Recent Patents on Nanotechnology最新文献

筛选
英文 中文
Historical Neighborhoods of Edirne 埃迪尔内的历史街区
4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-03-20 DOI: 10.2174/9789815223040124010003
Nevnihal Erdoğan
{"title":"Historical Neighborhoods of Edirne","authors":"Nevnihal Erdoğan","doi":"10.2174/9789815223040124010003","DOIUrl":"https://doi.org/10.2174/9789815223040124010003","url":null,"abstract":"Developing out of its former role as an old Byzantine fortress, the city advanced greatly as a Turkish-Muslim city in the Ottoman Empire. The main means of growth resulted from the establishment of benevolent facilities managed by a charitable foundation. These charitable foundations, known as Wakfs, had a significant impact on facilitating the shift towards settled living in both Anatolia and Rumelia. The advancement was greatly enhanced by the buildings, constructions and enhancement efforts directed by the successive sultans and prominent state members of varying levels of authority (second-degree, and third-degree officials of the state). Edirne was established based on the formula that declares, “there is a mosque in the center of the neighborhood and the neighborhood is a physical unit as well as a social unit”, and this type of settlement approach was then implemented in most neighborhoods. The chapter examines the various original establishments, such as mosques, baths, fountains, and soup kitchens, as well as the layout of settlements. Today, the old neighborhoods within each district have amalgamated to create novel neighborhoods. The fundamental constituents of the old neighborhoods in the nine regions encompassing public kitchens, mosques, baths, charitable endowments, thoroughfares, and residences endure in certain neighborhoods to a certain extent, whereas in other areas, they have become entirely extinct. In the existing housing settlements, one can see the effect of traditional Anatolian housing types, Hilani and Megaron, in the plans of houses in the outer districts, and even in the city center. Plan types with outer sofas could have one, two, three, or four rooms, while two- and three-roomed examples are more common.","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"1 1","pages":"15-37"},"PeriodicalIF":0.0,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147899421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Formulation of Solid Lipid Nanoparticles Loaded with Rosiglitazone and Probiotic: Optimization and In-vitro Characterization 含罗格列酮和益生菌的固体脂质纳米颗粒的制备:优化与体外表征
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-02-02 DOI: 10.2174/0118722105268801231203144554
Nitish Kumar, Nidhi Tyagi, Sidharth Mehan, Alok Pratap Singh
{"title":"Formulation of Solid Lipid Nanoparticles Loaded with Rosiglitazone and Probiotic: Optimization and In-vitro Characterization","authors":"Nitish Kumar, Nidhi Tyagi, Sidharth Mehan, Alok Pratap Singh","doi":"10.2174/0118722105268801231203144554","DOIUrl":"https://doi.org/10.2174/0118722105268801231203144554","url":null,"abstract":"Introduction: In the present study, solid lipid nanoparticles loaded with Rosiglitazone and probiotics were prepared via solvent emulsification diffusion. As a lipid and surfactant, Gleceryl monostearate and Pluronic -68 were used in the formulation process. background: Nanotechnology is essential for developing novel methods for transporting potentially therapeutic and symptomatic substances to specific regions of the central nervous system. Since these formulations reduce the long-term adverse effects associated with the aberrant distribution of medications, they increase the drug concentration at the site of action, thereby enhancing therapeutic efficacy. Method: During characterization, it was determined that ingredient quantity variations significantly impacted Rosiglitazone loading capacity, particle size, polydispersity index, etc. In an optimized formulation of RSG-PB loaded SLNs, spherical particles with a mean particle size of 147.66±1.52 nm, PDI of 0.42±0.02, and loading capacity of 45.36±0.20 were identified. Result: Moreover, the developed SLNs had the potential to discharge the drug for up to 24 hours, as predicted by Higuchi's pharmacokinetic model. The SLNs were stable at 25⁰C/60%RH for up to 60 days. There was little to no change in particle size, PDI, or loading capacity. In addition, the number of probiotic bacteria was determined using the standard plate count procedure. Further, the antioxidant effect of the prepared formulation is evaluated using the DPPH assay method. Conclusion: This study concludes that the method used to fabricate RSG-probiotic-loaded SLNs is straightforward and yields favorable results regarding various parameters, including sustained release property, particle size, PDI, and percent drug loading stability. Furthermore, DPPH radical scavenging activity shows the high antioxidant potential of RSG-PB SLNs when compared to RSG and probiotics alone.","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"10 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139662459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
WITHDRAWN: Wheatgrass (Triticum aestivum) Extract Loaded Chitosan Solid Lipid Nanoparticles: Formulation, Physicochemical Characterisation and Cytotoxic Potential 小麦草(Triticum Aestivum)提取物负载壳聚糖固体脂质纳米颗粒:配方、理化特性和细胞毒性潜力。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-10 DOI: 10.2174/0118722105270861231128081639
Neha Minocha, Parijat Pandey, Nidhi Sharma, Sangita Saini
{"title":"WITHDRAWN: Wheatgrass (Triticum aestivum) Extract Loaded Chitosan Solid Lipid Nanoparticles: Formulation, Physicochemical Characterisation and Cytotoxic Potential","authors":"Neha Minocha, Parijat Pandey, Nidhi Sharma, Sangita Saini","doi":"10.2174/0118722105270861231128081639","DOIUrl":"10.2174/0118722105270861231128081639","url":null,"abstract":"<p><p>Since the content of the article shows a high degree of similarity to a previously published work by the same group of authors, the article has been withdrawn from the journal Recent Patents on Nanotechnology with the consent of the Editor-in-Chief.</p><p><p>Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.</p><p><p>The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policiesmain.php</p><p><strong>Bentham science disclaimer: </strong>It is a condition of publication that manuscripts submitted to this journal have not been published and will not be\u0000simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139425837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Imaging and Non-imaging Analytical Techniques Used for Drug Nanosizing and their Patents: An Overview. 用于药物纳米化的成像和非成像分析技术及其专利综述。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/0118722105243388230920013508
Vijay Agarwal, Meenakshi Bajpai
{"title":"Imaging and Non-imaging Analytical Techniques Used for Drug Nanosizing and their Patents: An Overview.","authors":"Vijay Agarwal, Meenakshi Bajpai","doi":"10.2174/0118722105243388230920013508","DOIUrl":"10.2174/0118722105243388230920013508","url":null,"abstract":"<p><strong>Background: </strong>Nanosizing is widely recognized as an effective technique for improving the solubility, dissolution rate, onset of action, and bioavailability of poorly water-soluble drugs. To control the execution and behavior of the output product, more advanced and valuable analytical techniques are required.</p><p><strong>Objective: </strong>The primary intent of this review manuscript was to furnish the understanding of imaging and non-imaging techniques related to nanosizing analysis by focusing on related patents. In addition, the study also aimed to collect and illustrate the information on various classical (laser diffractometry, photon correlation spectroscopy, zeta potential, laser Doppler electrophoresis, X-ray diffractometry, differential scanning calorimeter, scanning electron microscopy, transmission electron microscopy), new, and advanced analytical techniques (improved dynamic light scattering method, Brunauer-Emmett- Teller method, ultrasonic attenuation, biosensor), as well as commercial techniques, like inductively coupled plasma mass spectroscopy, aerodynamic particle sizer, scanning mobility particle sizer, and matrix- assisted laser desorption/ionization mass spectroscopy, which all relate to nano-sized particles.</p><p><strong>Methods: </strong>The present manuscript has taken a fresh look at the various aspects of the analytical techniques utilized in the process of nanosizing, and has achieved this through the analysis of a wide range of peer-reviewed literature. All summarized literature studies provide the information that can meet the basic needs of nanotechnology.</p><p><strong>Results: </strong>A variety of analytical techniques related to the nanosizing process have already been established and have great potential to weed out several issues. However, the current scenarios require more relevant, accurate, and advanced analytical techniques that can minimize the time and deviations associated with different instrumental and process parameters. To meet this requirement, some new and more advanced analytical techniques have recently been discovered, like ultrasonic attenuation technique, BET technique, biosensors, etc. Conclusion: The present overview certifies the significance of different analytical techniques utilized in the nanosizing process. The overview also provides information on various patents related to sophisticated analytical tools that can meet the needs of such an advanced field. The data show that the nanotechnology field will flourish in the coming future.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":"494-518"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89720162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanocrystal Materials for Resistive Memory and Artificial Synapses: Progress and Prospects. 用于电阻记忆和人工突触的纳米晶体材料:进展与前景》。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/1872210517666230413092108
Yingchun Chen, Dunkui Chen, Chi Zhang, Xian Zhang
{"title":"Nanocrystal Materials for Resistive Memory and Artificial Synapses: Progress and Prospects.","authors":"Yingchun Chen, Dunkui Chen, Chi Zhang, Xian Zhang","doi":"10.2174/1872210517666230413092108","DOIUrl":"10.2174/1872210517666230413092108","url":null,"abstract":"<p><strong>Background: </strong>Resistive random-access memory (RRAM) is considered to be the most promising next-generation non-volatile memory because of its low cost, low energy consumption, and excellent data storage characteristics. However, the on/off (SET/RESET) voltages of RRAM are too random to replace the traditional memory. Nanocrystals (NCs) offer an appealing option for these applications since they combine excellent electronic/optical properties and structural stability and can address the requirements of low-cost, large-area, and solution-processed technologies. Therefore, the doping NCs in the function layer of RRAM are proposed to localize the electric field and guide conductance filaments (CFs) growth.</p><p><strong>Objective: </strong>The purpose of this article is to focus on a comprehensive and systematical survey of the NC materials, which are used to improve the performance of resistive memory (RM) and optoelectronic synaptic devices and review recent experimental advances in NC-based neuromorphic devices from artificial synapses to light-sensory synaptic platforms.</p><p><strong>Methods: </strong>Extensive information related to NCs for RRAM and artificial synapses and their associated patents were collected. This review aimed to highlight the unique electrical and optical features of metal and semiconductor NCs for designing future RRAM and artificial synapses.</p><p><strong>Results: </strong>It was demonstrated that doping NCs in the function layer of RRAM could not only improve the homogeneity of SET/RESET voltage but also reduce the threshold voltage. At the same time, it could still increase the retention time and provide the probability of mimicking the bio-synapse.</p><p><strong>Conclusion: </strong>NC doping can significantly enhance the overall performance of RM devices, but there are still many problems to be solved. This review highlights the relevance of NCs for RM and artificial synapses and also provides a perspective on the opportunities, challenges, and potential future directions.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":"237-255"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9687973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel and Innovative Approach of Nanotechnology with their Applications in the Management of Infectious Disease, Tuberculosis: An Overview. 纳米技术的创新方法及其在传染病、结核病管理中的应用综述。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/1872210516666220523122724
Sonia Singh, Ashima Ahuja
{"title":"Novel and Innovative Approach of Nanotechnology with their Applications in the Management of Infectious Disease, Tuberculosis: An Overview.","authors":"Sonia Singh, Ashima Ahuja","doi":"10.2174/1872210516666220523122724","DOIUrl":"10.2174/1872210516666220523122724","url":null,"abstract":"<p><p>Tuberculosis (TB) is considered a significant health problem caused by <i>Mycobacterium tuberculosis</i>. It is one of the second-deadly infectious diseases right after AIDS. Several factors such as poor patient compliance, high dose intake, low drug bioavailability and prolonged treatment of disease are responsible for the prevalence of multi-drug resistance tuberculosis and extensively drug-resistant tuberculosis cases. Therefore, developing such drug-resistant bacterial strains has created a robust and efficient system that can improve the therapeutic effectiveness of anti-tubercular drugs. This review manuscript highlights the therapeutic outcomes of a nanotechnology-based drug delivery system in treating TB. Various novel nanoformulations for anti-mycobacterial drugs have been explored. Such novel approaches would have shown several advantages such as sustained/controlled drug release, reduced dose frequency, and resolved poor patient compliance over many free anti-tubercular drugs. This framework will provide valuable information on various nanoparticle-based technology employed in treating TB infectious disease. Patent data were searched in google patent and nanoformulations outcomes for TB management improves health of patients.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"1 1","pages":"140-163"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41333862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Critical Appraisal of Functionalized 2-Dimensional Carbon-Based Nanomaterials for Drug Delivery Applications. 功能化二维碳基纳米材料在药物递送应用中的关键评价。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/1872210518666230911150337
Dilpreet Singh, G D Gupta, Nimish Gupta, Princi Verma, Abhisek Dey, Simranjeet Kaur, Akshay Kumar, Namandeep Raj
{"title":"A Critical Appraisal of Functionalized 2-Dimensional Carbon-Based Nanomaterials for Drug Delivery Applications.","authors":"Dilpreet Singh, G D Gupta, Nimish Gupta, Princi Verma, Abhisek Dey, Simranjeet Kaur, Akshay Kumar, Namandeep Raj","doi":"10.2174/1872210518666230911150337","DOIUrl":"10.2174/1872210518666230911150337","url":null,"abstract":"<p><p>The development of an efficient and innovative drug delivery system is essential to improve the pharmacological parameters of the medicinal compound or drug. The technique or manner used to improve the pharmacological parameters plays a crucial role in the delivery system. In the current scenario, various drug delivery systems are available where nanotechnology has firmly established itself in the field of drug delivery. One of the most prevalent elements is carbon with its allotropic modifications such as graphene-based nanomaterials, carbon nanotubes, carbon dots, and carbon fullerenes, these nanomaterials offer notable physiochemical and biochemical properties for the delivery applications due to their smaller size, surface area, and ability to interact with the cells or tissues. The exceptional physicochemical properties of carbon-based 2D nanomaterials, such as graphene and carbon nanotubes, make them attractive candidates for drug delivery systems. These nanomaterials offer a large surface area, high drug loading capacity, and tunable surface chemistry, enabling efficient encapsulation, controlled release, and targeted delivery of therapeutic agents. These properties of the nanomaterials can be exploited for drug delivery applications, like assisting the target delivery of drugs and aiding combination molecular imaging. This review emphasizes on the recent patents on 2D carbon-based nanomaterial and their role in drug delivery systems. Carbon-based 2D nanomaterials present a wealth of opportunities for advanced drug delivery systems. Their exceptional properties and versatility offers great potential in improving therapeutic efficacy, minimizing side effects, and enabling personalized medicine and the recent patents on 2D nanomaterial.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":"479-493"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10590718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two-dimensional MXene Nanomaterials: Preparation, Structure Modulation and the Applications in Electrochemical Energy Storage. 二维 MXene 纳米材料:二维 MXene 纳米材料:制备、结构调制及在电化学储能中的应用。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/1872210517666230427161120
Yingchun Chen, Bei Yu, Lingling Peng
{"title":"Two-dimensional MXene Nanomaterials: Preparation, Structure Modulation and the Applications in Electrochemical Energy Storage.","authors":"Yingchun Chen, Bei Yu, Lingling Peng","doi":"10.2174/1872210517666230427161120","DOIUrl":"10.2174/1872210517666230427161120","url":null,"abstract":"<p><strong>Background: </strong>MXenes have attracted intensive attention owing to their unique twodimensional (2D) layered structure, high specific surface area, excellent conductivity, superior surface hydrophilicity, and chemical stability. In recent years, selective etching of the A element layers from MAX phases by fluorine-containing etchants (HF, LiF-HCl, <i>etc</i>) is a common method to prepare multilayered MXene nanomaterials (NMs) with plentiful surface terminations. At present, many studies have been reported on the use of fluorine-free etchants (NaOH, ZnCl<sub>2</sub>, <i>etc</i>) to etch MAX phases. The properties of MXene NMs are dependent on their structures.</p><p><strong>Objective: </strong>The purpose of this review is to focus on a comprehensive and systematical survey on the preparation, structure modulation, and applications of MXene NMs in electrochemical energy storage devices, including supercapacitors, lithium-ion battery, sodium-ion battery, potassium-ion battery, and aluminum-ion battery.</p><p><strong>Methods: </strong>Extensive information related to the preparation and applications of 2D MXene NMs for electrochemical energy storage and their associated patents were collected. This review highlights the recently reported 2D MXene NMs which are used in supercapacitor and various metal ion.</p><p><strong>Results: </strong>It is found that the preparation methods have great impacts on the layer spacing and surface terminations of MXenes, consequently affecting their performance. Hence, this paper summarizes the research progress of the preparation strategies, layer spacing and surface termination modulation of MXene NMs.</p><p><strong>Conclusion: </strong>The applications of 2D MXene NMs in electrochemical energy storage are outlined. The forward-looking challenges and prospects for the development of MXenes are also proposed.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":"92-116"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9711720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Apoptotic-targeted Phytoconstitutent-loaded Antipsoriatic Nanobiocomposites. 以细胞凋亡为目标的植物成分负载型抗银屑病纳米生物复合材料的作用
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/1872210517666230201103935
Pankaj Singh Patel, Rajnish Srivastava, Sunita Panchawat
{"title":"Role of Apoptotic-targeted Phytoconstitutent-loaded Antipsoriatic Nanobiocomposites.","authors":"Pankaj Singh Patel, Rajnish Srivastava, Sunita Panchawat","doi":"10.2174/1872210517666230201103935","DOIUrl":"10.2174/1872210517666230201103935","url":null,"abstract":"<p><p>Psoriasis is an inflammatory and proliferative autoimmune dermatological disorder. It is a skin ailment that is defined by particular, drab-red or peach-pink stiff areas with silvery scales patches. Other typical characteristics include the proliferation of epidermal layer, aberrant keratinization, hyperkeratosis, increased micro capillary vascularization, and infiltration of inflammatory mediator loaded cells. Conventional pharmacotherapies currently available can only provide minor advantages. Nanomedicines based on nanotechnology can potentially improve the efficacy and safety of psoriasis medications. Apoptosis plays an important pathogenetic role in many chronic inflammatory diseases, including those of dermatological interest, in particular, regarding psoriasis. In this regard, treatments with antioxidant properties could be appropriate therapeutic options. We reviewed the available studies on the efficacy of antiapoptotic therapies in psoriasis. We'll look at phytochemicals in this review, which are natural components found in plants with antiapoptotic activity that are frequently used to treat psoriasis. For improved topical treatment, we also take into consideration the advantages of loading phytoconstituents as medicines into lipid based nanocarriers. The utilization of herbal nanomedicines in psoriasis, as well as nano delivery carrier system for phytoconstituents with improved therapeutic profiles and decreased toxicity, are the subjects of this review. The study's purpose is to find more effective herbal nanomedicines for treating psoriasis. In the treatment of psoriasis, phytoconstituents that have shown antipsoriatic potential in recent years, as well as phytoconstituents loaded based nanomedicines, have a lot of promising roles to be explored. Furthermore, very few patents have been found in the field of nanotechnology utilizing lipid-based nanocarrier system for the treatment of psoriasis. Therefore, this review greatly compels the researcher to validate the process development of lipid-based drug delivery system for the patentability of the product. This should be in a view of shifting in the applicability of the drug delivery system for general public health as a potential treatment option in psoriasis.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":"220-236"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10656806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comprehensive Review on Prospects of Polymeric Nanoparticles for Treatment of Diabetes Mellitus: Receptors-Ligands, In vitro & In vivo Studies. 聚合物纳米粒子治疗糖尿病前景综述:受体-配体、体外和体内研究。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/1872210517666230803091245
Arinjay Jain, Shilpa Dawre
{"title":"A Comprehensive Review on Prospects of Polymeric Nanoparticles for Treatment of Diabetes Mellitus: Receptors-Ligands, <i>In vitro</i> & <i>In vivo</i> Studies.","authors":"Arinjay Jain, Shilpa Dawre","doi":"10.2174/1872210517666230803091245","DOIUrl":"10.2174/1872210517666230803091245","url":null,"abstract":"<p><p>As per International Diabetes Federation Report 2022, worldwide diabetes mellitus (DM) caused 6.7M moralities and ~537M adults suffering from diabetes mellitus. It is a chronic condition due to β-cell destruction or insulin resistance that leads to insulin deficiency. This review discusses Type-1 DM and Type-2 DM pathophysiology in detail, with challenges in management and treatment. The toxicity issues of conventional drugs and insulin injections are complex to manage. Thus, there is a need for technological intervention. In recent years, nanotechnology has found a fruitful advancement of novel drug delivery systems that might potentially increase the efficacy of anti-diabetic drugs. Amongst nano-formulations, polymeric nanoparticles have been studied to enhance the bioavailability and efficacy of anti-diabetic drugs and insulin. In the present review, we summarized polymeric nanoparticles with different polymers utilized to deliver anti-diabetic drugs with <i>in vitro</i> and <i>in vivo</i> studies. Furthermore, this review also includes the role of receptors and ligands in diabetes mellitus and the utilization of receptor-ligand interaction to develop targeted nanoparticles. Additionally, we discussed the utility of nanoparticles for the delivery of phytoconstituents which aids in protecting the oxidative stress generated during diabetes mellitus. Atlast, this article also comprises of numerous patents that have been filed or granted for the delivery of antidiabetic and anticancer molecules for the treatment of diabetes mellitus and pancreatic cancer.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":"457-478"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10284198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书