Athanasios Rempakos, Pranathi Pilla, Michaella Alexandrou, Deniz Mutlu, Dimitrios Strepkos, Pedro E P Carvalho, Ozgur Selim Ser, Ali Bahbah, Amit Amin, Anand Prasad, Lorenzo Azzalini, Luiz F Ybarra, Olga C Mastrodemos, Bavana V Rangan, Ahmed Al-Ogaili, Sandeep Jalli, M Nicholas Burke, Yader Sandoval, Emmanouil S Brilakis
{"title":"Artificial intelligence for chronic total occlusion percutaneous coronary interventions.","authors":"Athanasios Rempakos, Pranathi Pilla, Michaella Alexandrou, Deniz Mutlu, Dimitrios Strepkos, Pedro E P Carvalho, Ozgur Selim Ser, Ali Bahbah, Amit Amin, Anand Prasad, Lorenzo Azzalini, Luiz F Ybarra, Olga C Mastrodemos, Bavana V Rangan, Ahmed Al-Ogaili, Sandeep Jalli, M Nicholas Burke, Yader Sandoval, Emmanouil S Brilakis","doi":"10.25270/jic/25.00089","DOIUrl":"https://doi.org/10.25270/jic/25.00089","url":null,"abstract":"<p><p>Artificial intelligence (AI) has become pivotal in advancing medical care, particularly in interventional cardiology. Recent AI developments have proven effective in guiding advanced procedures and complex decisions. The authors review the latest AI-based innovations in the diagnosis of chronic total occlusions (CTO) and in determining the probability of success of CTO percutaneous coronary intervention (PCI). Neural networks and deep learning strategies were the most commonly used algorithms, and the models were trained and deployed using a variety of data types, such as clinical parameters and imaging. AI holds great promise in facilitating CTO PCI.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tsun-Ho Lam, Chun-Ka Wong, Cheuk-Wing Jonathan Lee, Hay-Son Robin Chen, Ka-Chun Un
{"title":"Transcatheter closure of right coronary cusp aneurysm-to-right ventricle paravalvular leak in a patient with complex congenital heart disease.","authors":"Tsun-Ho Lam, Chun-Ka Wong, Cheuk-Wing Jonathan Lee, Hay-Son Robin Chen, Ka-Chun Un","doi":"10.25270/jic/25.00106","DOIUrl":"https://doi.org/10.25270/jic/25.00106","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Richard Casazza, Bilal Malik, Arsalan Hashmi, Joshua Fogel, Enrico Montagna, Darren Gibson, Andres Palacio, Habiba Beginyazova, Robert Frankel, Jacob Shani
{"title":"Ocular radiation exposure of the primary operator performing selective coronary angiography from a radial artery approach.","authors":"Richard Casazza, Bilal Malik, Arsalan Hashmi, Joshua Fogel, Enrico Montagna, Darren Gibson, Andres Palacio, Habiba Beginyazova, Robert Frankel, Jacob Shani","doi":"10.25270/jic/25.00074","DOIUrl":"https://doi.org/10.25270/jic/25.00074","url":null,"abstract":"<p><strong>Background: </strong>Radiation exposure is one of the most adverse occupational hazards faced by interventional cardiologists. The lens of the eye is considered highly radiosensitive. The left eye (LE) is at considerably more risk of radiation-induced cataracts than the right eye (RE) due to its proximity to the radiation source during cardiac catheterization.</p><p><strong>Methods: </strong>This single-center retrospective study (n = 534) assessed the cumulative radiation (CR) exposure in microsieverts (μSv) and the normalized radiation exposure (CR/DAP) to the LE and RE of the primary operator when using a radial artery approach.</p><p><strong>Results: </strong>In the whole sample, median CR (LE: 3 vs RE: 1, P less than .001) and median CR/DAP (LE: 0.11 vs RE: 0.03, P les than .001) were higher for the LE than the RE. This same pattern occurred in separate analyses of both radial artery approaches, regardless of patient sex, height, or body mass index.</p><p><strong>Conclusions: </strong>Radiation exposure to the LE compared with the RE of interventional cardiologists is significantly more during selective coronary angiography using a radial artery approach. The authors recommend the use of radioprotective glasses in conjunction with an optimally placed ceiling-mounted shield to minimize ocular radiation exposure.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coronary artery aneurysm with thrombosis.","authors":"Di Huang, Li Zhu","doi":"10.25270/jic/25.00090","DOIUrl":"https://doi.org/10.25270/jic/25.00090","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Deniz Mutlu, Dimitrios Strepkos, Pedro Ep Carvalho, Michaella Alexandrou, Ahmed Al-Ogaili, Sandeep Jalli, Khaldoon Alaswad, Farouc A Jaffer, Rhian Davies, Paul Poommipanit, Jarrod Frizzel, Basem Elbarouni, Jaikirshan J Khatri, Sevket Gorgulu, Omer Goktekin, Ramazan Ozdemir, Mahmut Uluganyan, Ahmed ElGuindy, Yasser Sadek, Yousif Ahmed, Mir B Basir, Leah Raj, Luiz Ybarra, Bilal Murad, Bavana V Rangan, Olga C Mastrodemos, Lorenzo Azzalini, Yader Sandoval, M Nicholas Burke, Emmanouil S Brilakis
{"title":"Use of the Ostial Flash balloon in aorto-ostial chronic total occlusion percutaneous coronary intervention.","authors":"Deniz Mutlu, Dimitrios Strepkos, Pedro Ep Carvalho, Michaella Alexandrou, Ahmed Al-Ogaili, Sandeep Jalli, Khaldoon Alaswad, Farouc A Jaffer, Rhian Davies, Paul Poommipanit, Jarrod Frizzel, Basem Elbarouni, Jaikirshan J Khatri, Sevket Gorgulu, Omer Goktekin, Ramazan Ozdemir, Mahmut Uluganyan, Ahmed ElGuindy, Yasser Sadek, Yousif Ahmed, Mir B Basir, Leah Raj, Luiz Ybarra, Bilal Murad, Bavana V Rangan, Olga C Mastrodemos, Lorenzo Azzalini, Yader Sandoval, M Nicholas Burke, Emmanouil S Brilakis","doi":"10.25270/jic/24.00263","DOIUrl":"10.25270/jic/24.00263","url":null,"abstract":"<p><strong>Background: </strong>The use of the Ostial Flash balloon (Ostial Corporation) has received limited study in aorto-ostial chronic total occlusion (CTO) percutaneous coronary artery intervention (PCI).</p><p><strong>Methods: </strong>The authors evaluated the outcomes of Ostial Flash balloon use in a large CTO-PCI registry (PROGRESS-CTO, NCT02061436).</p><p><strong>Results: </strong>The Ostial Flash balloon was used in 54 of 907 aorto-ostial CTO PCIs in 905 patients (6.0%). The mean patient age was 65.1 ± 10.7 and 80.6% were men, with a high prevalence of diabetes mellitus, hypertension, prior PCI, and prior myocardial infarction. The mean occlusion length was 40.5 ± 25.1 mm, 52.2% had moderate to severe calcification, and the mean Japanese-CTO score was 2.8 ± 1.1. Lesions treated with the Ostial Flash balloon were more frequently located in the right aorto-ostium (79.6% vs 66.0%, P = .002). In the Ostial Flash group, the most common successful CTO crossing technique was antegrade wiring (46.3%), followed by the retrograde approach (40.7%); intravascular imaging was used in 61.1% of cases. Technical success (92.6% vs 87.9%, P = .300) and the incidence of major adverse cardiac events (MACE) (5.6% vs 3.6%, P = .450) was similar in the Ostial Flash vs non-Ostial Flash patients, respectively. In multivariable analysis, PCI of proximal right coronary artery CTOs was independently associated with use of the Ostial Flash balloon (odds ratio 2.2; 95% CI, 1.1-4.8; P = .036).</p><p><strong>Conclusions: </strong>The Ostial Flash balloon is infrequently used in aorto-ostial CTO PCI. Although there were no differences in MACE with use of the balloon, randomized controlled trials are needed to determine its effectiveness.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maksymilian P Opolski, Antoni Zysk, Wojciech J Skorupski, Artur Debski, Adam Witkowski
{"title":"Randomized comparison of a Gladius first versus standard antegrade wiring strategy for crossing coronary chronic total occlusions: the Gladius first trial.","authors":"Maksymilian P Opolski, Antoni Zysk, Wojciech J Skorupski, Artur Debski, Adam Witkowski","doi":"10.25270/jic/24.00316","DOIUrl":"10.25270/jic/24.00316","url":null,"abstract":"<p><strong>Objectives: </strong>Antegrade wiring (AW) is the most common coronary chronic total occlusion (CTO) crossing strategy and usually relies upon stepwise guidewire escalation starting from the low tip-load polymer-jacketed wire (standard guidewire escalation). The authors aimed to investigate whether the upfront use of intermediate tip-load polymer-jacketed guidewire translates into improved procedural outcomes of CTO percutaneous coronary intervention (PCI).</p><p><strong>Methods: </strong>The Gladius First trial was a single-center, investigator-initiated, randomized, prospective trial. The primary endpoint was the time of AW strategy, while the secondary endpoints included CTO crossing success, procedural success, contrast volume, radiation dose, total procedural time, safety parameters, equipment use, and cost.</p><p><strong>Results: </strong>Between 2021 and 2023, 69 patients with 70 CTO lesions (J-CTO score ≥ 1) were randomized to either upfront Gladius EX (Asahi Intecc) AW (n = 33) or standard guidewire escalation AW (n = 37). The clinical and angiographic characteristics of 2 groups were similar. Overall, CTO crossing and procedural success were 92.9% and 90%, respectively, and similar between groups. Although the AW time was significantly shorter in the Gladius AW group (10 minutes; IQR: 4-16 minutes) than in the standard AW group (21 minutes; IQR: 11-28 minutes, P = .001), the total procedural time, procedural success, safety parameters, resource use, and equipment cost were similar between groups.</p><p><strong>Conclusions: </strong>Compared with standard guidewire escalation, the upfront use of the Gladius guidewire was associated with a shorter AW time but similar total procedural time, procedural success, safety, and cost.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aaron Lee, Dorothy Jung, Mohammad Ahmed, Jonathan Norton, Francois Kaleta, Samer Muallem, Maulin Patel, Moses Mathur, Mark Kozak, Ian C Gilchrist, Chad J Zack
{"title":"Complications associated with use of the Wolverine cutting balloon: insights from the Manufacturer and User Facility Device Experience (MAUDE) database.","authors":"Aaron Lee, Dorothy Jung, Mohammad Ahmed, Jonathan Norton, Francois Kaleta, Samer Muallem, Maulin Patel, Moses Mathur, Mark Kozak, Ian C Gilchrist, Chad J Zack","doi":"10.25270/jic/24.00300","DOIUrl":"10.25270/jic/24.00300","url":null,"abstract":"<p><strong>Objectives: </strong>The Wolverine cutting balloon (CB) (Boston Scientific) is a specialized balloon catheter with microsurgical blades that is used for balloon-resistant lesions. The Manufacturer and User Facility Device Experience (MAUDE) database serves as a repository for reports of medical device complications. The aim of this study was to analyze complications associated with CB use during percutaneous coronary intervention in real-world contemporary practice.</p><p><strong>Methods: </strong>The MAUDE database was searched from January 1, 2020 through December 31, 2023 for reports of complications associated with CB use. Data from individual reports were extracted for analysis.</p><p><strong>Results: </strong>The final analysis included 2278 complications, of which 97.3% (n = 2216) were associated with device malfunction, 2.4% (n = 55) were associated with patient injury, and 0.3% (n = 7) were associated with patient death. The most common complication overall was balloon rupture (n = 1847), while the most common complication associated with patient injury or death was device entrapment (n = 33). The median number of inflations was significantly higher for complications associated with patient injury or death (3 [IQR 1-8]) compared with complications associated with device malfunction (1[IQR 1-2]) (P = .0035). The median maximum inflation pressure was significantly higher for complications associated with patient injury or death (12 [IQR 11-15] atm) compared with complications associated with device malfunction (8 [IQR 6-10] atm) (P = .0001).</p><p><strong>Conclusions: </strong>Overall, 2.7% of reported complications were associated with patient injury or death. The most common complication overall was balloon rupture. Device entrapment was the most common complication among reports associated with patient injury or death. Higher inflation pressures and greater number of inflations may be associated with adverse outcomes.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Outcomes of a transapical edge-to-edge repair system in secondary mitral regurgitation.","authors":"Qinchun Jin, Wei Li, Jianing Fan, Dawei Lin, Zilong Wen, Yuan Zhang, Wei Lai, Wenzhi Pan, Daxin Zhou, Junbo Ge","doi":"10.25270/jic/24.00234","DOIUrl":"10.25270/jic/24.00234","url":null,"abstract":"<p><strong>Objectives: </strong>The ValveClamp system (Hanyu Medical Technology) is a novel transcatheter edge-to-edge repair (TEER) system designed for ease of operation; however, there is a lack of data on its application in secondary mitral regurgitation (SMR). The authors report the mid-term outcomes of TEER using the ValveClamp system in SMR.</p><p><strong>Methods: </strong>The study prospectively analyzed consecutive severe SMR patients who underwent transapical ValveClamp implantation at 10 Chinese centers. The enrolled patients were categorized into atrial SMR (aSMR) and ventricular SMR (vSMR) groups. Clinical and echocardiographic outcomes were evaluated at baseline and at follow-up.</p><p><strong>Results: </strong>A total of 19 aSMR and 24 vSMR patients were enrolled. Technical success was achieved in 100% of the patients and the overall 30-day device success rate was 88.37%. At 1 year, sustained MR reduction to less than or equal to 1+ was achieved in 76.47% of aSMR cases and 77.27% of vSMR cases, and positive reverse left cardiac remodeling was observed. The estimated overall 1-year survival and HF rehospitalization rates for aSMR and vSMR were 83.33% and 83.59%, respectively (log rank P = .98), and improvement of New York Heart Association functional class and Kansas City Cardiomyopathy Questionnaire score were observed in both groups. In multivariable logistic analysis, a lower leaflet-to-annulus index (LAI) (odds ratio [OR], 0.021; 95% CI, 0.001-0.042; P = .02) and a narrow MR jet type (OR, 12.029; 95% CI, 1.530-94.592-0.990; P = .02) were independently associated with a higher incidence of a residual MR of at least 2+ at 3 months after TEER.</p><p><strong>Conclusions: </strong>TEER using the ValveClamp system is a safe and feasible therapeutic option for patients with SMR regardless of MR etiology. A lower LAI and a narrow MR jet type were independent predictors of residual MR at follow-up.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}