Perfusion-Uk最新文献

If you can't have fun doing what you are doing, you shouldn't be doing it.

IF 1.1 4区医学

Perfusion-Uk Pub Date : 2025-03-18 DOI: 10.1177/02676591251328614

John M Toomasian

引用次数: 0

Characteristics and risk factors of delirium in patients on veno-arterial extracorporeal membrane oxygenation. 静脉-动脉体外膜氧合患者谵妄的特征和风险因素。

IF 1.1 4区医学

Perfusion-Uk Pub Date : 2025-03-02 DOI: 10.1177/02676591251319684

Olivia Liu, Philip Y Sun, Syed A Ahmad, Andrew Kalra, Amy Feng, Glenn J R Whitman, Bo Soo Kim, Sung-Min Cho

{"title":"Characteristics and risk factors of delirium in patients on veno-arterial extracorporeal membrane oxygenation.","authors":"Olivia Liu, Philip Y Sun, Syed A Ahmad, Andrew Kalra, Amy Feng, Glenn J R Whitman, Bo Soo Kim, Sung-Min Cho","doi":"10.1177/02676591251319684","DOIUrl":"https://doi.org/10.1177/02676591251319684","url":null,"abstract":"Purpose: Sparse data exist on delirium in VA-ECMO. We aim to describe the characteristics, risk factors, and outcomes of delirium in VA-ECMO.Methods: We retrospectively reviewed adults's electronic medical records on VA-ECMO in our ECMO registry in 2016-2022. Delirium was assessed by the Confusion Assessment Method for the intensive care unit when patients scored -3 or above on the Richmond Agitation-Sedation Scale. The primary outcomes were delirium prevalence and the proportion of delirium-present days while on VA-ECMO support. Multivariable logistic regression was used to evaluate delirium risk factors.Results: Of 208 patients (median [interquartile range] age: 53 [40-62]), 138 (66.3%) had delirium during ECMO. Delirium occurred on day 2.5 [1.0-7.0] of ECMO and was detected in 42% [20%-66%] of ECMO days. There were no differences in acute brain injury (24% vs 33%, p = .34) between patients with and without delirium. Survival analysis showed no significant association between delirium and 30-day mortality (p = .24). In multivariable analysis, ECMO day 1 arterial carbon dioxide partial pressure (adjusted odds ratio [aOR] = 1.29; 95% CI = 1.03-1.73), number of sedatives (aOR = 2.67; 95% CI = 1.68-2.95), and African American race/ethnicity (aOR = 16.45; 95% CI = 9.65-22.51) were associated with delirium.Conclusions: Delirium was present in 66.3% of VA-ECMO patients and was detected early during ECMO. Modifiable risk factors included multiple sedative agents and early hypercapnia. Delirium did not increase risk for mortality.","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251319684"},"PeriodicalIF":1.1,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modifying veno - venous extra corporeal membrane oxygenation management for situs inversus totalis - A case report.

IF 1.1 4区医学

Perfusion-Uk Pub Date : 2025-03-02 DOI: 10.1177/02676591251320851

Rajesh Kasimahanti, K Venkateswara Rao, Dodda Sai Ramadevi, Mallela Balaji, Atchyutha Rao Gongada

{"title":"Modifying veno - venous extra corporeal membrane oxygenation management for situs inversus totalis - A case report.","authors":"Rajesh Kasimahanti, K Venkateswara Rao, Dodda Sai Ramadevi, Mallela Balaji, Atchyutha Rao Gongada","doi":"10.1177/02676591251320851","DOIUrl":"https://doi.org/10.1177/02676591251320851","url":null,"abstract":"IntroductionSitus inversus totalis is a rare condition affecting 1 in 10,000 individuals, in which the heart and abdominal organs are reversed. This mirrored arrangement of the great vessels presents unique challenges for vascular access during extracorporeal membrane oxygenation (ECMO).Case ReportA 41-year-old male presented with a fever, cough, and shortness of breath. Initial chest radiography revealed bilateral infiltrates (right more than left) and dextrocardia, while computed tomography of the chest and abdomen confirmed situs inversus totalis. The patient required venovenous ECMO for refractory hypoxemia. The ECMO setup was modified with an access cannula placed in the left femoral vein and a return cannula inserted into the left internal jugular vein. Bronchoscopy performed for lung collapse revealed a bilobed right lung and trilobed left lung. After clinical improvement, ECMO support was weaned off after 9 days, and the patient was discharged after 28 days.ConclusionModifying the ECMO setup and adjusting management strategies are crucial for treating refractory hypoxemia in patients with situs inversus.","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251320851"},"PeriodicalIF":1.1,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hypobaric type oxygenators - physics and physiology. 低压氧合器--物理和生理学。

IF 1.1 4区医学

Perfusion-Uk Pub Date : 2025-03-01 Epub Date: 2024-02-07 DOI: 10.1177/02676591241232824

Phatiwat Chotimol, William Lansdowne, David Machin, Kressle Binas, Gianni D Angelini, Ben Gibbison

引用次数: 0

Meta-analysis of central and peripheral cannulation for type A aortic dissection. A 型主动脉夹层中央插管和外周插管的 Meta 分析。

IF 1.1 4区医学

Perfusion-Uk Pub Date : 2025-03-01 Epub Date: 2024-03-12 DOI: 10.1177/02676591241238865

Noritsugu Naito, Hisato Takagi

{"title":"Meta-analysis of central and peripheral cannulation for type A aortic dissection.","authors":"Noritsugu Naito, Hisato Takagi","doi":"10.1177/02676591241238865","DOIUrl":"10.1177/02676591241238865","url":null,"abstract":"Background: Acute type A aortic dissection necessitates rapid and effective arterial cannulation techniques for optimal outcomes. This meta-analysis compares the safety and effectiveness of direct aortic cannulation (AoC) with peripheral cannulation (PC) via the femoral or axillary arteries in aortic surgery for acute type A aortic dissection.Methods: A systematic review following PRISMA guidelines identified 10 retrospective studies encompassing 2518 patients (961 AoC, 1557 PC). Pooled odds ratios (OR) with 95% confidence intervals (CI) were calculated to analyze perioperative characteristics, short-term mortality rates, and postoperative complications including stroke and acute kidney injury.Results: Short-term mortality did not significantly differ between AoC and PC (OR [95% CI] = 0.78 [0.61-1.01], p = .06). Likewise, postoperative stroke (OR [95% CI] = 0.86 [0.63-1.17], p = .33) nor acute kidney injury (OR [95% CI] = 1.11 [0.89-1.37], p = .35) showed no significant differences. AoC exhibited shorter operation time whereas there were no significant differences in aortic cross clamp time and cardiopulmonary bypass time between both groups. Our meta-regression analysis, considering the distal extent of aortic replacement, indicated that variations in aortic replacement rates did not significantly impact the observed outcomes.Conclusion: AoC is a viable alternative to PC for acute type A aortic dissection. While both approaches offer comparable outcomes, AoC's advantage in shorter operation time warrants thoughtful consideration in clinical practice.","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"417-430"},"PeriodicalIF":1.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140111968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extracorporeal cardio-pulmonary resuscitation in a patient with missed diagnosis of sodium nitrite intoxication. 一名亚硝酸钠中毒漏诊患者的体外心肺复苏术。

IF 1.1 4区医学

Perfusion-Uk Pub Date : 2025-03-01 Epub Date: 2024-03-14 DOI: 10.1177/02676591241240036

Francesco Gaiani, Marco Giani, Beatrice Vergnano, Jeff Sardella, Fabrizio Cappellini, Marco Casati, Matteo Pozzi, Giuseppe Foti

{"title":"Extracorporeal cardio-pulmonary resuscitation in a patient with missed diagnosis of sodium nitrite intoxication.","authors":"Francesco Gaiani, Marco Giani, Beatrice Vergnano, Jeff Sardella, Fabrizio Cappellini, Marco Casati, Matteo Pozzi, Giuseppe Foti","doi":"10.1177/02676591241240036","DOIUrl":"10.1177/02676591241240036","url":null,"abstract":"Introduction: Critical poisoning with sodium nitrite (NaNO2) can present challenges in promptly identifying and managing acute methemoglobinemia.Case report: We report the case of an overt self-intoxication by an initially unknown agent, leading to cardiac arrest. Despite prodromal signs of cyanosis, coma, desaturation, and hypotension, methemoglobinemia went unrecognized during extracorporeal cardiopulmonary resuscitation (ECPR) as the point-of-care test failed to provide methemoglobin levels, leading to untreated methemoglobinemia. The blood flowing through the oxygenator notably maintained the same brown colour. Return of spontaneous circulation was never achieved, and the patient was declared dead after 60 min of unsuccessful resuscitation. Cause of death by means of NaNO2 voluntary ingestion was later clarified and confirmed by postmortem finding of elevated nitrite and nitrate concentration.Conclusions: This case highlights the risk of failure of ECPR in the context of cardiac arrest due to methemoglobinemia, emphasizing the critical need for prompt recognition of the causative agent and early administration of antidotes.","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"519-522"},"PeriodicalIF":1.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140133101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aortic root enlargement and replacement of the ascending aorta in type 0 aortic valve stenosis. 0 型主动脉瓣狭窄的主动脉根部扩大和升主动脉置换术。

IF 1.1 4区医学

Perfusion-Uk Pub Date : 2025-03-01 Epub Date: 2024-02-07 DOI: 10.1177/02676591241233143

Clara Großmann, Ihor Krasivskyi, Ilija Djordjevic, Mariya Mihaylova, Thorsten Wahlers, Kaveh Eghbalzadeh

引用次数: 0

Utilizing cell salvage devices to return blood post extracorporeal membrane oxygenation circuit decannulation, A Letter to the Editor. 利用细胞抢救设备回输体外膜肺氧合回路拔管后的血液，致编辑的一封信。

IF 1.1 4区医学

Perfusion-Uk Pub Date : 2025-03-01 Epub Date: 2024-03-14 DOI: 10.1177/02676591241238859

Mazen F Odish, Samira Najmaii, Cassia Yi, Travis L Pollema

引用次数: 0

Letter re: Loss of pioneer physician perfusionist. 关于：先驱灌注医师去世的信函。

IF 1.1 4区医学

Perfusion-Uk Pub Date : 2025-03-01 Epub Date: 2024-03-13 DOI: 10.1177/02676591241238873

Dereck Wheeldon

引用次数: 0

Computational fluid dynamics in cardiac surgery and perfusion: A review. 心脏手术和灌注中的计算流体力学：综述。

IF 1.1 4区医学

Perfusion-Uk Pub Date : 2025-03-01 Epub Date: 2024-06-07 DOI: 10.1177/02676591241239277

Chiara Catalano, Fabrizio Crascì, Silvia Puleo, Roberta Scuoppo, Salvatore Pasta, Giuseppe M Raffa

{"title":"Computational fluid dynamics in cardiac surgery and perfusion: A review.","authors":"Chiara Catalano, Fabrizio Crascì, Silvia Puleo, Roberta Scuoppo, Salvatore Pasta, Giuseppe M Raffa","doi":"10.1177/02676591241239277","DOIUrl":"10.1177/02676591241239277","url":null,"abstract":"Cardiovascular diseases persist as a leading cause of mortality and morbidity, despite significant advances in diagnostic and surgical approaches. Computational Fluid Dynamics (CFD) represents a branch of fluid mechanics widely used in industrial engineering but is increasingly applied to the cardiovascular system. This review delves into the transformative potential for simulating cardiac surgery procedures and perfusion systems, providing an in-depth examination of the state-of-the-art in cardiovascular CFD modeling. The study first describes the rationale for CFD modeling and later focuses on the latest advances in heart valve surgery, transcatheter heart valve replacement, aortic aneurysms, and extracorporeal membrane oxygenation. The review underscores the role of CFD in better understanding physiopathology and its clinical relevance, as well as the profound impact of hemodynamic stimuli on patient outcomes. By integrating computational methods with advanced imaging techniques, CFD establishes a quantitative framework for understanding the intricacies of the cardiac field, providing valuable insights into disease progression and treatment strategies. As technology advances, the evolving synergy between computational simulations and clinical interventions is poised to revolutionize cardiovascular care. This collaboration sets the stage for more personalized and effective therapeutic strategies. With its potential to enhance our understanding of cardiac pathologies, CFD stands as a promising tool for improving patient outcomes in the dynamic landscape of cardiovascular medicine.","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"362-370"},"PeriodicalIF":1.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141288824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0