A Comprehensive Review on Recent Advances and Patents of Niosomes

IF 2 4区材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY

Recent Patents on Nanotechnology Pub Date : 2023-10-10 DOI:10.2174/0118722105259776231002071218

Sushma Verma, Sakshi Saharawat

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Abstract

Abstract: Niosomes are novel, self-assembled vesicular carriers that deliver both lipophilic and hydrophilic drugs at the specific site in a targeted way, enhancing bioavailability and extending therapeutic effects. Niosomes are a versatile drug delivery system with a diverse range of applications from gene to brain-targeted delivery and they are more attractive choices than liposomes as they are efficient at biodegrading. Niosome offers several advantages over conventional drug delivery systems, including enhanced stability, and also have gained a lot of focus in natural product delivery in recent years. This review provides a comprehensive view of niosomal research and recent advancements, including classification and fabrication methods, and their role in drug delivery and targeting. The description of the rise in niosomal formulation patents around the world is also elaborated along with the natural product delivery of niosomes which has recently gained significance. Patents on novel preparation, loading, and modification techniques have enhanced the importance of niosome in the pharmaceutical industry.

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niosome的研究进展及专利综述

摘要:乳小体是一种新型的自组装囊状载体，可将亲脂性和亲水性药物靶向递送到特定部位，提高生物利用度，延长治疗效果。Niosomes是一种多功能的药物传递系统，具有从基因到脑靶向传递的多种应用，并且由于其生物降解效率高，因此比脂质体更具吸引力。Niosome与传统的药物输送系统相比具有许多优势，包括增强的稳定性，近年来在天然药物输送方面也获得了很多关注。本文综述了niosomal的研究和最新进展，包括分类和制造方法，以及它们在药物传递和靶向中的作用。对世界各地niosomal配方专利的增加的描述也与niosomal的天然产物递送一起进行了阐述，这最近具有重要意义。新的制备、装载和修饰技术的专利提高了niosome在制药工业中的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Recent Patents on Nanotechnology NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY

CiteScore

4.70

自引率

10.00%

发文量

审稿时长

3 months

期刊介绍： Recent Patents on Nanotechnology publishes full-length/mini reviews and research articles that reflect or deal with studies in relation to a patent, application of reported patents in a study, discussion of comparison of results regarding application of a given patent, etc., and also guest edited thematic issues on recent patents in the field of nanotechnology. A selection of important and recent patents on nanotechnology is also included in the journal. The journal is essential reading for all researchers involved in nanotechnology.