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Seminars in Diagnostic Pathology最新文献

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The history of the microscope reflects advances in science and medicine 显微镜的历史反映了科学和医学的进步
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2025-03-01 DOI: 10.1053/j.semdp.2024.01.002
Caitlin A. Noble , Andrew P. Biesemier , Sarah F. McClees , Aljunaid M. Alhussain , Stephen E. Helms , Robert T. Brodell
{"title":"The history of the microscope reflects advances in science and medicine","authors":"Caitlin A. Noble ,&nbsp;Andrew P. Biesemier ,&nbsp;Sarah F. McClees ,&nbsp;Aljunaid M. Alhussain ,&nbsp;Stephen E. Helms ,&nbsp;Robert T. Brodell","doi":"10.1053/j.semdp.2024.01.002","DOIUrl":"10.1053/j.semdp.2024.01.002","url":null,"abstract":"<div><div>Microscopes, more than any other instrument, reflect advances in clinical medicine over the past several hundred years. As the primary tool of the pathologist, they were, and continue to be, a key connector between the bedside and basic sciences. One specific example is the science of clinical dermatology, which relies on clinical-pathologic correlation to make a definitive diagnosis. The microscopes used by pathologists, however, are more than scientific artifacts. Many antique microscopes are hand-crafted works of art. Even while recognizing that light microscopes may soon be obsolete as scanned slides and computer joy-sticks replace optical instruments in patient care and teaching, their significance will not be diminished. The microscope will never be forgotten in the history, art, and science of medicine, for these instruments set the social and cultural stage for modern, scientific patient care.</div></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"42 2","pages":"Article 150831"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139460334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mark Wick contributions to pathology of the mediastinum 马克-维克对纵隔病理学的贡献
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2025-03-01 DOI: 10.1053/j.semdp.2024.01.006
Horacio Maluf
{"title":"Mark Wick contributions to pathology of the mediastinum","authors":"Horacio Maluf","doi":"10.1053/j.semdp.2024.01.006","DOIUrl":"10.1053/j.semdp.2024.01.006","url":null,"abstract":"<div><div><span><span><span>Mark Wick made a wide range of contributions to the field of mediastinal pathology. Early papers amplified the spectrum of neuroendocrine carcinomas<span><span> of the thymus and brought attention to the aggressive nature of this tumor, also highlighting the occurrence of coexisting </span>carcinoid tumor and </span></span>small cell carcinoma<span> of this organ. The controversial issue of thymoma<span> classification was addressed in several papers and editorial comments, while also reporting a case of metastatic thymoma. A series of thymic carcinomas<span> as well a report on the unusual clear cell variant bear his name as one of the authors. He summarized the topic of mediastinal cyst in a review published in 2005. </span></span></span></span>Sarcomas arising in </span>mediastinal germ cell tumors<span> were also within the purview of his interests, with a publication of series of seven cases. He reviewed the topic of inflammatory myofibroblastic tumor of the heart and added a case to the existing literature. Two books dedicated to different aspect of mediastinal pathology also carry his name in the front cover in association with Drs Taazelar in one and Marchevsky in the other.</span></div></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"42 2","pages":"Article 150835"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139373855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical-pathologic correlation: The impact of grossing at the bedside 临床与病理相关性：床旁大体检查的影响
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2025-03-01 DOI: 10.1053/j.semdp.2024.01.007
C. Alexis Noble , Chinmoy Bhate , Buu T. Duong , Allison R. Cruse , Robert T. Brodell , Riley C. Hanus
{"title":"Clinical-pathologic correlation: The impact of grossing at the bedside","authors":"C. Alexis Noble ,&nbsp;Chinmoy Bhate ,&nbsp;Buu T. Duong ,&nbsp;Allison R. Cruse ,&nbsp;Robert T. Brodell ,&nbsp;Riley C. Hanus","doi":"10.1053/j.semdp.2024.01.007","DOIUrl":"10.1053/j.semdp.2024.01.007","url":null,"abstract":"<div><div><span>The unenlightened clinician may submit a skin specimen to the lab and expect an “answer.” The experienced clinician knows that in performing skin biopsies, it is critical to select the most appropriate: 1) anatomic location for the biopsy</span><span><span><sup>1</sup></span></span><sup>,</sup><span><span><sup>2</sup></span></span>; 2) type of biopsy<span><span><sup>1</sup></span></span><sup>,</sup><span><span><sup>2</sup></span></span><span><span>; 3) depth and breadth of the biopsy; and 4) medium for hematoxylin and </span>eosin<span> staining (formalin) or direct immunofluorescence (Michel's Transport Medium or normal saline).</span></span><span><span><sup>2</sup></span></span> Demographic information, anatomic location, clinical context, and differential diagnosis are all critical components of a properly completed requisition form.<span><span>3</span></span>, <span><span>4</span></span>, <span><span>5</span></span><span> Proper biopsy design and appropriate grossing of the tissue at the bedside should be added to this list. In this article, we review the basics of gross pathologic examination and then provide four examples to demonstrate that optimal clinical-pathologic correlation requires the clinician consider the needs of the pathologist when tissue is presented to the lab.</span></div></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"42 2","pages":"Article 150836"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139373870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EDITORIAL BOARD (p/u from previous issue) 编辑委员会（上期增刊）
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2025-03-01 DOI: 10.1053/S0740-2570(25)00022-X
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引用次数: 0
Targetoid hemosiderotic hemangioma: A review article 靶形血蜘蛛网状血管瘤：综述文章。
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2025-03-01 DOI: 10.1053/j.semdp.2024.11.002
Toan Bui , Laura M. Rezac , C. Alexis Noble , Ariel R. Velasquez-Evers , Robert T. Brodell
{"title":"Targetoid hemosiderotic hemangioma: A review article","authors":"Toan Bui ,&nbsp;Laura M. Rezac ,&nbsp;C. Alexis Noble ,&nbsp;Ariel R. Velasquez-Evers ,&nbsp;Robert T. Brodell","doi":"10.1053/j.semdp.2024.11.002","DOIUrl":"10.1053/j.semdp.2024.11.002","url":null,"abstract":"<div><h3>Background</h3><div>Targetoid hemosiderotic hemangioma (THH), also known as hobnail lymphatic malformation (HLL) or hobnail hemangioma, is an uncommon, acquired vascular lesion with a dynamic presentation and an unclear etiology. It predominantly affects adults with an age range from 9 to 78 years and has no gender predilection. The lesion is thought to arise from trauma, leading to micro-shunts between small lesional capillaries and adjacent lymphatic vessels.</div></div><div><h3>Methods</h3><div>This review article examines the clinical, histologic, and immunohistochemical characteristics of THH, and explores its differential diagnoses, including Kaposi's sarcoma, solitary angiokeratoma, retiform hemangioendothelioma, and Dabska tumor.</div></div><div><h3>Results</h3><div>THH presents clinically as asymptomatic, well-circumscribed lesions with a central red-blue and/or brown papule surrounded by a peripheral ecchymotic ring, giving a \"bull's-eye\" or targetoid appearance. Histologically, THH exhibits dilated vascular channels lined by hobnail endothelial cells, red blood cell extravasation, hemosiderin deposition, and mild lymphohistiocytic infiltrates. Immunohistochemistry is positive for D2-40, a lymphatic endothelial marker.</div></div><div><h3>Conclusions</h3><div>Heightened awareness of the clinical appearance of these solitary targetoid lesions is important. Without clinical-pathologic correlation, the branching telangiectatic vessels and purpura seen in THH could suggest more concerning vascular lesions like Kaposi sarcoma.</div></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"42 2","pages":"Article 150869"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MASTHEAD (p/u from previous issue) MASTHEAD （P/U 自上期起）
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2025-03-01 DOI: 10.1053/S0740-2570(25)00021-8
{"title":"MASTHEAD (p/u from previous issue)","authors":"","doi":"10.1053/S0740-2570(25)00021-8","DOIUrl":"10.1053/S0740-2570(25)00021-8","url":null,"abstract":"","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"42 2","pages":"Article 150885"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TABLE OF CONTENTS (p/u from previous issue w/updates) 目 录（上期内容，有更新）
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2025-03-01 DOI: 10.1053/S0740-2570(25)00023-1
{"title":"TABLE OF CONTENTS (p/u from previous issue w/updates)","authors":"","doi":"10.1053/S0740-2570(25)00023-1","DOIUrl":"10.1053/S0740-2570(25)00023-1","url":null,"abstract":"","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"42 2","pages":"Article 150887"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contributions of Dr. Wick to the pathology of diseases of the lung and pleura 维克博士对肺和胸膜疾病病理学的贡献。
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2025-03-01 DOI: 10.1053/j.semdp.2024.01.005
Saul Suster
{"title":"Contributions of Dr. Wick to the pathology of diseases of the lung and pleura","authors":"Saul Suster","doi":"10.1053/j.semdp.2024.01.005","DOIUrl":"10.1053/j.semdp.2024.01.005","url":null,"abstract":"<div><div>The curriculum vitae of Dr. Mark R. Wick contains 57 peer-reviewed publications, 3 editorials, 6 book chapters and a whole book dedicated to diseases of the lung and pleura. It is remarkable that such productivity should represent only a small portion of the overall output of Dr. Wick, which includes (at last count) 341 original peer-review publications, 119 invited review articles, 93 book chapters, 42 editorials, 3 society-related position papers, 18 books and 2 interactive video disks. Yet, his contributions to the literature in pulmonary and pleural pathology have been significant and influential and have established for him a national and international reputation as one of the leading experts in pulmonary pathology. Herein, it is my privilege to recount the various publications contributed by Dr. Wick to this topic, which span the gamut from transplant pathology to neoplastic diseases of the lung and pleura.</div></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"42 2","pages":"Article 150834"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139373856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVER (PMS 180&K) (p/u from previous issue w/updates) 封面（PMS 180&K）（上一期的原版，有更新）
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2025-03-01 DOI: 10.1053/S0740-2570(25)00020-6
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引用次数: 0
Festschrift for Drs. Wick and Santa Cruz 为博士们准备的礼物。威克和圣克鲁斯
IF 2.9 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2025-03-01 DOI: 10.1016/j.semdp.2025.150895
Justin A. Bishop
{"title":"Festschrift for Drs. Wick and Santa Cruz","authors":"Justin A. Bishop","doi":"10.1016/j.semdp.2025.150895","DOIUrl":"10.1016/j.semdp.2025.150895","url":null,"abstract":"","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"42 2","pages":"Article 150895"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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