BMC Surgery最新文献

{"title":"Prospective evaluation of surgical treatment of liver metastasizing pancreatic cancer - ScanPan study protocol.","authors":"Kristina Hasselgren, Caroline Williamsson, Johanna Wennerblom, Poya Ghorbani, Maria Gustafsson Liljefors, Heikki Huhta, Margareta Heby, Christopher Månsson, Mia I Johansson, Nils O Elander, Minna Nortunen, Raija Kallio, Asif Halimi, Daniel Öhlund, Per Sandström, Ernesto Sparrelid, Bergthor Björnsson","doi":"10.1186/s12893-025-02983-w","DOIUrl":"10.1186/s12893-025-02983-w","url":null,"abstract":"<p><strong>Introduction: </strong>Patients with pancreatic ductal adenocarcinoma (PDAC) have a dismal prognosis. The majority of patients are diagnosed at an advanced stage, and for these patients, the only possible treatment is palliative chemotherapy. There are increasing data from retrospective studies indicating that a subgroup of patients with liver-limited metastases may benefit from surgical treatment of liver metastases. However, there is a need for prospective trials.</p><p><strong>Objective: </strong>The aim of this study is to prospectively investigate the safety and feasibility of surgically treating patients who are resectable, including those with borderline venous resectable, histopathologically confirmed PDAC, and histopathologically or radiologically confirmed liver metastases.</p><p><strong>Methods: </strong>Five Swedish and one Finnish hepatopancreaticobiliary (HPB) centre will participate. Eligible patients will be identified at regional multidisciplinary conferences (MDTs). Before inclusion, they will undergo computed tomography (CT), magnetic resonance imaging (MRI, ) and (positron emission tomography computed tomography)PET-CT to rule out extrahepatic metastases. To be included, patients will have to have four or fewer liver metastases, which must be no larger than 5 cm for patients planning for resection and no larger than 2 cm for patients planning for ablation. The metastases may be either synchronous or metachronous. Patients will undergo four months of chemotherapy before surgical treatment (either resection or ablation), and postoperatively, they will undergo two months of chemotherapy. For those with synchronous metastases, resection of the pancreatic tumour will be performed. Follow-up will be performed over two years postoperatively with regular CT scans and assessments of quality of life.</p><p><strong>Conclusions: </strong>In conclusion, this trial will provide increased knowledge concerning whether surgical treatment of liver metastases from pancreatic cancer can result in improved survival.</p><p><strong>Clinical trial number: </strong>Clinical.</p><p><strong>Trials: </strong>gov (NCT05271110), registered February 26^th 2022.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"299"},"PeriodicalIF":1.6,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12275338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Favorable outcomes with jejunal interposition without vascular anastomosis for esophagectomy in cancer patients: a single-center experience.","authors":"Lilan Zhao, Yun Ding, Juan Zhang, Pengjie Tu, Zijie He, Genglin Li, Zhaoxian Lin, Xing Lin, Zhiwei Lin, Zhenlong Zhang, Tianxing Guo, Lihuan Zhu, Wenshu Chen, Debin Ou, Xiaojie Pan","doi":"10.1186/s12893-025-03006-4","DOIUrl":"10.1186/s12893-025-03006-4","url":null,"abstract":"<p><strong>Background: </strong>The standard esophageal replacement for esophageal cancer treatment is a gastric conduit. However, jejunal interposition is often utilized when the stomach is not available. The purpose of this study was to review our experience with this technique, particularly in cases not requiring microvascular anastomosis, and assess surgical outcomes.</p><p><strong>Methods: </strong>We retrospectively reviewed the medical records of cancer patients who underwent jejunum interposition at our institution from 2003 to 2020. Data regarding patient characteristics, operative technique, and postoperative outcomes were collected and analyzed. Factors affecting oncologic outcomes were evaluated using Kaplan-Meier estimates and Cox regression. Postoperative conduit function was assessed at 6 months.</p><p><strong>Results: </strong>With a median follow-up of 35 months, 122 patients (113 males and 9 females; aged 40 to 86 years) were included. Over half (54.9%, 67/122) had stage III or higher disease. Median operation time was 270 min, and the median drainage time was 8 days. Postoperative complications occurred in 28.7% of patients, with pulmonary infections being the most common. The anastomotic leakage rate was 4.1% (5/122), and the 90-day mortality rate was 5.7%. The overall survival rates at 1, 3, and 5 years were 79.5%, 49.0%, and 35.6%, respectively. The prognosis was mainly correlated with tumor stage and most patients reported good quality of life.</p><p><strong>Conclusion: </strong>Our findings suggests that, even without vascular anastomosis, jejunal conduit is a feasible procedure for reconstruction after esophagectomy, resulting in low morbidity and favorable prognosis.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"302"},"PeriodicalIF":1.6,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12275394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for different cement distribution indexes for refracture of operated vertebrae and adjacent vertebrae after percutaneous vertebroplasty in patients with thoracolumbar compression fracture.","authors":"Sulaiman Reheman, Wuluhan Mahan, Aerpati Maimaiti, Liu Yuntao, Aiben Kayierhan, Ma Liang, Alimujinag Aximu, Tuerhongjiang Abudurexiti, Meng Xiangyu","doi":"10.1186/s12893-025-03033-1","DOIUrl":"10.1186/s12893-025-03033-1","url":null,"abstract":"<p><strong>Background: </strong>Although most studies suggest that unilateral percutaneous vertebroplasty (PVP) increases the probability of secondary adjacent vertebral compression fractures, controversy remains the associated risk factors.</p><p><strong>Objective: </strong>To explore the risk factors of bone cement distribution index (DI) for surgical and adjacent vertebrae after PVP.</p><p><strong>Methods: </strong>According to the inclusion criteria, 329 patients who underwent PVP in the Spinal Surgery Department of the Sixth Affiliated Hospital of Xinjiang Medical University between January 2018 and May 2024 were then retrospectively screened, and the patients were divided into two groups based on whether refracture occurred during the follow-up period. The two groups were (1) fracture group (n = 47) and (2) no fracture group (n = 282). The following variables were reviewed in both groups: age, gender, body mass index (BMI), PVP segment, cement leakage, bone density, T, cement dose, smoking, drinking, hypertension, type 2 diabetes mellitus, COPD, cerebral hemorrhage, coronary heart disease, cement DI type, chronic kidney history and previous fracture (caused by osteoporosis). These factors were univariate analyzed and replaced P < 0.05 with binary Logistic analysis to explore the factors associated with postoperative vertebral recompression fracture.</p><p><strong>Results: </strong>A total of 329 patients were included in this study to compare the parameters between the fracture and nonfracture groups. The results of univariate analysis showed that postoperative vertebral refracture was related to age, cement leakage, bone mineral density T value, history of hypertension, history of type 2 diabetes mellitus, the index type of bone cement distribution, and chronic kidney disease, and the difference was statistically significant (P < 0.05). By binary Logistic regression, Age (OR = 1.103, 95%CI:1.041-1.179, P = 0.002), leakage of bone cement (OR = 11.790,95%CI:4.942-30.637,P < 0.001) MD T value (OR = 5.716, 95%CI: 1.575-28.548, P = 0.016), history of hypertension (OR = 2.721, 95%CI:1.155-6.612, P = 0.023), history of chronic kidney disease (OR = 6.360, 95%CI:1.435-30.833, P = 0.017), type I bone cement DI [OR = 13.636, 95%CI: 3.126-98.477, P = 0.002] and type II cement DI [OR = 8.590, 95%CI:1.890-62.651, P = 0.012] was a risk factor for refracture of the operated and adjacent vertebrae.</p><p><strong>Conclusion: </strong>The results showed that age, cement leakage, bone mineral density T value, history of hypertension, and cement DI type were risk factors for refracture of the operated vertebrae and adjacent vertebrae. The surgeon conducts a comprehensive evaluation of patients before surgery, which can more accurately estimate the probability of fracture again, and then provide a reference for the formulation of personalized treatment plan, so as to reduce the risk of fracture again in the future.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"306"},"PeriodicalIF":1.6,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12275346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of complications associated with prolonged post-operative hospitalization and postoperative outcomes in elderly patients with high BMI undergoing elective total knee arthroplasty.","authors":"Fangxing Wang, Jie Zhao, Weijie He, Huazheng He, Qiang Wang","doi":"10.1186/s12893-025-03050-0","DOIUrl":"10.1186/s12893-025-03050-0","url":null,"abstract":"","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"303"},"PeriodicalIF":1.6,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12275447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender-based differences of intraoperative transfusion during open surgery for descending thoracic and abdominal aortic aneurysms: a retrospective single-center cohort study.","authors":"Jianfeng Gao, Ruxuan Wang, Fangda Li, Rong Zeng, Yuexin Chen, Yuehong Zheng","doi":"10.1186/s12893-025-03020-6","DOIUrl":"10.1186/s12893-025-03020-6","url":null,"abstract":"<p><strong>Background: </strong>Several studies have reported gender-based differences in prognosis following open surgery repair (OSR) and endovascular therapy for treating aortic aneurysms. However, the blood transfusion rates for both gender and the predictors of intraoperative transfusion during OSR for Descending Thoracic and Abdominal Aortic Aneurysms (DTAA) remain uncertain.</p><p><strong>Methods: </strong>Data of Patients with DTAA who underwent OSR at our center between August 2002 and December 2021 were retrospectively collected. Specific aneurysms and preoperative anemia were excluded from the study. Transfusion of blood products was recorded. Logistic regression analyses were conducted to identify the factors significantly related to transfusion. An adjusted analysis of the association between gender and red blood cell (RBC) transfusion was performed.</p><p><strong>Results: </strong>A total of 82 patients were included, of whom 23 were female. Forty-six DTAAs received intraoperative RBC transfusions. The transfusion rates for male and female were 45.8% and 82.6%, respectively. Preoperative hemoglobin concentration (Hb) was similar between the transfusion and no-transfusion cohorts. Female gender, thoracoabdominal aortic aneurysm, increased procedure duration, blood loss, and urine volume were associated with higher intraoperative transfusion rates. Female gender was identified as an independent predictor (odds ratio [OR], 5.24; P = 0.034). Preoperative Hb, statin use, blood loss, and urine volume were significantly different between gender. After adjusting for these four factors, an association between female gender and RBC transfusion was also found (OR, 6.63; P = 0.037). According to the receiver operator characteristic curve (ROC), increased age (cutoff = 66 years, area under curve [AUC] = 0.81, P = 0.044) and longer procedure duration (cutoff = 245 min, AUC = 0.84, P = 0.021) were found to have significant predictive value for intraoperative transfusion in women.</p><p><strong>Conclusion: </strong>Women with DTAA may have a higher requirement for intraoperative RBC transfusion. Therefore, women appear to require more comprehensive RBC preparation plans for elective OSR.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"305"},"PeriodicalIF":1.6,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12275295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of reproductive outcomes after laparoscopic tubal anastomosis using conventional (non-barbed) sutures and barbed sutures.","authors":"Ceyda Karadag, Burak Karadag","doi":"10.1186/s12893-025-03043-z","DOIUrl":"10.1186/s12893-025-03043-z","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to compare reproductive outcomes after laparoscopic tubal anastomosis using conventional (non-barbed) and barbed sutures.</p><p><strong>Methods: </strong>This retrospective cohort study was conducted at a single center between January 2016 and December 2021. Thirty-nine women undergoing laparoscopic tubal anastomosis were divided into two groups: a non-barbed suture (5 - 0 polyglactin suture) group (16 women), and a barbed suture (5 - 0 unidirectional barbed suture) group (23 women). Demographic data, operation times, reversal operation success rates, pregnancy rates, and other factors were compared between the two groups.</p><p><strong>Results: </strong>The mean operation time was significantly shorter in the barbed suture group (55.8 ± 7.33 min) than in the non-barbed suture group (108.7 ± 17.27 min) (p = 0.001). The overall pregnancy rate was significantly higher in the barbed suture group (87%) than in the non-barbed suture group (56.3%) (p = 0.037). The rate of intrauterine pregnancy was also significantly higher in the barbed suture group (p = 0.041). The intervals between surgery and pregnancy did not differ significantly between the two groups.</p><p><strong>Conclusion: </strong>The use of barbed sutures in laparoscopic tubal anastomosis can result in shorter operation times and better reproductive outcomes than the use of conventional sutures.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"301"},"PeriodicalIF":1.6,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12275361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of 30-day mortality in major lower limb amputations: insights from a five-year retrospective study in a South Asian LMIC.","authors":"Mohammad Zakriya, Zia Ur Rehman, Muhammad Anees, Hafsa Shaikh, Adnan Qadir Memon, Nadeem Ahmed Siddiqui, Fareed Shaikh","doi":"10.1186/s12893-025-03013-5","DOIUrl":"10.1186/s12893-025-03013-5","url":null,"abstract":"<p><strong>Background: </strong>Major lower limb amputation (MLLA) is a life-saving procedure with significant morbidity and mortality. The objectives of this study were to determine the incidence of 30-day mortality, perioperative complications, and predictive risk factors of mortality in MLLA patients.</p><p><strong>Methods: </strong>This retrospective cohort study included patients undergoing MLLA at The Aga Khan University Hospital, Pakistan, from January 2018 to December 2022. Data was collected using chart reviews and analyzed via Stata 15. Demographic, clinical, and procedural variables were examined. Predictive factors for 30-day mortality were assessed using Firth logistic regression.</p><p><strong>Results: </strong>Among 286 patients, the mean age was 49.4 ± 20.9 years, and 79.4% were male. The leading indications for MLLA were diabetic foot (43.4%) and trauma (23.8%). Thirty-day mortality was 6.6%. Most deaths occurred in patients with diabetic foot (68.4%), chronic kidney disease (31.6%), or ischemic heart disease (36.8%). Below-knee amputation accounted for 68.4% of cases. Postoperative infections (11.2%) and stump necrosis (4.2%) were the most common complications. Multivariable analysis identified chronic kidney disease (OR: 3.613; 95% CI: 1.112-11.739; p = 0.033) and postoperative local wound infection (OR: 3.416; 95% CI: 1.036-11.267; p = 0.044) as significant predictors of 30-day mortality in this cohort.</p><p><strong>Conclusion: </strong>MLLA is associated with considerable short-term mortality, particularly among patients with chronic kidney disease and postoperative surgical site infections. These findings emphasize the need for proactive identification of high-risk individuals, optimization of comorbid conditions, especially renal function, and strengthening perioperative infection control practices to improve patient outcomes in resource-limited settings.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"300"},"PeriodicalIF":1.6,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12275337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the effects of laparoscopic sleeve gastrectomy and endoscopic intragastric balloon placement on hormone profile and menstrual cycle in obese women with polycystic ovary syndrome.","authors":"Omer Tammo, Esra Söylemez, Hüseyin Bayhan","doi":"10.1186/s12893-025-03039-9","DOIUrl":"10.1186/s12893-025-03039-9","url":null,"abstract":"<p><strong>Background and aim: </strong>Obesity is a significant public health problem with increasing prevalence worldwide, and polycystic ovary syndrome (PCOS) is a common comorbidity in obese women. PCOS is characterized by hormonal imbalances, menstrual irregularities, infertility, and metabolic disorders. Weight management is critical in obese women with PCOS to improve both reproductive health and achieve metabolic and hormonal balance. To this end, surgical treatments have come to the forefront, and procedures such as laparoscopic sleeve gastrectomy (LSG) and endoscopic intragastric balloon (EIB) placement are being used increasingly.</p><p><strong>Methods and results: </strong>This is a retrospective study conducted at [Blinded for review] between January 2022 and October 2024. It compares the effects of laparoscopic sleeve gastrectomy and endoscopic intragastric balloon placement in female patients aged 18-40 who were diagnosed with PCOS and obesity. In the study, anthropometric measurements, hormonal parameters, and menstrual cycles were evaluated before treatment and 6 months after treatment and analyzed between the two groups. There was no difference in age between patients who underwent laparoscopic sleeve gastrectomy and endoscopic intragastric balloon placement (p = 0.424). The preoperative BMI and the difference between preoperative and postoperative BMI were higher in the LSG group (p < 0.001), but the postoperative BMI values were similar between the two groups (p = 0.583). The waist/hip ratio was higher in the LSG group (p < 0.001, p = 0.010, p < 0.001). While both surgeries showed a reduction in free androgen index and AMH, this reduction was not statistically significant (p > 0.05), both surgeries increased SHBG (p > 0.05). The decrease in AMH was greater in the LSG group (p = 0.020). Total testosterone decreased in the sleeve gastrectomy group (p < 0.001) and the menstrual cycle improved (p = 0.035).</p><p><strong>Conclusion: </strong>In summary, both laparoscopic sleeve gastrectomy and endoscopic intragastric balloon placement led to positive changes in hormone profiles and menstrual cycle characteristics. However, LSG was found to be more effective on these parameters.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"297"},"PeriodicalIF":1.6,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12269097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of laparoscopic and open total gastrectomy with D2 lymphadenectomy for gastric cancer: a propensity score matched study.","authors":"Deniz Kütük, Mehmet Ali Koç, Atıl Çakmak, Akın Fırat Kocaay","doi":"10.1186/s12893-025-03044-y","DOIUrl":"10.1186/s12893-025-03044-y","url":null,"abstract":"<p><strong>Background: </strong>Laparoscopic total gastrectomy (LTG) is increasingly performed for gastric cancer, yet concerns remain regarding its oncologic adequacy compared to open total gastrectomy (OTG), especially outside of randomized clinical trials. Real-world data comparing both techniques are still limited.</p><p><strong>Methods: </strong>This retrospective cohort study included patients who underwent total gastrectomy with D2 lymphadenectomy for gastric cancer between January 2016 and December 2021 at a single tertiary center. Patients were grouped as LTG or OTG. Propensity score matching (1:1) was used to adjust for baseline variables. Long-term clinical outcomes and survival data were compared. Complications were graded using the Clavien-Dindo classification. Kaplan-Meier analysis was used to evaluate disease-free survival (DFS) and overall survival (OS).</p><p><strong>Results: </strong>After propensity score matching (24 LTG vs. 24 OTG), the LTG group demonstrated a significantly shorter hospital stay (6.79 ± 0.66 vs. 7.33 ± 0.64 days; p = 0.006), with comparable operative times (3.5 ± 0.42 vs. 3.5 ± 0.49 h; p = 1.000) and complication rates (16.7% vs. 20.8%; p = 0.71), all classified as Clavien-Dindo Grade I-II. Oncologic outcomes showed equivalent lymph node yield. Oncologic outcomes were equivalent, including lymph node yield (35.12 ± 9.32 vs. 36.46 ± 10.19; p = 0.639). Survival analysis revealed no significant differences: median overall survival was 6 years (95% CI: 3.87-8.12) for LTG vs. 4 years (2.16-5.83) for OTG (p = 0.541), and disease-free survival was 6 years (4.53-7.46) vs. 4 years (1.72-6.27) (p = 0.443), with a median follow-up of 28.4 months.</p><p><strong>Conclusion: </strong>Laparoscopic total gastrectomy is a safe and effective alternative to open surgery when performed by experienced surgeons. These findings support the feasibility of LTG in real-life clinical settings and complement existing evidence from randomized trials.</p><p><strong>Trial registration: </strong>retrospectively registered.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"298"},"PeriodicalIF":1.6,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12269198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy analysis of robot-assisted minimally invasive surgery for the treatment of unstable pelvic fractures.","authors":"Dai Yonghong, Zeng Yanhui, Hong Shi, Zhou Jiansheng, Zhao Chunpeng","doi":"10.1186/s12893-025-03065-7","DOIUrl":"10.1186/s12893-025-03065-7","url":null,"abstract":"","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"296"},"PeriodicalIF":1.6,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12269219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}