先天性免疫缺陷患者淋巴细胞增生的个体化治疗方法

IF 2.9 3区医学 Q2 MEDICAL LABORATORY TECHNOLOGY

Seminars in Diagnostic Pathology Pub Date : 2023-11-01 DOI:10.1053/j.semdp.2023.07.001

Shachar Naor , Etai Adam , Ginette Schiby , Dita Gratzinger

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引用次数: 0

摘要

先天性免疫错误(IEI)患者的活检可能会对诊断造成挑战，因为他们的淋巴器官解剖异常，各器官有淋巴增生的趋势，其中一些可能导致恶性淋巴瘤的错误印象，从而可能促使积极的不必要的治疗。在这篇文章中，我们将回顾文献中描述的各种IEI的典型组织学表现，并通过提供说明病例讨论诊断这些患者淋巴细胞增生的适当方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A personalized approach to lymphoproliferations in patients with inborn errors of immunity

Biopsies from patients with inborn error of immunity (IEI) may pose a diagnostic challenge due to the abnormal anatomy of their lymphoid organs and the tendency for the development of lymphoproliferations in various organs, some of which may lead to the wrong impression of malignant lymphoma which may prompt aggressive unnecessary treatment. In this article we will review typical histologic findings in various IEI's described in the literature and discuss the appropriate approach to the diagnosis of lymphoproliferations in these patients by presenting illustrative cases.

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来源期刊

Seminars in Diagnostic Pathology 医学-病理学

CiteScore

4.80

自引率

0.00%

发文量

审稿时长

71 days

期刊介绍： Each issue of Seminars in Diagnostic Pathology offers current, authoritative reviews of topics in diagnostic anatomic pathology. The Seminars is of interest to pathologists, clinical investigators and physicians in practice.