Giovanni Lorenzoni, Cristiana Denurra, Pierluigi Merella, Giuseppe Talanas, Gavino Casu
{"title":"Double culprit lesion: a challenging case of simultaneous coronary thrombotic occlusion.","authors":"Giovanni Lorenzoni, Cristiana Denurra, Pierluigi Merella, Giuseppe Talanas, Gavino Casu","doi":"10.25270/jic/25.00110","DOIUrl":"10.25270/jic/25.00110","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ozgur Selim Ser, Deniz Mutlu, Dimitrios Strepkos, Pedro E Carvalho, Michaella Alexandrou, Eleni Kladou, Olga Mastrodemos, Silvia Moscardelli, Primero Ng, Bavana V Rangan, Jas D Sara, Sandeep Jalli, Konstantinos Voudris, Lorenzo Azzalini, Yader Sandoval, M Nicholas Burke, Emmanouil S Brilakis
{"title":"Clinical, procedural, and follow-up outcomes of percutaneous coronary intervention-related stroke: insight from the PROGRESS-COMPLICATIONS registry.","authors":"Ozgur Selim Ser, Deniz Mutlu, Dimitrios Strepkos, Pedro E Carvalho, Michaella Alexandrou, Eleni Kladou, Olga Mastrodemos, Silvia Moscardelli, Primero Ng, Bavana V Rangan, Jas D Sara, Sandeep Jalli, Konstantinos Voudris, Lorenzo Azzalini, Yader Sandoval, M Nicholas Burke, Emmanouil S Brilakis","doi":"10.25270/jic/25.00157","DOIUrl":"10.25270/jic/25.00157","url":null,"abstract":"<p><strong>Background: </strong>Stroke is an infrequent but potentially severe complication of percutaneous coronary intervention (PCI).</p><p><strong>Methods: </strong>The authors describe the clinical features, angiographic characteristics, and procedural and follow-up outcomes of PCI-related stroke in the PROGRESS-COMPLICATIONS registry.</p><p><strong>Results: </strong>Of 22 503 patients who underwent PCI at 2 tertiary care centers between 2016 and 2023, 157 (0.7%) had PCI-related stroke: 10 (6.4%) had hemorrhagic stroke while 147 (93.6%) had ischemic stroke. The mean age of the stroke patients was 70 ± 11 years; 63.1% were men, 25.2% had prior heart failure, 71.0% had diabetes mellitus, 85.4% had hypertension, and 36.6% had chronic kidney disease. Radial access was used in 39.5% of the patients; 31.1% of stroke patients presented with ST-segment elevation myocardial infarction (STEMI), 49.7% with non-STEMI, and 14.6% with stable angina. The target lesions were complex: 47.1% were bifurcations, 63.7% had moderate to severe calcification, and 56.0% had thrombus. The mean minimum activated clotting time of the stroke patients was 214 (165, 245) seconds. Technical success was 93%. A mechanical circulatory support device was utilized in 31 (20%) of the patients, and 17 (10.8%) presented with cardiogenic shock. Hypotension during the procedure occurred in 36 patients (22.9%), bleeding occurred in 37 (23.6), and in-hospital mortality was 13.7%. During a median follow-up of 32 months, 48.3% of the patients had follow-up major adverse cardiovascular events (MACE) and 24.5% died.</p><p><strong>Conclusions: </strong>Stroke is an infrequent but severe complication of PCI, associated with high mortality and MACE. Most periprocedural strokes were ischemic.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Richard Casazza, Bilal Malik, Arsalan Hashmi, Joshua Fogel, Enrico Montagna, Darren Gibson, Andres Palacio, Habiba Beginyazova, Robert Frankel, Jacob Shani
{"title":"Ocular radiation exposure of the primary operator performing selective coronary angiography from a radial artery approach.","authors":"Richard Casazza, Bilal Malik, Arsalan Hashmi, Joshua Fogel, Enrico Montagna, Darren Gibson, Andres Palacio, Habiba Beginyazova, Robert Frankel, Jacob Shani","doi":"10.25270/jic/25.00074","DOIUrl":"10.25270/jic/25.00074","url":null,"abstract":"<p><strong>Background: </strong>Radiation exposure is one of the most adverse occupational hazards faced by interventional cardiologists. The lens of the eye is considered highly radiosensitive. The left eye (LE) is at considerably more risk of radiation-induced cataracts than the right eye (RE) due to its proximity to the radiation source during cardiac catheterization.</p><p><strong>Methods: </strong>This single-center retrospective study (n = 534) assessed the cumulative radiation (CR) exposure in microsieverts (μSv) and the normalized radiation exposure (CR/DAP) to the LE and RE of the primary operator when using a radial artery approach.</p><p><strong>Results: </strong>In the whole sample, median CR (LE: 3 vs RE: 1, P less than .001) and median CR/DAP (LE: 0.11 vs RE: 0.03, P les than .001) were higher for the LE than the RE. This same pattern occurred in separate analyses of both radial artery approaches, regardless of patient sex, height, or body mass index.</p><p><strong>Conclusions: </strong>Radiation exposure to the LE compared with the RE of interventional cardiologists is significantly more during selective coronary angiography using a radial artery approach. The authors recommend the use of radioprotective glasses in conjunction with an optimally placed ceiling-mounted shield to minimize ocular radiation exposure.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pooja Mishra, Jonathan Rosenberg, Verghese Mathew, Justin Levisay, Mark J Ricciardi, Arman Qamar
{"title":"Coronary intravascular lithotripsy for acute stent underexpansion: a case series.","authors":"Pooja Mishra, Jonathan Rosenberg, Verghese Mathew, Justin Levisay, Mark J Ricciardi, Arman Qamar","doi":"10.25270/jic/25.00293","DOIUrl":"https://doi.org/10.25270/jic/25.00293","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Leadless pacemaker placement through the subclavian vein: an alternative to the femoral route.","authors":"Leili Pourafkari, Jeong Hwan J Kim, Ali Sovari","doi":"10.25270/jic/25.00257","DOIUrl":"https://doi.org/10.25270/jic/25.00257","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yash Prakash, Eric J Kim, Ranbir Singh, Lakshay Chopra, Akarsh Sharma, Eileen Galvani, Thomas Hanlon, Ankita Naraparaju, Carlo Mannina, Oludamilola Akinmolayemi, Annapoorna S Kini, Samin K Sharma, Stamatios Lerakis
{"title":"Aortic valve calcification alone identifies transcatheter aortic valve replacement benefit in classical low-flow, low-gradient aortic stenosis.","authors":"Yash Prakash, Eric J Kim, Ranbir Singh, Lakshay Chopra, Akarsh Sharma, Eileen Galvani, Thomas Hanlon, Ankita Naraparaju, Carlo Mannina, Oludamilola Akinmolayemi, Annapoorna S Kini, Samin K Sharma, Stamatios Lerakis","doi":"10.25270/jic/25.00290","DOIUrl":"https://doi.org/10.25270/jic/25.00290","url":null,"abstract":"<p><p>Aortic valve calcification (AVC) is a guideline-endorsed diagnostic tool in low-flow, low-gradient (LFLG) aortic stenosis (AS), but its prognostic value across LFLG subtypes remains debated. In this retrospective cohort of 457 patients undergoing transcatheter aortic valve replacement (TAVR), severe AVC was associated with significantly fewer heart failure rehospitalizations in classical LFLG AS (adjusted hazard ratio [HR], 0.41; P = .023) but not in paradoxical LFLG AS (adjusted HR, 0.76; P = .422). AVC also correlated with true-severe AS when dobutamine stress echocardiography (DSE) was performed. These findings suggest that AVC alone can identify classical LFLG AS patients likely to benefit from TAVR, even when DSE results are unavailable or inconclusive.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlo Briguori, Luca Paolucci, Mario Scarpelli, Antonietta Di Iorio, Valeria Cavaliere, Amelia Focaccio, Francesca De Micco, Daniele Maselli
{"title":"Plug-based vascular closure device in transfemoral transcatheter aortic valve implantation.","authors":"Carlo Briguori, Luca Paolucci, Mario Scarpelli, Antonietta Di Iorio, Valeria Cavaliere, Amelia Focaccio, Francesca De Micco, Daniele Maselli","doi":"10.25270/jic/25.00181","DOIUrl":"https://doi.org/10.25270/jic/25.00181","url":null,"abstract":"<p><strong>Objectives: </strong>Failure of vascular closure device (VCD) is the most common cause of access-site vascular complications in transfemoral transcatheter aortic valve implantation (TAVI). The authors sought to determine if the systematic use of arteriotomy-site ballooning with concomitant manual compression following the delivery of a plug-based VCD (MANTA, Teleflex) can optimize toggle-plug assembly apposition to the common femoral artery (CFA) wall and improve the final hemostatic efficacy.</p><p><strong>Methods: </strong>In this prospective, observational, single-center study, 323 consecutive patients undergoing transfemoral TAVI from October 2021 to December 2024 underwent access closure with the MANTA VCD. The primary endpoints were VCD failure rate, predictors of VCD failure, and access-site and access-related major and minor vascular complications, according to the Valve Academic Research Consortium-3 definition.</p><p><strong>Results: </strong>VCD failure occurred in 12 (3.7%) patients (Failure group). The independent predictors of failure were minimum CFA diameter and patient risk as assessed by the Society of Thoracic Surgeons Predicted Risk of Mortality score. Receiver operating characteristic analysis showed CFA minimum diameter with an area under the curve of 0.77 (0.69-0.86, P less than .001); the best cutoff was 6.30 mm (sensitivity 83%; specificity 59%; positive predictive value 7%; negative predictive value 99%). Access-site vascular complications occurred in 21 (6.5%) patients.</p><p><strong>Conclusions: </strong>The systematic use of arteriotomy-site ballooning plus concomitant manual compression following MANTA VCD delivery should be considered to improve the final hemostatic efficacy. This device should be avoided when dealing with small (less than 6.3 mm) CFA diameters.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fabien Picard, Vincent Pham, Sophia El Harrrouchi, Pierre Brami, Vincent Millien, Ludovic Meunier
{"title":"Drug-coated balloon strategy following intravascular lithotripsy to treat coronary de novo lesion: mid-term clinical outcomes of a preliminary experience.","authors":"Fabien Picard, Vincent Pham, Sophia El Harrrouchi, Pierre Brami, Vincent Millien, Ludovic Meunier","doi":"10.25270/jic/25.00183","DOIUrl":"https://doi.org/10.25270/jic/25.00183","url":null,"abstract":"<p><strong>Objectives: </strong>The management of patients with calcified de novo lesions remains a major clinical challenge even in the era of drug-eluting stents (DES). Drug-coated balloon (DCB) therapy has emerged as an alternative to DES to treat de novo lesions. Nevertheless, the management of calcified lesions using intravascular lithotripsy (IVL) combined with DCB to treat de novo lesions has not been investigated. The authors report the short-term results of our preliminary experience with this novel approach.</p><p><strong>Methods: </strong>The authors conducted a multicenter retrospective study of 14 patients who underwent percutaneous coronary intervention for de novo lesions treated with IVL followed by DCB in 3 centers between September 2023 and July 2024.</p><p><strong>Results: </strong>The mean age of the patients was 69 years, and 71% were male. At 30 days, 1 patient experienced non-cardiac death. No lesion site thrombosis, target lesion revascularization (TLR), or cardiac death occurred at the 30-day follow-up. At the 6-month follow-up, 2 (14.3%) patients experienced TLR.</p><p><strong>Conclusions: </strong>This real-world data using IVL followed by DCB (in cases of acceptable lesion preparation) in patients with de novo calcified coronary lesions suggest that this strategy is feasible and appears to have an acceptable target lesion failure rate at mid-term follow-up. This proof of concept could be hypothesis-generating for larger studies.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Walls within walls: a tale of twin aortic stenosis in type II familial hypercholesterolemia.","authors":"Anbhigya Kumar Arya, Krishna Prasad Akkineni, Shrividya Rao, Saurabh Kumar Singh, Souvik Sardar, Anwar Hussain Ansari, Devesh Kumar","doi":"10.25270/jic/25.00267","DOIUrl":"https://doi.org/10.25270/jic/25.00267","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}