炎性横纹肌母细胞瘤：综述与最新进展

IF 2.9 3区医学 Q2 MEDICAL LABORATORY TECHNOLOGY

Seminars in Diagnostic Pathology Pub Date : 2025-05-20 DOI:10.1016/j.semdp.2025.150917

Andrew L. Folpe

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引用次数: 0

摘要

炎性横纹肌母细胞瘤（IRMT），临床病理和遗传上不同的交界性恶性骨骼肌肿瘤。这些罕见的肿瘤最初被认为是“炎性平滑肌肉瘤”，也有报道称是“富含组织细胞的横纹肌母细胞瘤”和“低级别炎性肌源性肿瘤”。IRMT除了是唯一的交界性恶性骨骼肌肿瘤外，也很少发展为完全恶性的横纹肌肉瘤。本文综述了IRMT和由IRMT引起的横纹肌肉瘤的临床病理、免疫组织化学和分子遗传学特征。

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Inflammatory rhabdomyoblastic tumor: A review and update

Inflammatory rhabdomyoblastic tumors (IRMT), clinicopathologically and genetically distinct skeletal muscle tumors of borderline malignancy. These rare tumors were originally believed to represent “inflammatory leiomyosarcomas” and have also been reported as “histiocyte-rich rhabdomyoblastic tumor” and “low-grade inflammatory myogenic tumor”. In addition to representing the only skeletal muscle tumor of borderline malignancy, IRMT may also rarely progress to fully malignant rhabdomyosarcoma. The clinicopathologic, immunohistochemical and molecular genetic features of IRMT and rhabdomyosarcomas arising from IRMT are reviewed.

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来源期刊

Seminars in Diagnostic Pathology 医学-病理学

CiteScore

4.80

自引率

0.00%

发文量

审稿时长

71 days

期刊介绍： Each issue of Seminars in Diagnostic Pathology offers current, authoritative reviews of topics in diagnostic anatomic pathology. The Seminars is of interest to pathologists, clinical investigators and physicians in practice.