Perfusion-UkPub Date : 2025-05-14DOI: 10.1177/02676591251340967
Alexander L Chen, Matthew Robbins, Sean Masters, Elizabeth Boudiab, Daniel Finn, Emanuela Peshel, Gregory Thomas, Diane Studzinski, Steven Truscott, Courtney Watterworth, Nathan Novotny, Felicia Ivascu, Anthony Iacco
{"title":"Examining the role of thromboelastography in patients with COVID-19.","authors":"Alexander L Chen, Matthew Robbins, Sean Masters, Elizabeth Boudiab, Daniel Finn, Emanuela Peshel, Gregory Thomas, Diane Studzinski, Steven Truscott, Courtney Watterworth, Nathan Novotny, Felicia Ivascu, Anthony Iacco","doi":"10.1177/02676591251340967","DOIUrl":"https://doi.org/10.1177/02676591251340967","url":null,"abstract":"<p><p>BackgroundCOVID-19 causes a severe respiratory distress syndrome. Systemic inflammation and hypercoagulability are common. These findings are often evaluated with non-specific markers, including CRP, D-dimer, and fibrinogen. We sought to evaluate thromboelastography (TEG) to better understand this complex coagulopathy.MethodsWe conducted a prospective observational study analyzing TEG results in hospitalized patients with COVID-19. TEG was performed on admission and at pre-set intervals. Based on the TEG findings, patients were deemed \"hypercoagulable\" or \"not hypercoagulable.\" Clinical outcomes were recorded.Results88 patients were evaluated. 78/88 (89%) were hypercoagulable. 10% of the hypercoagulable group (8/78) died compared to none in the non-hypercoagulable group (0/10), with thrombotic events occurring in 9% (8/88), a higher requirement for O2 support in 19% (17/88), and prolonged length of stay exceeding 4 days for 74% (65/88). No statistical significant differences were observed between the groups for any of the four adverse events. Patients with complete fibrinolysis shutdown (Ly30 = 0) had more thrombotic events than those with Ly30 > 0 (30% vs 0%, <i>p</i> = .03).ConclusionPatients with COVID-19 are often hypercoagulable based upon specific TEG parameters. While many TEG parameters are not associated with adverse outcomes, complete fibrinolysis shutdown is associated with an increased risk of thrombotic events. Further studies are warranted to assess the utility of TEG in this population.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251340967"},"PeriodicalIF":1.1,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-05-09DOI: 10.1177/02676591251340970
Ishaq Ibrahim Najmuddin, P Sainath, Vaibhav Krishna Pillai
{"title":"Del Nido cardioplegia in adult cardiac surgery: A narrative review.","authors":"Ishaq Ibrahim Najmuddin, P Sainath, Vaibhav Krishna Pillai","doi":"10.1177/02676591251340970","DOIUrl":"https://doi.org/10.1177/02676591251340970","url":null,"abstract":"<p><p>Myocardial protection during cardiac surgery is crucial for preventing ischemia-reperfusion injury and preserving myocardial function. Cardioplegia, a solution used to induce electromechanical cardiac arrest, is the fundamental method for myocardial protection during on-pump procedures. Del Nido cardioplegia, developed in the 1990s, has gained increasing popularity in adult cardiac surgeries over the past two decades. Del Nido cardioplegia is a crystalloid-based solution used to achieve depolarized arrest. Its mechanism of action also involves preventing intracellular calcium overload, a key driver of reperfusion injury. Numerous studies have evaluated the safety and efficacy of del Nido cardioplegia in adult cardiac surgeries, including coronary artery bypass grafting and valve procedures. Compared to standard blood cardioplegia, del Nido cardioplegia has demonstrated reduced hemodilution, transfusion requirements and shorter cardiopulmonary bypass times due to its extended arrest duration. Many studies have reported lower levels of myocardial injury biomarkers and improved myocardial functional recovery with del Nido cardioplegia. It has also been associated with reduced defibrillation requirements, which is attributable to the antiarrhythmic effects of lidocaine. While some studies have reported no significant differences in outcomes between del Nido cardioplegia and blood cardioplegia, others have favored del Nido cardioplegia in terms of myocardial protection, postoperative cardiac function, and perioperative morbidity. The choice between cardioplegia solutions remains subjective and dependent on surgeon preference and institutional practices. However, del Nido cardioplegia has emerged as an acceptable alternative to traditional cardioplegia, offering potential advantages in adult cardiac surgeries.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251340970"},"PeriodicalIF":1.1,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-05-08DOI: 10.1177/02676591251340942
Polychronis Antonitsis, Helena Argiriadou, Anna Gkiouliava, Apostolos Deliopoulos, Stylianos Mimikos, Sotiria Gilou, Despoina Sarridou, Christos Voucharas, Georgios Karapanagiotidis, Kyriakos Anastasiadis
{"title":"The value of cerebral and somatic near-infrared spectroscopy within an integrated tissue perfusion monitoring strategy in cardiac surgery: A prospective pilot study.","authors":"Polychronis Antonitsis, Helena Argiriadou, Anna Gkiouliava, Apostolos Deliopoulos, Stylianos Mimikos, Sotiria Gilou, Despoina Sarridou, Christos Voucharas, Georgios Karapanagiotidis, Kyriakos Anastasiadis","doi":"10.1177/02676591251340942","DOIUrl":"https://doi.org/10.1177/02676591251340942","url":null,"abstract":"<p><p>IntroductionWe sought to evaluate cerebral and somatic oximetry in an integrated tissue perfusion monitoring strategy.MethodThirty adult patients undergoing full-spectrum cardiac surgery with Minimal Invasive Extracorporeal Circulation (MiECC) were recruited. We simultaneously assessed the adequacy of tissue perfusion with near-infrared spectroscopy (NIRS) for cerebral and tissue oximetry, cerebral autoregulation monitoring (COx), sublingual microcirculation with video microscopy and real-time in-line metabolic monitoring during cardiopulmonary bypass. The primary endpoint of the study was to evaluate the diagnostic accuracy of NIRS cerebral desaturation in predicting a global perfusion-related adverse clinical event.ResultsCerebral oximetry showed the higher positive and negative predicting values (50% and 67%, respectively) in detecting a tissue perfusion-related adverse outcome. Somatic oximetry was related to higher values compared to cerebral (<i>p</i> < .001) and followed a different trend. ROC analysis calculated a cutoff value of 22 for right-sided cerebral desaturation and 32 for cumulative left- and right-sided desaturation as a sensitive predictor of hyperlactemia. Microcirculatory parameters were impaired after induction of anesthesia, while they were preserved during cardiopulmonary bypass.ConclusionsNIRS cerebral oximetry represents a useful tissue perfusion monitoring tool. An AUC cutoff value of 22 for a single hemisphere and 32 bilaterally correlate with hyperlactemia and may serve as alarm for prompt action.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251340942"},"PeriodicalIF":1.1,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-05-07DOI: 10.1177/02676591251340933
Bennett Weinerman, Soon Bin Kwon, Tammam Alalqum, Daniel Nametz, Murad Megjhani, Eunice Clark, Caleb Varner, Eva W Cheung, Soojin Park
{"title":"Leveraging pediatric veno-arterial extra corporeal membrane oxygenation parameters to identify early risk factors for mortality.","authors":"Bennett Weinerman, Soon Bin Kwon, Tammam Alalqum, Daniel Nametz, Murad Megjhani, Eunice Clark, Caleb Varner, Eva W Cheung, Soojin Park","doi":"10.1177/02676591251340933","DOIUrl":"https://doi.org/10.1177/02676591251340933","url":null,"abstract":"<p><p>ObjectivePediatric Veno-Arterial Extra Corporeal Membrane Oxygenation (VA ECMO) can be a lifesaving technology; however, it is associated with high mortality. A successful VA ECMO course requires attention to multiple aspects of patient care; yet often overlooked are ECMO flow parameters. Early, potentially modifiable, risk factors associated with patient mortality should be scrutinized in patients requiring VA ECMO.MethodRetrospective single center experience of pediatric patients requiring VA ECMO from January 2021 to October 2023. Laboratory and ECMO flow parameters were extracted from the patients record and analyzed. Risk factors were analyzed using a Cox proportion hazard regression, and a multivariate regression.Main ResultsThere were 45 patients studied. Overall survival was 51%. Upon uncorrected analysis there were no significant differences between the patients who survived and those who died during their hospital admission. Utilizing a Cox proportion hazard regression, platelet count, fibrinogen level, and creatinine level normalized to age within the first 24 hours of a patients ECMO course were significant risk factors for hospital mortality. We did not find that ECMO flow parameters were significantly associated with mortality within the first 24 hours.SignificanceAlthough we did not find a significant difference among ECMO flow parameters in this study, this work highlights that granular ECMO flow data can be incorporated to risk analysis profiles and potential modeling in pediatric VA ECMO. This study demonstrated that when controlling for ECMO flow parameters, kidney dysfunction and clotting regulation are associated with pediatric VA ECMO mortality.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251340933"},"PeriodicalIF":1.1,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-05-07DOI: 10.1177/02676591251340938
San-Mari van Delft-van Deventer, Marco C Stehouwer, Wim van Oeveren
{"title":"Comparison of two different autotransfusion devices: An ex-vivo study.","authors":"San-Mari van Delft-van Deventer, Marco C Stehouwer, Wim van Oeveren","doi":"10.1177/02676591251340938","DOIUrl":"https://doi.org/10.1177/02676591251340938","url":null,"abstract":"<p><p>IntroductionDuring surgery, blood is recovered from the surgical field and the autotransfusion device separates and washes the red blood cells (RBC's) after which these can be retransfused to the patient. Autotransfusion devices differ strongly in separation method and washing settings, which may lead to different RBC recovery rates and removal rates of contaminants. The objective of this study was to compare the autoLog IQ<sup>TM</sup> (Medtronic) and the Xtra<sup>®</sup> (LivaNova) in terms of RBC recovery, quality of the processed blood and processing time.MethodsHuman blood was heparinised and processed with both autotransfusion devices according to their standard protocols. Blood samples were taken from the collection reservoir and from the transfusion bag and analyzed for cell count, heparin removal and cell injury.ResultsThe RBC recovery rates for both devices was 93%. Heparin was almost completely removed in both devices with >99.9%. The autoLog IQ<sup>TM</sup> showed significantly better removal of platelets (autoLog IQ vs Xtra; 86.1 ± 2.7 and 78.6 ± 4.4%, <i>p</i> = 0.01) and of leukocytes (autoLog IQ vs Xtra; 39.6 ± 2.7 and 13.4 ± 5.7%, <i>p</i> < 0.001). No other significant differences were observed in removal rates. The volume of RBC concentrated per minute was faster for the Xtra<sup>®</sup> (autoLog IQ vs Xtra, 21 ± 3 and 27 ± 2 mL RBC/min, <i>p</i> = 0.007).ConclusionsIn this study both the autoLog IQ<sup>TM</sup> and the Xtra<sup>®</sup> showed similar RBC recovery rates of 93% and almost all heparin was eliminated. The washing quality of the autoLog IQ<sup>TM</sup> device appears to be better, with better removal of platelets and leukocytes. Although both the autoLog IQ<sup>TM</sup> and the Xtra<sup>®</sup> devices use very different separation techniques and washing protocols, the difference in processing speed and various markers for cell damage in the end product seems trivial.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251340938"},"PeriodicalIF":1.1,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-05-04DOI: 10.1177/02676591251340971
Xiuli Jiang, Xiaoyu Zhou, Lei Yao, Lu Li, Tianyu Gu
{"title":"The effects of del Nido cardioplegia combined with dexmedetomidine on cardiac surgery with cardiopulmonary bypass.","authors":"Xiuli Jiang, Xiaoyu Zhou, Lei Yao, Lu Li, Tianyu Gu","doi":"10.1177/02676591251340971","DOIUrl":"https://doi.org/10.1177/02676591251340971","url":null,"abstract":"<p><p>ObjectiveTo evaluate the effects of dexmedetomidine administration and the use of del Nido cardioplegia in reducing the incidence of atrial fibrillation (AF) and delirium during the perioperative period.Methods448 patients were randomized into two groups: the treatment group received dexmedetomidine combined with del Nido cardioplegia, and the control group received normal saline placebo combined with Buckberg traditional cardioplegia. Each group included 224 patients. The occurrence of AF and delirium within 5 days after surgery, as well as other intraoperative and postoperative indicators, were noted.ResultsThere were no significant differences in preoperative indicators between the two groups. The incidences of AF and delirium events were significantly higher in the control group than in the treatment group.ConclusionWe found that del Nido cardioplegia combined with dexmedetomidine was safe in cardiac surgery with CPB and effectively reduced the incidence of postoperative AF and delirium.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251340971"},"PeriodicalIF":1.1,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-05-01Epub Date: 2024-06-17DOI: 10.1177/02676591241260860
Antonio D'Errico Ramirez, Vito Giovanni Ruggieri
{"title":"Mitral bioprosthesis early dysfunction treated with transapical valvuloplasty during V-A ECMO.","authors":"Antonio D'Errico Ramirez, Vito Giovanni Ruggieri","doi":"10.1177/02676591241260860","DOIUrl":"10.1177/02676591241260860","url":null,"abstract":"<p><p>We report the case of a 61-year-old male who had complications with a mitral valve (MV) bioprosthesis replacement by post-cardiotomy shock leading to VA ECMO implantation. The patient suffered early bioprosthetic valve failure owing to early thrombosis. The complication was successfully treated with a MV bioprosthesis transapical balloon valvuloplasty that restored normal leaflet mobility.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"1038-1040"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141332359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-05-01Epub Date: 2024-08-12DOI: 10.1177/02676591241271995
Xiumei Chen, Lipeng Zhang, Fan Zhang, Xuemei Li, Hui Li
{"title":"Application of targeted nursing intervention in patients undergoing synchronous carotid endarterectomy and coronary artery bypass grafting.","authors":"Xiumei Chen, Lipeng Zhang, Fan Zhang, Xuemei Li, Hui Li","doi":"10.1177/02676591241271995","DOIUrl":"10.1177/02676591241271995","url":null,"abstract":"<p><p>ObjectivesTo investigate the effect of targeted nursing intervention on the short-term prognosis of patients with coronary heart disease and carotid artery stenosis undergoing synchronous coronary artery bypass grafting (CABG) and carotid endarterectomy (CEA).MethodsA total of 58 patients who received OPCABG + CEA from February 2018 to May 2021 at the Beijing Anzhen Hospital were selected as the study subjects. They were randomly divided into two groups, with 29 patients in each group. The control group received routine postoperative nursing care, while the observation group received targeted nursing intervention in addition to the routine care. The incidence of postoperative stroke and the length of postoperative stay were observed.ResultsThere were no statistically significant differences in baseline data between the two groups. Postoperative acute stroke occurred in 2 cases (6.9%) in the control group and 0 cases in the observation group, although this difference was not statistically significant. The median postoperative hospital stay was 13 days in the control group, with the earliest discharge at 10 days. In the observation group, the median postoperative hospital stay was 10 days, with the earliest discharge on the 8th day. This difference was statistically significant.ConclusionsTargeted nursing intervention can improve the short-term prognosis of patients with coronary heart disease and carotid artery stenosis undergoing OPCABG + CEA, and it can also shorten the length of postoperative hospital stay.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"1057-1061"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-05-01Epub Date: 2024-07-25DOI: 10.1177/02676591241268395
Ajami Gikandi, Jean M Connors, Christoph G Nabzdyk, Marco A Zenati
{"title":"Perioperative risks associated with administration of andexanet alfa during emergency cardiac surgery with circulatory arrest.","authors":"Ajami Gikandi, Jean M Connors, Christoph G Nabzdyk, Marco A Zenati","doi":"10.1177/02676591241268395","DOIUrl":"10.1177/02676591241268395","url":null,"abstract":"<p><p>This case report describes the perioperative course of a patient undergoing emergency repair of acute type A thoracic aortic dissection. Andexanet alfa was administered intraoperatively to obtain a dry operative field for right axillary artery exposure and cannulation. Andexanet alfa-induced heparin resistance resulted in cardiopulmonary bypass circuit and pericardial thrombosis requiring more than 400,000 units of unfractionated heparin and antithrombin III to overcome. Postoperatively, excessive chest tube output was observed secondary to protracted heparin rebound requiring continuous dosing of protamine. This case demonstrates the significant challenging perioperative, not just intraoperative, hazards associated with intraoperative andexanet alfa use during emergency cardiac surgery with cardiopulmonary bypass.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"1045-1048"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perfusion-UkPub Date : 2025-05-01Epub Date: 2024-07-21DOI: 10.1177/02676591241265052
Rachel Hillner, Luke Perry, Natalie Hill, Aditya V Badheka, Venkat Keshav Chivukula
{"title":"EXCOR membrane motion analyzer (EMMA) to quantify and assess hemodynamic performance of the EXCOR pediatric heart assist device.","authors":"Rachel Hillner, Luke Perry, Natalie Hill, Aditya V Badheka, Venkat Keshav Chivukula","doi":"10.1177/02676591241265052","DOIUrl":"10.1177/02676591241265052","url":null,"abstract":"<p><p>BackgroundPediatric heart failure is associated with high mortality rates and is a current clinical burden. There is only one FDA approved pediatric VAD, Berlin Heart EXCOR, for treatment. Thrombo-embolic complications are a significant clinical challenge, which can lead to devastating complications such as stroke and impair efficient EXCOR function. Currently, clinicians perform largely qualitative periodic assessment of EXCOR operation by observing the motion of a rapidly moving membrane, which can be prone to human error and can lead to missing out on crucial information.MethodsIn this study, we design and implement a quantitative early warning system for accurate and quantitative assessment of the EXCOR membrane, named EXCOR Membrane Motion Analyzer (EMMA). Using a combination of image analysis, computer vision and custom designed algorithm, we perform rigorous frame by frame analysis of EXCOR membrane video data. We developed specialized metrics to identify relative smoothness between successive peaks, time between peaks and overall smoothness indicators to quantify and compare between multiple cases.ResultsOur results demonstrate that EMMA can successfully identify the motion and wrinkles on each video frame and quantify the smoothness and identify the phases of each cardiac cycle. Moreover, EMMA can obtain the smoothness of each frame and the temporal evolution of membrane smoothness across all image frames for the video sequence.ConclusionsEMMA allows for a fast, accurate, quantitative assessment to be completed and reduces user error. This enables EMMA to be used effectively as an early warning system to rapidly identify device abnormalities.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"898-906"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}