Undersea and Hyperbaric Medicine最新文献_第8页

Hyperbaric hydrogen therapy improves secondary brain injury after head trauma 高压氢治疗可改善颅脑外伤后继发性脑损伤

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.22462/01.01.2023.43

Yohei Otsuka, S. Tomura, T. Toyooka, S. Takeuchi, A. Tomiyama, Tomoko Omura, Daizoh Saito, K. Wada

{"title":"Hyperbaric hydrogen therapy improves secondary brain injury after head trauma","authors":"Yohei Otsuka, S. Tomura, T. Toyooka, S. Takeuchi, A. Tomiyama, Tomoko Omura, Daizoh Saito, K. Wada","doi":"10.22462/01.01.2023.43","DOIUrl":"https://doi.org/10.22462/01.01.2023.43","url":null,"abstract":"Background: The pathophysiology of traumatic brain injury (TBI) is caused by the initial physical damage and by the subsequent biochemical damage (secondary brain injury). Oxidative stress is deeply involved in secondary brain injury, so molecular hydrogen therapy may be effective for TBI. Hydrogen gas shows the optimal effect at concentrations of 2% or higher, but can only be used up to 1.3% in the form of a gas cylinder mixed with oxygen gas, which may not be sufficiently effective. The partial pressure of hydrogen increases in proportion to the pressure, so hyperbaric hydrogen therapy (HBH2) is more effective than that at atmospheric pressure. Methods: A total of 120 mice were divided into three groups: TBI + non-treatment group (TBI group; n = 40), TBI + HBH2 group (n = 40), and non-TBI + non-treatment group (sham group; n = 40). The TBI and TBI + HBH2 groups were subjected to moderate cerebral contusion induced by controlled cortical impact. The TBI + HBH2 group received hyperbaric hydrogen therapy at 2 atmospheres for 90 minutes, at 30 minutes after TBI. Brain edema, neuronal cell loss in the injured hippocampus, neurological function, and cognitive function were evaluated. Results: The TBI + HBH2 group showed significantly less cerebral edema (p < 0.05). Residual hippocampal neurons were significantly more numerous in the TBI + HBH2 group on day 28 (p < 0.05). Neurological score and behavioral tests showed the TBI + HBH2 group had significantly reduced hyperactivity on day 14 (p < 0.01). Conclusion: Hyperbaric hydrogen therapy may be effective for posttraumatic secondary brain injury.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"63 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82202655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of pediatric cerebral radiation necrosis using hyperbaric oxygenation 高压氧治疗小儿脑放射性坏死

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.22462/01.01.2023.4

K. Johnson-Arbor

{"title":"Treatment of pediatric cerebral radiation necrosis using hyperbaric oxygenation","authors":"K. Johnson-Arbor","doi":"10.22462/01.01.2023.4","DOIUrl":"https://doi.org/10.22462/01.01.2023.4","url":null,"abstract":"Introduction: Cerebral radiation necrosis is a rarely encountered in pediatric patients. This case report describes a child with cerebral radiation necrosis who was successfully treated using a corticosteroids, bevacizumab, and hyperbaric oxygenation. Case Report: A 3-year-old boy developed progressive extremity weakness six months after completion of radiation therapy for treatment of a neuroepithelial malignancy. Treatment with corticosteroids and bevacizumab was initiated, but his symptoms did not improve, and he was then referred for hyperbaric oxygen therapy. After completion of 60 hyperbaric treatments, he experienced significant improvements in mobility which remained stable over the next year. Discussion: Cerebral radiation necrosis typically presents in children with symptoms of ataxia or headache. Corticosteroids and bevacizumab are common treatments, but hyperbaric oxygen therapy has also been studied as a therapeutic modality for this condition. When considering the use of hyperbaric oxygenation in pediatric patients, careful attention to treatment planning and patient safety can reduce the risks of adverse events such as middle ear barotrauma and confinement anxiety. Conclusion: Hyperbaric oxygenation, in addition to other available pharmacologic therapies, should be considered for the treatment of pediatric patients with cerebral radiation necrosis.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"16 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81315636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyperbaric oxygen administration mitigates the expression of kidney injury molecule-1, inflammatory cytokines, and apoptotic markers during cold ischemic time in kidney transplantation 高压氧可减轻肾移植冷缺血期间肾损伤分子-1、炎症细胞因子和凋亡标志物的表达

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.22462/01.01.2023.2

Başak Büyük, Özlem Öztopuz

{"title":"Hyperbaric oxygen administration mitigates the expression of kidney injury molecule-1, inflammatory cytokines, and apoptotic markers during cold ischemic time in kidney transplantation","authors":"Başak Büyük, Özlem Öztopuz","doi":"10.22462/01.01.2023.2","DOIUrl":"https://doi.org/10.22462/01.01.2023.2","url":null,"abstract":"The aim of this study was to investigate the effect of hyperbaric oxygen (HBO2) administration applied during cold ischemic time to organs removed from donors before kidney transplantation. A total of 24 rats were divided into three groups: Group 1 was the control group, Group 2 received 60 minutes of HBO2 at 2.5 atmospheres absolute, and Group 3 received 120 minutes of 2.5 ATA HBO2. The renal artery was entered with a polyethylene catheter and perfused with a standard organ preservation solution. Falcon tubes containing organs obtained from rats in Groups 2 and 3 were placed in a box supported by ice blocks. The temperature was kept constant at 4 °C and the box was placed in a pressure tank with 2.5 ATA HBO2. HBO2 was applied for 60 and 120 minutes, respectively. Organ samples were harvested at the end of 24 hours for histopathological evaluation, immunohistochemical analysis of TNF-α and IL-18, TUNEL analysis for apoptosis, and gene expression levels of kidney injury molecule-1 (KIM-1) and caspase-3. In histopathological examinations, hematoxylin and eosin staining was performed and samples were evaluated for tubular necrosis and vacuolization criteria. Group 2 and Group 3 had significant decreases compared to Group 1 in this regard. Immunohistochemical staining was performed for TNF-α, IL-18, and apoptosis levels; significant decreases were found in Groups 2 and 3. There were significant decreases in Groups 2 and 3 for KIM-1 and caspase-3 gene expression levels compared to Group 1, as well. Thus, it was demonstrated that during the cold ischemic time before kidney transplantation, HBO2 administration to organs removed from donors can reduce apoptotic cell numbers, inflammatory cytokine release, and histopathological damage to the organs as well as decreasing the expression of the KIM-1 gene, which is an indicator of kidney damage.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"56 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83876620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Decompression sickness followed by diabetic ketoacidosis and sepsis shock: an unusual case report 减压病并发糖尿病酮症酸中毒及脓毒症休克1例

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.22462/01.01.2023.13

Anwei Liu, Xiaogan Hou, Jian-Yun Nie, Q. Wen, Zhi-guo Pan

{"title":"Decompression sickness followed by diabetic ketoacidosis and sepsis shock: an unusual case report","authors":"Anwei Liu, Xiaogan Hou, Jian-Yun Nie, Q. Wen, Zhi-guo Pan","doi":"10.22462/01.01.2023.13","DOIUrl":"https://doi.org/10.22462/01.01.2023.13","url":null,"abstract":"Decompression sickness (DCS) is a disease caused by abrupt change of extracorporeal pressure, with varying severity. Symptoms range from mild musculoskeletal pain to severe organ dysfunction and death, especially among patients with chronic underlying disease. Here, we report an unusual case of a 49-year-old man who experienced DCS after a dive to a depth of 38 meters. The patient’s symptoms progressed, starting with mild physical discomfort that progressed to disturbance of consciousness on the second morning. During hospitalization, we identified that in addition to DCS he had also developed diabetic ketoacidosis, septic shock, and rhabdomyolysis. After carefully balancing the benefits and risks, we decided to provide a series of supportive treatment to sustain vital signs, including ventilation support, sugar-reducing therapy, fluid replacement, and anti-infection medications. We then administered delayed hyperbaric oxygen (HBO2) when his condition was stable. Ultimately, the patient recovered without any sequelae. This is the first case report of a diver suffering from DCS followed by diabetic ketoacidosis and septic shock. We have learned that when DCS, along with other critical illness is highly suspected, it is essential to assess the condition comprehensively and focus on the principal contradiction.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"34 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88958361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inner ear decompression sickness after a routine dive and recompression chamber drill: A case report 常规潜水和再压缩室训练后的内耳减压病1例报告

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.22462/01.01.2023.27

Dale Parsons, E. Utz, Grant A Kidd, Gina R Virgilio

{"title":"Inner ear decompression sickness after a routine dive and recompression chamber drill: A case report","authors":"Dale Parsons, E. Utz, Grant A Kidd, Gina R Virgilio","doi":"10.22462/01.01.2023.27","DOIUrl":"https://doi.org/10.22462/01.01.2023.27","url":null,"abstract":"Inner ear decompression sickness (IEDCS) is an uncommon diving-related injury affecting the vestibulocochlear system, with symptoms typically including vertigo, tinnitus and hearing loss, either in isolation or in combination. Classically associated with deep, mixed-gas diving, more recent case series have shown that IEDCS is indeed possible after seemingly innocuous recreational dives, and there has been one previous report of IEDCS following routine hyperbaric chamber operations. The presence of right-to-left shunt (RLS), dehydration and increases in intrathoracic pressure have been identified as risk factors for IEDCS, and previous studies have shown a predominance of vestibular rather than cochlear symptoms, with a preference for lateralization to the right side. Most importantly, rapid identification and initiation of recompression treatment are critical to preventing long-term or permanent inner ear deficits. This case of a U.S. Navy (USN) diver with previously unidentified RLS reemphasizes the potential for IEDCS following uncomplicated diving and recompression chamber operations – only the second reported instance of the latter.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"17 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75887181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Barodontalgia during hyperbaric oxygen therapy of an 8-year-old male: a case report 高压氧治疗期间的一名8岁男性压力痛:1例报告

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.22462/01.01.2023.29

Melisa Öçbe, Selin Gamze Sümen, Busra Dilara Altun, A. Dumlu

{"title":"Barodontalgia during hyperbaric oxygen therapy of an 8-year-old male: a case report","authors":"Melisa Öçbe, Selin Gamze Sümen, Busra Dilara Altun, A. Dumlu","doi":"10.22462/01.01.2023.29","DOIUrl":"https://doi.org/10.22462/01.01.2023.29","url":null,"abstract":"Barodontalgia, barometric pressure-induced dental pain, may occur during hyperbaric oxygen therapy due to pressure changes. This case report represents an 8-year-old male patient with barodontalgia. The patient declared a severe toothache during hyperbaric therapy. The diving medicine specialist referred the patient to the dental clinician immediately. Upon clinical examination, the pain was thought to be caused by caries lesions of the deciduous teeth in the left maxillary molar region. Tooth extraction was suggested. After extraction, patient continued hyperbaric oxygen therapy sessions without any pain. Patient was recommended for a session to intraoral and radiographic examination one week after the extraction. In conclusion, caries lesions and faulty restorations should be examined before hyperbaric oxygen therapy sessions. Even though barodontalgia is a rare phenomenon, dental examination is essential to avoid these kinds of pain-related complications. All carious lesions and defective restorations must be treated, if necessary. Removal of faulty restorations, and management of inflammation as part of the treatment is suggested before being exposed to pressure changes.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"37 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77794300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chondronecrosis of the cricoid treated with hyperbaric oxygen therapy: A case series 高压氧治疗环状软骨坏死:一个病例系列

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.22462/01.01.2023.30

J. D. Spencer, Tyler Connely, J. Cooper, J. Dowdall

引用次数: 0

Aerobic exercise performance is reduced following prolonged cold-water immersion 长时间的冷水浸泡会降低有氧运动的表现

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.22462/01.01.2023.33

Hayden W. Hess, Z. Schlader, Blair D. Johnson, Riana R. Pryor, D. Hostler

{"title":"Aerobic exercise performance is reduced following prolonged cold-water immersion","authors":"Hayden W. Hess, Z. Schlader, Blair D. Johnson, Riana R. Pryor, D. Hostler","doi":"10.22462/01.01.2023.33","DOIUrl":"https://doi.org/10.22462/01.01.2023.33","url":null,"abstract":"We tested the hypotheses that self-paced aerobic exercise performance is reduced following four hours of cold-water immersion when breathing air and further reduced when breathing 100% oxygen (O2). Nine healthy adults (four women; age 24 ± 3 years; body fat 17.9 ± 6.4 %; V̇O2max 48 ± 9 mL·kg·minute-1) completed three visits: a no-immersion control trial and two experimental trials consisting of a four-hour cold-water immersion (20.1±0.3C) either breathing air (FIO2 = 0.21) or O2 (FIO2 = 1.0). During the no-immersion control trial and following immersion in the experimental trials, subjects first completed a 60-minute ruck-march carrying 20% of body mass in a rucksack, immediately followed by an unweighted, self-paced 5-km time trial on a motorized treadmill. Core temperature, heart rate, and rating of perceived exertion were recorded every 1,000 meters during the 5-km time trial. Data are presented mean ± SD. Time trial performance was reduced following immersion in both the 100% O2 trial (32 ± 6 minutes; p=0.01) and air trial (32 ± 5 minutes; p=0.01) compared to the control trial (28 ± 4 minutes). However, there was no difference between the 100% O2 and air trials (p=0.86). Heart rate, core temperature, and rating of perceived exertion increased during the time trial (time effect: p<0.01), but were not different between trials (trial effect: p≥0.33). These findings suggests that prolonged cold-water immersion attenuates self-paced aerobic exercise performance, but does not appear to be further affected by breathing gas type.","PeriodicalId":49396,"journal":{"name":"Undersea and Hyperbaric Medicine","volume":"49 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77618987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Altitude diving on a closed-circuit oxygen rebreather: A case report 用闭路换气器高空潜水1例报告

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.22462/01.01.2023.12

J. Conard

引用次数: 0

Long-term eff ects of carbon monoxide poisoning at Miike coal mine: A 33-year follow-up study Miike煤矿一氧化碳中毒的长期影响:33年随访研究

IF 0.9 4区医学

Undersea and Hyperbaric Medicine Pub Date : 2023-01-01 DOI: 10.22462/01.01.2023.40

Koichi Mimura, M. Harada, S. Sumiyoshi, Gyo Toya, M. Takagi, E. Fujita, Akira Takata, S. Tatetsu

引用次数: 0