Perfusion-Uk最新文献

{"title":"Successful combined liver-kidney transplant with intraoperative VA-ECMO and Impella 5.5 support.","authors":"Mehran Rahimi, Sarah Madira, Takuya Wada, Jessica Lindemann, Shreya Goswami, Mary Sullivan, Kunal D Kotkar, Muhammad F Masood, Marc A Sintek, Justin Vader, Ivan Kangrga, Jennifer Yu, William C Chapman, Amit A Pawale","doi":"10.1177/02676591251372488","DOIUrl":"https://doi.org/10.1177/02676591251372488","url":null,"abstract":"<p><p><i>Introduction:</i> Cardiogenic shock during liver transplantation (LT) is a significant challenge, particularly in patients with comorbidities like end-stage renal disease (ESRD). Mechanical circulatory support (MCS), including veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used to manage refractory shock in these complex cases. <i>Case Report:</i> This case report discusses the management of a 69-year-old patient who developed intraoperative refractory cardiogenic shock while undergoing combined liver-kidney transplantation and was supported with VA-ECMO and Impella 5.5 support. The simultaneous use of VA-ECMO and Impella, or \"ECPELLA,\" helped stabilize the hemodynamics, reverse the shock, enabling a successful KT, and subsequent left ventricular recovery. <i>Conclusion:</i> This case highlights the importance of interdisciplinary collaboration and careful hemodynamic management in complex transplants.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251372488"},"PeriodicalIF":1.1,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary on manuscript entitled \"Association of vasoactive active-inotropic score and poor outcomes in patients who underwent coronary artery bypass grafting: Systematic review and meta-analysis\" in press <i>Perfusion</i>.","authors":"Jackeline Flores, Kenneth Nugent","doi":"10.1177/02676591251372494","DOIUrl":"https://doi.org/10.1177/02676591251372494","url":null,"abstract":"","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251372494"},"PeriodicalIF":1.1,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of acute normovolemic hemodilution and retrograde autologous priming in reducing intraoperative packed red blood cell transfusion needs in coronary artery bypass surgery: A randomized controlled trial.","authors":"Cindy Elfira Boom, Riza Cintyandy, Hery Widodo, Ayudhia Putri, Muhamad Randy Givano, I Made Adi Parmana","doi":"10.1177/02676591251372497","DOIUrl":"https://doi.org/10.1177/02676591251372497","url":null,"abstract":"<p><p>BackgroundAcute normovolemic hemodilution (ANH) and retrograde autologous priming (RAP) are blood conservation techniques designed to reduce transfusion requirements.PurposeThis study evaluated the impact of combining ANH and RAP compared to RAP alone on intraoperative packed red blood cell (PRBC) transfusion and postoperative outcomes in coronary artery bypass grafting (CABG) surgery.Research designA single-center randomized controlled trial.Study sample72 patients scheduled for CABG surgery from July 2024 to December 2024 at the National Cardiovascular Center Harapan Kita in Indonesia. Patients were randomly assigned to ANH + RAP group (<i>n</i> = 36) and RAP group (<i>n</i> = 36).Data analysisMultivariate analysis assessed factors influencing final hemoglobin levels and intraoperative PRBC transfusion needs.ResultsThe ANH + RAP group experienced a significant reduction in the transfusion rate (19.4% vs 47.2%, <i>p</i> = 0.024) and the intraoperative allogeneic packed red blood cell units (0.2 ± 0.4 vs 0.5 ± 0.6, <i>p</i> = 0.012). The optimal ANH volume reduces intraoperative allogeneic PRBC transfusion was 380 mL (ROC area 0.862, 95% CI 0.703-1.000, <i>p</i> = 0.003). Single RAP procedure approaches were less effective when compared to the combination procedure for achieving higher final hemoglobin levels (β = -0.824, 95% CI -1.314 to -0.334, <i>p</i> = 0.001) and reducing the likelihood of intraoperative allogeneic PRBC transfusion (OR = 13.370, 95% CI 2.206 to 81.026, <i>p</i> = 0.005). Postoperative outcomes did not differ between groups.ConclusionThe combined use of ANH and RAP significantly reduces intraoperative allogeneic PRBC needs compared to RAP alone without affecting postoperative outcomes.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251372497"},"PeriodicalIF":1.1,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large-scale computed tomography study of aortic arch and supra-aortic artery morphology: Variations and potential implications for arterial extracorporeal life support access.","authors":"Jan Coveliers, Paolo Meani, Eliza Huizinga, Karthik Gutta, Giulia Piccirillo, Emanuele Gasparotti, Emanuele Vignali, Marilena Mazzoli, Mariusz Kowalewski, Wouter Huberts, Hamed Moradi, Michele Di Mauro, Robert J Holtackers, Monique de Jong, Sandro Gelsomino, Domenico Paparella, Simona Celi, Dorela Haxhiademi, Erik Körver, Arne Doddema, Michal J Kawczynski, Samuel Heuts, Elham Bidar, Roberto Lorusso","doi":"10.1177/02676591251370074","DOIUrl":"https://doi.org/10.1177/02676591251370074","url":null,"abstract":"<p><p>BackgroundThe anatomy and morphology of the aortic arch and its supra-aortic arteries can vary significantly among individual patients. This variability may have a particular relevance in cardiovascular procedures or interventions, and specifically during the use of mechanical circulatory support. This importance accounts for a specific influence on hemodynamics in veno-arterial extracorporeal membrane oxygenation (V-A ECMO) through an axillary/subclavian artery access. The related hemodynamic effects and interplay with native cardiac blood flow dynamics have been poorly investigated.MethodsTo assess the existing patterns of aortic arch and related supra-aortic artery morphology, thoracic computed tomography (CT) scans of patients undergoing pre-procedural (trans-catheter aortic valve or aortic or other cardiovascular surgery) assessment were investigated. All CT scans clearly showing the thoracic aorta in all its anatomical parts were selected and evaluated in terms of anatomical features (aortic arch type, position of the supra-aortic arteries along the aortic arch or ascending aorta, length and disposition of the ascendent aorta and aortic valve plane, and descending thoracic aorta). Aortic arch morphology was classified according to the Madhwal description,¹ namely Type I, II, and III based on the exit point of the left subclavian artery along the aortic arch, with Type III configuration with all the three supra-aortic arteries departing leftwards the aortic arch peak, and Type I presenting the left subclavian artery departing from the peak of the aortic arch.ResultsThe CT scans of 1228 patients were analyzed and categorized. Overall, 70% (860 cases) of the aortic arch were Type III, 16.9% (208 cases) Type II, and 8.4% (103 cases) Type I. No difference was found between male and female patients. Type III aortic arch morphology presents a potentially unfavorable relationship due to a retrograde flow from the right axillary or subclavian artery, in case of such a V-A ECMO perfusion access, allegedly towards/against the aortic valve and left ventricular ejection. Type I and II aortic arch morphology showed patterns potentially more favorable from a mechanistic point of view, with an apparent more favorable anatomical disposition for a blood flow mainly directed towards the descending aorta.ConclusionsAortic arch and supra-aortic artery morphology vary markedly among patients. However, in this large patient population, the majority of aortic arch morphology was Type III which has a potentially unfavorable interaction between the native blood flow and V-A ECMO retrograde flow from the right axillary/subclavian artery compared to the left-sided access. Dedicated fluid-dynamic studies investigating the actual right or left axillary artery-generated retrograde flow direction and distribution along the ascending aorta, aortic arch and descending aorta deserves further investigation. Indeed, the interplay of blood flows generated by th","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251370074"},"PeriodicalIF":1.1,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Calculation of blood loss in cardiac surgery: How should we monitor?","authors":"Yerlan Orazymbetov, Serik Aitaliyev, Povilas Jakuška, Audronė Veikutienė, Tadas Lenkutis, Rassul Zhumagaliyev, Aušra Saudargienė, Rimantas Benetis","doi":"10.1177/02676591251370110","DOIUrl":"https://doi.org/10.1177/02676591251370110","url":null,"abstract":"<p><p>BackgroundThe bleeding in cardiac surgery remains a significant clinical problem. There is no \"gold standard\" method to quantify blood loss. Traditional measurement of drainage volume often underestimates or overestimates, as it does not consider the type of fluid. We hypothesized that blood loss could be more accurately calculated using the Hb/kg index in terms of haemoglobin (Hb) mass loss per kilogram of the patient's body mass. This study aimed to ObjectiveTo develop a novel approach for calculating actual blood loss using the Hb/kg index.MethodsThis single-center prospective study included 195 patients who underwent cardiac surgery between October 2023 and November 2024. The Hb/kg index was calculated based on intraoperative Hb loss, Hb loss via chest tubes, packed red blood cell transfusions and patient weight. Eighty-six additional clinical predictors were analyzed using conventional statistics and machine learning algorithms. Predictors with statistically significant Spearman correlations were included for further analysis.ResultsLasso regression achieved the best overall performance in predicting Hb/kg index. It yielded the lowest mean squared error (0.08 ± 0.04), mean absolute percentage error (0.18 ± 0.10), with the highest correlation (0.92 ± 0.06) and R² score (0.82 ± 0.13). BMI showed a significant negative relationship (-0.018, <i>p</i> < 0.001). Postoperative Hb and haematocrit values had negative correlation (-0.69, <i>p</i> < 0.001 and -0.07, <i>p</i> < 0.015), while initial Hb was positively correlated (0.85, <i>p</i> < 0.001).ConclusionsThis method provides a more reliable and clinically relevant tool to calculate actual blood loss and allows for a more precise assessment and treatment.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251370110"},"PeriodicalIF":1.1,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delirium after coronary artery bypass grafting with cardiopulmonary bypass surgery: The value of cerebral autoregulation.","authors":"Greta Kasputytė, Birutė Kumpaitienė, Milda Švagždienė, Judita Andrejaitiene, Edmundas Širvinskas, Yasin Hamarat, Edvinas Chaleckas, Vilma Putnynaitė, Laimonas Bartusis, Rolandas Žakelis, Vytautas Petkus, Arminas Ragauskas, Tadas Lenkutis, Rimantas Benetis","doi":"10.1177/02676591251370076","DOIUrl":"https://doi.org/10.1177/02676591251370076","url":null,"abstract":"<p><p>IntroductionPostoperative delirium affects up to 60% of cardiac surgical patients. No reliable gold standard method exists for preventing delirium after cardiac surgery. An example of patient-personal monitoring is cerebral autoregulation (CA). This study aims to highlight the personal monitoring of patients' cerebral autoregulation and to determine its relationship with postoperative delirium. Additionally, it seeks to test the hypothesis that the duration of CA impairment influences the onset of postoperative delirium.MethodsA prospective study was conducted in 2021-2023. After approval of the Ethics Committee and with the patient's written consent, 104 adult patients undergoing elective coronary artery bypass graft (CABG) with cardiopulmonary bypass (CPB) surgery were enrolled. To diagnose possible delirium, all patients underwent a Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) test. CA monitoring using transcranial Doppler was performed. CA status index - Mx was recorded.ResultsOur study found that 12.5% of patients were diagnosed with delirium after on-pump CABG surgery. The total duration of cerebral autoregulation impairment (TCAI) was longer in the delirium group, 4783.0 seconds versus 4204.5 seconds (<i>p</i> = .047), with a cut-off at 4380 s. Longer cardiopulmonary bypass (CPB) leads to prolonged CA impairment (<i>p</i> < .001). The mean arterial pressure (MAP) during CPB was 69.67 mmHg in the non-delirium group and 74.91 mmHg in the delirium group (<i>p</i> = .001), with a cutoff at 73.669 mmHg.ConclusionsCA impairment is crucial for delirium development after cardiac surgery. The duration of the TCAI event increases the risk of delirium.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251370076"},"PeriodicalIF":1.1,"publicationDate":"2025-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Staged systemic hyperkalemia and deep hypothermia for myocardial protection in mini-thoracotomy reintervention: Preserving patency in post-CABG patent grafts.","authors":"Manoj Sadasivan, Rajesh M Ramankutty, Jecco Ani Babu, Nisha Joseph Pattani, Sari Sankaran Lilli, Jose Sasidharan Lilli, Aiswarya Mohan","doi":"10.1177/02676591251367870","DOIUrl":"https://doi.org/10.1177/02676591251367870","url":null,"abstract":"<p><p>BackgroundTraditional cardioplegia strategies often fail in cases with patent coronary grafts due to continuous myocardial perfusion, this necessitates for alternate approaches such as systemic hyperkalemic cardiac arrest. During redo cardiac surgeries, a patent left internal mammary artery (LIMA) might prevent the heart from maintaining electrical cardiac arrest. Induced systemic hyperkalaemia is a novel approach to maintain cardiac electromechanical arrest.Case summaryWe report a case of 66 year-old male with a history of Post CABG for Triple vessel disease (TVD) who required mini-thoractomy for left atrial myxoma excision. Given the existence of patent coronary grafts, attaining cardiac arrest with standard cardioplegia was not possible, necessitating the use of systemic hyperkalaemia for myocardial arrest. The patient was placed on Femoro-femoral cardiopulmonary bypass (CPB) and cooled to 20°C. To induce myocardial arrest, multiple potassium boluses were delivered, totalling 120 mEq/L potassium chloride (KCl) over multiple stages. Despite high potassium levels (6.7 mEq/L in the third arterial blood gas), CPB was successfully weaned off, and the surgical recuperation went smoothly. This case highlights the complexities of myocardial protection in redo cardiac surgery and underscores the role of systemic hyperkalaemia, perfusion management, ultrafiltration, and careful electrolyte management in such high-risk settings. To the best of our knowledge this is the first documented case report of its kind internationally. While there are previous reports of left atrial myxoma excision in post-CABG patients, including those managed using ventricular fibrillation, this is the first reported case in which systemic hyperkalemia combined with deep hypothermia was successfully utilized via a mini-thoracotomy approach in a post-CABG patient with a patent LIMA graft, without the use of aortic cross-clamping or ventricular fibrillation.ConclusionThis case shows the complexities of myocardial protection in redo cardiac surgeries with patent grafts. The use of systemic hyperkalemia is a viable but challenging alternative to cardioplegia, requiring meticulous potassium management and close hemodynamic monitoring.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251367870"},"PeriodicalIF":1.1,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endobronchial valves for severe air leak in critically ill children with necrotizing pneumonia requiring extracorporeal membrane oxygenation.","authors":"Alex J Katz, Bhavesh M Patel, Vanessa M Mazandi, Lauren M C Grant, Aoife Corcoran, Pelton Phinizy, Antoinette Wannes Daou, Garrett Keim, Paula M Magee, Myron Allukian, Todd J Kilbaugh, Sin Tran, Adam S Himebauch, Joseph Piccione, Kumaran Senthil","doi":"10.1177/02676591251365419","DOIUrl":"https://doi.org/10.1177/02676591251365419","url":null,"abstract":"<p><p>IntroductionAir leak is a common complication of necrotizing pneumonia in critically ill children. Severe air leaks impact effective oxygenation and ventilation, oftentimes necessitating multiple thoracostomy tubes and extracorporeal support. Endobronchial valves (EBV) are a minimally invasive intervention to control air leak that may expedite de-escalation of care for critically ill children with necrotizing pneumonia.MethodsA retrospective case series was conducted on patients at the Children's Hospital of Philadelphia who were hospitalized in the pediatric intensive care unit, required extracorporeal membrane oxygenation (ECMO), and underwent placement of one or more EBVs for air leak from July 2023 through August 2024.ResultsSix patients, median age 12 years (range 18 months to 18 years), were hospitalized for necrotizing pneumonia complicated by severe air leak and required ECMO. The most common etiology was a viral infection with bacterial co-infection. The median number of EBVs placed per patient was five. The median total time on ECMO was 10 days, with a median duration of 3.5 days after valve placement. The median duration of antibiotic therapy was 47 days (range 24 to 126 days). One patient had a contralateral pneumothorax after valve placement, and another died due to progression of multiorgan failure that began before EBV placement. The five surviving patients were discharged from the hospital, weaned from all respiratory support, and their valves were removed without complication.ConclusionEndobronchial valves are a feasible intervention for severe air leak in critically ill children with necrotizing pneumonia and may expedite liberation from ECMO.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251365419"},"PeriodicalIF":1.1,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prone positioning and bleeding risk during extracorporeal membrane oxygenation in severe ARDS patients.","authors":"Alessio Caccioppola, Francesco Padovano, Vittorio Scaravilli, Fabiana Madotto, Cristina Dulama, Alfredo Lissoni, Mauro Panigada, Giacomo Grasselli","doi":"10.1177/02676591251344861","DOIUrl":"https://doi.org/10.1177/02676591251344861","url":null,"abstract":"<p><p>PurposeTo assess whether prone positioning (PP) increases bleeding risk compared to supine positioning in ARDS patients undergoing veno venous Extracorporeal Membrane Oxygenation (VV ECMO).Materials and MethodsA single-center retrospective observational study was conducted between January 2012 and March 2023. Data were systematically collected from an institutional ECMO registry, including baseline characteristics, daily variables, bleeding events, and outcomes. We compared the relative risk (RR) and incidence rate ratio (IRR) of bleeding between 'Prone' and 'Supine' patients. Bleeding-free days were analyzed using Kaplan-Meier curves and the Log-Rank test.ResultsWe included 136 consecutive severe ARDS patients undergoing VV ECMO (65% male, age 52 ± 11, 53% bacterial pneumonia), with 85 (62%) and 51 (38%) in the 'Prone' and 'Supine' group respectively. Bleeding occurred in 79 (58%) patients, with 43 of these being major bleeding events, including 14 intracranial hemorrhages. Fifty-two (61%) 'Prone' patients versus 27 (53%) 'Supine' patients had bleeding (RR 1.11 (95% CI: 0.81-1.52), <i>p</i> = .44; IRR 1.08 (95% CI: 0.68-1.75), <i>p</i> = .75), with a tendency towards lower major bleeding incidence in the 'Prone' versus 'Supine' patients (IRR 0.54 (95% CI: 0.29-1.03), <i>p</i> = .06). Kaplan-Meier survival analysis showed no significant difference in bleeding-free days between the 'Prone' and 'Supine' groups (<i>p</i> = .11).ConclusionsPP during VV ECMO for ARDS was not associated with an increased incidence of bleeding. Further prospective studies are warranted to confirm these findings.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251344861"},"PeriodicalIF":1.1,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-fidelity extracorporeal membrane oxygenation simulation in medical training: A review and opportunities for the future.","authors":"Nicole M Thomasian, Wenting Ma, Sagar R Navare, Natalia I Girardi, Berhane M Worku, Ankur Srivastava, Liang Shen","doi":"10.1177/02676591251363773","DOIUrl":"https://doi.org/10.1177/02676591251363773","url":null,"abstract":"<p><p><b>Background:</b> The growing popularity of extracorporeal membrane oxygenation (ECMO) necessitates adequate education and training of the multidisciplinary teams caring for these medically complex patients. Simulation-based education (SBE) has been used in medical education for decades and has demonstrated effectiveness for teaching both procedural competency and teamwork-related skills. The continued wider adoption of SBE within medical training and the development of newer digital technologies have also seen SBE being increasingly adapted for ECMO education. <b>Purpose:</b> To qualitatively review the state of published knowledge on simulation-based ECMO education and training. <b>Research Design:</b> A literature search of electronic databases was conducted using Medical Subject Headings (MeSH) terms \"Extracorporeal Membrane Oxygenation\", \"Simulation Training\", \"High-Fidelity Simulation Training\", and \"Patient Simulation\", as well as relevant synonyms and keywords. Studies meeting inclusion criteria were analyzed, with information extracted regarding study characteristics and key findings. Major themes were identified and compiled into a narrative review. <b>Results:</b> A total of 38 articles published from 2006 to 2023 met criteria for inclusion for review. The literature reveals significant heterogeneity in the use of simulation-based ECMO curricula across medical specialties and institutions. A wide array of ECMO simulators and equipment are commercially available or have been described, with numerous small studies describing individual ECMO simulation training programs with substantial differences in practices. More recently, ECMO procedural skills training has utilized augmented reality, which may be a promising modality for future training. <b>Conclusions:</b> The literature regarding simulation-based ECMO education is heterogenous, but available studies suggest this modality of education can improve procedural skills, increase efficiency and familiarity with equipment, reduce procedural errors, practice team-based communication skills, and increased learner confidence. As the use of ECMO simulation expands, efforts should focus on the identification of high-fidelity simulators for specific purposes, developing standardized training regimens, and emphasizing team-based dynamics.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251363773"},"PeriodicalIF":1.1,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}