02676591251334896","url":null,"abstract":"<p><p>BackgroundVeno-Arterial Extracorporeal Life Support (VA ECMO) is a critical intervention for patients with cardiogenic shock, serving as bridge to recovery, transplantation, or long-term therapies. The complexity of VA ECMO and its associated risks underscore the need for reliable prognostic markers to guide patient management. This study aimed to evaluate whether cholesterol levels could serve as a specific marker for ICU survival in patients with cardiogenic shock treated with VA ECMO.MethodsA retrospective observational study was conducted at Catharina Hospital Eindhoven, The Netherlands, between January 2013 and November 2019. Data from 67 patients treated with VA ECMO were analyzed. Cholesterol levels were measured daily from day 1 to day 5 after VA ECMO initiation. Demographic data, comorbidities, and outcomes were extracted from the patient data management system. Statistical analysis was performed, with a focus on non-normality of data distribution and the predictive value of cholesterol levels on ICU survival.ResultsThe study identified a significant association between higher cholesterol levels on the first day of VA ECMO treatment and increased ICU survival. A cholesterol threshold of 2.0 mmol/L was found to be an independent predictor of survival, with patients above this threshold having a higher survival rate. Multivariate logistic regression analysis confirmed the significance of this cholesterol threshold in predicting ICU survival.ConclusionCholesterol levels measured on the first day after the initiation of VA ECMO are a significant indicator of ICU survival in patients with cardiogenic shock. A threshold of 2.0 mmol/L is particularly predictive, offering a potential prognostic tool for clinicians managing these critically ill patients.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251334896"},"PeriodicalIF":1.1,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood products for paediatric patients in congenital heart surgery: A retrospective, single- centre study.","authors":"L Thumm, N Sikora","doi":"10.1177/02676591251334904","DOIUrl":"https://doi.org/10.1177/02676591251334904","url":null,"abstract":"<p><p>IntroductionBlood transfusions during paediatric cardiac surgery with (cardiopulmonary bypass) CPB carry increased risks, including infection and immunological complications. This study evaluates blood product use in the Clinic for Paediatric Cardiology and Cardiac Surgery at the Children's University Hospital following the implementation of a revised blood management protocol from 2020 to 2023.MethodsA retrospective review of 135 paediatric patients who underwent congenital cardiac surgery with CPB was conducted. Patients were categorized into three age groups: Group 1 (<1 year), Group 2 (1 - 4 years), and Group 3 (>4 years). Data on erythrocyte, fresh frozen plasma (FFP), cryoprecipitate, and platelet use were analysed using the Kruskal-Wallis and Spearman's rho tests, with significance set at <i>p</i> < .05, and confidence interval (CI) of 95% quoted when applicable.ResultsErythrocyte use significantly declined over 4 years, with the largest reductions observed from 2020 to 2023 [<i>p</i> < .0001]. Older and heavier patients required fewer transfusions, with a significant inverse correlation between weight and erythrocyte use [Spearman's rho = -0.29, <i>p</i> = .001]. Platelet use also decreased significantly from 2020 to 2023 [<i>p</i> = .04], while FFP and cryoprecipitate use declined notably over the same period [p < 0.01].ConclusionOver 4 years, significant reductions in blood product use were observed, particularly for erythrocytes and platelets. Patients' age and weight were inversely related to erythrocyte transfusion needs. These trends may reflect improvements in surgical techniques and blood management protocols, with potential benefits for patient outcomes.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251334904"},"PeriodicalIF":1.1,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A robust analysis of alternate methods for estimating blood volume.","authors":"Philip Cumpston","doi":"10.1177/02676591251328856","DOIUrl":"https://doi.org/10.1177/02676591251328856","url":null,"abstract":"<p><p>AimThis study evaluates the accuracy of a newly derived blood volume estimation formula based on the Boer equation for lean body mass, comparing its performance against the Nadler, Allen and Lemmens-Bernstein-Brodsky formulas.MethodsBlood volume estimation was evaluated using two datasets: the Retzlaff dataset, based on 78 healthy individuals, and the Allen dataset, derived from 81 subjects, two of European descent, the remainder Chinese 'medical, nursing and pedagogic students, technicians, clerks and family members' and one young Chinese physician. The formulas were compared using robust statistical methods, including the Wilcoxon Signed-Rank Test, permutation tests, Bland-Altman analysis, and Proportion Within Range.ResultsAcross all methods, the formula derived from the Boer equation showed the narrowest limits of agreement and smallest variability in most metrics, highlighting its potential as the most accurate and clinically useful tool for blood volume estimation. The Nadler formula also performed well but with slightly larger errors and bias.ConclusionThis study highlights the limitations of the Allen formula and demonstrates the superior performance of the Boer formula, which is derived from lean body mass. While the Allen formula performed well on its original dataset, it showed higher variability and less accuracy on more modern data. Both the Nadler and Boer formulas exhibited greater precision, with the Boer formula showing slightly lower variability. The study emphasizes the importance of using independent data sets for validation and addresses a critical gap in blood volume assessment by using robust techniques for analysis.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251328856"},"PeriodicalIF":1.1,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of drainage cannula type on patients' fluid balance in venovenous extracorporeal membrane oxygenation: A historical cohort study.","authors":"Sonny Thiara, Alexander Willms, George Isac, Gordon Finlayson, Hussein Kanji, Kali Romano, Cara Summers, Ryan Hoiland, Mypinder Sekhon, Donald Griesdale","doi":"10.1177/02676591251331163","DOIUrl":"https://doi.org/10.1177/02676591251331163","url":null,"abstract":"<p><p><i>Objective</i>: Positive fluid balance in patients on veno-venous extracorporeal membrane oxygenation (VV ECMO) is associated with increased mortality. Drainage insufficiency on VV ECMO is a common occurrence and managed with fluid administration. The use of multi-stage drainage cannulas may result in decreased drainage insufficiency, but it is unclear the effects this may have on patient fluid balance.<i>Design</i>: A historical cohort study was conducted on adult patients undergoing VV ECMO for acute respiratory failure in femoral-jugular configuration.<i>Setting</i>: Intensive Care Unit.<i>Patients</i>: Adult patients undergoing VV ECMO for acute respiratory failure.<i>Interventions</i>: Cumulative fluid balance in the first 7 days following initiation of VV ECMO was examined. The relationship between cumulative daily fluid balance over the first 7 days and type of drainage cannula was assessed using mixed methods linear regression.<i>Measurements and Main Results</i>: We included 82 consecutive patients between April 1st, 2020 and September 1st, 2022. 47 (57%) patients were treated with a single-stage drainage cannula. Our final model showed the use of a multi-stage cannula decreased fluid balance by 740 mL/day (95% CI: -1360 to -118, <i>p</i> = .02) compared to patients with a single-stage drainage cannula for the first 7 days.<i>Conclusions</i>: The use of multi-stage drainage cannulas resulted in improved fluid balance in patients on VV ECMO in the first 7 days.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251331163"},"PeriodicalIF":1.1,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left ventricular unloading and survival outcomes in pediatric acute fulminant myocarditis patients receiving extracorporeal membrane oxygenation: A systematic review and meta-analysis.","authors":"Hwa Jin Cho, Reverien Habimana, Insu Choi, Min-Keun Song, Ji-Hyuk Yang, Yoonseo Lee, Hoon Ko, Matteo Di Nardo, In Seok Jeong","doi":"10.1177/02676591251334895","DOIUrl":"https://doi.org/10.1177/02676591251334895","url":null,"abstract":"<p><p>BackgroundAcute fulminant myocarditis (AFM) is a severe condition in pediatric patients. Extracorporeal membrane oxygenation (ECMO) is often used as a supportive therapy, but survival rates and the impact of adjunctive therapies like left ventricular (LV) unloading and bridge-to-heart transplantation remain unclear. This meta-analysis evaluates survival outcomes in pediatric AFM patients treated with ECMO and assesses the influence of these strategies.MethodsThis systematic review and meta-analysis followed PRISMA guidelines. Databases, including PubMed, Embase, and the Cochrane Library, were searched for studies published in the last 10 years. Inclusion criteria were studies reporting survival rates of pediatric AFM patients treated with ECMO. Data were analyzed using fixed and random-effects models. Subgroup and univariable meta-regression analyses identified factors associated with survival.ResultsFrom 2308 articles, 10 studies met the inclusion criteria, totaling 210 pediatric patients. The pooled survival rate was 67% (95% CI: 37%-97%). Subgroup analyses showed higher survival in patients receiving LV unloading (82% vs 63%; <i>p</i> < .01) and those bridged to heart transplantation, though not statistically significant. Univariable meta-regression identified LV unloading as a significant predictor of survival (<i>p</i> = .02). Other factors, such as age, gender, and cardiac arrest before ECMO, showed no significant associations with survival. Cumulative meta-analysis indicated an improving trend in survival over the years.ConclusionsThis meta-analysis suggests an association between ECMO and improved survival in children with AFM. While LV unloading may offer benefits, the retrospective nature of the included studies, along with potential confounding factors, necessitates cautious interpretation. Further well-designed prospective studies are required to establish its optimal role, indications, and timing in pediatric ECMO patients with AFM.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251334895"},"PeriodicalIF":1.1,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Litigation associated with the use of extracorporeal membrane oxygenation.","authors":"Paul S Jansson, Antonio Coppolino, Mohamed Keshk, Amy Hackmann, Raghu R Seethala","doi":"10.1177/02676591251334899","DOIUrl":"https://doi.org/10.1177/02676591251334899","url":null,"abstract":"<p><p>IntroductionExtracorporeal membrane oxygenation (ECMO) is a high-risk treatment but the legal risk surrounding its use is unknown.MethodsRetrospective review of the Westlaw legal database was used to identify eligible cases. The reason for litigation (directly related to ECMO or not directly related to ECMO) and other case details were abstracted. Descriptive statistics were calculated.ResultsA total of 28 cases were identified, nine related to ECMO and 19 not related to ECMO. Eight cases were settled out of court, while seven had a plaintiff verdict and 13 had a defense verdict. The median payment to the plaintiff in cases related to ECMO was $1,704,500 (range: $400,000 to $100,395,901; IQR $436,500 to $27,318,225) and for cases not related to ECMO was $4,275,812 (range: $375,000 to $7,700,000; IQR $1,500,000 to $6,500,000). The most common reason for litigation in the ECMO-related group was for access to ECMO (failure to transfer and delay or failure to offer ECMO) while the most common reason for litigation in the non-ECMO related group was perinatal complications. Virtually all patients (27 of 28) suffered permanent harm or death.ConclusionsAlthough a high-risk technology, cases alleging harm attributable to ECMO were rare (2 of 28) and both involved catastrophic technical errors. Failure or delay in offering ECMO was a more common reason for litigation. Settled and verdict damages were high, suggesting cases involving ECMO are at risk for litigation, although patients who require ECMO are by definition critically ill and are at high risk for poor outcomes, regardless of ECMO therapy.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251334899"},"PeriodicalIF":1.1,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of high-fidelity simulation on the performance of oxygenator change-outs among perfusion students.","authors":"Julie Collins, Alexis Voitik, Alexander R Leonor, Luke T Juricek, Makenna Ellis, Ramandeep Kaur, Allison Weinberg","doi":"10.1177/02676591251331159","DOIUrl":"https://doi.org/10.1177/02676591251331159","url":null,"abstract":"<p><p>BackgroundSimulation is increasingly utilized in the clinical training of healthcare professionals. Many perfusion programs in the United States use simulation to teach students both technical skills and effective communication. However, there is a lack of clarity regarding the optimal timing for introducing simulation into the curriculum and how to assess students' competencies. This study aims to evaluate whether combining simulation with didactic education is more effective than didactic education alone for learning perfusion-specific tasks, such as oxygenator changeouts.MethodsThis was a pilot, randomized controlled study conducted during November 2020. Subjects who were in their first year and enrolled in a cardiovascular perfusion program at the university were included. Subjects were randomly assigned to receive didactic education alone (control) or didactic in combination with the simulation training (experimental). Both groups received the didactic portion of the oxygenator change out procedure and the experimental group received supplemental simulation training. The primary outcome was oxygenator change-out completion time (recorded in minutes and seconds) to identify and change-out an oxygenator in a cardiopulmonary bypass circuit. The secondary outcome was total communication score and subject's overall performance assessment using the scoring system referenced by Burkhart et al.ResultsThe experimental group (<i>n</i> = 8) performed the oxygenator change-out significantly faster (363.63 ± 87.1 seconds vs 558.11 ± 185.75 seconds, <i>p</i> = .016) as compared to the control group (<i>n</i> = 9). However, there was no significant difference between the control and experimental groups in overall communication skills (<i>p</i> = .152) or the scoring system (<i>p</i> = .053) used to score subjects technical skills.ConclusionThe study findings revealed that the group receiving both didactic instruction and simulation performed an oxygenator change-out significantly faster than the group that received only didactic instruction. These results suggest that incorporating simulation of emergency scenarios into perfusion training can enhance students' speed in performing complex tasks, better preparing them for real clinical situations.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251331159"},"PeriodicalIF":1.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Redefining ECMO cannulation: A case for TEE-guided VP ECMO and flotation catheter.","authors":"Daniel Manzur-Sandoval, Gian Manuel Jiménez-Rodríguez, Eduardo Bucio-Reta, Alejandro Sierra-González de Cossío, Jessy Steve Masso-Bueso, Gustavo Rojas-Velasco","doi":"10.1177/02676591251331017","DOIUrl":"https://doi.org/10.1177/02676591251331017","url":null,"abstract":"<p><p>Venopulmonary ECMO (VP ECMO) is an advanced support strategy for patients with severe respiratory failure and right ventricular (RV) dysfunction, providing pulmonary protection by oxygenating blood and unloading the RV. This case discusses a 57-year-old female with septic cardiomyopathy, refractory cardiogenic shock, and ARDS, who developed progressive respiratory deterioration despite conventional treatment. Due to patient instability, she was placed on VP ECMO (femoral venous drainage and pulmonary artery reinfusion), guided exclusively by transesophageal echocardiography (TEE). The use of TEE enabled successful pulmonary artery cannulation without the need for fluoroscopic guidance. Additionally, a flotation catheter was used to facilitate guidewire placement, improving procedural success in this emergent situation. After initiating ECMO, the patient showed significant clinical improvement, with resolution of RV dilation and paradoxical septal motion. This case underscores the feasibility and safety of TEE-guided VP ECMO, suggesting that the flotation catheter technique could be beneficial in critical situations, warranting further investigation to establish clinical guidelines.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251331017"},"PeriodicalIF":1.1,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143774625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of red blood cell transfusions and hemostatic transfusions and their relation to thromboses in pediatric patients receiving extracorporeal membrane oxygenation therapy.","authors":"Michael J Martinez, Tahmineh Romero, Myke D Federman","doi":"10.1177/02676591241260185","DOIUrl":"10.1177/02676591241260185","url":null,"abstract":"<p><p>ObjectiveTo evaluate the association of RBC transfusions with thrombosis in pediatric patients on extracorporeal membrane oxygenation (ECMO) and compare this with the transfusion of other blood products and their association with thrombosis.MethodsThis was a secondary analysis of the Bleeding and Thrombosis during ECMO (BATE) study, which was a multicenter prospective observational study involving patients less than 19 years of age treated with ECMO.Results514 patients were analyzed, of which 282 (55%) were neonates (≤31 days) and 302 (58.7%) were male. When analyzing the entire cohort independently of other blood products, each 10 mL/kg of packed red blood cells (PRBCs) was associated with a 1.0% increase in the average number of thromboses (1.010; 1.008,1.013; <i>p</i> < .001). In neonates, each 10 mL/kg of PRBC was associated with a 0.9% increase in the average number of thromboses (1.009; 1.003,1.013; <i>p</i> < .001). In pediatric patients, each 10 mL/kg of PRBC was associated with a 1.2% increase in the average number of thromboses (1.012; 1.008,1.012; <i>p</i> < .001). The percent increase in the average number of thromboses was similar between PRBCs, platelets, and FFP, but increased significantly with cryoprecipitate.ConclusionsRBC transfusions and hemostatic transfusions are likely associated with thromboses in pediatric patients on ECMO.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"750-756"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141293903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}