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ECMO bi-femoral distal perfusion as a salvage option in femoral artery dissection complication. 将 ECMO 双股动脉远端灌注作为股动脉夹层并发症的抢救方案。
IF 1.1 4区 医学
Perfusion-Uk Pub Date : 2025-09-01 Epub Date: 2024-11-26 DOI: 10.1177/02676591241303841
Michael Antonopoulos, Ioannis Nenekidis, Konstantinos Perreas, Stavros Dimopoulos
{"title":"ECMO bi-femoral distal perfusion as a salvage option in femoral artery dissection complication.","authors":"Michael Antonopoulos, Ioannis Nenekidis, Konstantinos Perreas, Stavros Dimopoulos","doi":"10.1177/02676591241303841","DOIUrl":"10.1177/02676591241303841","url":null,"abstract":"","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"1525-1526"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142734188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acquired ineffective erythropoiesis in pediatric ECMO patients: Higher than anticipated serum EPO levels and lower than anticipated reticulocytes counts were associated with mortality. 儿科 ECMO 患者获得性红细胞生成功能低下:血清 EPO 水平高于预期和网织红细胞计数低于预期与死亡率有关。
IF 1.1 4区 医学
Perfusion-Uk Pub Date : 2025-09-01 Epub Date: 2024-11-15 DOI: 10.1177/02676591241300956
Zachary Weber, Christian C Yost, Mark Cody, Jonathan M King, Cody Henderson, Robert D Christensen, Nicholas R Carr
{"title":"Acquired ineffective erythropoiesis in pediatric ECMO patients: Higher than anticipated serum EPO levels and lower than anticipated reticulocytes counts were associated with mortality.","authors":"Zachary Weber, Christian C Yost, Mark Cody, Jonathan M King, Cody Henderson, Robert D Christensen, Nicholas R Carr","doi":"10.1177/02676591241300956","DOIUrl":"10.1177/02676591241300956","url":null,"abstract":"<p><p>BackgroundECMO plays a crucial role in treating severe respiratory and cardiac failure in pediatric patients. However, its impact on the regulation of erythropoietin (EPO) and erythropoiesis remains poorly understood. Factors such as improved oxygenation, inflammation, and hemodilution associated with ECMO treatment may influence EPO production and erythropoiesis. This study aimed to examine the effects of ECMO on EPO regulation and erythropoiesis in pediatric patients.MethodsThis retrospective study serially quantified EPO serum levels, measured markers of erythropoiesis, and tabulated clinical outcomes of pediatric ECMO patients. Descriptive statistics and Pearson correlation coefficients were used to identify associations between biomarkers and clinical care parameters.ResultsPreliminary findings suggest a disconnection between elevated EPO levels and reduced markers of erythropoiesis or iron metabolism, indicating ineffective erythropoiesis. Patients receiving more than 10 mL/kg/day of RBC transfusions had higher reticulocyte counts. Non-survivors had sustained elevations of EPO serum levels but reduced erythropoietic activity.ConclusionIn ECMO-treated pediatric patients, ineffective erythropoiesis is a significant concern and may be associated with higher mortality rates. Understanding the mechanisms behind this pathology could better inform clinical approaches and optimize management strategies. Further research is imperative to uncover the factors resulting in ineffective erythropoiesis in these patients and to develop targeted interventions.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"1423-1430"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recovery model for minimally invasive central cannulation, cardiopulmonary bypass, and cardioplegic arrest in quadrupeds. 四足动物微创中心插管、体外循环和心脏骤停的恢复模型。
IF 1.1 4区 医学
Perfusion-Uk Pub Date : 2025-09-01 Epub Date: 2024-12-17 DOI: 10.1177/02676591241309824
Matthew D Johnson, Lise Tchouta, Brianna L Spencer, Mark W Langley, Kristopher A Urrea, John M Toomasian, Joseph B Niman, Robert H Bartlett, Alvaro Rojas-Peña, Daniel H Drake
{"title":"Recovery model for minimally invasive central cannulation, cardiopulmonary bypass, and cardioplegic arrest in quadrupeds.","authors":"Matthew D Johnson, Lise Tchouta, Brianna L Spencer, Mark W Langley, Kristopher A Urrea, John M Toomasian, Joseph B Niman, Robert H Bartlett, Alvaro Rojas-Peña, Daniel H Drake","doi":"10.1177/02676591241309824","DOIUrl":"10.1177/02676591241309824","url":null,"abstract":"<p><p><i>Objectives:</i> Sternotomy is rarely performed for veterinary therapeutic or recovery models in quadrupeds because of difficulties with breathing, ambulation, and pain control. Central cannulation for cardiopulmonary bypass (CPB) is infrequent and typically performed through full thoracotomies. Experienced clinical surgeons and perfusionists should provide guidance for new therapeutic interventions and translational research. We sought to develop, validate, and detail a contemporary model for minimally-invasive central cannulation, CPB, and cardioplegic arrest. <i>Methods:</i> After induction of anesthesia and sterile preparation, a right second-interspace parasternal mini-thoracotomy was performed, the ascending aorta was cannulated using Seldinger technique, and a cardioplegia needle was placed. A dual-stage cannula was introduced through the right atrial appendage and CPB commenced. The aorta was clamped and Buckberg 4:1 induction cardioplegia was administered. Arrest was maintained for 30 minutes. CPB was discontinued after 2 hours and the great vessels were decannulated. Hemostasis was achieved and the wound was closed. Initial recovery was accomplished in intensive care with subsequent transfer to the vivarium.<i>Results:</i> Ten consecutive Yorkshire swine (45 ± 5 kg) were minimally invasively placed on CPB including cardioplegic arrest using central cannulation through a right parasternal mini-thoracotomy. There was no operative or late mortality. Morbidity appeared minimal. Planned euthanasia and scheduled necropsy were performed to exclude clinically-occult major complications. None were identified. Following initial supervision, veterinary and resident surgeons completed the procedures autonomously with excellent results.<i>Conclusion:</i> The described protocols should facilitate safe veterinary cardiac surgical care and humane translational research.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"1317-1324"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The immunomodulatory effect of continuous ultrafiltration during pediatric cardiac surgery. 连续超滤在小儿心脏手术中的免疫调节作用。
IF 1.1 4区 医学
Perfusion-Uk Pub Date : 2025-09-01 DOI: 10.1177/02676591251374252
Joel David Bierer, Roger Stanzel, Mark Henderson, John Sapp, Pantelis Andreou, Jean S Marshall, David Horne
{"title":"The immunomodulatory effect of continuous ultrafiltration during pediatric cardiac surgery.","authors":"Joel David Bierer, Roger Stanzel, Mark Henderson, John Sapp, Pantelis Andreou, Jean S Marshall, David Horne","doi":"10.1177/02676591251374252","DOIUrl":"https://doi.org/10.1177/02676591251374252","url":null,"abstract":"<p><p>BackgroundCardiopulmonary bypass is associated with systemic inflammation during pediatric cardiac surgery and features elevated systemic concentrations of complement, cytokines and chemokines. The objective of this study is to quantify the immunologic efficacy of ultrafiltration (UF) used continuously throughout CPB.MethodsPediatric patients were enrolled in a single-arm prospective clinical study (NCT05154864) and received standard cardiac operations, CPB and subzero-balance ultrafiltration (SBUF) with an effluent extraction rate of 30 mL/kg/hr and conventional ultrafiltration (CUF). Paired arterial and UF effluent samples were taken at regular intervals during CPB and the concentration of 33 inflammatory mediators were measured. An exploratory counterfactual analysis assessed whether UF removed a significant amount of mediator mass using area under the curve (AUC), generalized linear mixed-effects models (GLMEM), and median fold change [95% CI] comparisons between observed data (UF) and reconstructed counterfactual data (no UF).ResultsForty consecutive eligible consenting patients participated; the majority were male (58%), age of 7.3 (1.7 - 39.0) months and weight of 6.7 (4.6 - 14.9) kg. All patients received UF therapy with effluent extraction of 155 (100 - 185) ml/kg during CPB. C3a, C5a, TNF, IL-1α, IL-1β, IL-1Ra, IL-2, IL-6, IL-10, CCL2, CCL3, CCL4, CXCL1, CXCL2, CXCL8, ET1, GM-CSF and TRAIL were detected in the UF effluent. In the counterfactual analysis, only C3a was significantly extracted by UF using AUC (<i>p</i> = 3.5 × 10<sup>-12</sup>), GLMEM (<i>p</i> = 2.3 × 10<sup>-87</sup>), and median fold change [95% CI] as C3a showed a decrease of -0.2 [-0.3 to 0] relative to CPB initiation, in the observed data, compared to the counterfactual with a median fold increase of 4.3 [3.1 - 5.3].ConclusionsUltrafiltration during pediatric CPB extracts cytokines and chemokines continuously throughout CPB with relatively low effectiveness. In an exploratory counterfactual analysis, C3a was the only inflammatory mediator meaningfully removed from the circulation by UF.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251374252"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inflammatory prognostic index predicts late mortality after surgical aortic valve replacement. 炎症预后指数预测主动脉瓣置换术后的晚期死亡率。
IF 1.1 4区 医学
Perfusion-Uk Pub Date : 2025-09-01 DOI: 10.1177/02676591251375717
Batuhan Yazıcı, Mustafa Can Kaplan, Zinar Apaydın, Alkım Ateşli Yazıcı, Barış Timur, İsa Can, Tural Muradlı, Alper Selim Kocaoğlu
{"title":"Inflammatory prognostic index predicts late mortality after surgical aortic valve replacement.","authors":"Batuhan Yazıcı, Mustafa Can Kaplan, Zinar Apaydın, Alkım Ateşli Yazıcı, Barış Timur, İsa Can, Tural Muradlı, Alper Selim Kocaoğlu","doi":"10.1177/02676591251375717","DOIUrl":"https://doi.org/10.1177/02676591251375717","url":null,"abstract":"<p><p>ObjectiveThis study aimed to investigate the prognostic value of the preoperative Inflammatory Prognostic Index (IPI) in predicting late mortality in patients undergoing isolated surgical aortic valve replacement (AVR).MethodsA retrospective, single-center cohort of 400 patients who underwent elective, isolated surgical AVR between 2015 and 2023 was analyzed. The IPI was calculated using the formula: C-reactive protein (CRP) × neutrophil-to-lymphocyte ratio (NLR) / albumin. Patients were stratified into low- and high-IPI groups based on an optimal cut-off value of 0.2588 determined via ROC analysis. Clinical characteristics, operative data, and outcomes were compared. Cox proportional hazards regression was used to identify independent predictors of late mortality.ResultsPatients with high IPI scores (≥0.2588) had significantly increased late mortality compared to those with low IPI (<0.2588) (10.3% vs 2.3%, <i>p</i> < .001). High IPI was associated with elevated CRP and neutrophils, and reduced albumin and lymphocytes. In univariate analysis, age, bioprosthesis use, and high IPI were significantly associated with late mortality. However, in multivariate analysis, only high IPI remained an independent predictor (HR = 3.405, 95% CI: 1.289-8.996, <i>p</i> = .013). Kaplan-Meier survival analysis confirmed lower long-term survival in the high-IPI group (<i>log-rank p</i> < .001).ConclusionPreoperative IPI is a simple, accessible, and independent predictor of late mortality after surgical AVR. Integrating IPI into preoperative risk assessment may improve long-term prognostic stratification and guide perioperative management.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"2676591251375717"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgery for a giant atherosclerotic left main trifurcation saccular coronary artery aneurysm. 巨大动脉粥样硬化性左主干三叉囊状冠状动脉瘤手术。
IF 1.1 4区 医学
Perfusion-Uk Pub Date : 2025-09-01 Epub Date: 2024-11-03 DOI: 10.1177/02676591241296714
Mehmet Cahit Saricaoglu, Yusuf Corbacioglu, Salih Anil Boga, Serenay Deniz, Irem Dincer, Ahmet Ruchan Akar
{"title":"Surgery for a giant atherosclerotic left main trifurcation saccular coronary artery aneurysm.","authors":"Mehmet Cahit Saricaoglu, Yusuf Corbacioglu, Salih Anil Boga, Serenay Deniz, Irem Dincer, Ahmet Ruchan Akar","doi":"10.1177/02676591241296714","DOIUrl":"10.1177/02676591241296714","url":null,"abstract":"<p><p>Aneurysms of the left main coronary artery are rare clinical entities with an incidence of 0.1%. We herein report a case of left main trifurcation aneurysm in a 57-year-old woman whose coronary angiography demonstrated a giant saccular aneurysm of trifurcation of the left main coronary artery, measuring 32 × 21 mm with tight post-aneurysmal stenosis in the intermediate artery. The patient underwent coronary artery bypass grafting following the resection of CAA and reconstruction with saphenous vein roof-plasty, which ensured the preservation of the native coronary vasculature. At the 6-month follow-up, she remained asymptomatic and preserved preoperative left ventricular function.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"1504-1507"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiopulmonary bypass of acute type A aortic dissection during pregnancy at the 20th gestational week with maternal and foetal survival: A case report. 妊娠 20 周时急性 A 型主动脉夹层的心肺旁路手术,母体和胎儿存活:病例报告。
IF 1.1 4区 医学
Perfusion-Uk Pub Date : 2025-09-01 Epub Date: 2024-11-05 DOI: 10.1177/02676591241297319
Ling Wang, Jie Yi, Fang-Fang Qin, Cai-Xia Liu, Liu Huang
{"title":"Cardiopulmonary bypass of acute type A aortic dissection during pregnancy at the 20th gestational week with maternal and foetal survival: A case report.","authors":"Ling Wang, Jie Yi, Fang-Fang Qin, Cai-Xia Liu, Liu Huang","doi":"10.1177/02676591241297319","DOIUrl":"10.1177/02676591241297319","url":null,"abstract":"<p><p>BackgroundType A acute aortic dissection, an aggressive and highly fatal disease, is particularly common among pregnant women and foetuses. This disease often occurs during the third trimester of pregnancy and the postpartum period.Case ReportThis case involves a female who was 20 weeks pregnant with type A acute aortic dissection. While maintaining pregnancy, the patient underwent Bentall surgery and Sun's procedure. The duration of circulatory arrest was a brief 4 min. The patient fully recovered 40 days after surgery and remained pregnant post-discharge. At the 38th gestational week, she delivered a healthy male infant via caesarean section.Clinical DiscussionGestational morbidity can have a serious impact on the safety of mothers and children. Currently, the shortest time reported for hypothermic circulatory arrest is 5 min. In this case, the lower body circulatory arrest was controlled to approximately 4 min during cardiopulmonary bypass while simultaneously safeguarding both individuals. Ideal strategies for cardiopulmonary bypass to reduce foetal risk include shorter cardiopulmonary bypass times, higher flow rates, and higher perfusion pressures. A reduction in the duration of hypothermic circulatory arrest further increases foetal survival rates.ConclusionsThe development of a rational cardiopulmonary bypass plan should be tailored to the physiological characteristics of the pregnant woman to ensure the safety of both the pregnant woman and the foetus, reduce complications, and improve the success rate of the operation.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"1508-1512"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Initial experience with pump controlled retrograde trial-off (PCRTO) veno-arterial extra corporeal membrane oxygenation in children. 在儿童中使用泵控逆行试管关闭(PCRTO)静脉-动脉体外膜氧合的初步经验。
IF 1.1 4区 医学
Perfusion-Uk Pub Date : 2025-09-01 Epub Date: 2024-11-14 DOI: 10.1177/02676591241300955
Anuradha P Menon, Janine C Koh, Siew Yan Teng, Tanee Chan, Masakazu Nakao
{"title":"Initial experience with pump controlled retrograde trial-off (PCRTO) veno-arterial extra corporeal membrane oxygenation in children.","authors":"Anuradha P Menon, Janine C Koh, Siew Yan Teng, Tanee Chan, Masakazu Nakao","doi":"10.1177/02676591241300955","DOIUrl":"10.1177/02676591241300955","url":null,"abstract":"<p><p>Pump Controlled Retrograde Trial Off (PCRTO) is a relatively new technique in trialing-off Veno-Arterial Extra Corporeal Membrane Oxygenation (VA-ECMO). Literature on the use of PCRTO in children remains scarce. We describe our centre's initial experience with PCRTO in a neonate and an older child and review its potential advantages and disadvantages compared to traditional weaning methods. More research and shared best practices are required in children to facilitate wider adoption of this technique.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"1516-1520"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Q-Fever endocarditis: Prosthetic valve infection in the absence of zoonotic exposure. Q热心内膜炎:没有人畜共患病接触的人工瓣膜感染。
IF 1.1 4区 医学
Perfusion-Uk Pub Date : 2025-09-01 Epub Date: 2024-11-22 DOI: 10.1177/02676591241303313
Walid Mohamed, Omar Dihmis, David Thirukumaran, Suvitesh Luthra
{"title":"Q-Fever endocarditis: Prosthetic valve infection in the absence of zoonotic exposure.","authors":"Walid Mohamed, Omar Dihmis, David Thirukumaran, Suvitesh Luthra","doi":"10.1177/02676591241303313","DOIUrl":"10.1177/02676591241303313","url":null,"abstract":"<p><p><i>Background:</i> Q-Fever is a rare condition with an often insidious presentation. Endocarditis is a serious complication of up to 5% of Q-Fever cases, with a higher incidence and mortality in patients with prosthetic valves.<i>Case-history:</i> A 67-year-old man presented with a 6-weeks history of breathlessness on a background of previous bioprosthetic aortic valve replacement in 2018. Subsequent echocardiograms showed severe eccentric aortic regurgitation, a 2 cm vegetation, and severely impaired biventricular function. Routine blood cultures were negative, but later PCR testing for non-culturable microorganisms, performed due to the high probability of endocarditis, was positive for <i>Coxiella Burnetii</i>. The patient denied any recent constitutional symptoms and previous exposure to animal reservoirs. He underwent a successful urgent redo sternotomy and aortic valve replacement with a bioprosthesis. Prosthetic valve PCR testing was positive for <i>Coxiella Burnetii</i>, and he completed a long antibiotic course with follow-up serology to guide therapy. Clinic follow-up 3 months later showed good recovery with no complications.<i>Conclusions:</i> This case emphasises the high index of suspicion and routine screening needed in culture-negative cases to diagnose Q-Fever endocarditis, especially in the absence of acute symptoms and exposure to known sources of transmission. The complexities in management and timing of surgery are discussed.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"1521-1524"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extended use of axillary impella 5.5 as a bridge to post-infarct ventricular septal defect repair. 将 5.5 型腋窝栓塞作为梗塞后室间隔缺损修复的桥梁。
IF 1.1 4区 医学
Perfusion-Uk Pub Date : 2025-09-01 Epub Date: 2024-11-13 DOI: 10.1177/02676591241300951
Vasiliki Gregory, Ariadne Zias, Ameesh Isath, David Spielvoge, Suguru Ohira
{"title":"Extended use of axillary impella 5.5 as a bridge to post-infarct ventricular septal defect repair.","authors":"Vasiliki Gregory, Ariadne Zias, Ameesh Isath, David Spielvoge, Suguru Ohira","doi":"10.1177/02676591241300951","DOIUrl":"10.1177/02676591241300951","url":null,"abstract":"<p><p>Post-infarct ventricular septal defect (VSD) carries high mortality. Since emergent repair of post-infarct VSD is challenging, hemodynamic stabilization utilizing temporary mechanical circulatory support crucially provides time to delay intervention and allows necessary scar tissue formation which improves the fragility of myocardium and leads to a definitive repair. To date, there remains no standard for achieving hemodynamic stability, including usage and mode of temporary mechanical circulatory support. We describe a patient with acute post-infarct VSD in cardiogenic shock successfully supported with Impella 5.5 for 67 days as a bridge to surgical repair and coronary artery bypass grafting.</p>","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"1513-1515"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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