Indian Journal of Otolaryngology and Head and Neck Surgery最新文献

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Anthropometric Measurement of Human External Ear: A Single-Center Experiment in a Pediatric Saudi Population. 人类外耳的人体测量测量:沙特儿童人群的单中心实验。
IF 0.5
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-05 DOI: 10.1007/s12070-025-05633-y
Khaled Alhussinan, Hisham Almousa, Abdullah Alassaf, Bader Alwhaibi, Renad Alfirm, Ahmed Alolaywi, Hassan Assiri, Badi Aldosari
{"title":"Anthropometric Measurement of Human External Ear: A Single-Center Experiment in a Pediatric Saudi Population.","authors":"Khaled Alhussinan, Hisham Almousa, Abdullah Alassaf, Bader Alwhaibi, Renad Alfirm, Ahmed Alolaywi, Hassan Assiri, Badi Aldosari","doi":"10.1007/s12070-025-05633-y","DOIUrl":"10.1007/s12070-025-05633-y","url":null,"abstract":"<p><p>Objectives: Anthropometry, the study of human anatomy through dimensional analysis, is essential for standardizing human anatomy. This study aimed to measure external ear anthropometric variables in healthy pediatric Saudi individuals using a novel, photo-based technique. Methods: A cross-sectional study was conducted among children aged 1-17 years attending the otorhinolaryngology clinic at a tertiary hospital in Saudi Arabia. Data were collected between August 2022 and January 2023. We enrolled 76 participants (148 ears) who met our inclusion criteria. Patients with external ear deformities due to trauma, congenital malformations, previous surgery, or known congenital syndromes were excluded. This study used a software modality to measure the anthropometric variables which required a picture displaying the desired measurement area and a ruler to set the standard distance. Subsequently, all data were extracted using this method. Results: Of 76 enrolled participants, 52 (68.4%) were male and 24 (31.6%) female. The average age of the included participants was 7.71 ± 4.14 years. Significant differences were found in the right and left ear measurements between males and females. Right and left ear lengths, lobular lengths, concha lengths, and concha widths were significantly greater in males than in females. Conclusion: The study results suggest that male children tend to have larger ears than female children. Additionally, the anthropometric ear measurements in the Saudi pediatric population appear to be smaller than those of pediatric patients from other populations.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12070-025-05633-y.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"3056-3064"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of a New Disease Staging System Using CT Scans to Measure Disease Severity in Rhinomaxillary Mucormycosis - An Analytical Study. 评估一种新的疾病分期系统使用CT扫描测量疾病严重程度鼻上颌毛霉菌病-一项分析研究。
IF 0.5
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-12 DOI: 10.1007/s12070-025-05604-3
Varsha Manekar, Nikhil Shastrakar, Abhay Datarkar, Mehak Kataria, Priyanka Shetty
{"title":"Evaluation of a New Disease Staging System Using CT Scans to Measure Disease Severity in Rhinomaxillary Mucormycosis - An Analytical Study.","authors":"Varsha Manekar, Nikhil Shastrakar, Abhay Datarkar, Mehak Kataria, Priyanka Shetty","doi":"10.1007/s12070-025-05604-3","DOIUrl":"10.1007/s12070-025-05604-3","url":null,"abstract":"<p><p>This study aims to evaluate reliability of Manekar et al. system in clinical settings by comparing and correlating it with widely used Lund & Mackay (L-M) system to quantify the severity of rhinomaxillary mucormycosis (RMM). Objectives are (a) To assess the severity of maxillary sinus disease using L-M system. (b) To assess the severity of maxillary sinus disease using Manekar et al. system. (c) To assess the severity of maxillary osteomyelitis using Manekar et al. system (d) To compare the scores of L-M and Manekar et al. system. This retrospective analytical study involved three experts reviewing CT scans of 38 RMM patients. Both Manekar et al. and L-M systems were used to grade the cases. Mean observations were calculated, and the systems were compared using Pearson's chi-squared test and Pearson correlation coefficient (PCC). The Kappa coefficient determined inter-rater reliability and variability. Kappa reliability test for Manekar et al. system showed values of k = 0.92 (left) and k = 0.94 (right), indicating perfect agreement. The correlation between Manekar et al. system and L-M system showed strong positive correlations, with PCC values of <i>r</i> = 0.832 (left) and <i>r</i> = 0.839 (right). A highly significant statistical difference was found between the two systems, as the L-M system assessed maxillary sinus involvement as a single unit, while the Manekar et al. system provided a detailed evaluation. The Manekar et al. system is reliable for evaluating maxillary sinus disease and osteomyelitis. Further research is needed to monitor disease progression and postoperative recovery using Manekar et al. system.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"2905-2911"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Study of Correlation Between Intra-operative Electrically Evoked Stapedial Reflex and Neural Response Telemetry with Maximum Comfort Level in Children with Cochlear Implant. 人工耳蜗患儿术中电诱发镫骨反射和神经反应遥测与最大舒适程度的相关性研究。
IF 0.5
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-11 DOI: 10.1007/s12070-025-05611-4
Priya Dogra, Prem Singh Jat, Sunita Agarwal, Payal Kumbhat
{"title":"A Study of Correlation Between Intra-operative Electrically Evoked Stapedial Reflex and Neural Response Telemetry with Maximum Comfort Level in Children with Cochlear Implant.","authors":"Priya Dogra, Prem Singh Jat, Sunita Agarwal, Payal Kumbhat","doi":"10.1007/s12070-025-05611-4","DOIUrl":"10.1007/s12070-025-05611-4","url":null,"abstract":"<p><p>Psychophysical measurements of T and C-levels are difficult in children. Electrically evoked Stapedial Reflex (eSRT) and Neural Response Telemetry (NRT) is an objective method to measure the same. This study aims to correlate intraoperative eSRT and NRT levels with Maximum Comfort Level (MCL) in children and ascertain its usefulness in programming a cochlear implant. Thirty children undergoing cochlear implant surgery were included. Intra-operative eSRT and NRT was measured using single electrode stimulation on third electrode. After three weeks, implant was switched on and MCL were documented. We observed a statistically significant positive correlation of eSRT (r<sup>2</sup>-0.755) and NRT (r<sup>2</sup>-0.698) with maximum comfort level. Intra-operative eSRT and NRT testing can reliably predict the behavioural MCL, and can be useful for evaluating patients who are difficult to test.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"2952-2956"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Aftermath of the Battle Between Covid-19 & Invasive Fungal Sinusitis: A long Term Prospective Study. Covid-19与侵袭性真菌鼻窦炎之战的后果:一项长期前瞻性研究。
IF 0.5
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-05-31 DOI: 10.1007/s12070-025-05392-w
Nazrin Hameed, Amit Keshri, Ravi Sankar Manogaran, Abhishek Dubey, Kalyana Sundaram Chidambaram, Mohd Aqib, Mohit Sinha, Nidhin Das
{"title":"The Aftermath of the Battle Between Covid-19 & Invasive Fungal Sinusitis: A long Term Prospective Study.","authors":"Nazrin Hameed, Amit Keshri, Ravi Sankar Manogaran, Abhishek Dubey, Kalyana Sundaram Chidambaram, Mohd Aqib, Mohit Sinha, Nidhin Das","doi":"10.1007/s12070-025-05392-w","DOIUrl":"10.1007/s12070-025-05392-w","url":null,"abstract":"<p><p>Corona virus disease 2019 (COVID-19) pandemic saw a surge of invasive fungal sinusitis. This study prospectively followed up these cases to observe the long term sequelae and prognosis in these patients. A prospective, hospital based observational study was conducted at a tertiary referral center amongst 124 patients diagnosed with COVID- 19 associated invasive fungal sinusitis of the paranasal sinuses between April 2021 to September 2021. These patients were treated with surgery and or antifungals depending on the extend of the disease and surgical fitness of the patient and they were prospectively followed up till October 2023 by reviewing the clinical features, symptoms, serial nasal endoscopies and radiological imaging such as computed tomography and magnetic resonance imaging. The overall survival at the end of three months and eighteen months was 79.8% and 72.03% respectively. The most common presenting symptom in the outpatient department was facial pain in 67 patients (72.04%) which improved in only 17.91%. During the follow up period two patients developed progressive disease which required multiple surgeries.Covid-19 related invasive fungal sinusitis patients need judicious follow up for long term to minimise the possibility of progressive disease and associated complications.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"2733-2739"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297082/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Causal Effects Between Anxiety-Depressive and Subjective Tinnitus in Europe: A Bidirectional Mendelian Randomization Study. 欧洲焦虑抑郁与主观性耳鸣之间的因果关系:一项双向孟德尔随机研究。
IF 0.4
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-09 DOI: 10.1007/s12070-025-05618-x
Cheng Zhong, Li-Hua Wang, Ying Dong, Haopeng Zhang, Lin Ji, Yu Guo
{"title":"Causal Effects Between Anxiety-Depressive and Subjective Tinnitus in Europe: A Bidirectional Mendelian Randomization Study.","authors":"Cheng Zhong, Li-Hua Wang, Ying Dong, Haopeng Zhang, Lin Ji, Yu Guo","doi":"10.1007/s12070-025-05618-x","DOIUrl":"10.1007/s12070-025-05618-x","url":null,"abstract":"<p><p>This study aimed to explore the potential causal relationship between anxiety-depression and tinnitus using a bidirectional mendelian randomization (MR) approach. Utilizing genetic data from five UKB datasets, one IEU dataset, one EBI dataset encompassing traits linked to anxiety and depressive states, and tinnitus data sourced from the FinnGen project, we conducted two-sample MR analyses. Instrumental variables were selected based on stringent criteria, including genome-wide significance, clumping to ensure independence, and the exclusion of palindromic Single Nucleotide Polymorphisms and those associated with confounders. The primary MR analysis employed the Inverse Variance Weighted method, supplemented by sensitivity analyses using the Weighted Median and MR-Egger methods, to address potential pleiotropy. MR analyses suggested a genetic correlation between anxiety-depression and an increased risk of tinnitus. These findings were robust across various sensitivity analyses, including MR-Egger and MR-PRESSO, which supported the absence of pleiotropy and outliers. No evidence of reverse causality was found, strengthening the argument regarding the unidirectional influence of psychological factors on tinnitus. Our results indicate that a genetic predisposition to anxiety and depression can significantly enhance the risk of developing tinnitus. This finding the integration of psychological assessments and interventions in the management of tinnitus, highlighting the importance of addressing mental health components in auditory conditions. Further studies are required to explore these associations in more diverse populations and refine the mechanisms underlying these relationships.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12070-025-05618-x.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"2979-2991"},"PeriodicalIF":0.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hansen's Disease Presenting as Perichondritis: A Rare ENT Diagnostic Challenge - Case Series. 汉森氏病表现为软骨膜炎:罕见的耳鼻喉科诊断挑战-病例系列。
IF 0.5
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-12 DOI: 10.1007/s12070-025-05740-w
Vijay Bohra, Sween Banger, Mahesh Ravunnikutty, Sunil Goyal
{"title":"Hansen's Disease Presenting as Perichondritis: A Rare ENT Diagnostic Challenge - Case Series.","authors":"Vijay Bohra, Sween Banger, Mahesh Ravunnikutty, Sunil Goyal","doi":"10.1007/s12070-025-05740-w","DOIUrl":"10.1007/s12070-025-05740-w","url":null,"abstract":"<p><p>Hansen's disease (leprosy) can have a myriad of presentations. The rheumatological presentation of leprosy has been described as the third most common presentation, following skin and nerve involvement. Aural involvement mimicking relapsing polychondritis (RPC) is rare in Hansen's disease. In this article, we describe a case series of patients of Hansens's disease presented with auricular perichondritis mimicking RPC. Although a clinical distinction can be made between the two, one should always support the diagnosis with tissue confirmation and avoid inappropriate immunosuppressive therapy.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"3312-3317"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case Report on Radiation-Induced Osteosarcoma of the Nasopharynx: Unmasking the Aftermath. 辐射诱发的鼻咽部骨肉瘤病例报告:揭露其后果。
IF 0.5
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-18 DOI: 10.1007/s12070-025-05533-1
Roshini Balu, Shrutikant Bhatia, Akash Dhiman, Sweety Gupta, Prashant Durgapal, Manoj Gupta
{"title":"Case Report on Radiation-Induced Osteosarcoma of the Nasopharynx: Unmasking the Aftermath.","authors":"Roshini Balu, Shrutikant Bhatia, Akash Dhiman, Sweety Gupta, Prashant Durgapal, Manoj Gupta","doi":"10.1007/s12070-025-05533-1","DOIUrl":"10.1007/s12070-025-05533-1","url":null,"abstract":"<p><p>Radiotherapy is commonly used in the curative treatment of head and neck cancers, serving both definitive and adjuvant roles. As oncologic outcomes improve, there is a rising occurrence of second malignancies among long-term survivors of these cancers. Radiation-induced osteosarcoma (RIOS) is an uncommon malignancy that emerges as a late consequence of radiotherapy. It usually develops within the irradiated area with a latency period of 5 to 20 years after treatment completion. However, cases of RIOS manifesting within a much shorter latency period, such as 2 years, are sporadic and highly atypical. This report presents a case of RIOS, highlighting the clinical course, diagnostic challenges, and management strategies of this aggressive secondary malignancy.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"3110-3114"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tissue Staplers in Transcervical Diverticulectomy - A Novel Approach to Closing Zenker's Diverticulum. 组织吻合器在经颈憩室切除术中的应用——一种闭合Zenker憩室的新方法。
IF 0.5
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-04 DOI: 10.1007/s12070-025-05598-y
Apoorva Kv, Pooja Varshini Raja, Vijendra Shenoy S, Ananya Sinha, Saksham Dhawan, Nayanika Reddy
{"title":"Tissue Staplers in Transcervical Diverticulectomy - A Novel Approach to Closing Zenker's Diverticulum.","authors":"Apoorva Kv, Pooja Varshini Raja, Vijendra Shenoy S, Ananya Sinha, Saksham Dhawan, Nayanika Reddy","doi":"10.1007/s12070-025-05598-y","DOIUrl":"10.1007/s12070-025-05598-y","url":null,"abstract":"<p><p>Zenker's diverticulum is a type of false pulsion diverticulum arising from the gap between the inferior constrictor muscle and the cricopharyngeus, secondary to heightened pressure within the lumen and a malfunctioning cricopharyngeal muscle. Surgery is the mainstay of treatment having exceptional success rates with the post-surgical risk of recurrence lying between 4.2 and 18.4%. The common surgical techniques being used at present are open diverticulectomy with cricopharyngeal myotomy, endoscopic CO2 laser diverticulotomy and endoscopic staple diverticulotomy [1] Here, we are presenting a novel surgical closure technique using tissue staplers for Zenker's diverticulum for a patient who underwent transcervical diverticulectomy which gave a satisfactory postoperative outcome, at par with the other surgical techniques that are currently being employed. A 72-year-old male who presented to us with complaints of regurgitation, dysphagia, chronic cough and foreign body sensation in the throat for the past 6 months was eventually diagnosed with pharyngeal diverticulum after radiological evaluation. Our fresh approach lies in its closure wherein the diverticulum was closed using tissue staplers, instead of the traditional sutures and excised with utmost hemostasis being secured. At his one-year follow-up, the patient had no complaints and was completely relieved of his previous symptoms.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"3164-3168"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Efficacy of Prostheses in Hearing Restoration: A Systematic Review and Network Meta-Analysis. 听力修复中假体的比较疗效:系统综述和网络荟萃分析。
IF 0.5
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-06 DOI: 10.1007/s12070-025-05605-2
Muhammad Asif Uddin Abbasi, Faheem Ahmed Khan, Aqeel Ur Rehman Hameed, Ayub Musani, Itrat Jawed, Mohsin Malik, S Umar Hasan
{"title":"Comparative Efficacy of Prostheses in Hearing Restoration: A Systematic Review and Network Meta-Analysis.","authors":"Muhammad Asif Uddin Abbasi, Faheem Ahmed Khan, Aqeel Ur Rehman Hameed, Ayub Musani, Itrat Jawed, Mohsin Malik, S Umar Hasan","doi":"10.1007/s12070-025-05605-2","DOIUrl":"10.1007/s12070-025-05605-2","url":null,"abstract":"<p><p>Chronic otitis media (COM) often leads to ossicular chain damage, necessitating ossiculoplasty for hearing restoration. Various prosthetic materials are available, including autologous grafts and synthetic materials like titanium, hydroxyapatite, and teflon. However, the comparative efficacy of these materials in ossiculoplasty remains unclear. This study aims to evaluate and compare the efficacy of different prosthetic materials used in ossiculoplasty. A systematic review and network meta-analysis were conducted, adhering to PRISMA guidelines. Studies comparing at least two different prosthetic materials in ossiculoplasty were included. Postoperative hearing outcomes were the primary focus measured at long-term follow-up (6-12 months). A Bayesian framework was used for the statistical analysis, incorporating both direct and indirect comparisons through a random-effects model. Seventeen studies with a total of 1,273 patients were included. Titanium and hydroxyapatite prostheses showed similar air-bone gap (ABG) outcomes, with mean effects of 16.00 dB but varying confidence intervals. Autologous and teflon showed the best air conduction (AC) outcomes with 31.00 and 32.00 dB respectively. In terms of bone conduction (BC) autologous and hydroxyapatite demonstrated similar results (18.00 dB). This network meta-analysis provides the first comprehensive comparison of prosthetic materials used in ossiculoplasty, demonstrating that autologous offers superior outcomes in AC and BC, while hydroxyapatite and titanium perform similarly in ABG closure. Despite these findings, no single prosthesis emerged as definitively superior across all outcomes, emphasizing the need for individualized prosthesis selection based on patient-specific factors. Further research with head-to-head trials and long-term follow-up is needed to optimize ossiculoplasty outcomes.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"3296-3307"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297193/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship Between Tinnitus and Hematological Parameters: A Case-Control Study. 耳鸣与血液学参数的关系:一项病例对照研究。
IF 0.5
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-05-23 DOI: 10.1007/s12070-025-05556-8
Serhan Keskin, Banu Atalay Erdoğan, Melis Demirag Evman, Ahmet Can Ciftci
{"title":"The Relationship Between Tinnitus and Hematological Parameters: A Case-Control Study.","authors":"Serhan Keskin, Banu Atalay Erdoğan, Melis Demirag Evman, Ahmet Can Ciftci","doi":"10.1007/s12070-025-05556-8","DOIUrl":"10.1007/s12070-025-05556-8","url":null,"abstract":"<p><p>Tinnitus, defined as the perception of sound without an external acoustic stimulus, has a multifactorial etiology, including metabolic, vascular, and neuro-otological factors. Microvascular dysfunction has been proposed as a possible mechanism in its pathogenesis. This study aimed to investigate whether changes in hematological parameters-specifically mean platelet volume (MPV), neutrophil/lymphocyte ratio (NLR), and platelet/lymphocyte ratio (PLR)-are associated with tinnitus. In this retrospective case-control study, 100 patients aged 18-59 with tinnitus and 100 age- and sex-matched healthy controls were included. Controls underwent hearing screening during the same period. Subjects with hearing loss, anatomical ear abnormalities, or systemic diseases were excluded. Hematological values including hemoglobin, neutrophil, lymphocyte, platelet counts, MPV, NLR, and PLR were recorded and compared between groups. Neutrophil and lymphocyte counts were significantly higher in the tinnitus group. However, both NLR and PLR values were significantly lower in these patients compared to controls (<i>p</i> < 0.05). The tinnitus group also had a significantly higher mean age and a greater proportion of female participants. Elevated neutrophil and lymphocyte levels may suggest an inflammatory or vascular role in tinnitus. However, the lower NLR and PLR findings complicate this interpretation, implying that other mechanisms may also be involved. Hematological markers such as NLR and PLR may contribute to understanding the underlying pathophysiology of tinnitus and warrant further investigation.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12070-025-05556-8.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"2812-2815"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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