Undersea and Hyperbaric Medicine最新文献_第8页

Jin

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.1007/978-3-540-72816-0_12087

Yin Chang, Qianyu Han, Xiao-chen Bao, Mingdong Wang, Yuxiang Jin, Siang Zhang, Xuewei Zhao, Yiqun Fang, L. Xue

引用次数: 0

Hyperbaric oxygen combined with hydrogen-rich saline protect against acute lung in rat model 高压氧联合富氢盐水对大鼠急性肺模型的保护作用

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.22462/01.01.2023.5

Yin Chang, Qianyu Han, Xiao-chen Bao, Mingdong Wang, Yuxiang Jin, Siang Zhang, Xuewei Zhao, Yi-qun Fang, L. Xue

{"title":"Hyperbaric oxygen combined with hydrogen-rich saline protect against acute lung in rat model","authors":"Yin Chang, Qianyu Han, Xiao-chen Bao, Mingdong Wang, Yuxiang Jin, Siang Zhang, Xuewei Zhao, Yi-qun Fang, L. Xue","doi":"10.22462/01.01.2023.5","DOIUrl":"https://doi.org/10.22462/01.01.2023.5","url":null,"abstract":"Background: To investigate therapeutic effects of hydrogen-rich saline (HRS) combined with hyperbaric oxygen (HBO2) in an experimental rat model of acute lung injury (ALI). Methods: 40 Male Sprague-Dawley rats were randomly divided into sham, LPS, LPS + HBO2, LPS + HRS and LPS + HBO2 + HRS groups. ALI was induced by an intratracheal injection of LPS, then the rats were respectively given single agent treatment of HBO2 or HRS or HBO2 + HRS treatment. The treatments were continued for three days in an experimental rat model of ALI. At the end of the experiment, the lung pathological, inflammatory factors, and cell apoptosis in the pulmonary tissue were detected by Tunel method and cell apoptosis rate was calculated accordingly. Results: In the groups treated with HBO2 + HRS, pulmonary pathological data, wet-dry weight ratio and inflammatory factors of pulmonary tissues and aveolar lavage fluid were signficantly superiror to those of the sham group (p<0.05). Cell apoptosis detection revealed that no matter single agent treatment of HRS or HBO2, or combination treatment, could all alleviate cell apoptosis, and HRS combined with HBO2 treatment was obviously superior to single treatment (p<0.05). Conclusions: HRS or HBO2 single treatment could decrease inflammatory cytokines release in lung tissue, reduce accumulation of oxidative products and alleviate apoptosis of pulmoanry cells, then lead to positive therapeutic effects on ALI induced by LPS. Furthermore, HBO2 combined with HRS treatment presented a synergy effect on cell apoptosis decrease, and a declined trend in inflammatory cytokines release and related inflammatory products generation, compared with single treatment.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72611062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of hyperbaric oxygen after microtia reconstruction using costal cartilage: A retrospective case-control study 用肋软骨重建小体缺损后高压氧的疗效:回顾性病例对照研究

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.22462/01.01.2023.46

N. Murao, A. Oyama, Yuhei Yamamoto, E. Funayama, K. Ishikawa, T. Maeda

{"title":"Efficacy of hyperbaric oxygen after microtia reconstruction using costal cartilage: A retrospective case-control study","authors":"N. Murao, A. Oyama, Yuhei Yamamoto, E. Funayama, K. Ishikawa, T. Maeda","doi":"10.22462/01.01.2023.46","DOIUrl":"https://doi.org/10.22462/01.01.2023.46","url":null,"abstract":"Introduction: Microtia reconstruction with autologous costal cartilage framework grafting is challenging because the three-dimensional structure of the ear is highly complex, and meeting the high aesthetic demands of patients can be difficult. If the skin flap overlying the framework is thinned to achieve a smooth and accentuated outline, a poor blood supply in the thin skin flap may lead to skin necrosis, exposure of the framework, and poor surgical results. Hyperbaric oxygen (HBO2) therapy can promote the healing of complex wounds and flaps. This study sought to determine the effectiveness of HBO2 therapy for prevention of postoperative complications after framework grafting in microtia reconstruction. Methods: We retrospectively evaluated postoperative complications and compared outcomes in pediatric patients who underwent costal cartilage grafting for microtia reconstruction at our institution between 2011 and 2015 according to whether or not they received postoperative HBO2 therapy. HBO2 therapy was applied once daily for a total of 10 sessions starting on the first postoperative day. Results: During the study period, eight patients received HBO2 therapy after costal cartilage grafting and 12 did not. There was no significant difference in the incidence of postoperative ulcers. However, the incidence of framework exposure was lower and the healing time was shorter in patients who received HBO2 therapy than in those who did not. Discussion: HBO2 therapy can be used safely in pediatric patients to reduce postoperative complications and improve the aesthetic outcome of microtia reconstruction. After costal cartilage grafting, HBO2 therapy should be considered as adjuvant therapy.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82014868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of the cardiovascular effects of hyperbaric oxygen therapy in diabetic patients 糖尿病患者高压氧治疗对心血管的影响分析

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.22462/01.01.2023.6

K. Canarslan-Demir, Kubra Ozgok-Kangal, Ayse SAATCI-YASAR, M. A. Erdol, B. Koç

{"title":"Analysis of the cardiovascular effects of hyperbaric oxygen therapy in diabetic patients","authors":"K. Canarslan-Demir, Kubra Ozgok-Kangal, Ayse SAATCI-YASAR, M. A. Erdol, B. Koç","doi":"10.22462/01.01.2023.6","DOIUrl":"https://doi.org/10.22462/01.01.2023.6","url":null,"abstract":"During hyperbaric oxygen (HBO2) therapy in humans there are changes in cardiovascular physiology due to high pressure and hyperoxygenation. Peripheral vasoconstriction, bradycardia and a decrease in cardiac output are observed during HBO2 therapy. These physiological effects of HBO2 therapy on the cardiovascular system are tolerated in healthy people. However, patients with underlying cardiac disease may experience severe problems during HBO2 therapy, such as pulmonary edema and death. Cardiac complications may occur in patients with diabetes mellitus (DM). Therefore, HBO2 therapy may have negative effects on cardiovascular physiology in patients with DM. The present study aimed to examine the cardiovascular effects of HBO2 therapy in diabetic patients. The findings of NT-ProBNP, troponin I, electrocardiography (ECG) of diabetic patients who applied to the Ministry of Health University Gülhane Training Research Underwater and Hyperbaric Medicine Clinic were compared before and after the first HBO2 therapy session. When ECG findings were analyzed at the end of a session of HBO2 exposure, a statistically significant increase was observed in the QTc, QTc dispersion measurements (p < 0.001, p = 0.015, respectively). In cardiac enzymes there was statistically significant increase in troponin I values after an HBO2 therapy session, but no statistically significant change was observed in Pro-BNP (p = 0.009, p = 0.300, respectively). Short-term exposure to HBO2 therapy had statistically significant changes in troponin I, QT and QTc in patients with DM, which did not reach clinical significance. Despite very little evidence of cardiac dysfunction, we recommend caution HBO2 therapy in patients with DM and the need for further investigation of these measurements.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90703286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful treatment of radiation-induced vaginal soft tissue radionecrosis with HBO2. HBO2成功治疗放射性阴道软组织放射性坏死。

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01

John McGlynn, Marvin Heyboer

{"title":"Successful treatment of radiation-induced vaginal soft tissue radionecrosis with HBO2.","authors":"John McGlynn, Marvin Heyboer","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Radiation therapy to the pelvis can result in radiation-induced vaginal soft tissue necrosis. This significantly impacts quality of life. Studies evaluating the efficacy of HBO2 are limited.Methods: In this retrospective report, we reviewed the medical records of patients treated with once-daily HBO2 for radiation-induced vaginal soft tissue necrosis. We included females between the ages of 18 to 90 with history of pelvic cancer treated with radiotherapy and resultant soft tissue radionecrosis. Data collected included age, comorbid disease, cancer type, radiation dose, HBO2 treatment pressure, time, and total treatments. Primary outcome was improvement of radionecrosis; secondary outcomes were improvement of pelvic pain, reduction in need for analgesia, and improvement of vaginal bleeding.Results: Seven patients were identified, of which six received HBO2. One patient had a vaginal fistula. Four patients had documented improvement of radionecrosis. Four out of five patients with pelvic pain had resolution of their pain, with two patients no longer requiring opioid analgesia. Two patients who presented with vaginal bleeding showed improvement with one resolved and one significantly decreased requiring no further hospitalization or transfusion. One patient experienced no documented improvement in any of the measured outcomes.Conclusion: In this case series, five out of six (83%) patients treated with HBO2 for radiation-induced vaginal necrosis improved in at least one outcome measure. While the sample size is small, these results add to the data available that supports the use of HBO2 in suitable candidates without contraindications who have symptoms related to radiation-induced vaginal soft tissue necrosis.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10783507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lethal event in scuba diving with self-contained breathing apparatus: a forensic study 带独立呼吸器的水肺潜水中的致命事件:一项法医研究

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.22462/01.01.2023.10

Mirko Leonardelli, F. Mele, M. Calvano, Enrica Macorano, Stefano Duma, Giovanni De Gabriele, F. Introna

{"title":"Lethal event in scuba diving with self-contained breathing apparatus: a forensic study","authors":"Mirko Leonardelli, F. Mele, M. Calvano, Enrica Macorano, Stefano Duma, Giovanni De Gabriele, F. Introna","doi":"10.22462/01.01.2023.10","DOIUrl":"https://doi.org/10.22462/01.01.2023.10","url":null,"abstract":"Introduction: In fatal accidents during scuba diving it is necessary to differentiate a death from primary drowning from a secondary drowning death primarily due to other etiopathogenetic factors. The inhalation of water can only be the end point of a series of events alone capable of causing the diver’s exitus. The aim of this study is demonstrate that even low-risk heart diseases in daily life become potentially fatal during scuba diving. Methods: In this case series we describe all cases of death in the course of diving that came to the observation of the Forensic Institute of the University of Bari over a period of 20 years (2000-2020). Judicial autopsy was performed on all subjects with ancillary execution of histological and toxicological investigations. Results: The results of the medicolegal investigations carried out in the complex identified heart failure with acute myocardial infarction as the cause of death in four cases characterized by severe myocardiocoronarosclerosis, a primary drowning in a subject without previous pathological substrate in one case, and a terminal atrial fibrillation induced by acute dynamic heart failure due to functional overload of the right ventricle in one case Conclusion: Our study demonstrates that lethal events during diving are often related to the presence of unrecognized or subclinical cardiovascular diseases. Such deaths could be prevented and avoided if a greater regulatory sensitivity to the prevention and control of diving was encouraged, considering both the inherent risks of this activity and the possible unrecognized or underestimated pathologies.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79134702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A fully automated algorithm for heart rate detection in post-dive precordial Doppler ultrasound. 潜水后心前多普勒超声心率检测的全自动算法。

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01

Andrew Hoang, David Q Le, S Lesley Blogg, Arian Azarang, Paul A Dayton, Peter Lindholm, Virginie Papadopoulou

{"title":"A fully automated algorithm for heart rate detection in post-dive precordial Doppler ultrasound.","authors":"Andrew Hoang, David Q Le, S Lesley Blogg, Arian Azarang, Paul A Dayton, Peter Lindholm, Virginie Papadopoulou","doi":"","DOIUrl":"","url":null,"abstract":"Background: Doppler ultrasound is used currently in decompression research for the evaluation of venous gas emboli (VGE). Estimation of heart rate from post-dive Doppler ultrasound recordings can provide a tool for the evaluation of physiological changes from decompression stress, as well as aid in the development of automated VGE detection algorithms that relate VGE presence to cardiac activity.Method: An algorithm based on short-term autocorrelation was developed in MATLAB to estimate the heart rate in post-dive precordial Doppler ultrasound. The algorithm was evaluated on 21 previously acquired and labeled precordial recordings spanning Kisman-Masurel (KM) codes of 111-444 (KM I-IV) with manually derived instantaneous heart rates.Results: A window size of at least two seconds was necessary for robust and accurate instantaneous heart rate estimation with a mean error of 1.56 ± 7.10 bpm. Larger window sizes improved the algorithm performance, at the cost of beat-to-beat heart rate estimates. We also found that our algorithm provides good results for low KM grade Doppler recordings with and without flexion, and high KM grades without flexion. High KM grades observed after movement produced the greatest mean absolute error of 6.12 ± 8.40 bpm.Conclusion: We have developed a fully automated algorithm for the estimation of heart rate in post-dive precordial Doppler ultrasound recordings.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10774667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Speech therapy and hyperbaric oxygen for aphasia after carbon monoxide intoxication. 高压氧治疗一氧化碳中毒后失语症。

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01

Marta Ruiz-Mambrilla, Antonio Dueñas-Ruiz, José L Pérez-Castrillón, Iciar Usategui-Martín, Antonio Dueñas-Laita

引用次数: 0

Cardiac arrest in diving: The key to success. 潜水时心脏骤停:成功的关键。

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01

Henry James Jonathon Hughes, Stuart McPhail, Nathan Wilson, Matthew Osborne

{"title":"Cardiac arrest in diving: The key to success.","authors":"Henry James Jonathon Hughes, Stuart McPhail, Nathan Wilson, Matthew Osborne","doi":"","DOIUrl":"","url":null,"abstract":"This case report describes the successful management of an out-of-hospital arrest in a diver following a suspected arterial gas embolism (AGE). It illustrates both the inherent risks of diving and the importance of prompt and effective implementation of the \"chain of survival\" from bystanders. Rapid on-scene responses from paramedics and helicopter emergency medical services facilitated prompt evacuation to a Category 1 (multiplace) recompression chamber (RCC) where specialists in cardiology and hyperbaric medicine were available. Alternative causes of cardiac arrest were considered, with a presumed AGE successfully treated with multiple rounds of hyperbaric oxygen therapy. The key factors which led to this successful outcome are discussed, including early recognition and call for help, competent cardiopulmonary resuscitation, and direct evacuation to a Category 1 RCC, with additional consideration of the diagnosis leading to cardiac arrest. The case clearly illustrates the need for all those involved in diving regularly to be competent and confident in performing basic life support, as well as the awareness of the emergency services of the need for diving casualties to be treated at appropriate hyperbaric facilities. Were it not for the simple, prompt and effective treatment this diver received, both on scene and in hospital, it is highly unlikely that such a positive outcome would have been achieved.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10774666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyperbaric hydrogen therapy improves secondary brain injury after head trauma 高压氢治疗可改善颅脑外伤后继发性脑损伤

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.22462/01.01.2023.43

Yohei Otsuka, S. Tomura, T. Toyooka, S. Takeuchi, A. Tomiyama, Tomoko Omura, Daizoh Saito, K. Wada

{"title":"Hyperbaric hydrogen therapy improves secondary brain injury after head trauma","authors":"Yohei Otsuka, S. Tomura, T. Toyooka, S. Takeuchi, A. Tomiyama, Tomoko Omura, Daizoh Saito, K. Wada","doi":"10.22462/01.01.2023.43","DOIUrl":"https://doi.org/10.22462/01.01.2023.43","url":null,"abstract":"Background: The pathophysiology of traumatic brain injury (TBI) is caused by the initial physical damage and by the subsequent biochemical damage (secondary brain injury). Oxidative stress is deeply involved in secondary brain injury, so molecular hydrogen therapy may be effective for TBI. Hydrogen gas shows the optimal effect at concentrations of 2% or higher, but can only be used up to 1.3% in the form of a gas cylinder mixed with oxygen gas, which may not be sufficiently effective. The partial pressure of hydrogen increases in proportion to the pressure, so hyperbaric hydrogen therapy (HBH2) is more effective than that at atmospheric pressure. Methods: A total of 120 mice were divided into three groups: TBI + non-treatment group (TBI group; n = 40), TBI + HBH2 group (n = 40), and non-TBI + non-treatment group (sham group; n = 40). The TBI and TBI + HBH2 groups were subjected to moderate cerebral contusion induced by controlled cortical impact. The TBI + HBH2 group received hyperbaric hydrogen therapy at 2 atmospheres for 90 minutes, at 30 minutes after TBI. Brain edema, neuronal cell loss in the injured hippocampus, neurological function, and cognitive function were evaluated. Results: The TBI + HBH2 group showed significantly less cerebral edema (p < 0.05). Residual hippocampal neurons were significantly more numerous in the TBI + HBH2 group on day 28 (p < 0.05). Neurological score and behavioral tests showed the TBI + HBH2 group had significantly reduced hyperactivity on day 14 (p < 0.01). Conclusion: Hyperbaric hydrogen therapy may be effective for posttraumatic secondary brain injury.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82202655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0