Harmanpreet Kaur, Michaella Alexandrou, Ozgur Selim Ser, Deniz Mutlu, Dimitrios Strepkos, Pedro E P Carvalho, Eleni Kladou, Syed Ahmad, Olga Mastrodemos, Bavana V Rangan, Noah Nick Williford, Silvia Moscardelli, Lorenzo Azzalini, M Nicholas Burke, Yader Sandoval, Emmanouil S Brilakis
{"title":"Emergency cardiac surgery after percutaneous coronary intervention: insights from the PROGRESS-Complications Registry.","authors":"Harmanpreet Kaur, Michaella Alexandrou, Ozgur Selim Ser, Deniz Mutlu, Dimitrios Strepkos, Pedro E P Carvalho, Eleni Kladou, Syed Ahmad, Olga Mastrodemos, Bavana V Rangan, Noah Nick Williford, Silvia Moscardelli, Lorenzo Azzalini, M Nicholas Burke, Yader Sandoval, Emmanouil S Brilakis","doi":"10.25270/jic/25.00383","DOIUrl":"https://doi.org/10.25270/jic/25.00383","url":null,"abstract":"<p><strong>Objectives: </strong>Emergency surgery is an infrequent but severe complication of percutaneous coronary intervention (PCI). The authors sought to examine clinical characteristics, procedural features, and outcomes of patients undergoing emergency cardiac surgery after PCI.</p><p><strong>Methods: </strong>The authors analyzed the clinical characteristics and outcomes of 15 patients who underwent emergency surgery after PCI from the PROGRESS-COMPLICATIONS registry.</p><p><strong>Results: </strong>Of 18 691 patients who underwent PCI at 2 tertiary care centers between 2016 and 2023, 15 (0.08%) required emergency surgery: 14 underwent coronary artery bypass graft surgery (CABG) and 1 underwent aortic valve replacement and CABG. Patients had high prevalence of comorbidities such as hypertension (93.3%), diabetes mellitus (73.3%), dyslipidemia (93.3%), and prior heart failure (53.3%). The most common presentations included non-ST segment elevation acute myocardial infarction (40.0%) and stable angina (33.3%). Target lesions were complex and often had moderate/severe calcification (60.0%) or involved a bifurcation (40.0%). Mechanical circulatory support was used in 53.3% (intra-aortic balloon pump 12.5%; Impella 2.5 [Abiomed] 12.5%; Impella 5.0 37.5%; Impella CP 12.5%; venoarterial extracorporeal membrane oxygenation 25.0%). In-hospital mortality was 33.3%. The most common indications for emergent CABG were coronary dissection (46.7%), aortocoronary dissection (26.7%), and coronary perforation (26.7%). Post-CABG complications included death (33.3%), arrhythmia (33.3%), hemodynamic instability (26.7%), and cardiogenic shock (13.3%). The median hospital stay was 10.0 days (6.0-18.5). During a median follow-up of 24 months, 53.3% of patients experienced major adverse cardiovascular events (MACE), 46.7% died, and 26.7% required target vessel revascularization.</p><p><strong>Conclusions: </strong>Patients who underwent emergency surgery after PCI had multiple comorbidities, complex coronary anatomy, and high incidence of MACE.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Potential alternative mechanism of hydrodynamic contrast recanalization in complete total occlusion seen on DeepOCT+NIRS imaging.","authors":"Arber Kodra, Danyal Khan, Michael Kim, Tak Kwan","doi":"10.25270/jic/26.00047","DOIUrl":"https://doi.org/10.25270/jic/26.00047","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dimitrios Strepkos, Michaella Alexandrou, Pedro E P Carvalho, Eleni Kladou, Nick Williford, Olga Mastrodemos, Bavana V Rangan, Yader Sandoval, Emmanouil S Brilakis
{"title":"Quantification of myocardial mass using coronary computed tomography angiography in bifurcation PCI and association with outcomes.","authors":"Dimitrios Strepkos, Michaella Alexandrou, Pedro E P Carvalho, Eleni Kladou, Nick Williford, Olga Mastrodemos, Bavana V Rangan, Yader Sandoval, Emmanouil S Brilakis","doi":"10.25270/jic/25.00382","DOIUrl":"https://doi.org/10.25270/jic/25.00382","url":null,"abstract":"<p><strong>Objectives: </strong>To determine if quantification of the myocardial mass supplied by a side branch (SB) could be predictive of bifurcation percutaneous coronary intervention (PCI) outcomes.</p><p><strong>Methods: </strong>The authors examined the characteristics and outcomes of 73 patients (81 lesions) who underwent bifurcation PCI and had coronary computed tomography angiography (CCTA) angiography based computed flow-based calculation of myocardial mass at risk within 6 months prior.</p><p><strong>Results: </strong>The lesions analyzed were complex with high V-RESOLVE scores (12.0, 95%, interquartile range [IQR]: 9.0, 13.5). Provisional stenting was used in 67.9%, 2-stent techniques in 32.1%, and conversion from provisional to 2-stent stenting was performed in 11.1% of the lesions. The main vessel (MV) supplied 30.0% (IQR: 24.0%, 36.0%) and the SB supplied 10.0% (IQR: 7.0%, 13.0%) of the myocardium. Technical success was 94.9%. Major adverse cardiovascular events (MACE) occurred in 5.5% of the patients and SB occlusion (SBO) in 12.3% of the lesions. The ratio of SB to MV myocardial mass supply (SB/MV) was not associated with technical success (odds ratio [OR], 11.00; 95% confidence interval [CI], 0.01, 18.79; P = .500) or MACE (OR, 0.02; 95% CI, 0.00, 18.20; P = .300), but was associated with SBO (OR, 6.02*10-6; 95% CI, 2.42*10-10, 0.15; P = .020). SB/MV was normally distributed (W = 0.99, P = .467) with a mean of 0.35 (95% CI, 0.31, 0.38). In lesions where SBO occurred, V-RESOLVE scores were higher (16.0 vs 12.0, P = .017) and the SB/MV ratio was lower (0.22 vs 0.35, P = .007).</p><p><strong>Conclusions: </strong>Myocardial mass derived from CT analysis can help assess the risk of SBO after bifurcation PCI.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Haisum Maqsood, Robert S Zhang, Sripal Bangalore
{"title":"Drug-eluting stent, drug-coated balloon, or conventional angioplasty for in-stent coronary restenosis: an updated meta-analysis of randomized trials.","authors":"M Haisum Maqsood, Robert S Zhang, Sripal Bangalore","doi":"10.25270/jic/26.00028","DOIUrl":"https://doi.org/10.25270/jic/26.00028","url":null,"abstract":"<p><strong>Objectives: </strong>The SELUTION SLR 014 In-stent Restenosis (SELUTION4ISR) trial showed noninferiority of DCB for the outcome of target lesion failure (TLF) when compared with standard of care (80% DES and 20% POBA). It was notable that in the DCB vs DES subgroup analysis there was a numerically higher rate of TLF with DCB (15.3% vs 7.1%). The authors aimed to re-evaluate the outcomes of drug-eluting stent (DES), drug-coated balloon (DCB), or plain old balloon angioplasty (POBA) in patients with coronary in-stent restenosis (ISR).</p><p><strong>Methods: </strong>The authors searched PubMed and EMBASE databases for randomized clinical trials (RCTs) that compared these 3 percutaneous revascularization strategies for ISR until March 15, 2026. Outcomes included major adverse cardiovascular events (MACE), target lesion revascularization, all-cause mortality, cardiovascular mortality, and stent thrombosis.</p><p><strong>Results: </strong>From 19 RCTs that randomized 4238 patients with ISR at mean follow-up of 19.6 months, there was a significant reduction in MACE and TLR with both DCB (OR, 0.35; 95% CI, 0.24-0.52 and OR, 0.28; 95% CI, 0.16-0.49, respectively) and DES (OR, 0.35; 95% CI, 0.24-0.52 and OR, 0.22; 95% CI, 0.12-0.42, respectively) when compared with POBA. There were no significant differences in clinical outcomes between DCB and DES.</p><p><strong>Conclusions: </strong>In patients with ISR, DCB reduced MACE/TLR when compared with POBA. There were no clinical differences between DCB and DES even after inclusion of the SELUTION4ISR trial, thus suggesting that DCB are reasonable alternative to repeat stenting in patients presenting with ISR.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew Atienza, Ahmad Alkhalil, Neda Dianati Maleki, Jonathan Price, Daniel Montellese, Puja Parikh
{"title":"Closure of symptomatic mitral paravalvular leak following recent transcatheter mitral valve-in-ring.","authors":"Matthew Atienza, Ahmad Alkhalil, Neda Dianati Maleki, Jonathan Price, Daniel Montellese, Puja Parikh","doi":"10.25270/jic/26.00050","DOIUrl":"https://doi.org/10.25270/jic/26.00050","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147693280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Argisjt Mkrtchjan, Eleni Ntantou, Alexandros A Siskos, Jacob J Elscot, Jeroen M Wilschut, Rutger-Jan Nuis, Roberto Diletti, Joost Daemen, Isabella Kardys, Nicolas M Van Mieghem, Wijnand K den Dekker
{"title":"The impact of clinical presentation on one-year major adverse cardiac events in patients with angiographically defined moderate to severe calcified coronary artery disease.","authors":"Argisjt Mkrtchjan, Eleni Ntantou, Alexandros A Siskos, Jacob J Elscot, Jeroen M Wilschut, Rutger-Jan Nuis, Roberto Diletti, Joost Daemen, Isabella Kardys, Nicolas M Van Mieghem, Wijnand K den Dekker","doi":"10.25270/jic/26.00022","DOIUrl":"https://doi.org/10.25270/jic/26.00022","url":null,"abstract":"<p><strong>Objectives: </strong>The authors aimed to investigate the impact of clinical presentation on 1-year major adverse cardiac events (MACE) in patients with angiographically defined moderate or severe calcified coronary artery disease.</p><p><strong>Methods: </strong>The authors conducted a retrospective, single-center cohort study in patients with moderate to severe coronary calcification who underwent percutaneous coronary intervention (PCI) between June 2020 and July 2021 with either chronic coronary syndrome (CCS) or acute coronary syndrome (ACS). The primary endpoint was 1-year MACE, a composite of all-cause mortality, myocardial infarction (MI), and ischemia-driven revascularization. Cox proportional hazards regression was used.</p><p><strong>Results: </strong>Seven hundred twenty-four patients were included: 420 patients with ACS and 304 patients with CCS. The median age was 72.0 years. There were relatively more men in the CCS cohort (76.0% vs 66.2%, P = .005). Procedure time was longer in the context of CCS (88 minutes [25th-75th percentile: 56-104] vs 78 minutes [66-121], P < .001). Application of atherectomy and lithotripsy was similar in both cohorts. No significant difference was observed in the cumulative incidence of MACE between the ACS (15.0%) and CCS (16.4%) groups (HR, 0.94; 95% CI, 0.65-1.36; P = .74). Secondary outcomes, such as all-cause mortality, MI, and ischemia-driven revascularization, did not result in statistical significance between the groups.</p><p><strong>Conclusions: </strong>The cumulative incidence of 1-year MACE and its composites did not show statistically significant difference between patients with moderate or severe calcification in the context of CCS or ACS. This suggests that the clinical presentation of patients with calcified coronary arteries does not significantly affect their outcomes.</p>","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147693261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonios Lysandrou, Konstantinos Kalogeras, Maria Ioanna Gounaridi, George E Zakynthinos, Ioannis Gialamas, Nikolaos Vythoulkas-Biotis, Efstratios Katsianos, Chrysovalantis Psathas, Gerasimos Siasos, Emmanouil Vavouranakis
{"title":"Transcatheter treatment of a large saphenous vein graft aneurysm.","authors":"Antonios Lysandrou, Konstantinos Kalogeras, Maria Ioanna Gounaridi, George E Zakynthinos, Ioannis Gialamas, Nikolaos Vythoulkas-Biotis, Efstratios Katsianos, Chrysovalantis Psathas, Gerasimos Siasos, Emmanouil Vavouranakis","doi":"10.25270/jic/26.00075","DOIUrl":"https://doi.org/10.25270/jic/26.00075","url":null,"abstract":"","PeriodicalId":49261,"journal":{"name":"Journal of Invasive Cardiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147693250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}