Perfusion-UkPub Date : 2025-04-01Epub Date: 2024-05-13DOI: 10.1177/02676591241249325
{"title":"Corrigendum to \"Perfusion education and training in Europe anno 2023\".","authors":"","doi":"10.1177/02676591241249325","DOIUrl":"10.1177/02676591241249325","url":null,"abstract":"","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"799-800"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-04-01Epub Date: 2024-06-03DOI: 10.1177/02676591241259140
Ibrahim Antoun, Majed Aljabal, Alkassem Alkhayer, Yaman Mahfoud, Alamer Alkhayer, Peter Simon, Ahmed Kotb, Joseph Barker, Akash Mavilakandy, Muhammad Usman Naseer, Riyaz Somani, G André Ng, Mustafa Zakkar
{"title":"Atrial fibrillation inpatient management patterns and clinical outcomes during the conflict in Syria: An observational cohort study.","authors":"Ibrahim Antoun, Majed Aljabal, Alkassem Alkhayer, Yaman Mahfoud, Alamer Alkhayer, Peter Simon, Ahmed Kotb, Joseph Barker, Akash Mavilakandy, Muhammad Usman Naseer, Riyaz Somani, G André Ng, Mustafa Zakkar","doi":"10.1177/02676591241259140","DOIUrl":"10.1177/02676591241259140","url":null,"abstract":"<p><p>BackgroundAtrial fibrillation (AF) is the most common sustained arrhythmia worldwide. However, there is no data on AF inpatient management strategies and clinical outcomes in Syria.ObjectivesThe study aims were to review the inpatient management of patients with AF and assess cardiovascular (CV) mortality in a tertiary cardiology centre in Latakia, Syria.MethodsA single-centre retrospective observational cohort study was conducted at Tishreen's University Hospital, Latakia, Syria, from June 2021 to June 2023. Patients ≥16 years of age presenting and being treated for AF as the primary diagnosis with or without a thromboembolic event were included. Medical records were examined for patients' demographics, laboratory results, treatment plans and inpatient details. Studied outcomes include inpatient all-cause and CV mortality, ischemic and bleeding events, and conversion to sinus rhythm (SR).ResultsThe study included 596 patients. The median age was 58, and 61% were males. 121 patients (20.3%) were known to have AF. A rhythm control strategy was pursued in 39% of patients. Ischemic and bleeding events occurred in 62 (11%) and 12 (2%), respectively. CV and all-cause mortality occurred in 28 (4.7%) and 31 patients (5%), respectively. The presence of valvular heart disease (VHD) (adjusted odds ratio (aOR) = 9.1, 95% confidence interval (CI): 1.7 to 55.1, <i>p</i> < .001), thyroid disease (aOR: 9.7, 95% CI = 1.2 to 91.6, <i>p</i> < .001) and chronic obstructive pulmonary disease (COPD) (aOR: 82, 95% CI: 12.7 to 71, <i>p</i> < .001) were independent risk factors of increased CV inpatient mortality.ConclusionSyrian inpatients admitted with AF in Latakia are relatively younger than those in other countries. Active thyroid disease, COPD and VHD were independent risk factors of inpatient CV mortality with AF.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"711-719"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141236194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-03-28DOI: 10.1177/02676591251331158
Yota Suzuki, Ravi Radhakrishnan, Rui-Min D Mao, John Ryan, Alexander Wisniewski, Philip Carrott, Ernest G Chan, William Lynch, Gabriel Loor, Subhasis Chatterjee, Masashi Furukawa, Pablo G Sanchez
{"title":"Extracorporeal membrane oxygenation after lung transplant: An ELSO registry analysis.","authors":"Yota Suzuki, Ravi Radhakrishnan, Rui-Min D Mao, John Ryan, Alexander Wisniewski, Philip Carrott, Ernest G Chan, William Lynch, Gabriel Loor, Subhasis Chatterjee, Masashi Furukawa, Pablo G Sanchez","doi":"10.1177/02676591251331158","DOIUrl":"https://doi.org/10.1177/02676591251331158","url":null,"abstract":"<p><p>BackgroundThe use of extracorporeal membrane oxygenation (ECMO) has expanded and is now widely applied to perioperative care in lung transplant. Respiratory failure after lung transplant is a clinical challenge where ECMO plays a critical role.MethodsThe Extracorporeal Life Support Organization registry was queried for patients 18 years and older who were treated with ECMO after lung transplant in 2010-2022. ECMO runs for more than 24 hours after lung transplant were included regardless of the timing of initiation. Univariable analyses were performed to compare procedural and patient characteristics across ECMO eras. Multivariable logistic regression was performed to identify predictors of surviving to discharge.ResultsOne-thousand nine-hundred and sixty-six patients met the inclusion criteria, and 1422 patients (72.3%) survived to discharge. The number of ECMO runs steadily increased throughout the study period, with a trend of improving survival. Higher annual center volume (Odds Ratio[OR]: 0.97, <i>p</i> < 0.001), longer ECMO duration (OR 1.01/day, <i>p</i> < 0.001), veno-arterial mode (OR 2.28, <i>p</i> < 0.001), initiation of ECMO >72 hours after transplant (OR 3.93, <i>p</i> < 0.001), and ventilator duration >5 days (1.55, <i>p</i> = 0.035) were associated with higher probability of survival to discharge.ConclusionsECMO after lung transplant has expanded over the last 12 years along with improved survival. The data suggest a potential benefit of early ECMO initiation in this patient population. High ECMO volume was associated with better outcomes, and expertise in ECMO is considered essential in lung transplant centers.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251331158"},"PeriodicalIF":1.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-03-25DOI: 10.1177/02676591251328926
Luis Eduardo Silva Delgado, Erika Thalia Vasquez Cueva, Katherine Silva Delgado, Jorge Luis Maguiña Quispe, Eduardo Silva
{"title":"Long-term outcomes after pediatric cardiac surgery: A 20-year single-institution study.","authors":"Luis Eduardo Silva Delgado, Erika Thalia Vasquez Cueva, Katherine Silva Delgado, Jorge Luis Maguiña Quispe, Eduardo Silva","doi":"10.1177/02676591251328926","DOIUrl":"https://doi.org/10.1177/02676591251328926","url":null,"abstract":"<p><p>PurposeThis study evaluated the long-term outcomes and factors associated with survival in patients undergoing cardiac surgery with cardiopulmonary bypass at a children's cardiac center.MethodsA retrospective cohort study was conducted between 2001 and 2020 Outcomes included early or late survival and associated risk factors for survival.ResultsSurvival had a mean of 16.78 years (95% CI 16.50-17.06). The survival rates at 1, 5, 10, and 19 years were 91, 88, and 88%, respectively. Cox regression analysis indicated that age HR = 0.39, 95% CI [0.26-0.59], the RACHS-1 scale HR = 9.92, 95% CI [3.67-26.79], open chest HR = 1, 90, 95% CI [1.20-3.00], cardiac arrest HR = 3.91, 95% CI [2.40-6.36] and peritoneal dialysis HR = 6.71, 95% CI [4, 33-10.38], were independently associated with worse survival.Conclusionslong-term survival of children who undergo cardiac surgery at our single center was satisfactory. Age, higher RACHS score, delayed sternal closure, cardiac arrest, and peritoneal dialysis were strong predictors of adverse outcomes affecting early and long-term survival of pediatric cardiac surgery.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251328926"},"PeriodicalIF":1.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143701961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-03-23DOI: 10.1177/02676591251329549
Hinpetch Daungsupawong, Viroj Wiwanitkit
{"title":"Level of sedation in patients with COVID-19 supported with ECMO: Comment.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.1177/02676591251329549","DOIUrl":"https://doi.org/10.1177/02676591251329549","url":null,"abstract":"","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251329549"},"PeriodicalIF":1.1,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-03-02DOI: 10.1177/02676591251319684
Olivia Liu, Philip Y Sun, Syed A Ahmad, Andrew Kalra, Amy Feng, Glenn J R Whitman, Bo Soo Kim, Sung-Min Cho
{"title":"Characteristics and risk factors of delirium in patients on veno-arterial extracorporeal membrane oxygenation.","authors":"Olivia Liu, Philip Y Sun, Syed A Ahmad, Andrew Kalra, Amy Feng, Glenn J R Whitman, Bo Soo Kim, Sung-Min Cho","doi":"10.1177/02676591251319684","DOIUrl":"https://doi.org/10.1177/02676591251319684","url":null,"abstract":"<p><strong>Purpose: </strong>Sparse data exist on delirium in VA-ECMO. We aim to describe the characteristics, risk factors, and outcomes of delirium in VA-ECMO.</p><p><strong>Methods: </strong>We retrospectively reviewed adults's electronic medical records on VA-ECMO in our ECMO registry in 2016-2022. Delirium was assessed by the Confusion Assessment Method for the intensive care unit when patients scored -3 or above on the Richmond Agitation-Sedation Scale. The primary outcomes were delirium prevalence and the proportion of delirium-present days while on VA-ECMO support. Multivariable logistic regression was used to evaluate delirium risk factors.</p><p><strong>Results: </strong>Of 208 patients (median [interquartile range] age: 53 [40-62]), 138 (66.3%) had delirium during ECMO. Delirium occurred on day 2.5 [1.0-7.0] of ECMO and was detected in 42% [20%-66%] of ECMO days. There were no differences in acute brain injury (24% vs 33%, <i>p</i> = .34) between patients with and without delirium. Survival analysis showed no significant association between delirium and 30-day mortality (<i>p</i> = .24). In multivariable analysis, ECMO day 1 arterial carbon dioxide partial pressure (adjusted odds ratio [aOR] = 1.29; 95% CI = 1.03-1.73), number of sedatives (aOR = 2.67; 95% CI = 1.68-2.95), and African American race/ethnicity (aOR = 16.45; 95% CI = 9.65-22.51) were associated with delirium.</p><p><strong>Conclusions: </strong>Delirium was present in 66.3% of VA-ECMO patients and was detected early during ECMO. Modifiable risk factors included multiple sedative agents and early hypercapnia. Delirium did not increase risk for mortality.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251319684"},"PeriodicalIF":1.1,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-03-02DOI: 10.1177/02676591251320851
Rajesh Kasimahanti, K Venkateswara Rao, Dodda Sai Ramadevi, Mallela Balaji, Atchyutha Rao Gongada
{"title":"Modifying veno - venous extra corporeal membrane oxygenation management for situs inversus totalis - A case report.","authors":"Rajesh Kasimahanti, K Venkateswara Rao, Dodda Sai Ramadevi, Mallela Balaji, Atchyutha Rao Gongada","doi":"10.1177/02676591251320851","DOIUrl":"https://doi.org/10.1177/02676591251320851","url":null,"abstract":"<p><p><i>Introduction</i>Situs inversus totalis is a rare condition affecting 1 in 10,000 individuals, in which the heart and abdominal organs are reversed. This mirrored arrangement of the great vessels presents unique challenges for vascular access during extracorporeal membrane oxygenation (ECMO).<i>Case Report</i>A 41-year-old male presented with a fever, cough, and shortness of breath. Initial chest radiography revealed bilateral infiltrates (right more than left) and dextrocardia, while computed tomography of the chest and abdomen confirmed situs inversus totalis. The patient required venovenous ECMO for refractory hypoxemia. The ECMO setup was modified with an access cannula placed in the left femoral vein and a return cannula inserted into the left internal jugular vein. Bronchoscopy performed for lung collapse revealed a bilobed right lung and trilobed left lung. After clinical improvement, ECMO support was weaned off after 9 days, and the patient was discharged after 28 days.<i>Conclusion</i>Modifying the ECMO setup and adjusting management strategies are crucial for treating refractory hypoxemia in patients with situs inversus.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251320851"},"PeriodicalIF":1.1,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-03-01Epub Date: 2024-03-14DOI: 10.1177/02676591241240036
Francesco Gaiani, Marco Giani, Beatrice Vergnano, Jeff Sardella, Fabrizio Cappellini, Marco Casati, Matteo Pozzi, Giuseppe Foti
{"title":"Extracorporeal cardio-pulmonary resuscitation in a patient with missed diagnosis of sodium nitrite intoxication.","authors":"Francesco Gaiani, Marco Giani, Beatrice Vergnano, Jeff Sardella, Fabrizio Cappellini, Marco Casati, Matteo Pozzi, Giuseppe Foti","doi":"10.1177/02676591241240036","DOIUrl":"10.1177/02676591241240036","url":null,"abstract":"<p><strong>Introduction: </strong>Critical poisoning with sodium nitrite (NaNO<sub>2</sub>) can present challenges in promptly identifying and managing acute methemoglobinemia.</p><p><strong>Case report: </strong>We report the case of an overt self-intoxication by an initially unknown agent, leading to cardiac arrest. Despite prodromal signs of cyanosis, coma, desaturation, and hypotension, methemoglobinemia went unrecognized during extracorporeal cardiopulmonary resuscitation (ECPR) as the point-of-care test failed to provide methemoglobin levels, leading to untreated methemoglobinemia. The blood flowing through the oxygenator notably maintained the same brown colour. Return of spontaneous circulation was never achieved, and the patient was declared dead after 60 min of unsuccessful resuscitation. Cause of death by means of NaNO<sub>2</sub> voluntary ingestion was later clarified and confirmed by postmortem finding of elevated nitrite and nitrate concentration.</p><p><strong>Conclusions: </strong>This case highlights the risk of failure of ECPR in the context of cardiac arrest due to methemoglobinemia, emphasizing the critical need for prompt recognition of the causative agent and early administration of antidotes.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"519-522"},"PeriodicalIF":1.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140133101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-03-01Epub Date: 2024-03-12DOI: 10.1177/02676591241238865
Noritsugu Naito, Hisato Takagi
{"title":"Meta-analysis of central and peripheral cannulation for type A aortic dissection.","authors":"Noritsugu Naito, Hisato Takagi","doi":"10.1177/02676591241238865","DOIUrl":"10.1177/02676591241238865","url":null,"abstract":"<p><strong>Background: </strong>Acute type A aortic dissection necessitates rapid and effective arterial cannulation techniques for optimal outcomes. This meta-analysis compares the safety and effectiveness of direct aortic cannulation (AoC) with peripheral cannulation (PC) via the femoral or axillary arteries in aortic surgery for acute type A aortic dissection.</p><p><strong>Methods: </strong>A systematic review following PRISMA guidelines identified 10 retrospective studies encompassing 2518 patients (961 AoC, 1557 PC). Pooled odds ratios (OR) with 95% confidence intervals (CI) were calculated to analyze perioperative characteristics, short-term mortality rates, and postoperative complications including stroke and acute kidney injury.</p><p><strong>Results: </strong>Short-term mortality did not significantly differ between AoC and PC (OR [95% CI] = 0.78 [0.61-1.01], <i>p</i> = .06). Likewise, postoperative stroke (OR [95% CI] = 0.86 [0.63-1.17], <i>p</i> = .33) nor acute kidney injury (OR [95% CI] = 1.11 [0.89-1.37], <i>p</i> = .35) showed no significant differences. AoC exhibited shorter operation time whereas there were no significant differences in aortic cross clamp time and cardiopulmonary bypass time between both groups. Our meta-regression analysis, considering the distal extent of aortic replacement, indicated that variations in aortic replacement rates did not significantly impact the observed outcomes.</p><p><strong>Conclusion: </strong>AoC is a viable alternative to PC for acute type A aortic dissection. While both approaches offer comparable outcomes, AoC's advantage in shorter operation time warrants thoughtful consideration in clinical practice.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"417-430"},"PeriodicalIF":1.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140111968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}