Marios Tsourous, Dimitrios Strepkos, Theodoros Vichos, Michaella Alexandrou, Pedro E P Carvalho, Ahmet Akyel, Parth Desai, Ayman Fath, Sophie Macy, James W Choi, Sevket Gorgulu, Farouc A Jaffer, Raj Chandwaney, Khaldoon Alaswad, Mir B Basir, Lorenzo Azzalini, Dmitrii Khelimskii, Oleg Krestyaninov, Laura Young, Omer Goktekin, Konstantinos Voudris, Noah N Williford, Angie S Lobo, Yader Sandoval, Emmanouil S Brilakis
{"title":"Chronic total occlusion percutaneous coronary interventions in dialysis patients.","authors":"Marios Tsourous, Dimitrios Strepkos, Theodoros Vichos, Michaella Alexandrou, Pedro E P Carvalho, Ahmet Akyel, Parth Desai, Ayman Fath, Sophie Macy, James W Choi, Sevket Gorgulu, Farouc A Jaffer, Raj Chandwaney, Khaldoon Alaswad, Mir B Basir, Lorenzo Azzalini, Dmitrii Khelimskii, Oleg Krestyaninov, Laura Young, Omer Goktekin, Konstantinos Voudris, Noah N Williford, Angie S Lobo, Yader Sandoval, Emmanouil S Brilakis","doi":"10.25270/jic/26.00260","DOIUrl":"https://doi.org/10.25270/jic/26.00260","url":null,"abstract":"<p><strong>Objectives: </strong>To compare characteristics and in-hospital outcomes of dialysis vs non-dialysis patients undergoing chronic total occlusion percutaneous coronary intervention (CTO PCI).</p><p><strong>Methods: </strong>The authors analyzed 18 572 patients undergoing CTO PCI between 2012 and 2026. Outcomes were compared using multivariable logistic regression and propensity score-matching weights. Mortality was evaluated by cumulative center-enrollment category.</p><p><strong>Results: </strong>Overall, 447 patients (2.4%) were receiving dialysis. Compared with non-dialysis patients, they more often had diabetes mellitus (70.5% vs 43.1%), hypertension (93.5% vs 87.1%), heart failure (52.7% vs 27.0%), cerebrovascular disease (17.9% vs 9.1%), peripheral arterial disease (29.1% vs 12.7%), and moderately or severely calcified CTOs (68.2% vs 47.0%; all P < .001). Technical success (85.2% vs 87.4%; P = .190) and procedural success (83.9% vs 86.2%, P = .192) were similar. Retrograde approach (31.1% vs 31.3%; P = .90) and antegrade dissection re-entry (21.3% vs 19.8%; P = .40) were used similarly. In-hospital major adverse cardiac events (MACE) did not differ (2.9% vs 1.9%; P = .11), whereas in-hospital mortality was higher (1.8% vs 0.5%; P = .001) in dialysis patients. The mortality odds ratio (OR) was 2.36 (95% confidence interval [CI], 0.70-5.90; P = .106) in multivariable analysis and 2.42 (95% CI, 1.13-5.16; P = .022) after propensity score weighting. The dialysis-mortality association did not vary across center-enrollment categories (interaction P = .522).</p><p><strong>Conclusions: </strong>Despite greater clinical and angiographic complexity, dialysis patients had no significant differences in procedural success or MACE but had higher in-hospital mortality. The mortality association remained imprecise, and residual confounding cannot be excluded.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicolás Del Cuerpo Salinas, Eduardo Arroyo Úcar, Ignacio Alfaro Paniagua, Marta Monteagudo Viana, María Araceli Frutos García
{"title":"Optical coherence tomography features in coronary vasculitis: a Takayasu arteritis manifestation.","authors":"Nicolás Del Cuerpo Salinas, Eduardo Arroyo Úcar, Ignacio Alfaro Paniagua, Marta Monteagudo Viana, María Araceli Frutos García","doi":"10.25270/jic/26.00091","DOIUrl":"10.25270/jic/26.00091","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miguel Ángel Montilla-Garrido, Santiago Jesús Camacho-Freire, Elena Izaga-Torralba, Carmen Lluch-Requerey, Jessica Roa-Garrido, Oscar Lagos-De Grande, Antonio Enrique Gómez-Menchero
{"title":"Impact of ultra-high-pressure OPN NC balloons in complex coronary interventions: indications, safety, and efficacy.","authors":"Miguel Ángel Montilla-Garrido, Santiago Jesús Camacho-Freire, Elena Izaga-Torralba, Carmen Lluch-Requerey, Jessica Roa-Garrido, Oscar Lagos-De Grande, Antonio Enrique Gómez-Menchero","doi":"10.25270/jic/26.00071","DOIUrl":"10.25270/jic/26.00071","url":null,"abstract":"<p><strong>Objectives: </strong>The OPN super high-pressure noncompliant (NC) balloon (SIS Medical AG) can safely reach inflation pressures of 45 to 50 atm, offering a valuable option for complex coronary interventions. This study aimed to evaluate its safety and efficacy in a real-world setting.</p><p><strong>Methods: </strong>The authors conducted an observational, single-center registry including consecutive patients treated with the OPN balloon over 13 years. Procedural indication, safety, and efficacy were assessed using quantitative coronary angiography (QCA). Major adverse cardiovascular events (MACE)-defined as cardiovascular death, myocardial infarction, or target lesion revascularization-were analyzed at 1-year follow-up.</p><p><strong>Results: </strong>A total of 275 patients (289 lesions) were included. The cohort was highly complex (mean age 70 ± 10 years, 66% multivessel disease, 66% diabetes, 35% in-stent restenosis [ISR]). The main indication was plaque preparation (68%), followed by stent optimization (32%). Procedural success was 95%, with one-third of lesions requiring inflation pressures of greater than or equal to 40 atm. QCA demonstrated a significant increase in minimal lumen diameter (1.31 ± 0.66 mm to 2.13 ± 0.62 mm, P < .001) and a reduction in diameter stenosis (51% to 24%, P < 0.001). Safety outcomes were excellent, with very low complication rates. At 1 year, MACE occurred in 3.8% of patients (stent thrombosis 0.7%). Outcomes were similar between de novo and ISR lesions. Diabetes and chronic kidney disease independently predicted MACE.</p><p><strong>Conclusions: </strong>In routine clinical practice, the OPN NC balloon demonstrated high efficacy and an excellent safety profile, achieving significant luminal gain at ultra-high pressures. These findings support its role for lesion preparation and stent optimization.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148057855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Potential alternative mechanism of hydrodynamic contrast recanalization in complete total occlusion seen on DeepOCT+NIRS imaging.","authors":"Arber Kodra, Danyal Khan, Michael Kim, Tak Kwan","doi":"10.25270/jic/26.00047","DOIUrl":"10.25270/jic/26.00047","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonios Lysandrou, Konstantinos Kalogeras, Maria Ioanna Gounaridi, George E Zakynthinos, Ioannis Gialamas, Nikolaos Vythoulkas-Biotis, Efstratios Katsianos, Chrysovalantis Psathas, Gerasimos Siasos, Emmanouil Vavouranakis
{"title":"Transcatheter treatment of a large saphenous vein graft aneurysm.","authors":"Antonios Lysandrou, Konstantinos Kalogeras, Maria Ioanna Gounaridi, George E Zakynthinos, Ioannis Gialamas, Nikolaos Vythoulkas-Biotis, Efstratios Katsianos, Chrysovalantis Psathas, Gerasimos Siasos, Emmanouil Vavouranakis","doi":"10.25270/jic/26.00075","DOIUrl":"10.25270/jic/26.00075","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147693250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Konstantinos C Theodoropoulos, Matthaios Didagelos, Charalampos Kakderis, George Kassimis, Antonios Ziakas
{"title":"Thrombus migration from the left circumflex to the distal left anterior descending artery during primary percutaneous coronary intervention: an unexpected complication.","authors":"Konstantinos C Theodoropoulos, Matthaios Didagelos, Charalampos Kakderis, George Kassimis, Antonios Ziakas","doi":"10.25270/jic/26.00095","DOIUrl":"10.25270/jic/26.00095","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147693283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hilal Khan, Ayman Al-Atta, Mohamed Farag, Ibrahem Abdalazeem, Fatih Gungoren, Mohammad Alkhalil, Ahmed Abdalwahab, Mia Holley, Scott Wilkes, Bilal Bawamia, Mohaned Egred
{"title":"Safety and outcomes of upfront large-size rotational atherectomy burrs in left main coronary interventions.","authors":"Hilal Khan, Ayman Al-Atta, Mohamed Farag, Ibrahem Abdalazeem, Fatih Gungoren, Mohammad Alkhalil, Ahmed Abdalwahab, Mia Holley, Scott Wilkes, Bilal Bawamia, Mohaned Egred","doi":"10.25270/jic/26.00147","DOIUrl":"10.25270/jic/26.00147","url":null,"abstract":"<p><strong>Objectives: </strong>Data on the safety and efficacy of percutaneous coronary intervention (PCI) with adjunctive rotational atherectomy (RA) in left main (LM) disease are limited. Current guidelines recommend using a small-size RA burr initially, with upsizing if required. The safety of upfront use of a large-size RA burr (≥1.75 mm) is unknown. The authors assessed the safety of an upfront large rotablation burr in the treatment of LM calcification and the procedural and long-term outcome of this approach in comparison to a small-size burr.</p><p><strong>Methods: </strong>Retrospective analysis of all patients undergoing PCI with adjunctive RA to LM disease. The study outcomes were all-cause mortality and repeat target lesion revascularization (TLR) at medium-term follow-up in patients treated with large burr size (≥1.75mm) compared to small burr size (<1.75mm).</p><p><strong>Results: </strong>Two hundred forty-three patients (mean age 75 ± 9 years, 80% males) were included. Approximately half of the patients were treated with a large-size RA burr (≥1.75 mm). Most treated lesions were bifurcation lesions involving the 3 branches (86%) with SYNTAX score of 35 ± 11. Radial access was used in two-thirds of patients; 7F sheath was the most used. There was no difference between the small and large burr groups in procedural complications (11% vs 8%, P = .512), all-cause mortality (34% vs 28%, P = .267), and repeat TLR up to 4 years after PCI (2.9% vs 2.1%, P = .473).</p><p><strong>Conclusions: </strong>Upfront use of a large-size RA burr is feasible and safe for treating calcified LM disease, with no increase in procedural complications, repeat TLR, or medium-term all-cause mortality.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148399722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Breaking barriers: the evolving role of ultra-high pressure balloons for calcified lesions.","authors":"Mehdi Madanchi, Shamir R Mehta","doi":"10.25270/jic/26.00355","DOIUrl":"https://doi.org/10.25270/jic/26.00355","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":"38 10","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149148906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}