BMC Surgery最新文献

{"title":"Comparison of laparoscopic versus robot-assisted sugery for rectal cancer after neo-adjuvant therapy: a large volume single center experience.","authors":"Heyuan Zhu, Jingyu Zou, Hongfeng Pan, Ying Huang, Pan Chi","doi":"10.1186/s12893-025-02764-5","DOIUrl":"10.1186/s12893-025-02764-5","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to assess the short- and long-term outcomes of rectal cancer patients undergoing robotic versus laparoscopic surgery after receiving neo-adjuvant therapy. There is a lack of clarity on this topic, necessitating a comprehensive comparison.</p><p><strong>Method: </strong>Between January 2017 and December 2021, consecutive patients who underwent laparoscopic and robotic rectal resection at a major public medical center were enrolled. All participants received neo-adjuvant chemoradiotherapy (nCRT) before surgery. The primary objective of this study was to assess the sphincter preservation rate and the rate of conversion to open surgery, using propensity score matching (PSM) analysis. Secondary endpoints included 5-year disease-free survival (DFS), 5-year overall survival (OS), short-term postoperative complications, long-term oncological prognosis, and the occurrence of low anterior resection syndrome (LARS).</p><p><strong>Result: </strong>A total of 575 patients diagnosed with rectal cancer participated in the cohort study, with 183 individuals undergoing robotic surgery and 392 undergoing laparoscopic surgery. Patients in the robotic group tended to be younger and had higher ypT, cT, and cN stages, lower tumor locations, and higher rates of extramural vascular invasion (EMVI) and circumferential resection margin (CRM) positivity. PSM resulted in 183 patients in the robotic group and 187 in the laparoscopic group. We found a higher sphincter preservation rate in robotic group compared with laparoscopic group (92.9% vs. 86.1%, P = 0.033), with no significant difference in conversion to open surgery(P > 0.05). The robotic group had a higher incidence of postoperative chylous ascites (4.9% vs. 1.1%, P = 0.029) and potentially lower sepsis occurrence (0% vs. 1.6%, P = 0.085). No significant differences were observed in long-term oncological prognosis or 5-year survival rates (P > 0.05). The median survival time for each group was 34 months. Subgroup analysis of 76 rectal cancer patients who underwent intersphincteric resection (ISR) surgery indicated that those who selected robotic surgery had higher cN and cT stages. Furthermore, no statistically significant differences were observed in short-term and long-term clinical outcomes, LARS, OS time, and DFS time between the two surgical modalities. The primary outcomes of interest, specifically the rate of sphincter preservation and the rate of conversion to open laparotomy, showed no significant differences.</p><p><strong>Conclusion: </strong>Robotic surgery for rectal cancer, following preoperative nCRT, demonstrates comparable technical safety and oncological outcomes to laparoscopic surgery. Further comprehensive studies are needed to to confirm the potential advantages of robotic surgical interventions.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"98"},"PeriodicalIF":1.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11899483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascularized fibular epiphyseal transfer for biological reconstruction of bone defects following resection in children with proximal humeral sarcoma.","authors":"Jun Li, Xianzhe Tang, Lu Wang, Tang Liu","doi":"10.1186/s12893-025-02828-6","DOIUrl":"10.1186/s12893-025-02828-6","url":null,"abstract":"<p><strong>Background: </strong>The functional reconstruction of bone defects following resection of proximal humerus tumors in children poses a significant challenge. This study utilized vascularized fibular epiphyseal transfer for proximal humerus reconstruction to evaluate the outcome, complications, and survival rates.</p><p><strong>Methods: </strong>In this study, we conducted a retrospective analysis of 13 pediatric patients who underwent vascularized fibular epiphyseal transfer for biological reconstruction following oncologic resection of the proximal humerus between 2019 and 2021. All patients received adequate preoperative preparation and evaluation, and complications were meticulously recorded. Regular functional follow-ups and imaging evaluations were performed.</p><p><strong>Results: </strong>A total of 13 patients with an average age of 9.8 years were included in this study. The average length of the humerus defect after surgical resection was 13.7 cm (9.4-17.8 cm). Delayed wound healing was observed in 2 patients, and one patient experienced brief common peroneal nerve palsy. There were 3 cases of graft fracture, all of which occurred within 1 year after operation. These cases were successfully managed through the application of draping plaster or brace fixation. The mean follow-up period was 39.8 months (ranging from 19 to 57 months). The mean Musculoskeletal Tumor Society (MSTS) score was 21.5 (18-24). All patients reported no persistent pain.</p><p><strong>Conclusion: </strong>In conclusion, we assert that vascularized fibular epiphyseal transfer provides a reliable and promising option for reconstruction in pediatric patients undergoing proximal humerus tumor resection surgery. Graft fractures were the most prevalent complication, emphasizing the importance of cautionary measures to prevent falls or trauma. However, further validation through increased case numbers and extended follow-up periods is necessary.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"95"},"PeriodicalIF":1.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the efficacy of a prophylactic increasing blood pressure before the end of surgery to reduce postoperative bleeding after gastrectomy: a propensity score-matched analysis.","authors":"Guangxu Zhu, Shengjie Zhou, Qihang Sun, Xuren Lu, Qingshun Zhu, Xin Yin, Lei Yu, Jianjun Qu, Xiaomin Lang","doi":"10.1186/s12893-025-02826-8","DOIUrl":"10.1186/s12893-025-02826-8","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the efficacy of reducing post-gastrectomy hemorrhage by increasing blood pressure at the end of gastric surgery and to evaluate whether this clinical intervention affects the stability of patients' postoperative circulatory system.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 499 patients who underwent radical gastrectomy under general anesthesia at our center between January 2023 and January 2024. After 1:1 propensity score matching, the experimental group comprised 157 patients whose operation cavities were examined after increasing blood pressure before the end of gastrectomy, while the control group included 157 patients whose operation cavities were examined using routine procedures without increasing blood pressure.</p><p><strong>Results: </strong>The incidences of total postoperative bleeding (0% vs. 3.82%, P = 0.013) and early postoperative bleeding (0% vs. 2.55%, P = 0.044) were significantly lower in the experimental group compared to the control group. There were no significant differences between the two groups in delayed bleeding (0% vs. 1.23%, P = 0.156), systolic blood pressure immediately upon returning to the ward (121.02 ± 18.196 vs. 120.34 ± 21.664, P = 0.795), systolic blood pressure 48 h post-surgery (125.04 ± 16.242 vs. 126.23 ± 17.048, P = 0.529), diastolic blood pressure immediately upon returning to the ward (83.83 ± 11.978 vs. 84.75 ± 12.422, P = 0.506), diastolic blood pressure 48 h post-surgery (74.69 ± 9.773 vs. 75.76 ± 10.605, P = 0.353), heart rate immediately upon returning to the ward (74.31 ± 11.610 vs. 75.15 ± 11.660, P = 0.522), or heart rate 48 h post-surgery (80.49 ± 12.267 vs. 79.11 ± 10.969, P = 0.293). Additionally, there were no statistically significant differences between the two groups regarding anastomotic fistula, intestinal obstruction, postoperative pneumonia, reoperation, mortality, combined organ resection, or postoperative hospital stay (P > 0.05).</p><p><strong>Conclusion: </strong>Increasing blood pressure before the end of gastrectomy can effectively reduce the incidence of primary postoperative hemorrhage without affecting the stability of the perioperative circulatory system.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"93"},"PeriodicalIF":1.6,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892180/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of pulmonary infection on thoracoscopic surgery outcomes in children with CPAM: a retrospective study.","authors":"Cui-Xia Yuan, Chun Wu, Zheng-Xia Pan, Yong-Gang Li","doi":"10.1186/s12893-025-02827-7","DOIUrl":"10.1186/s12893-025-02827-7","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary infection is a common clinical complication in children with congenital pulmonary airway malformation (CPAM). Surgical intervention has been proven effective in managing this condition. We aim to evaluate the impact of pulmonary infection on the outcomes of total thoracoscopic procedures in children with CPAM.</p><p><strong>Methods: </strong>This was a single-center retrospective study. CPAM patients who underwent total thoracoscopic surgery at a tertiary care center from January 2013 to December 2023 were divided into three groups based on pulmonary infection status: non-infection (NI), hidden infection (HI), and pulmonary infection (PI). Clinical characteristics and operation-related outcomes were compared among the groups.</p><p><strong>Results: </strong>A total of 154 children with CPAM who underwent thoracoscopic surgery were categorized into three groups based on pulmonary infection: the NI group (27 cases), HI group (56 cases), and PI group (71 cases). The conversion rate to thoracotomy was 14.8%, 23.2%, and 29.2% respectively across the three groups. 116 cases were successfully completed thoracoscopically. There were no significant differences in gender distribution among the three groups (p > 0.05), but statistically significant (p < 0.05) in age and weight. Significant differences emerged in operative time and blood loss (p < 0.05), but no significant variations were found in transfusion requirements, chest tube duration, ventilator use duration, or hospital stay length (p > 0.05). In postoperative pulmonary complications, a statistically significant difference was found regarding pneumothorax incidence among all three groups (p < 0.05), whereas no significant differences (p > 0.05) emerged concerning atelectasis or pneumonia incidences across these cohorts.</p><p><strong>Conclusions: </strong>Pulmonary infection is the most prevalent complication in CPAM and exhibits a high rate of hidden infections, thereby complicating surgical intervention and increasing associated risks. Early thoracoscopic intervention prior to infection manifestation can optimize surgical outcomes and reduce associated complications.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"94"},"PeriodicalIF":1.6,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of metronidazole in reducing pain after hemorrhoidectomy: a meta-analysis of randomized controlled trials.","authors":"Hui Dong, Wen-Xing Chen, Yue-Juan Li, Deng-Chao Wang","doi":"10.1186/s12893-025-02819-7","DOIUrl":"10.1186/s12893-025-02819-7","url":null,"abstract":"<p><strong>Objective: </strong>Pain is a significant issue in post-hemorrhoidectomy. Metronidazole is being explored as an adjunctive pain management option. This meta-analysis of randomized controlled trials (RCTs) assesses metronidazole's effectiveness and safety compared to a placebo post-hemorrhoidectomy, aiming to provide evidence-based pain management guidance.</p><p><strong>Method: </strong>We conducted a systematic search of the Cochrane Library, Embase, PubMed, Web of Science, and ClinicalTrials.gov for RCTs comparing metronidazole to placebo after hemorrhoidectomy, covering the period from database inception to July 21, 2024. After screening per inclusion/exclusion criteria, study quality was assessed using Cochrane Handbook's risk of bias tool (version 5.1.0). The meta-analysis was conducted using RevMan 5.3 software, the quality of outcome indicators was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system, and trial sequential analysis (TSA) was employed to verify the adequacy of the sample size.</p><p><strong>Results: </strong>A total of 9 RCTs were included. The meta-analysis results showed that the pain scores on the first day post-operation [MD=-1.07, 95% CI (-1.85, -0.30), P = 0.006], the second day post-operation [MD=-1.72, 95% CI (-2.62, -0.81), P = 0.0002], the seventh day post-operation [MD=-1.73, 95% CI (-2.70, -0.76), P = 0.0005], and the fourteenth day post-operation [MD=-1.80, 95% CI (-2.67, -0.94), P < 0.0001] in the metronidazole group were lower than those in the placebo group. Additionally, the rate of additional analgesia was reduced [RR = 0.48, 95% CI (0.27, 0.84), P = 0.01]. No statistically significant differences were found between the metronidazole and placebo groups in terms of the overall incidence of complications [RR = 0.69, 95% CI (0.41, 1.16), P = 0.16] and time to return to normal activities [MD=-1.69, 95% CI (-6.58, 3.20), P = 0.50]. Sensitivity analysis indicated that the results for pain scores on the first day post-operation were unstable. High heterogeneity was observed in pain scores on the first, second, seventh, and fourteenth days post-operation, as well as in the time to return to normal activities. The TSA indicated that the sample size for the primary outcome measures had achieved the required information size (RIS), supporting the strength and dependability of the meta-analysis findings.</p><p><strong>Conclusion: </strong>Metronidazole may be effective and safe in reducing postoperative pain in patients undergoing hemorrhoidectomy. However, due to the limitations of this study, further verification is needed from future large-sample, multi-center, well-designed high-quality RCTs.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"92"},"PeriodicalIF":1.6,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11889878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical progression following acellular dermal matrix use for volume replacement after breast-conserving surgery.","authors":"JinAh Kwon, Jung Hee Byon, Byung Kyun Ko, Jin Sung Kim, Minseo Bang","doi":"10.1186/s12893-025-02821-z","DOIUrl":"10.1186/s12893-025-02821-z","url":null,"abstract":"<p><strong>Background: </strong>The cosmetic outcomes of breast-conserving surgery (BCS) have recently gained increasing attention, and surgeons are exploring the use of the acellular dermal matrix (ADM) as a safe and effective method of breast reconstruction. This study evaluated the clinical progress of patients with breast cancer following the application of sheet-type ADM for breast reconstruction after BCS.</p><p><strong>Methods: </strong>This retrospective study included 137 patients who underwent BCS using ADM at a single center between October 2019 and October 2021. During surgery, sheet-type ADM was folded and inserted into the excised defects. Complications and cancer recurrence were evaluated during surveillance follow-up until December 2023, and maintenance of the inserted ADM was quantitatively compared using volume analysis of the first and last follow-up computed tomography (CT).</p><p><strong>Results: </strong>Of the 137 evaluated patients, 16 (11.6%) had minor complications, and 17 (12.4%) underwent biopsy during the surveillance period. One patient was diagnosed with recurrence. ADM volume was measured in 55 patients. The mean volume reduction between the first and last CT scans was 1.81 ± 2.06 cm³ (a decrease of 17.42 ± 19.82%), which was statistically significant (p < 0.001).</p><p><strong>Conclusions: </strong>The insertion of ADM after BCS is a safe and effective method for addressing volume defects, even though a slight reduction occurs in ADM volume.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"91"},"PeriodicalIF":1.6,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881489/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical effect analysis of unilateral percutaneous vertebral cement distribution in the repair of osteoporotic thoracolumbar vertebral compression fractures.","authors":"Liu Yuntao, Abuduwupuer Haibier, Aiben Kayierhan, Ma Liang, Yimuran Abudukelimu, Alimujiang Aximu, Tuerhongjiang Abudurexiti, Meng Xiangyu","doi":"10.1186/s12893-025-02820-0","DOIUrl":"10.1186/s12893-025-02820-0","url":null,"abstract":"<p><strong>Background: </strong>Osteoporotic vertebral fractures and their complications pose increasing risks to the elderly. The purpose of this study was to evaluate the clinical efficacy of unilateral percutaneous vertebroplasty in patients with osteoporotic vertebral compression fractures (OVCF) by assessing postoperative cement distribution.</p><p><strong>Objective: </strong>This study aimed to investigate the impact of cement distribution on the efficacy of vertebral compression fracture repair to provide effective preventive and therapeutic measures, prevent postoperative vertebral re-fracture, and improve surgical outcomes.</p><p><strong>Methods: </strong>A total of 170 patients who underwent unilateral percutaneous vertebroplasty at our hospital from January 2020 to December 2022 were selected. Based on the postoperative X-ray cement distribution morphology, they were divided into the good distribution group (n = 87) and the poor dispersion group (n = 83). The basic information of patients, surgery-related indicators including operation time, total hospitalization costs, postoperative hospitalization time, cement injection volume, visual analog scale (VAS) for back pain, Oswestry Disability Index (ODI) for back pain, vertebral height restoration rate, local kyphotic angle of the vertebra, and incidence of re-fracture of injured and adjacent vertebrae were compared between the two groups, and the follow-up results of all patients were recorded.</p><p><strong>Results: </strong>There were no significant differences in age, gender, body mass index, fracture days, menopausal age of female patients, bone density T value, medical history, smoking history, alcohol history, and surgical segments between the two groups (P > 0.05). The VAS scores for back pain at 1 month and 1 year postoperatively were significantly lower in the good distribution group than in the poor dispersion group, with statistical significance (P < 0.05). The good distribution group had a significantly lower incidence of re-fracture of injured vertebrae and overall fracture incidence than the poor dispersion group (P < 0.05). There were no statistically significant differences in operation time, cement dosage, cement leakage, postoperative hospitalization time, adjacent vertebral fractures, postoperative vertebral height restoration rate, VAS scores for back pain at preoperative and 1 week postoperative, and ODI at preoperative, 1 week, 1 month, and 1 year postoperative between the two groups (P > 0.05).</p><p><strong>Conclusion: </strong>Compared with the poor dispersion group, patients in the cement distribution group achieved better short-term clinical efficacy, and long-term prognosis effects are still under observation. Moreover, the cement good distribution group significantly reduced the incidence of re-fracture of injured vertebrae and overall fracture incidence, thereby achieving better surgical outcomes.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"90"},"PeriodicalIF":1.6,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy in navigated percutaneous sacroiliac screw fixation: a systematic review and meta-analysis.","authors":"R A Haveman, L Buchmann, P C Haefeli, F J P Beeres, R Babst, B-C Link, B J M van de Wall","doi":"10.1186/s12893-025-02813-z","DOIUrl":"10.1186/s12893-025-02813-z","url":null,"abstract":"<p><strong>Introduction: </strong>Percutaneous sacroiliac screw fixation of pelvic fragility fractures is increasingly being used to maintain mobility and reduce pain in the elderly patient population. Traditionally, this is performed using 2D fluoroscopy. Several newer, navigated techniques have emerged that may further facilitate this procedure. It, however, remains unclear whether there is a benefit regarding accuracy, radiation exposure and complications of these new navigation techniques when compared to the traditional 2D fluoroscopy.</p><p><strong>Methods: </strong>A systematic review and meta-analysis were performed. PubMed, CENTRAL and Embase were searched for both randomized controlled trials and observational studies comparing new navigation techniques to 2D fluoroscopy for percutaneous sacroiliac screw fixation. Effect estimates were pooled (random effects) and presented as odds ratio, mean difference and standardized mean difference with a 95% confidence interval.</p><p><strong>Results: </strong>19 studies were included. The 2D fluoroscopy group had 642 patients and the new navigation group 663 patients. Accuracy was significantly higher in the new navigation group (OR 2.44, 95% CI 1.53-3.90), especially O-Arm, 3D CT and Robotic navigation. On average, accuracy was 82% in the 2D group and 92% in the new navigation group, which was significant. Also, fluoroscopy time (MD 71.89 s, 95% CI 51.37-92.41) and frequency (MD 17.22 images in total, 95% CI 7.73-26.70) were significantly reduced in the new navigation group. Complications are acceptably low, however, poorly reported in both groups.</p><p><strong>Conclusion: </strong>This meta-analysis demonstrated a higher accuracy, lower fluoroscopic frequency and time for new navigation techniques compared to 2D fluoroscopy. More advanced navigation techniques, such as 3D CT and robotic navigation, appeared to be even better.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"89"},"PeriodicalIF":1.6,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of a clinical prediction model for dialysis-requiring acute kidney injury following heart transplantation: a single-center study from China.","authors":"Shirui Qian, Bingxin Cao, Ping Li, Nianguo Dong","doi":"10.1186/s12893-025-02817-9","DOIUrl":"10.1186/s12893-025-02817-9","url":null,"abstract":"<p><strong>Objectives: </strong>This study seeks to construct and internally validate a clinical prediction model for predicting new-onset dialysis-requiring acute kidney injury (AKI) following heart transplantation (HT).</p><p><strong>Methods: </strong>The Kaplan-Meier survival analysis and log-rank test were utilized for conducting the survival analysis. A clinical prediction model was developed to predict postoperative dialysis-requiring AKI, based on a logistic regression model and likelihood ratio test with Akaike Information Criterion. The performance of the prediction model was assessed using C-index, receiver operating characteristic curves, calibration curves, Brier score, and the Spiegelhalter Z-test. Clinical utility was evaluated using decision curve analysis and clinical impact curves.</p><p><strong>Results: </strong>This study included a total of 525 patients who underwent orthotopic HT in the single center located in Wuhan, China between January 2015 and December 2021, with 16.57% developing postoperative dialysis-requiring AKI. Patients who experienced postoperative dialysis-requiring AKI exhibited a lower overall survival rate. All enrolled participants were randomly allocated into derivation (n = 350) and validation (n = 175) cohorts at a ratio of 2:1. The final prediction model comprised six indicators: diabetes, stroke, gout, prognostic nutritional index, estimated glomerular filtration rate, and cardiopulmonary bypass duration. The prediction model demonstrated outstanding discrimination (C-index of 0.792 in the derivation cohort and 0.834 in the validation cohort) as well as calibration performance, indicating strong concordance between observed and nomogram-predicted probabilities. Subgroup analysis based on age, preoperative serum creatine levels, and year of surgery also exhibited robust discrimination and calibration capabilities.</p><p><strong>Conclusions: </strong>Dialysis-requiring AKI following HT is associated with poor clinical prognosis. The prediction model, comprising six indicators, is capable of predicting dialysis-requiring AKI following HT. This prediction model holds promise in assisting both patients and clinicians in forecasting postoperative renal failure, thereby improving clinical management.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"88"},"PeriodicalIF":1.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Main features and treatments of cervical cysts in children from a single-center experience.","authors":"Nian Sun, Wei Pang, Xuexi Zhang, Yanzhen Li, Qiaoyin Liu, Zhiyong Liu, Xiaodan Li, Junlong Tan, Shengcai Wang, Xin Ni","doi":"10.1186/s12893-025-02791-2","DOIUrl":"10.1186/s12893-025-02791-2","url":null,"abstract":"<p><strong>Background: </strong>The cervical cysts is one of the most common children ailments an ENT surgeon encountered, which often begins with painless masses in the neck. The present study summarizes main clinical features of various types of children cervical cysts and discusses the possible approaches and associated complications, with an aim to improve the diagnosis and treatment of this pediatric disease.</p><p><strong>Methods: </strong>We retrospectively analyzed the clinical data of patients admitted with cervical cyst to Beijing Children's Hospital, Capital Medical University from January 2018 to December 2023. Analysis focused on the clinical presentation, medical imaging, surgical approach, treatment-related complications as well as disease recurrence.</p><p><strong>Results: </strong>The main self-reported symptom at first admission was painless masses at neck and submandibular space accompanied by sleep apnea, laryngeal stridor, odynophagia or hoarse voice. Three hundred and eighty-four patients received cervical ultrasound examination, whereas 92 patients were subjected to cervical MRI. The median of cysts size recorded by medical imaging was 1.7 cm*1.0 cm*1.6 cm. The median operation duration was 55 min. Histology of removed cysts indicated five main pathological categories including thyroglossal duct cyst (TGDC), branchial cleft cyst (BCC), dermoid cyst (DC), lymphatic malformation (LM) and bronchogenic cyst (BC). The most frequent postsurgical complication was dysphagia and inflammatory wound swelling. Seven patients inflicted with relapses before further treatment.</p><p><strong>Conclusions: </strong>Comprehensive evaluation including medical history, physical examination, ultrasound and MRI imaging of cervical spaces is required to assure the proper diagnosis of cervical cysts in children. Surgical removal remains the major modality for disease control. Majority of postsurgical complications are attributed to transitional injury of blood vessels or nerves. Recurrence of cysts is commonly associated with patients with TGDC and LM.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"25 1","pages":"82"},"PeriodicalIF":1.6,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869738/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143532038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}