BMC Surgery最新文献

{"title":"Body mass index and post-thyroidectomy hypocalcemia: a protective effect of overweight through non-surgical mechanisms-a propensity score-matched study.","authors":"Junhao Li, Yuanxiao Yin, Luyuan Lu, Haiqiang Pan, Xv Luo, Shichen Meng, Yixiong Zheng","doi":"10.1186/s12893-025-02850-8","DOIUrl":"https://doi.org/10.1186/s12893-025-02850-8","url":null,"abstract":"<p><strong>Background: </strong>Postoperative hypocalcemia is a common complication after total thyroidectomy (TT). Recent studies suggest that body mass index (BMI) may influence its occurrence. This study aimed to investigate whether overweight reduces postoperative hypocalcemia after TT and to investigate the impact of surgical and non-surgical factors on postoperative hypocalcemia in patients undergoing total thyroidectomy.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 228 patients who underwent TT for papillary thyroid carcinoma between January 2021 and January 2024. Patients were categorized into overweight (BMI ≥ 25 kg/m², n = 96) and non-overweight groups (BMI < 25 kg/m², n = 132). Propensity score matching (PSM) was performed to balance confounding factors. Postoperative hypocalcemia, hypoparathyroidism rates, and related biochemical markers were compared between matched groups.</p><p><strong>Results: </strong>After PSM (51 pairs), baseline characteristics were balanced except for Total Cholesterol (TC) (1.40 ± 0.83 vs 1.99 ± 1.80 mmol/L, P = 0.036), High-density lipoprotein cholesterol (HDL-C) (1.30 ± 0.34 vs 1.10 ± 0.23 mmol/L, P < 0.001), and fatty liver presence (35.5% vs 75.0%, P = 0.001). Postoperative hypocalcemia was significantly higher in the non-overweight group (78.4% vs 54.9%, P = 0.020), while hypoparathyroidism rates showed no significant difference (54.9% vs 62.7%, P = 0.546). Postoperative calcium levels were higher in the overweight group (2.11 ± 0.12 vs 2.05 ± 0.12 mmol/L, P = 0.014).</p><p><strong>Conclusions: </strong>Non-overweight patients are more likely to develop hypocalcemia after TT compared to overweight patients. The protective effect of overweight appears to operate through non-surgical mechanisms, as evidenced by similar hypoparathyroidism rates between groups. Further research is needed to elucidate the specific mechanisms involved.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"146"},"PeriodicalIF":1.6,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radical cystectomy for bladder cancer in Sub-Saharan Africa: techniques, challenges, and survival outcomes: a comprehensive review.","authors":"Charles John Nhungo, Obadia Venance Nyongole, Charles Anaeli Mkony","doi":"10.1186/s12893-025-02887-9","DOIUrl":"https://doi.org/10.1186/s12893-025-02887-9","url":null,"abstract":"<p><p>Radical cystectomy (RC) with urinary diversion remains the gold-standard treatment for muscle-invasive bladder cancer (MIBC), yet its implementation in Sub-Saharan Africa is hindered by late-stage presentation, limited surgical expertise, and inadequate perioperative care. These challenges contribute to higher morbidity and poorer survival outcomes compared to high-income regions. Additionally, the high prevalence of schistosomiasis-associated squamous cell carcinoma, disparities in multidisciplinary cancer care, and the burden of comorbidities further complicate treatment.This review examines RC techniques practiced in Africa, from open to minimally invasive approaches, assessing their feasibility within resource-limited settings. It explores challenges specific to the region, highlighting the impact of infrastructure gaps, limited access to neoadjuvant and adjuvant therapies, and variations in surgical training. Addressing these barriers requires urgent investment in oncology infrastructure, expanded access to multimodal therapy, and early detection strategies. Optimizing perioperative management and promoting cost-effective urinary diversion techniques are critical to improving bladder cancer outcomes in the region.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"143"},"PeriodicalIF":1.6,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Confounding effects of blood hemoglobin and hematocrit levels on flap perfusion measurement with the Oxygen-to-see (O2C) analysis system in microvascular head and neck reconstruction- a retrospective study.","authors":"Mark Ooms, Philipp Winnand, Marius Heitzer, Anna Bock, Marie Katz, Johannes Bickenbach, Frank Hölzle, Ali Modabber","doi":"10.1186/s12893-025-02888-8","DOIUrl":"https://doi.org/10.1186/s12893-025-02888-8","url":null,"abstract":"<p><strong>Background: </strong>The Oxygen-2-see (O2C) analysis system can measure flap perfusion, which is a prerequisite for flap viability, and it is therefore commonly used in flap monitoring for microvascular head and neck reconstruction. However, in the context of predefined threshold values for perfusion parameters indicating vascular flap compromise, it is unclear whether blood hemoglobin and hematocrit levels are confounding variables. The aim of this study was to investigate the influence of blood hemoglobin and hematocrit levels on flap perfusion parameters.</p><p><strong>Methods: </strong>Perfusion parameters (i.e., flap blood flow, hemoglobin concentration, and hemoglobin oxygen saturation) measured intraoperatively and postoperatively with the O2C analysis system at 8- and 2-mm tissue depths were retrospectively analyzed in 125 patients reconstructed with a radial free forearm flap (RFFF), an anterolateral thigh flap (ALTF), or a fibula free flap (FFF) between 2011 and 2020. Associations between perfusion parameters and blood hemoglobin and hematocrit levels were analyzed using Spearman correlation coefficient and multiple linear regression models.</p><p><strong>Results: </strong>Postoperative hemoglobin concentration at a 2-mm tissue depth was associated with blood hemoglobin and hematocrit levels in RFFFs (r = 0.259, p = 0.031; and r = 0.268, p = 0.026; respectively). Both associations persisted in multivariable regression analysis (p = 0.040 and p = 0.036). No other associations between perfusion parameters and blood hemoglobin and hematocrit levels were observed for RFFFs, ALTFs or FFFs (all p > 0.05).</p><p><strong>Conclusions: </strong>For the perfusion parameters flap blood flow and hemoglobin oxygen saturation no association with blood hemoglobin or hematocrit levels was observed. This underlines the validity of absolute threshold levels for indicating vascular flap compromise in the context of flap monitoring with the O2C analysis system.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"145"},"PeriodicalIF":1.6,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of esketamine intravenous analgesic pump on pain and depression post-cesarean.","authors":"Xiao-Qiang Zhang, Shuang Li, Xiao-Lin Qin","doi":"10.1186/s12893-025-02868-y","DOIUrl":"https://doi.org/10.1186/s12893-025-02868-y","url":null,"abstract":"<p><strong>Background: </strong>Postoperative pain and psychological well-being in postpartum women following cesarean section are critical for optimal maternal recovery. Traditional analgesics often have limitations and side effects, prompting the need for alternative solutions. This study evaluates the impact of an esketamine intravenous analgesic pump on postoperative pain and psychological status in postpartum women following cesarean section.</p><p><strong>Methods: </strong>A comprehensive retrospective evaluation was conducted at our institution from October 2021 to July 2023, including 168 patients who underwent cesarean delivery. The observation group (n = 82) received esketamine via an intravenous analgesic pump, while the control group (n = 86) received traditional analgesic therapy. Data collected included demographic information, surgical details, postoperative pain (assessed using the Visual Analog Scale, VAS), psychological status (assessed using the Edinburgh Postnatal Depression Scale, EPDS), recovery metrics, and adverse reactions.</p><p><strong>Results: </strong>The observation group demonstrated consistently lower VAS scores at all postoperative time points compared to the control group, indicating superior pain control. EPDS scores were significantly lower in the observation group at 3, 5, and 14 days postoperatively, suggesting better psychological outcomes. The incidence of postpartum depression was also lower in the observation group at 3, 5, and 14 days. Recovery metrics such as time to first ambulation, first flatus, and initiation of lactation were significantly improved in the observation group. There were no significant differences in the incidence of adverse reactions between the groups.</p><p><strong>Conclusions: </strong>The use of the Esketamine Intravenous Analgesic Pump significantly reduces postoperative pain and the incidence of postpartum depression within the first 14 days. It promotes early recovery and breastfeeding in postpartum women without significant adverse reactions, making it a valuable addition to postoperative care.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"144"},"PeriodicalIF":1.6,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of previous gastrectomy on postoperative bile leakage after laparoscopic liver resection.","authors":"Takao Ide, Kotaro Ito, Tomokazu Tanaka, Hirokazu Noshiro","doi":"10.1186/s12893-025-02873-1","DOIUrl":"10.1186/s12893-025-02873-1","url":null,"abstract":"<p><strong>Background: </strong>Postoperative bile leakage (POBL) is a common cause of major morbidity following liver resection. Although the use of laparoscopy for liver surgery has expanded rapidly, POBL has been poorly described in patients undergoing laparoscopic liver resection (LLR). This study aimed to identify the risk factors for POBL after LLR.</p><p><strong>Methods: </strong>We enrolled 510 consecutive patients who underwent LLR for hepatic tumors between January 2009 and December 2023. POBL was defined according to the International Study Group of Liver Surgery, and its incidence, consequences, clinicopathological factors, and surgical details were evaluated retrospectively. Risk factors for POBL were determined using a multivariable logistic regression analysis.</p><p><strong>Results: </strong>POBL occurred in nine patients (1.8%). POBL was significantly associated with advanced age (81 vs. 72 years, p = 0.005), history of gastrectomy (3/9 vs. 25/501, p = 0.002), high incidence of postoperative complications (9 vs. 26, p = 0.001), and prolonged hospital stay (57 vs. 8 days, p = 0.001). In the multivariable analysis, POBL was significantly associated with a history of gastrectomy (OR 7.71, 95% CI 1.744-34.043, p = 0.007). In the management of POBL, all patients were successfully treated with percutaneous drainage alone or with additional treatment using endoscopic nasobiliary drainage.</p><p><strong>Conclusion: </strong>Previous gastrectomy was an independent risk factor for POBL in patients undergoing LLR.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"139"},"PeriodicalIF":1.6,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11974140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the implementation effect of the operating room nursing safety management model based on Heinrich's law.","authors":"Yanru Wu, Mengmin Jing, Haiqin Yang, Juan Liu, Tiantian Zhang, Hui Zhu, Yajuan Yang, Chunyan Gao","doi":"10.1186/s12893-025-02877-x","DOIUrl":"10.1186/s12893-025-02877-x","url":null,"abstract":"<p><strong>Objective: </strong>The study evaluates the clinical value of the operating room nursing safety management model based on Heinrich's law.</p><p><strong>Methods: </strong>A quasi-experimental design with a historical control group was conducted at Changzheng Hospital. A total of 240 surgical patients (pre-intervention: n = 120, December 2021-2022; post-intervention: n = 120, January-December 2023) were recruited via convenience sampling. The intervention included standardized protocols, mobile nursing systems, electronic specimen labeling, and equipment management. Quantitative outcomes were analyzed using χ² tests (adverse events), independent t-tests (nursing competency scores), and logistic regression (risk factors). Patient satisfaction was assessed via a validated self-report questionnaire.</p><p><strong>Results: </strong>The results showed a significant reduction in the incidence of operating room nursing safety accidents and a significant improvement in the specific nursing, identification, management of specimens, health education, safety awareness and operational skills of the nursing staff after the implementation of the operating room nursing safety management model based on Heinrich's law (P < 0.05).The management model implemented in the operating room had a positive impact on nursing safety, as evidenced by the significant improvement in patient satisfaction (P < 0.05). Logistic multifactorial regression analysis identified several key factors that affect nursing care safety in the operating room, including the nursing staff's business ability, legal awareness, the operating room environment, and the management system.</p><p><strong>Conclusion: </strong>The Heinrich's law-based model effectively enhances perioperative safety by reducing errors, improving nursing competency, and increasing patient satisfaction. Clinically, we recommend integrating standardized protocols with mobile alert systems, prioritizing staff training on legal and technical skills, and optimizing equipment workflows. Future studies should validate these findings in multicenter trials and assess long-term cost-effectiveness.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"141"},"PeriodicalIF":1.6,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of side-to-side anastomosis vs. end-to-end anastomosis in NOSES operation for left colon cancer: a retrospective study.","authors":"Jintuan Huang, Jianchao Wu, Sifu Fang, Jinmei Huang, Weili Chen, Zhimin Shi","doi":"10.1186/s12893-025-02837-5","DOIUrl":"10.1186/s12893-025-02837-5","url":null,"abstract":"<p><strong>Objective: </strong>To analyze and compare the application and efficacy of side-to-side anastomosis and end-to-end anastomosis in natural orifice specimen extraction surgery (NOSES) NOSES operation for left colon cancer.</p><p><strong>Methods: </strong>A retrospective analysis of 69 patients in our hospital from February 2018 to February 2022 who underwent NOSES for left colon tumors. The observation group was performed with side-to-side anastomosis (Overlap). For digestive tract reconstruction, the control group was anastomosed by end-to-end anastomosis; the intraoperative and postoperative conditions and complications were compared between the two groups.</p><p><strong>Results: </strong>There was no significant difference in operation time and intraoperative blood loss between the two groups (P > 0.05). However, the intraoperative anastomosis time in the observation group was significantly shorter than that in the control group (P < 0.001). Additionally, there was no significant difference in the time of first exhaustion, defecation time, degree of patency of defecation, frequency of defecation, postoperative hospital stays and postoperative pain between the two groups (P > 0.05). Furthermore, the overall incidence of postoperative complications did not show a significant difference (P > 0.05).</p><p><strong>Conclusions: </strong>In the NOSES surgery of left colon cancer, both side-to-side anastomosis (Overlap) and end-to-end anastomosis yielded comparable intraoperative and postoperative conditions and complications, but the side-to-side anastomosis (Overlap) method was simpler operation-wise and had a shorter intraoperative anastomosis time. As such, this method is the preferred anastomosis method when NOSES for colorectal cancer is carried out in primary hospitals.</p><p><strong>Trial registration number: </strong>ChiCTR1900026104 (2019-09-21).</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"142"},"PeriodicalIF":1.6,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endovascular treatment of intracranial blood blister-like aneurysms with the Willis covered stent: a case series.","authors":"Yazhou Jin, Xinbin Guo, Zhen Chen, Sheng Guan","doi":"10.1186/s12893-025-02874-0","DOIUrl":"10.1186/s12893-025-02874-0","url":null,"abstract":"<p><strong>Background and purpose: </strong>To evaluate the safety, feasibility, and effectiveness of the Willis covered stent (WCS) in treating blood blister-like aneurysms (BBAs).</p><p><strong>Materials and methods: </strong>Twenty-one consecutive patients with BBAs treated with the WCS were identified between July 2017 and July 2022. The demographic, clinical, and angiographic data and procedural-related complications were collected from the medical records and the operative reports.</p><p><strong>Results: </strong>The present study included six men and fifteen women, with a mean age of 51.6 years (31-70 years). The immediate postoperative angiography demonstrated that the complete occlusion rate was 100%, with no endoleak. Ophthalmic artery (OA) occlusion occurred in five patients (23.8%). One patient developed delayed stent thrombosis on the third postoperative day. The mean angiographic follow-up time was 9.2 months (range 3-21 months). All twenty-one BBAs were occluded entirely, and the patency of the parent arteries was preserved. No aneurysm rupture or recurrence was found, and no retreatment was needed. Two patients developed mild to moderate asymptomatic in-stent stenosis. The clinical follow-up time was 20.0 months (range 15-33 months). Twenty patients had an mRS score of zero, and one had an mRS score of one.</p><p><strong>Conclusions: </strong>Our series indicates that treating BBAs with WCSs was relatively safe and efficacious. However, the incidence of stent delivery failure and complications should not be neglected.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"140"},"PeriodicalIF":1.6,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of drain placement in post-bariatric surgery bleeding and leak detection: Palestinian main center experience (2017-2021).","authors":"Fatima Az-Zahra Mohammed Thawabteh, Taqwa Riad Abu Ghanieh, Osama J Makhamreh, Khaled Alshawwa, Bayan Fathi Al-Qtishat, Ruba Maher Salameh, Omar Abu Zaydeh","doi":"10.1186/s12893-025-02884-y","DOIUrl":"10.1186/s12893-025-02884-y","url":null,"abstract":"<p><strong>Introduction: </strong>Bariatric surgery, such as sleeve gastrectomy (SG) and gastric bypass, is a common option for weight loss in patients with obesity and metabolically ill individuals. However, complications like bleeding and leaks can occur. Surgeons often use intraoperative drains to detect these issues, but their effectiveness is debated due to conflicting evidence. Our study aims to evaluate the benefits of intra-abdominal drains in detecting postoperative bleeding and leaks.</p><p><strong>Methods: </strong>This is a retrospective cross-sectional study, with data from 494 patients who underwent bariatric surgery at the primary bariatric center in Palestine, between 2017 and 2021. Patient demographics, comorbidities, surgical complications, and drain usage were collected, managed, and analyzed using SPSS.</p><p><strong>Results: </strong>The study included 494 patients, predominantly females (69.0%) with a median age of 39.5 years. Sleeve gastrectomy was the most common procedure (78.1%). Postoperative complications occurred in 3.0% of patients, with bleeding being the most prevalent (1.4%). Drain placement was routine (82.0%), but no significant correlation was found between drain output volume and signs of bleeding, such as heart rate and blood pressure. However, a weak inverse correlation was observed between volume for bloody drain character and hemoglobin levels on the first postoperative day.</p><p><strong>Conclusion: </strong>Drains are commonly used in bariatric surgery; however, their effectiveness in detecting complications like bleeding and leaks remains uncertain. There was no association between drain output volume and signs of bleeding and leak complications, and the clinical assessment, especially the vital signs, is the most effective method in identifying postoperative issues.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"138"},"PeriodicalIF":1.6,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11974030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcome of chronic haematogenous osteomyelitis of the femur or tibia in adults using selective segmental osteotomy and induced membrane technique.","authors":"Yi Wang, Junyi Li, Xijiao Zhang, Xiaoyong Yang, Muguo Song, Kehan Lv, Yongqing Xu, Jian Shi","doi":"10.1186/s12893-025-02865-1","DOIUrl":"10.1186/s12893-025-02865-1","url":null,"abstract":"<p><p>Identification of infected lesions in chronic haematogenous osteomyelitis (CHOM) is challenging due to no distinct boundary. The optimal methods of debridement and bone reconstruction remain controversial. The aim of this study was to evaluate the clinical efficacy of selective segmental osteotomy with induced membrane technique in adult CHOM patients of the femur or tibia. The patients who underwent a staged surgery of induced membrane technique were include. In the first stage. the patients were treated by selective segmental osteotomy for debridement according to imaging result preoperatively. In the second stage, spacer removing, fixation and bone grafting were performed sequentially. 16 patients were included. The mean age was 34.7 years. After debridement, the mean bone defects length was 7.9 cm. At a mean followed-up of 30.5 months, no infection recurrence in all patients. At the last follow-up, all patients achieved bone union on average at 6.9 months. Visual Analogue Scale (VAS) score, Self-rated Anxiety Scale (SAS) score, and Hospital for Special Surgery (HSS) score improved at 3 months after the second stage of surgery and at the final follow-up compared with initial admission (P < 0.05). For adult patients with CHOM of femur and tibia, selective segmental osteotomy with induced membrane technique is a feasible and effective treatment method.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"137"},"PeriodicalIF":1.6,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11971898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}