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Seminars in Diagnostic Pathology最新文献

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Small biopsies in the head and neck: Bone and soft tissue 头颈部小活检：骨和软组织
IF 2.3 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2023-09-01 DOI: 10.1053/j.semdp.2023.06.003
Aarti E Sharma , Darcy A Kerr , Nicole A Cipriani
{"title":"Small biopsies in the head and neck: Bone and soft tissue","authors":"Aarti E Sharma ,&nbsp;Darcy A Kerr ,&nbsp;Nicole A Cipriani","doi":"10.1053/j.semdp.2023.06.003","DOIUrl":"10.1053/j.semdp.2023.06.003","url":null,"abstract":"<div><p><span>Bone and soft tissue lesions in the head and neck encompass not only a broad morphologic spectrum but also significant inherent clinicopathologic overlap. Epidemiology<span><span>, radiology, and location – similar to the diagnostic assessment in other sites – are especially important considerations in the context of an established mesenchymal proliferation. Herein, the approach towards diagnosis is stratified by morphology (spindle, </span>sarcomatoid, epithelioid, round cell), cellular lineage (fibroblastic, </span></span>nerve sheath, rhabdomyogenic), and tumor grade (benign, low- to high-grade malignant) as the basis of further immunohistochemical or molecular investigation.</p></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"40 5","pages":"Pages 353-370"},"PeriodicalIF":2.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10102032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MASTHEAD (p/u from previous issue) MASTHEAD（上一期的p/u）
IF 2.3 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2023-09-01 DOI: 10.1053/S0740-2570(23)00082-5
{"title":"MASTHEAD (p/u from previous issue)","authors":"","doi":"10.1053/S0740-2570(23)00082-5","DOIUrl":"https://doi.org/10.1053/S0740-2570(23)00082-5","url":null,"abstract":"","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"40 5","pages":"Page IFC"},"PeriodicalIF":2.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50189861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salivary gland neoplasms in small biopsies and fine needle aspirations 小活检和细针穿刺中的涎腺肿瘤
IF 2.3 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2023-09-01 DOI: 10.1053/j.semdp.2023.04.010
Jalal B. Jalaly, Zubair W. Baloch
{"title":"Salivary gland neoplasms in small biopsies and fine needle aspirations","authors":"Jalal B. Jalaly,&nbsp;Zubair W. Baloch","doi":"10.1053/j.semdp.2023.04.010","DOIUrl":"10.1053/j.semdp.2023.04.010","url":null,"abstract":"<div><p><span><span>Salivary gland neoplasms are rare and represent a diverse group of </span>head and neck tumors. Their diagnosis in limited cellularity specimens can be challenging as many of these have overlapping clinical, radiological presentation, and pathologic features. </span>Fine needle aspiration and/or core biopsies are more of a norm than rarity to be performed preoperatively to provide invaluable information that can guide clinical management including surgery. Even though these limited specimens may not always provide a definitive diagnosis; they have high sensitivity in confirming primary neoplasia, assessing the tumor grade, and ruling out non-surgical disease. An algorithmic pattern based approach can help narrow the differential diagnosis; leading to a definitive diagnosis with the help of specific ancillary studies.</p></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"40 5","pages":"Pages 340-348"},"PeriodicalIF":2.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10040917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Challenging differential diagnoses in small biopsies from the sinonasal tract 鼻腔小活检的鉴别诊断具有挑战性
IF 2.3 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2023-09-01 DOI: 10.1053/j.semdp.2023.04.011
Anna-Karoline Israel , Vincent Cracolici , Christopher C. Griffith
{"title":"Challenging differential diagnoses in small biopsies from the sinonasal tract","authors":"Anna-Karoline Israel ,&nbsp;Vincent Cracolici ,&nbsp;Christopher C. Griffith","doi":"10.1053/j.semdp.2023.04.011","DOIUrl":"10.1053/j.semdp.2023.04.011","url":null,"abstract":"<div><p><span><span>Sinonasal biopsy specimens are a challenging area in anatomic pathology. The small, often fragmented or crushed nature of these biopsies can hinder morphologic assessment. Additionally, many of the tumors in this area are rare and share morphologic, and sometime immunophenotypic similarities. In many cases, </span>immunohistochemistry<span> is helpful if not necessary to reach a specific diagnosis. In other cases, a specific diagnosis is not possible and a differential diagnosis must be given on a biopsy specimen despite access to a well-equipped immunohistochemistry laboratory. This review article groups some of the more challenging entities in the sinonasal region based on morphologic patterns. These include low grade squamoid lesions such as sinonasal (Schneiderian) papilloma and </span></span><em>DEK</em>::<em>AFF2</em><span> rearranged carcinoma, glandular neoplasms such as intestinal and non-intestinal type sinonasal adenocarcinoma, high-grade carcinomas such as HPV-related multiphenotypic sinonasal carcinoma, NUT carcinoma and SWI/SNF deficient carcinomas, small round blue cell tumors<span> such as teratocarcinosarcoma, neuroendocrine carcinoma<span><span> and olfactory neuroblastoma<span>, and finally, low grade spindle cell<span> neoplasms such as glomangiopericytoma, biphenotypic sinonasal sarcoma and </span></span></span>solitary fibrous tumor.</span></span></span></p></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"40 5","pages":"Pages 321-332"},"PeriodicalIF":2.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10034437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EDITORIAL BOARD (p/u from previous issue) 编辑委员会（上一期的p/u）
IF 2.3 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2023-09-01 DOI: 10.1053/S0740-2570(23)00083-7
{"title":"EDITORIAL BOARD (p/u from previous issue)","authors":"","doi":"10.1053/S0740-2570(23)00083-7","DOIUrl":"https://doi.org/10.1053/S0740-2570(23)00083-7","url":null,"abstract":"","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"40 5","pages":"Page i"},"PeriodicalIF":2.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50169647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVER (PMS 180&K) (p/u from previous issue w/updates) 封面（PMS 180和K）（上一期的p/u，带更新）
IF 2.3 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2023-09-01 DOI: 10.1053/S0740-2570(23)00081-3
{"title":"COVER (PMS 180&K) (p/u from previous issue w/updates)","authors":"","doi":"10.1053/S0740-2570(23)00081-3","DOIUrl":"https://doi.org/10.1053/S0740-2570(23)00081-3","url":null,"abstract":"","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"40 5","pages":"Page OFC"},"PeriodicalIF":2.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50189862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TABLE OF CONTENTS (p/u from previous issue w/updates) 目录（上一期的p/u，带更新）
IF 2.3 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2023-09-01 DOI: 10.1053/S0740-2570(23)00084-9
{"title":"TABLE OF CONTENTS (p/u from previous issue w/updates)","authors":"","doi":"10.1053/S0740-2570(23)00084-9","DOIUrl":"https://doi.org/10.1053/S0740-2570(23)00084-9","url":null,"abstract":"","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"40 5","pages":"Page ii"},"PeriodicalIF":2.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50189863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pearls and pitfalls in the diagnosis of small oral biopsies 口腔小活检诊断中的珍珠和陷阱
IF 2.3 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2023-09-01 DOI: 10.1053/j.semdp.2023.03.001
Kristin K. McNamara, John R. Kalmar
{"title":"Pearls and pitfalls in the diagnosis of small oral biopsies","authors":"Kristin K. McNamara,&nbsp;John R. Kalmar","doi":"10.1053/j.semdp.2023.03.001","DOIUrl":"10.1053/j.semdp.2023.03.001","url":null,"abstract":"<div><p>Pathologic processes affecting the oral and maxillofacial region include a heterogenous group of diseases<span><span><span> with widely variable biologic behaviors. Proper patient management begins with the establishment of an accurate diagnosis, which often relies on histopathologic interpretation of small tissue samples from oral lesions. While confident diagnosis of small </span>oral biopsies can be challenging, an understanding of oral and maxillofacial disease and consistent clinicopathologic correlation can help </span>pathologists<span> recognize inflammatory confounders and overcome common errors in specimen management, including insufficient sample size and non-representative biopsy samples.</span></span></p></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"40 5","pages":"Pages 313-320"},"PeriodicalIF":2.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10101026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Approach to small biopsies in the larynx 喉部小型活检的方法
IF 2.3 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2023-09-01 DOI: 10.1053/j.semdp.2023.06.004
Abberly Lott Limbach
{"title":"Approach to small biopsies in the larynx","authors":"Abberly Lott Limbach","doi":"10.1053/j.semdp.2023.06.004","DOIUrl":"10.1053/j.semdp.2023.06.004","url":null,"abstract":"<div><p><span>Small biopsies in the larynx<span><span> can make a definitive diagnosis challenging due to the sampling or tangential sectioning. The differential diagnosis can be divided into mucosal lesions (squamous papillomas, intraepithelial </span>dysplasia<span>, and invasive squamous cell carcinoma) or submucosal lesions (vocal cord polyps/nodules, amyloidosis, </span></span></span>granular cell tumor<span>, rhabdomyoma<span>, neuroendocrine neoplasms, salivary gland tumors, and cartilaginous tumors). Diagnostic criteria (both morphologic and immunohistochemical) are reviewed to arrive at a diagnosis even on small biopsy.</span></span></p></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"40 5","pages":"Pages 333-339"},"PeriodicalIF":2.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10101567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Indeterminate Thyroid Nodules and Advances in Molecular Pathology 不确定甲状腺结节及其分子病理学研究进展
IF 2.3 3区 医学
Seminars in Diagnostic Pathology Pub Date : 2023-09-01 DOI: 10.1053/j.semdp.2023.05.001
Brendan Belovarac , Fang Zhou , Jake Sharma , Tamar C. Brandler
{"title":"Indeterminate Thyroid Nodules and Advances in Molecular Pathology","authors":"Brendan Belovarac ,&nbsp;Fang Zhou ,&nbsp;Jake Sharma ,&nbsp;Tamar C. Brandler","doi":"10.1053/j.semdp.2023.05.001","DOIUrl":"10.1053/j.semdp.2023.05.001","url":null,"abstract":"<div><p><span>Thyroid </span>cytology<span><span> has in recent years been augmented by molecular testing for indeterminate lesions. Three commercial molecular tests are available which provide variable amounts of detail regarding the genetic alterations identified in a sample. This paper will describe these tests, as well as the common molecular drivers associated with papillary thyroid carcinoma (PTC) and follicular patterned lesions, in order to help the practicing </span>pathologist and clinician better interpret the results of these tests and incorporate this information into their management of cytologically indeterminate thyroid lesions.</span></p></div>","PeriodicalId":49548,"journal":{"name":"Seminars in Diagnostic Pathology","volume":"40 5","pages":"Pages 349-352"},"PeriodicalIF":2.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10399845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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