Public Health最新文献

{"title":"Age heterogeneity in the association between malnutrition and early childhood development among children aged 0–5 years in a Chinese plateau area","authors":"Meiying Shen ,&nbsp;Yajie Li ,&nbsp;Zhuhong Cui ,&nbsp;Xianzhi Li","doi":"10.1016/j.puhe.2025.105737","DOIUrl":"10.1016/j.puhe.2025.105737","url":null,"abstract":"<div><h3>Objective</h3><div>Malnutrition damages the physical and cognitive development of children. This study aimed to examine age heterogeneity in the associations of malnutrition with early childhood development (ECD) outcomes in Tibet, China.</div></div><div><h3>Study design</h3><div>Cross-sectional study.</div></div><div><h3>Methods</h3><div>ECD was assessed by the Chinese version of the Age and Stage Questionnaires, Third Edition (ASQ-3). Logistic regression models were used to examine the associations between malnutrition and ECD outcomes.</div></div><div><h3>Results</h3><div>The Z-scores of HFA was significantly negatively associated with failure in any developmental domain (<em>OR</em> = 0.91, 95 % CI: 0.84, 0.99), the fine motor domain (<em>OR</em> = 0.82, 95 % CI: 0.74, 0.91) and the problem-solving domain (<em>OR</em> = 0.89, 95 % CI: 0.81, 0.98), while the Z-scores of WFH was significantly positively associated with failure in the gross motor domain (<em>OR</em> = 1.07, 95 % CI: 1.02, 1.13). Positive associations were observed between stunting and ECD indicators, with ORs of 1.62 (95 % CI: 1.05, 2.51) and 1.70 (95 % CI: 1.07, 2.70) for failing in any developmental domain and the problem-solving domain. Moreover, the effects of stunting on any developmental delay, the gross motor domain delay, and the problem-solving domain delay among children under 36 months of age were significantly higher than that aged 36 months and above (<em>P</em> value for difference &lt;0.05).</div></div><div><h3>Conclusions</h3><div>Stunting was associated with increased risk of failing in any domain or specific domain for ECD. A compressive intervention about improving the nutritional status of malnutrition children should be conducted to benefit children development, especially for those under 36 months of age.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"243 ","pages":"Article 105737"},"PeriodicalIF":3.9,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143904156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community-based health promotion interventions to reduce risk factors of non-communicable diseases among adolescent and young adults in low- and middle-income countries: A systematic review and meta-analysis.","authors":"Rajashekhar M, Mudita Joshi, Anuj Mundra, Rutuja Kolhe, Richard Kirubakaran, Abhishek V Raut, Mahalaqua Nazli Khatib","doi":"10.1016/j.puhe.2025.03.026","DOIUrl":"https://doi.org/10.1016/j.puhe.2025.03.026","url":null,"abstract":"<p><strong>Objective: </strong>To systematically review the effectiveness of community-based health promotion interventions in reducing risk factors for non-communicable diseases (NCDs) among adolescents and young adults in low- and middle-income countries (LMICs).</p><p><strong>Study design: </strong>Systematic review and meta-analysis.</p><p><strong>Methods: </strong>A systematic review followed a registered protocol (PROSPERO 2022 CRD42022369054). A comprehensive search was performed across the databases, including Cochrane Library, PubMed, and ScienceDirect, resulting in 6,523 studies, of which 18 articles met the inclusion criteria. Studies were selected based on rigorous eligibility criteria, focusing on community-based interventions targeting modifiable risk factors for NCDs among individuals aged 10-30 years. Data extraction and quality assessment were independently performed by two reviewers, with results synthesised according to PRISMA guidelines.</p><p><strong>Results: </strong>The review included studies on a variety of interventions, with outcomes indicating no reduction in smoking prevalence and increased fruit intake in intervention groups compared to controls. Legislative measures and community engagement were particularly effective in reducing smoking rates in some studies, while other outcomes showed improvements in physical activity, dietary habits, and psychological well-being. The interventions demonstrated high feasibility, reach, and acceptance, suggesting potential for scalability. However, mixed results for risk factor reduction highlight the need for tailored approaches.</p><p><strong>Conclusion: </strong>The effectiveness of community-based interventions in reducing NCD risk factors among adolescents and young adults in low- and middle-income countries (LMICs) remains uncertain, as outcomes differ across various demographics and types of interventions. Future research should prioritise long-term impacts, sustainable intervention models, and context-specific strategies, as well as cost-effectiveness, to improve the effectiveness of health promotion efforts.</p>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":" ","pages":"105714"},"PeriodicalIF":3.9,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the relationship between women's health autonomy and mental health in Senegal","authors":"Alex Bawuah ,&nbsp;Lalit Dzifa Kodzo","doi":"10.1016/j.puhe.2025.105746","DOIUrl":"10.1016/j.puhe.2025.105746","url":null,"abstract":"<div><h3>Objectives</h3><div>This study explores the relationship between women's healthcare autonomy and mental health in Senegal, where cultural and societal norms often marginalize women's autonomy. Recognizing autonomy as a crucial determinant of well-being, the study aims to evaluate how autonomy in health-related decision-making correlates with mental health.</div></div><div><h3>Study design</h3><div>Cross-sectional study.</div></div><div><h3>Methods</h3><div>A sample of 10,983 women (15–49 years) was drawn from the 2023 Senegal Continuous Demographic and Health Survey data. The outcome variable (mental health status) was assessed through three self-reported indicators, including depression symptoms, loss of interest, and suicidal thoughts. The main independent variable, women's health autonomy, was categorized into those with and without autonomy over healthcare decisions. Multivariable logistic regression models were applied to evaluate the relationship between women's health autonomy and their mental health status.</div></div><div><h3>Results</h3><div>Overall, 34.33 % of the women reported feeling sad/depressed, 27.68 % reported losing interest in anything and 21.55 % reported having suicidal thoughts. Also, only 10.73 % had autonomy over their healthcare decisions. Women with health autonomy were less likely to feel sad/depressed (AOR = 0.81, 95 % CI = 0.67–0.98), lose interest in anything (AOR = 0.78, 95 % CI = 0.65–0.94), and have suicidal thoughts (AOR = 0.69, 95 % CI = 0.52–0.91) compared to women without autonomy.</div></div><div><h3>Conclusions</h3><div>Women's healthcare autonomy is a significant protective factor against mental health challenges. Policies enhancing women's autonomy could improve mental health outcomes, highlighting a critical need for gender-responsive healthcare reforms in Senegal and similar contexts.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"244 ","pages":"Article 105746"},"PeriodicalIF":3.9,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143902400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spatial–temporal analysis of cervical cancer screening and social and health indicators in Brazil","authors":"M.L.S. Gomes ,&nbsp;V.R.F. Cestari ,&nbsp;R.S. Florêncio ,&nbsp;M. Yamamura ,&nbsp;J.O. Santos ,&nbsp;L.B.F. Sales ,&nbsp;R.R. Silva ,&nbsp;M.O.B. Oriá","doi":"10.1016/j.puhe.2025.105747","DOIUrl":"10.1016/j.puhe.2025.105747","url":null,"abstract":"<div><h3>Objective</h3><div>To identify the spatial-temporal patterns of cervical cancer (CC) screening in Brazil from 2013 to 2022 and its relationship with social and health indicators.</div></div><div><h3>Study design</h3><div>This ecological study uses data from the Cancer Information System (SISCAN) of the Brazilian Unified Health System's Department of Informatics.</div></div><div><h3>Methods</h3><div>The study analyzed women aged 25 to 64 who underwent CC screening in 5570 municipalities across Brazil. Global Moran's I and the Local Index of Spatial Autocorrelation (LISA) were employed to investigate clustering. The purely spatial scan statistic technique was used for spatial cluster detection. Temporal trends were assessed using joinpoint regression. GeoDa, SaTScan, GWR, and QGIS software were used for the analysis.</div></div><div><h3>Results</h3><div>The global clustering analysis of CC screening proportions revealed significant spatial autocorrelation (Moran's I = 0.530). Clusters of municipalities with low screening rates were significantly observed in the Northern (Amapá, Amazonas, Rondônia, Roraima) and Northeastern (Piauí, Pernambuco) regions. The Gini Index (β = −2.60), the Municipal Human Development Index (MHDI) (β = −10.5), and the Social Vulnerability Index (SVI) (β = −9.14) showed negative associations. Conversely, Family Health Strategy (FHS) coverage (β = 2.18) demonstrated a positive impact on screening rates. In terms of temporal trends, the screening proportion gradually increased from 5.4 % in 2014 to 10.5 % in 2022.</div></div><div><h3>Conclusion</h3><div>Areas with a high risk of low CC screening rates were identified in the Northern and Northeastern regions of Brazil, which are characterized by socioeconomic and demographic disparities, vulnerabilities, and inequalities.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"243 ","pages":"Article 105747"},"PeriodicalIF":3.9,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143894783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Problem gambling in the crypto era: A study of gambling motivations and cognitive distortions amongst cryptocurrency traders","authors":"T. Xu ,&nbsp;J.B. Grubbs ,&nbsp;S.W. Kraus","doi":"10.1016/j.puhe.2025.105741","DOIUrl":"10.1016/j.puhe.2025.105741","url":null,"abstract":"<div><h3>Objectives</h3><div>The rise of cryptocurrency trading has sparked global interest and raised concerns about its potential links to problematic gambling behaviours. This study examined the prevalence of problematic gambling amongst cryptocurrency traders and identified psychological predictors, focusing on gambling motivations and cognitive distortions.</div></div><div><h3>Study design</h3><div>Cross-sectional survey study using YouGov Opinion Polling's sample-matching methodology.</div></div><div><h3>Methods</h3><div>A sample of 700 cryptocurrency traders was drawn from a larger behavioural addiction project (<em>N</em> = 4363). Participants completed the Problem Gambling Severity Index (PGSI), Gambling Motives Questionnaire-Financial (GMQ-F), and Gambling Related Cognitions Scale (GRCS). Analyses included chi-square tests, one-way ANOVAs with Tukey's post-hoc tests, and multinomial logistic regression.</div></div><div><h3>Results</h3><div>Problematic gambling was identified in 33.7 % of traders, with 33.9 % classified as at-risk gambling and 32.4 % as non-problematic gambling. Enhancement motivation (OR = 1.60, 95 % CI [1.10, 2.34]) and interpretative bias (OR = 1.38, 95 % CI [1.06, 1.81]) positively predicted at-risk gambling, whereas social motivation showed protective effects (OR = 0.61, 95 % CI [0.41, 0.91]). Coping motivation strongly predicted problematic gambling (OR = 4.47, 95 % CI [2.28, 8.78]), as did inability to stop gambling (OR = 3.18, 95 % CI [2.22, 4.54]). Age was negatively associated with problematic gambling (OR = 0.94, 95 % CI [0.91, 0.97]).</div></div><div><h3>Conclusions</h3><div>Findings reveal high rates of problematic gambling amongst cryptocurrency traders, with distinct motivational and cognitive predictors at different risk levels. Results suggest the need for targeted educational programmes and intervention strategies tailored to address specific risk factors.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"244 ","pages":"Article 105741"},"PeriodicalIF":3.9,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI and omics technologies in biobanking: Applications and challenges for public health","authors":"Pedro Venturini ,&nbsp;Paula Lobato Faria ,&nbsp;João V. Cordeiro","doi":"10.1016/j.puhe.2025.105726","DOIUrl":"10.1016/j.puhe.2025.105726","url":null,"abstract":"<div><h3>Objectives</h3><div>Considering the growing intersection of biobanks, artificial intelligence (AI) and omics research, and their critical impact on public health, this study aimed to explore the current and future public health implications and challenges of AI and omics-driven innovations in biobanking.</div></div><div><h3>Study design</h3><div>Narrative literature review.</div></div><div><h3>Methods</h3><div>A structured literature search was conducted in Scopus, PubMed, Web of Science and IEEExplore databases using relevant search terms. Additional references were identified through backward and forward citation chaining. Key themes were aggregated and analysed through thematic analysis.</div></div><div><h3>Results</h3><div>Thirty-seven studies were selected for analysis, leading to the identification and categorisation of key developments. Several key technical, ethical and implementation challenges were also identified, including AI model selection, data accessibility, variability and quality issues, lack of robust and standardised validation methods, explainability, accountability, lack of transparency, algorithmic bias, privacy, security and fairness issues, and governance model selection. Based on these results, potential future scenarios of AI and omics integration in biobanking and their related public health implications were considered.</div></div><div><h3>Conclusions</h3><div>While AI and omics-driven innovations in biobanking offer specific transformative public health benefits, addressing their technical, ethical and implementation challenges is crucial. Robust regulatory frameworks, feasible governance models, access to quality data, interdisciplinary collaboration, and transparent and validated AI systems are essential to maximise benefits and mitigate risks. Further research and policy development are needed to support the responsible integration of these technologies in biobanking and public health.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"243 ","pages":"Article 105726"},"PeriodicalIF":3.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143892278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy loss <28 weeks gestation in maternal influenza and COVID-19 vaccination studies: a review of data sources, 2009–2024","authors":"Alexa Dakiniewich,&nbsp;Sarah Graham,&nbsp;Amalie Dyda,&nbsp;Lisa McHugh","doi":"10.1016/j.puhe.2025.105733","DOIUrl":"10.1016/j.puhe.2025.105733","url":null,"abstract":"<div><h3>Objectives</h3><div>To address gaps in maternal vaccination and pregnancy loss research, large, complex datasets are needed. We aimed to identify and evaluate data sources and data collection methods currently used to capture pregnancy losses &lt;28 weeks following maternal influenza and COVID-19 vaccination research.</div></div><div><h3>Study design</h3><div>Narrative Review.</div></div><div><h3>Methods</h3><div>PubMed, CINAHL, Scopus, and Web of Science were used to identify studies that investigated pregnancy loss &lt;28 gestational weeks following influenza and COVID-19 vaccinations from January 1st^, 2009, to March 19th^, 2024. Within the resulting studies, the data source(s) used to capture exposure and outcome data were identified and categorised. The capacity to capture and measure exposures, outcomes, and missing data within categories was investigated.</div></div><div><h3>Results</h3><div>28 articles met the inclusion criteria, representing 1,113,878 participants. Most articles (n = 19) used multiple data sources within the one study, often obtaining exposure and outcome data from separate data sources. Categories of data sources included: registries, adverse reporting systems, medical records, and survey or interview methods.</div></div><div><h3>Conclusion</h3><div>Current data collection practices and existing data sources are adversely impacting data quality, and the ability to combine large datasets necessary for analysing early pregnancy loss risk factors. This also hinders our ability to evaluate the safety of early maternal vaccination and subsequent miscarriage. Establishing pregnancy loss registries using standardised data collection and coding practices, consistent terminology, and accurate exposure and outcome timing is critical. In the absence of registries, we propose an alternative source to capture both pregnancy loss and maternal vaccination data.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"243 ","pages":"Article 105733"},"PeriodicalIF":3.9,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143882386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlates of the sexual and reproductive health service utilization among older people living with HIV in China: Findings from the sexual well-being (SWELL) Study","authors":"Xin Peng ,&nbsp;Xinyi Li ,&nbsp;Bingyi Wang ,&nbsp;Ying Wang ,&nbsp;Peng Xu ,&nbsp;Yong Lu ,&nbsp;Bingyu Liang ,&nbsp;Lin Ouyang ,&nbsp;Guohui Wu ,&nbsp;Maohe Yu ,&nbsp;Jiewei Liu ,&nbsp;Xiaopei Shen ,&nbsp;Xiaojun Meng ,&nbsp;Siyang Liu ,&nbsp;Yong Cai ,&nbsp;Huachun Zou","doi":"10.1016/j.puhe.2025.105729","DOIUrl":"10.1016/j.puhe.2025.105729","url":null,"abstract":"<div><h3>Objectives</h3><div>Sexual and reproductive health (SRH) is vital to personal overall well-being, this study aims to explore the SRH service utilization and its correlates among older people living with HIV (PLHIV) in China.</div></div><div><h3>Study design</h3><div>Cross-sectional study.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional study to collect data from older PLHIV aged 50 and above in HIV/AIDS treatment hospitals in China. SRH services included reproductive health examination, STI testing, sexual life counseling, and cervical cancer screening. Multivariable logistic regression models were used to analyze the correlates of SRH service utilization (four dichotomous outcome variables).</div></div><div><h3>Results</h3><div>680 older PLHIV (500 males and 180 females) were enrolled. The mean age was 60.3 ± 7.8 years. 18.2 % of participants received a reproductive health examination, 9.0 % received STI testing, 36.1 % sought sexual life counseling, and 36.1 % of females had screened for cervical cancer. Females (aOR = 3.26, 95 %CI: 1.89–5.60), those with higher education (2.15, 1.11–4.15), higher income (2.08, 1.24–3.50), and a physical health condition (2.11, 1.14–3.90) were more likely to have received a reproductive health examination. Individuals who were employed (2.05, 1.05–3.97), had a physical health condition (2.91, 1.39–6.00), identified as homosexual (2.17, 1.06–4.47), or reported sexual desire (2.14, 1.01–4.66) were more likely to have received STI testing Living in urban areas (4.33,1.89–9.92), higher education (3.71, 1.20–11.45), depression (4.13, 1.82–9.37), bisexual orientation (2.80, 1.23–6.36), and sexual satisfaction (2.64, 1.22–5.72) were positively significantly associated with seeking sexual life counseling. Those with higher education (5.79, 2.00–16.70), higher income (3.98, 1.24–12.76), and a physical health condition (13.91, 2.89–66.92) were more likely to have screened for cervical cancer.</div></div><div><h3>Conclusion</h3><div>Improving the SRH messages and services tailored for older PLHIV may be conducive to improving their utilization of SRH services.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"243 ","pages":"Article 105729"},"PeriodicalIF":3.9,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143882387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pandemic preparedness and response priorities in Latin America: A regional Delphi consensus.","authors":"César Arturo Méndez Lizárraga, Ruben Armas-González, Steev Loyola, Alfredo Bruno, Victoria Pando-Robles, Julián Alfredo Fernández-Niño, Reynaldo Flores Muñoz, Josefina Coloma, Andrés G Lescano, Enrique Bravo-García, Patricia J García, Juan Garza, Esbeydy Pardo, Susie Welty, Michael J A Reid, Jaime Sepúlveda","doi":"10.1016/j.puhe.2025.01.003","DOIUrl":"https://doi.org/10.1016/j.puhe.2025.01.003","url":null,"abstract":"<p><strong>Objective: </strong>The Independent Panel for Pandemic Preparedness and Response issued a series of recommendations for future pandemic preparedness and response. Latin America's COVID-19-related deaths represented 25 % of the global demises, despite harboring less than 8 % of the world's population. As little data exists to support whether the Panel's recommendations reflect public health professionals' priorities in the region the study aimed to define these priorities utilizing a Delphi study.</p><p><strong>Study design: </strong>A consensus-building modified Delphi technique.</p><p><strong>Methods: </strong>For the first two rounds, participants were asked to rank a list of topics across seven domains on a 4-point Likert scale. Topics voted by at least 75 % of participants in either round as very important were included in the final round. Participants ranked the topics from each of the seven domains in numeric order to define top priorities.</p><p><strong>Results: </strong>A total of 115 responses were obtained across three rounds. Most respondents were involved in direct efforts against COVID-19 (75·0-86·%) and a considerable proportion had more than 16 years of public health experience (37·3-50·0 %). The top priority issues were zoonotic disease-pathogen surveillance systems (27·4 points), robust infection and prevention control programs (22·8 points), and indicator and event-based monitoring and reporting systems (22·1 points).</p><p><strong>Conclusions: </strong>Establishing priorities for future pandemics is critical to ensure better health outcomes. The region should strengthen collaboration and enhance its capacities while conducting country-level analysis and defining priorities for future arrangements.</p>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":" ","pages":"105602"},"PeriodicalIF":3.9,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Individual and joint associations of socioeconomic inequalities and unhealthy lifestyle with incident gastric cancer: A prospective cohort study","authors":"Xiang Wang ,&nbsp;Shangxin Zhang ,&nbsp;Yuqiang Zhao ,&nbsp;Shiyin Meng ,&nbsp;Jing Wang ,&nbsp;Zhuoyi Wu ,&nbsp;Jing Ni","doi":"10.1016/j.puhe.2025.105730","DOIUrl":"10.1016/j.puhe.2025.105730","url":null,"abstract":"<div><h3>Objectives</h3><div>Gastric cancer (GC) remains a significant public health challenge, with accumulating evidence indicating an association between socioeconomic status (SES) and GC risk. This study aimed to examine the independent and synergistic effects of SES and lifestyle on GC incidence within a large prospective cohort.</div></div><div><h3>Study design</h3><div>Prospective cohort study.</div></div><div><h3>Methods</h3><div>Data were analysed from 349,908 UK Biobank participants using latent class analysis to determine SES (household income, education, employment). Lifestyle was assessed based on smoking status, alcohol consumption, physical activity, body mass index and diet. Multivariable Cox regression tested associations between SES, lifestyle and GC, with mediation and interaction analyses used to explore their relationships.</div></div><div><h3>Results</h3><div>SES was significantly associated with GC risk (hazard ratio [HR] = 1.35, 95 % confidence interval [CI], 1.20–1.52). An unhealthy lifestyle was also linked to increased GC risk (HR = 1.48, 95 % CI, 1.30–1.68). Individuals with low SES and an unhealthy lifestyle had a 195 % higher risk of GC compared to those with high SES and a healthy lifestyle (HR = 2.95, 95 % CI, 2.11–4.11). Mediation analysis indicated that 5.26 % of the SES-GC risk association was mediated by lifestyle factors. No significant interaction between SES and lifestyle was observed.</div></div><div><h3>Conclusions</h3><div>Low SES was related to an increased risk of GC, some of which may be mediated by unhealthy lifestyle. Public health initiatives should focus on addressing socioeconomic disparities and improving lifestyle factors to reduce GC incidence.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"243 ","pages":"Article 105730"},"PeriodicalIF":3.9,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}