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Seminars in Diagnostic Pathology最新文献

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EDITORIAL BOARD (p/u from previous issue) 编辑委员会（上期增刊）
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2024-11-01 DOI: 10.1053/S0740-2570(24)00095-9
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引用次数: 0
TABLE OF CONTENTS (p/u from previous issue w/updates) 目 录（上期内容，有更新）
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2024-11-01 DOI: 10.1053/S0740-2570(24)00096-0
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引用次数: 0
"Lobular lesions of the breast: From the classic to the variants" "乳腺小叶病变：从经典到变异"。
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2024-11-01 DOI: 10.1053/j.semdp.2024.10.002
Erinn Downs , H. Evin Gulbahce
{"title":"\"Lobular lesions of the breast: From the classic to the variants\"","authors":"Erinn Downs ,&nbsp;H. Evin Gulbahce","doi":"10.1053/j.semdp.2024.10.002","DOIUrl":"10.1053/j.semdp.2024.10.002","url":null,"abstract":"<div><div>The aim of this review is to provide the surgical pathologist an overview of lobular lesions, from <em>in situ</em> to invasive carcinoma and the variants, by discussing the epidemiology, clinical characteristics, morphology, immunohistochemistry, known molecular data as well as the treatment recommendations. The recognition of histologic variants of both <em>in situ</em> and invasive lobular carcinoma has expanded the differential diagnosis. Awareness of these different entities is important as treatment recommendations continue to evolve.</div></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"41 6","pages":"Pages 258-271"},"PeriodicalIF":2.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraoperative evaluation of surgical margins in breast cancer 乳腺癌手术边缘的术中评估。
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2024-11-01 DOI: 10.1053/j.semdp.2024.06.005
Lauren Kopicky , Betty Fan , Stephanie A. Valente
{"title":"Intraoperative evaluation of surgical margins in breast cancer","authors":"Lauren Kopicky ,&nbsp;Betty Fan ,&nbsp;Stephanie A. Valente","doi":"10.1053/j.semdp.2024.06.005","DOIUrl":"10.1053/j.semdp.2024.06.005","url":null,"abstract":"<div><div>Achieving clear resection margins at the time of lumpectomy is essential for optimal patient outcomes. Margin status is traditionally determined by pathologic evaluation of the specimen and often is difficult or impossible for the surgeon to definitively know at the time of surgery, resulting in the need for re-operation to obtain clear surgical margins. Numerous techniques have been investigated to enhance the accuracy of intraoperative margin and are reviewed in this manuscript.</div></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"41 6","pages":"Pages 293-300"},"PeriodicalIF":2.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141535748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVER (PMS 180&K) (p/u from previous issue w/updates) 封面（PMS 180&K）（上一期的原版，有更新）
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2024-11-01 DOI: 10.1053/S0740-2570(24)00093-5
{"title":"COVER (PMS 180&K) (p/u from previous issue w/updates)","authors":"","doi":"10.1053/S0740-2570(24)00093-5","DOIUrl":"10.1053/S0740-2570(24)00093-5","url":null,"abstract":"","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"41 6","pages":"Page OFC"},"PeriodicalIF":2.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142654953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spectrum of atypical ductal hyperplasia (ADH) and ductal carcinoma in-situ (DCIS): Diagnostic challenges 非典型导管增生（ADH）和导管原位癌（DCIS）的谱系：诊断难题。
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2024-11-01 DOI: 10.1053/j.semdp.2024.09.001
Philip Bomeisl , Hannah Gilmore
{"title":"Spectrum of atypical ductal hyperplasia (ADH) and ductal carcinoma in-situ (DCIS): Diagnostic challenges","authors":"Philip Bomeisl ,&nbsp;Hannah Gilmore","doi":"10.1053/j.semdp.2024.09.001","DOIUrl":"10.1053/j.semdp.2024.09.001","url":null,"abstract":"<div><div>Breast specimens are some of the more common specimens sent to the pathology laboratory for diagnosis. From a clinical perspective, the diagnoses fall into three broad categories: benign, atypical and malignant with patients then being managed according to established guidelines. However, the pathologic diagnosis can sometimes be challenging, and the distinction between these categories is sometimes far more subtle and subjective than non-pathologist may understand. One recurring diagnostic challenge in breast pathology is the diagnosis of atypical ductal hyperplasia (ADH) versus ductal carcinoma in situ (DCIS). While many cases are straightforward, others are quite borderline and challenging to classify consistently with significant interobserver variation amongst pathologists. The distinction between ADH and DCIS is critical from a clinical management perspective because one is treated as a risk factor, and the other as a malignancy that will be completely surgically excised and may require radiation therapy. This review will address the spectrum of ADH and DCIS with the associated diagnostic challenges in the real-world setting from presentation at core needle biopsy to surgery.</div></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"41 6","pages":"Pages 252-257"},"PeriodicalIF":2.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142267060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Goblet cell adenocarcinoma 上皮细胞腺癌
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2024-09-01 DOI: 10.1053/j.semdp.2024.08.003
Jula Veerapong, Mojgan Hosseini
{"title":"Goblet cell adenocarcinoma","authors":"Jula Veerapong,&nbsp;Mojgan Hosseini","doi":"10.1053/j.semdp.2024.08.003","DOIUrl":"10.1053/j.semdp.2024.08.003","url":null,"abstract":"<div><p>Appendix, considered a vestigial and disposable organ, has been long neglected as a source of abdominal tumors. Among the appendiceal tumors, goblet cell adenocarcinoma (GCA) is a rare primary epithelial neoplasm which has undergone multiple name changes and classifications in recent years, adding to confusion surrounding this unique amphicrine tumor. This entity was previously known as goblet cell carcinoid and adenocarcinoma ex goblet cell carcinoid. This review article provides an update on pathology, nomenclature, and recent classification systems with emphasis on 2019 World Health Organization Classification of Tumors, 3-tiered grading system.<span><span><sup>1</sup></span></span></p></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"41 5","pages":"Pages 230-234"},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Appendiceal adenocarcinoma: Current concepts & challenges 阑尾腺癌：当前的概念与挑战。
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2024-09-01 DOI: 10.1053/j.semdp.2024.08.005
Phoenix D. Bell
{"title":"Appendiceal adenocarcinoma: Current concepts & challenges","authors":"Phoenix D. Bell","doi":"10.1053/j.semdp.2024.08.005","DOIUrl":"10.1053/j.semdp.2024.08.005","url":null,"abstract":"<div><p>Appendiceal adenocarcinoma (ApAC) is a rare malignancy, comprising less than 1 % of all gastrointestinal tumors. The current World Health Organization classifies ApAC as mucinous or nonmucinous. Mucinous ApAC are composed of pools of mucin lined by cells with low- and high-grade cytology and areas of infiltrative invasion. Nonmucinous ApAC histologically resemble conventional colorectal adenocarcinomas and have a worse prognosis than their mucinous counterpart. Unfortunately, the nomenclature and histologic classification of ApAC, specifically the mucinous subtype, has changed several times throughout the years, contributing to diagnostic confusion for pathologists. The treatment for mucinous ApAC differs from that of other appendiceal mucinous neoplasms, thus accurate diagnosis is key to patient management and outcome. This review discusses the current classification and staging of ApAC with a particular emphasis on the mucinous subtype and peritoneal disease, as these areas are the most challenging for practicing surgical pathologists.</p></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"41 5","pages":"Pages 213-221"},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0740257024000704/pdfft?md5=39f03b1d3dfa4cae71f84dc71896b7ce&pid=1-s2.0-S0740257024000704-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MASTHEAD (p/u from previous issue) MASTHEAD （P/U 自上期起）
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2024-09-01 DOI: 10.1053/S0740-2570(24)00074-1
{"title":"MASTHEAD (p/u from previous issue)","authors":"","doi":"10.1053/S0740-2570(24)00074-1","DOIUrl":"10.1053/S0740-2570(24)00074-1","url":null,"abstract":"","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"41 5","pages":"Page IFC"},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142135771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A practical guide to serrated appendiceal lesions 阑尾锯齿状病变实用指南
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2024-09-01 DOI: 10.1053/j.semdp.2024.07.001
Domenika Ortiz Requena, Rhonda K. Yantiss
{"title":"A practical guide to serrated appendiceal lesions","authors":"Domenika Ortiz Requena,&nbsp;Rhonda K. Yantiss","doi":"10.1053/j.semdp.2024.07.001","DOIUrl":"10.1053/j.semdp.2024.07.001","url":null,"abstract":"<div><p>Several neoplastic and non-neoplastic proliferations of the appendix can show varying degrees of serrated epithelial architecture. Of these, diffuse mucosal hyperplasia is most common, followed in frequency by low-grade mucinous and serrated neoplasms. It is important to distinguish serrated appendiceal neoplasms from their potential mimics because these entities may be managed differently. Diffuse mucosal hyperplasia is a non-neoplastic change that usually develops in the setting of resolving appendicitis and requires no further therapy or surveillance, and serrated neoplasms confined to the mucosa are adequately treated by appendectomy alone. On the other hand, low-grade appendiceal mucinous neoplasms may require surveillance, and those with extra-appendiceal spread differ from adenocarcinomas arising from serrated neoplasms with respect to both treatment and prognosis. Low-grade mucinous neoplasms in the peritoneum are frequently amenable to peritoneum-directed therapies alone, while adenocarcinomas derived from serrated neoplasms often spread to both regional lymph nodes and the peritoneum, potentially requiring right colectomy and systemic chemotherapy. The purpose of this review is to summarize the literature regarding the clinical and pathologic features of appendiceal lesions that show epithelial serration and provide the reader with helpful tips to distinguish serrated neoplasms from their mimics.</p></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"41 5","pages":"Pages 243-249"},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141704060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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