Journal of Medical Devices-Transactions of the Asme最新文献_第4页

Development of a Customized Mask Frame Using a 3D Facial Scan for an Airtight Seal for Disposable Surgical Face Masks 使用3D面部扫描为一次性外科口罩的气密密封定制面罩框架的开发

IF 0.9 4区医学

Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-12-16 DOI: 10.1115/1.4056506

J. Park, M. Mehrubeoglu

{"title":"Development of a Customized Mask Frame Using a 3D Facial Scan for an Airtight Seal for Disposable Surgical Face Masks","authors":"J. Park, M. Mehrubeoglu","doi":"10.1115/1.4056506","DOIUrl":"https://doi.org/10.1115/1.4056506","url":null,"abstract":"\u0000 The present study focuses on the design and development of a custom frame, using an individual's 3D custom facial scan, to improve the seal of the existing surgical masks. Three participants' facial scans with a wide range of facial dimensions were collected using a 3D hand-held scanner. During design, the contact area between the custom mask frame and the wearer's skin was determined based on an individual's 3D facial shape. To evaluate the effectiveness of the airtight seal, a qualitative fit (smell/taste) test kit and thermal image camera were utilized. When the participants wore the surgical masks without the customized mask frames to securely fit the surgical masks, the participants smelled the saccharine scent from the test kit. However, while wearing the surgical masks fitted with the custom mask frame that held the mask in place, none of the participants could smell the scent. In addition, thermal images showed ambient temperature changes in a surgical mask suggesting air leakage around the boundary of the mask, while the subject was inhaling and exhaling. The thermal images confirmed the effectiveness of the custom frame to block the inflow/outflow of air potentially carrying the virus. The developed custom mask frame will be particularly beneficial for frontline medical staff members who treat patients with infectious viruses transmitted through aerosols as part of their PPE.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45595318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and Validation of a Steerable Port Delivery Cannula System for Laser Interstitial Thermal Therapy 用于激光间质热疗的可操纵端口输送插管系统的设计与验证

IF 0.9 4区医学

Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-12-16 DOI: 10.1115/1.4056504

N. Agwu, E. Leuthardt, J. Gorlewicz

{"title":"Design and Validation of a Steerable Port Delivery Cannula System for Laser Interstitial Thermal Therapy","authors":"N. Agwu, E. Leuthardt, J. Gorlewicz","doi":"10.1115/1.4056504","DOIUrl":"https://doi.org/10.1115/1.4056504","url":null,"abstract":"\u0000 MRI (Magnetic Resonance Imaging) guided laser interstitial thermal therapy (LITT) is a procedure used for treating glioblastomas and epilepsy lesions in the brain. Current methods for placing LITT ablation probes use straight trajectories. This limits the treatment area, necessitating multiple passes of straight trajectories or risking untreated tumor margins. This work presents a port delivery cannula system (PDCS) to be integrated within existing surgical workflows of LITT, providing off-axis navigation to areas otherwise deemed inaccessible. The design of the PDCS is centered around a two-tube, Nitinol active cannula system, which delivers, places, and retracts a flexible, thermoplastic port along curved trajectories. We present the design of the PDCS system and validate it in free-space, phantom models, and ovine brain trials, with a specific focus on evaluating key parameters of port material characteristics. Eight commercial, biocompatible ports and five custom ports created using additive manufacturing were investigated. Results illustrate that ideal port characteristics include durometers between 85A-95A, a low coefficient of friction, and a wall thickness of approximately 20% of the overall port diameter. Our results also demonstrate that the PDCS system can achieve accuracies under 1mm in phantom models and 2mm in ovine tissue.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47782414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Autonomous Cricothyroid Membrane Detection and Manipulation Using Neural Networks and a Robot Arm for First-Aid Airway Management 基于神经网络和机械臂的环甲膜自主检测与操作在急救气道管理中的应用

IF 0.9 4区医学

Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-12-16 DOI: 10.1115/1.4056505

Xiao-Peng Han, Hailin Ren, Jingyuan Qi, P. Ben-Tzvi

{"title":"Autonomous Cricothyroid Membrane Detection and Manipulation Using Neural Networks and a Robot Arm for First-Aid Airway Management","authors":"Xiao-Peng Han, Hailin Ren, Jingyuan Qi, P. Ben-Tzvi","doi":"10.1115/1.4056505","DOIUrl":"https://doi.org/10.1115/1.4056505","url":null,"abstract":"\u0000 Cricothyrotomy serves as one of the most efficient surgical interventions when a patient is enduring a Can't Intubate Can't Oxygenate (CICO) scenario. However, medical background and professional training are required for the provider to establish a patent airway successfully. Motivated by robotics applications in search and rescue, this work focuses on applying artificial intelligence techniques on the precise localization of the incision site, the cricothyroid membrane (CTM), of the injured using an RGB-D camera, and the manipulation of a robot arm with reinforcement learning to reach the detected CTM keypoint. In this paper, we further improved the success rate of our previously proposed Hybrid Neural Network (HNNet) in detecting the CTM from 84.3% to 96.6%, yielding an error of less than 5mm in real-world coordinates. In addition, a separate neural network was trained to manipulate a robotic arm for reaching a waypoint with an error of less than 5mm. An integrated system that combines both the perception and the control techniques was built and experimentally validated using a human-size manikin to validate the overall concept of autonomous cricothyrotomy with an RGB-D camera and a robotic manipulator using artificial intelligence.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48808132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a Computational Framework for the Evaluation of Biodegradable Cerebral Stents with Enhanced Bending Performance 具有增强弯曲性能的可生物降解脑支架评估计算框架的开发

IF 0.9 4区医学

Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-12-16 DOI: 10.1115/1.4056507

Weiliang Shi, Chen Zhang, Ankun Xie, Kellen Mitchell, Yifei Jin, Danyang Zhao

{"title":"Development of a Computational Framework for the Evaluation of Biodegradable Cerebral Stents with Enhanced Bending Performance","authors":"Weiliang Shi, Chen Zhang, Ankun Xie, Kellen Mitchell, Yifei Jin, Danyang Zhao","doi":"10.1115/1.4056507","DOIUrl":"https://doi.org/10.1115/1.4056507","url":null,"abstract":"Cerebral aneurysm disease has extremely high mortality and morbidity, which can be efficiently treated by implanting a vascular stent. However, due to relatively poor flexibility and biodegradability, current vascular stents still cause some life-threatening complications. Thus, it is of great significance to develop new biodegradable cerebral stents (BCSs) with enhanced flexibility for improving the prognosis of cerebral aneurysm disease. In this work, a flexibility-enhanced BCS architecture has been investigated and designed. Both numerical simulation and experiments have been performed to demonstrate the potential clinical application of the proposed BCSs. First, the effects of the structural parameters on the flexibility have been analyzed by finite element simulation. Then, the mechanical properties of the proposed BCSs have been characterized via both numerical simulation and experiments and compared to those of two representative commercial stents for demonstrating the flexibility and radial stiffness of the proposed design. The knowledge from this work provides a new design methodology.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43710134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design of a Novel Tendon-Sheath-Driven Upper Limb Exoskeleton for Assisting Surgeon Performing Microlaryngoscopic Surgery 一种新型肌腱鞘驱动的上肢外骨骼的设计，用于辅助外科医生进行喉镜手术

IF 0.9 4区医学

Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-11-24 DOI: 10.1115/1.4056319

Zhengyu Wang, Wenjun Song, Sen Qian, Daoming Wang, Zirui Jia, Xiang Yu

{"title":"Design of a Novel Tendon-Sheath-Driven Upper Limb Exoskeleton for Assisting Surgeon Performing Microlaryngoscopic Surgery","authors":"Zhengyu Wang, Wenjun Song, Sen Qian, Daoming Wang, Zirui Jia, Xiang Yu","doi":"10.1115/1.4056319","DOIUrl":"https://doi.org/10.1115/1.4056319","url":null,"abstract":"\u0000 Microlaryngoscopic surgery is a type of laryngeal surgery performed by surgeons using microsurgical instruments under the observation of a specially designed laryngoscope. While performing a microlaryngoscopic operation, the surgeons must maintain their arm position for a long time, which can cause arm soreness and affect the accuracy of the operation. In this study, a tendon-sheath-driven upper limb auxiliary exoskeleton (TULAE) is proposed and developed. The flexible cables are compressed by a wave-shaped pressing mechanism to fix the TULAE's rotating joints. The TULAE can assist surgeons in laryngoscopy operations by providing suitable support for their arms to reduce the surgical risks caused by muscle fatigue. The TULAE has 4 degrees of freedom (DOF) on each arm. The shoulder flexion/extension, shoulder abduction/adduction and elbow internal rotation/external rotation can be fixed by the control box. The shoulder internal rotation/ external rotation is a passive DOF obtained using hinges. The TULAE's shoulder, upper arm and forearm links are designed with lengths adjustable to accommodate wearers of different heights and weights. A large-scale but risk-free workspace is analyzed through rigid body kinematics using the spinor method. The control hardware of the TULAE is developed based on the open-source Arduino board. Finally, the experimental results show that this TULAE can significantly reduce the range of wrists shaking and assist surgeons in laryngoscopy surgery.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42307728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Portable, Vacuum-Operated, and Purely Mechanical Device for Extracting Feces by Suction to Cure Chronic Anal Fissures 一种便携式、真空操作、纯机械抽吸粪便治疗慢性肛裂的装置

IF 0.9 4区医学

Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-11-15 DOI: 10.1115/1.4056251

Riaz Ur Rehman Mohammed, Vedad Bassari, Richard Rasmussen, B. Terry

{"title":"A Portable, Vacuum-Operated, and Purely Mechanical Device for Extracting Feces by Suction to Cure Chronic Anal Fissures","authors":"Riaz Ur Rehman Mohammed, Vedad Bassari, Richard Rasmussen, B. Terry","doi":"10.1115/1.4056251","DOIUrl":"https://doi.org/10.1115/1.4056251","url":null,"abstract":"\u0000 An anal fissure is a common anorectal problem that affects men and women of all age groups. It develops from an acute phase that presents as a linear or oval tear in the anoderm and may progress to a more complex chronic stage due to poor healing. Routine defecation causes overstretching of the anoderm and deepens the scar, setting up a positive feedback loop that keeps the fissure from healing. Existing treatments can be invasive, expensive, and may induce side effects. Here we present a novel vacuum-operated mechanical device to extract feces via suction. The device is designed to solve the problem of anodermal stretching by assisting in defecation. The device was tested in vitro on a benchtop model of the rectum and in vivo on pigs. In vitro tests showed that the device could hold a vacuum for 12 h with negligible leakage. Further, the device could extract simulated human feces at a flowrate of 32 mL/s. In vivo tests on pigs showed that the device did not cause any trauma to the rectal wall, thus demonstrating its safety. Our results highlight the potential of this novel platform to circumvent the problem of anodermal stretching and improve the healing rate of anal fissures.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44062213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of ANN to Nucleic Acid Analysis: Accurate Discrimination for Untypical Real-Time Fluorescence Curves with High Specificity and Sensitivity 人工神经网络在核酸分析中的应用：高特异性、高灵敏度的非典型实时荧光曲线的精确判别

IF 0.9 4区医学

Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-11-08 DOI: 10.1115/1.4056150

Guijun Miao, Xiaodan Jiang, Yunping Tu, Lulu Zhang, Duli Yu, Shizhi Qian, Xianbo Qiu

{"title":"Application of ANN to Nucleic Acid Analysis: Accurate Discrimination for Untypical Real-Time Fluorescence Curves with High Specificity and Sensitivity","authors":"Guijun Miao, Xiaodan Jiang, Yunping Tu, Lulu Zhang, Duli Yu, Shizhi Qian, Xianbo Qiu","doi":"10.1115/1.4056150","DOIUrl":"https://doi.org/10.1115/1.4056150","url":null,"abstract":"\u0000 As a division of polymerase chain reaction (PCR), convective PCR (CPCR) is able to achieve highly efficient thermal cycling based on free thermal convection with pseudo-isothermal heating, which could be beneficial to point-of-care (POC) nucleic acid analysis. Similar to traditional PCR or isothermal amplification, due to a couple of issues, e.g., reagent, primer design, reactor, reaction dynamics, amplification status, temperature and heating condition, and other reasons, in some cases of CPCR tests, untypical real-time fluorescence curves with positive or negative tests will show up. Especially, when parts of the characteristics between untypical low-positive and negative tests are mixed together, it is difficult to discriminate between them using traditional cycle threshold (Ct) value method. To handle this issue which may occur in CPCR, traditional PCR or isothermal amplification, as an example, instead of using complicated mathematical modeling and signal processing strategy, an artificial intelligence (AI) classification method with artificial neural network (ANN) modeling is developed to improve the accuracy of nucleic acid detection. It has been proven that both the detection specificity and sensitivity can be significantly improved even with a simple ANN model. It can be estimated that, the developed method based on AI modeling can be adopted to solve similar problem with PCR, or isothermal amplification methods.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48058786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Design and Evaluation of Self-Cooling Electrodes for Radiofrequency Intestinal Anastomosis 射频肠吻合自冷电极的设计与评价

IF 0.9 4区医学

Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-10-18 DOI: 10.1115/1.4056008

Wanli Yue, Haipo Cui, Chengli Song, Liangyong Tu, Jingcheng Lang, Wenhui Yan, Yingxi Lu

{"title":"Design and Evaluation of Self-Cooling Electrodes for Radiofrequency Intestinal Anastomosis","authors":"Wanli Yue, Haipo Cui, Chengli Song, Liangyong Tu, Jingcheng Lang, Wenhui Yan, Yingxi Lu","doi":"10.1115/1.4056008","DOIUrl":"https://doi.org/10.1115/1.4056008","url":null,"abstract":"\u0000 Colorectal cancer is a common malignant tumor in the gastrointestinal tract. Resection of the cancerous site and anastomosis of the residual intestine is the preferred radical treatment for colorectal cancer. In particular, radiofrequency energy anastomosis of the residual intestine is being increasingly used in clinical practice. To improve the quality of anastomosis, reduce the thermal damage of tissue near the anastomosis area, and avoid foreign body residue in this area, we propose a self-cooling eversion-type radiofrequency-energy intestinal anastomosis electrode, which is analyzed through simulations and evaluated experimentally for welding intestinal tissue. For radiofrequency energy power of 160 W, anastomosis time of 13.2 s, and pressure of 154 kPa, the disconnected intestinal tissues can be anastomosed using the proposed electrode. The average burst pressure of the anastomotic orifice is 43.86 mmHg. During welding, the temperature of the normal saline at the outlet is 6.8 °C higher than that at the inlet, indicating that the use of circulating normal saline as the conductive and cooling medium can dissipate part of the heat generated by welding and reduce heat accumulation, thereby reducing thermal damage of biological tissue near the welding area. Overall, the proposed electrode may contribute to the recovery of postoperative intestinal function by enabling a novel strategy for clinical intestinal anastomosis induced by radiofrequency energy.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47050408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and Evaluation of a High-Performance, Low-Cost Prosthetic Foot for Developing Countries 一种适用于发展中国家的高性能、低成本假肢足的设计与评价

IF 0.9 4区医学

Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-10-13 DOI: 10.1115/1.4055967

W. Johnson, Victor Prost, Pooja Mukul, A. Winter

{"title":"Design and Evaluation of a High-Performance, Low-Cost Prosthetic Foot for Developing Countries","authors":"W. Johnson, Victor Prost, Pooja Mukul, A. Winter","doi":"10.1115/1.4055967","DOIUrl":"https://doi.org/10.1115/1.4055967","url":null,"abstract":"\u0000 A novel, high-performance, cosmetic, rugged, appropriately-costed, mass-manufacturable prosthetic foot for use in low-income countries was designed and field tested. This ruggedized foot was created to accommodate the unique economic, environmental, and cultural requirements for users in India. A previous prototype that enabled able-bodied like gait was modified to include a durable cosmetic cover without altering the tuned stiffness of the overall foot. After undergoing mechanical benchtop testing, the foot was distributed to prosthesis users in India to for at least 5 months. Afterwards, participants underwent clinical tests to evaluate walking performance, and additional benchtop testing was performed on the field-tested feet to identify changes in performance. The ruggedized foot endured one million fatigue cycles without failure and demonstrated the desired stiffness properties. Subjects walked significantly faster (0.14 m/s) with the ruggedized foot compared to the Jaipur foot, and the feet showed no visible sign of damage after months of use. Additionally, the field-tested feet showed little difference in stiffness from a set of unused controls. Anecdotal feedback from the participants indicated that the foot improved their speed and/or walking effort, but may benefit from more degrees of freedom about the ankle. The results suggest that the foot fulfills its design requirements; however, further field testing is required with more participants over a longer period to make sure the foot is suitable for use in developing countries.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41642730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Experimental Study of Feasibility of a Mini-Invasive Fixator for Rib Osteosynthesis 微创肋骨骨固定器可行性的实验研究

IF 0.9 4区医学

Journal of Medical Devices-Transactions of the Asme Pub Date : 2022-10-05 DOI: 10.1115/1.4055861

L. Puglisi, M. Ceccarelli, V. Ambrogi

引用次数: 0