Indian Journal of Otolaryngology and Head and Neck Surgery最新文献_第10页

Impact of Vitamin D3 Supplementation on Symptom Severity & IgE in Persistent Allergic Rhinitis. 补充维生素D3对持续性变应性鼻炎症状严重程度及IgE的影响。

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Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-05-01 Epub Date: 2025-04-11 DOI: 10.1007/s12070-025-05476-7

Amit Kumar Rana, Rohit Sharma, Mamta Verma, Abhay Deep Singh, Ashish Mehrotra

{"title":"Impact of Vitamin D3 Supplementation on Symptom Severity & IgE in Persistent Allergic Rhinitis.","authors":"Amit Kumar Rana, Rohit Sharma, Mamta Verma, Abhay Deep Singh, Ashish Mehrotra","doi":"10.1007/s12070-025-05476-7","DOIUrl":"https://doi.org/10.1007/s12070-025-05476-7","url":null,"abstract":"The potential for vitamin D₃ supplementation as adjunctive therapy in allergic rhinitis (AR) management remains a topic of considerable interest. Studies have investigated the relationship between serum vitamin D levels and AR severity, with conflicting results. To evaluate the impact of vitamin D₃ supplementation on symptom severity and IgE levels in patients with persistent allergic rhinitis (AR), and to assess the role of sustained supplementation in achieving long-term benefits. A randomized, double-blind, prospective interventional study was conducted at a teaching institute in India with 600 AR patients randomized into three groups: Group A (intranasal corticosteroids and placebo), Group B (intranasal corticosteroids and vitamin D₃ supplementation with maintenance doses), and Group C (intranasal corticosteroids and vitamin D₃ without maintenance doses). A control group of 200 healthy individuals was also included. Vitamin D₃, IgE levels, and Total Nasal Symptom Score (TNSS) were measured at baseline, 2 months, and 6 months. At baseline, 81.66% of AR patients had suboptimal vitamin D₃ levels compared to 65% in the control group. Group B showed the most significant improvement in vitamin D₃ levels, with 80% achieving normal levels by 6 months. TNSS and IgE levels also improved significantly in Group B, with sustained reductions compared to Groups A and C (p < 0.001). Group C showed a rebound in symptoms and IgE levels after discontinuation of supplementation. Sustained vitamin D₃ supplementation significantly improves symptom severity and IgE levels in patients with persistent AR. These findings suggest vitamin D₃ as a promising adjunct to standard AR treatment.","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 5","pages":"2123-2130"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spontaneous Orbital Emphysema: A Case Report. 自发性眼眶肺气肿1例。

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Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-05-01 Epub Date: 2025-04-08 DOI: 10.1007/s12070-025-05441-4

Hetal Marfatia, Anav Rattan, Ritika Dixit, Prateek Mohapatra

引用次数: 0

Effects of Orofacial Myofunctional Exercises on Uvulopalatopharyngoplasty Outcome: A Randomized Controlled Trial. 口面肌功能锻炼对腭咽成形术疗效的影响：一项随机对照试验。

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Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-05-01 Epub Date: 2025-04-22 DOI: 10.1007/s12070-025-05422-7

Reza Erfanian, Forough Mahdavian, Mostafa Rahimi, Saeid Sohrabpour, Reyhaneh Heydari, Maedeh Salehi, Mahdieh Sajedifar, Hamed Abdollahi

{"title":"Effects of Orofacial Myofunctional Exercises on Uvulopalatopharyngoplasty Outcome: A Randomized Controlled Trial.","authors":"Reza Erfanian, Forough Mahdavian, Mostafa Rahimi, Saeid Sohrabpour, Reyhaneh Heydari, Maedeh Salehi, Mahdieh Sajedifar, Hamed Abdollahi","doi":"10.1007/s12070-025-05422-7","DOIUrl":"https://doi.org/10.1007/s12070-025-05422-7","url":null,"abstract":"Obstructive sleep apnea (OSA) is a serious disorder that associated with repeated interruptions and resumptions of breathing during sleep, and is a major contributor to cardiovascular disease, hypertension and stroke in adult. One of the treatment methods for OSA is Uvulopalatopharyngoplasty (UPPP) which aimed to eliminate obstruction mainly at soft plate and oropharynx level to determine the effects of Orofacial Myofunctional Exercises (OME) on UPPP surgery. Forty patients who underwent UPPP were randomly allocated into two groups. The exercise group performed OME for 8 weeks. The control group performed no exercise. The apnea-hypopnea index (AHI), mean sleep saturation, time spent below 90% oxygen saturation (T90), lowest desaturation, Epworth Sleepiness Scale (ESS), and the Stanford Subjective Snoring Scale (SSSS) were measured in each group at the trial entrance time and 8 weeks later. No significant measurements' change was observed in the control group. In the exercise group significant improvements in AHI (P = 0.001), lowest desaturation (P = 0.02), T90 (P = 0.014) and ESS (P = 0.04) were observed but mean saturation and SSSS showed no significant change. At the end of study AHI in exercise group was significantly lower in the exercise group than control group (5.06 ± 5.36 vs. 10.15 ± 8.01, P = 0.02). OME over 8 weeks improved of the UPPP outcomes.","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 5","pages":"2020-2025"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nasal NK/T-Cell Lymphoma with Unusual Fonsecaea pedrosoi Infection: A Rare Case Report from Northeast India. 鼻NK/ t细胞淋巴瘤合并罕见的足癣菌感染：印度东北部一例罕见病例报告。

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Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-05-01 Epub Date: 2025-04-08 DOI: 10.1007/s12070-025-05455-y

Medozhanuo Solo, Neiluotuonuo Solo

引用次数: 0

Spontaneous Tumor Regression of Squamous Cell Carcinoma of Scalp, Case Report. 头皮鳞状细胞癌自发性肿瘤消退1例。

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Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-05-01 Epub Date: 2025-04-11 DOI: 10.1007/s12070-025-05411-w

Jessica Correa Marín, Juan José Vélez Rodriguez, Mónica Silva Martinez, Jorge Enrique Moreno Acuña

引用次数: 0

Effect of Hormonal Changes in Pre and Post-Menopausal Women Related Acoustical Voice Markers. 绝经前和绝经后妇女相关声音标记的激素变化的影响。

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Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-05-01 Epub Date: 2025-04-06 DOI: 10.1007/s12070-025-05437-0

Dinesh Bhatia, Koyel Das, Rubelsha Shabong, Tania Acharjee, Henry Benson Nongrum

{"title":"Effect of Hormonal Changes in Pre and Post-Menopausal Women Related Acoustical Voice Markers.","authors":"Dinesh Bhatia, Koyel Das, Rubelsha Shabong, Tania Acharjee, Henry Benson Nongrum","doi":"10.1007/s12070-025-05437-0","DOIUrl":"https://doi.org/10.1007/s12070-025-05437-0","url":null,"abstract":"Voice, in its most extensive definition, refers to the sound utilized for the transmission of thoughts, concepts, and opinions. This study investigates how vocal characteristics and function are affected by hormones during the process of aging and pregnancy. Through a systematic review of relevant literature during the period of 1965 to 2024, understanding the relationship between menopausal hormonal fluctuations and age-related vocal changes was carried out. The review identifies significant alterations in voice parameters linked to menopause, such as decreased fundamental frequency, increased vocal instability, and reduced voice quality in post- menopausal women compared to pre-menopausal women. Additionally, the analysis explores age-related vocal changes, noting gender differences. The results from the study show that the men generally experience a rise in speaking voice frequency with age, while women vocal trajectory is less clear. The findings emphasize the need for personalized interventions to address voice changes related to aging and hormonal shifts. By illuminating these complex vocal modulations across the lifespan, the review sets an underlying structure for the next studies aimed at optimizing voice care and improving the quality of life for those undergoing hormonal transitions and aging.","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 5","pages":"2038-2048"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enterprising a Central Sterile Supplies Department of an Otolaryngology & ENT Hospital. 某耳鼻喉科医院中心无菌用品部。

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Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-05-01 Epub Date: 2025-04-05 DOI: 10.1007/s12070-025-05431-6

Sonia S Daga, P Naveen Kumar

{"title":"Enterprising a Central Sterile Supplies Department of an Otolaryngology & ENT Hospital.","authors":"Sonia S Daga, P Naveen Kumar","doi":"10.1007/s12070-025-05431-6","DOIUrl":"https://doi.org/10.1007/s12070-025-05431-6","url":null,"abstract":"Background: Minimising the hospital acquired infections in a surgical specialty hospital is given highest preference among administrators of such hospitals. Standardization and centralization of all surgical supplies and instruments is of paramount importance to be done meticulously. The department which is responsible for processing, sterilizing and dispensing of all items of sterile equipment, sets and dressings to the rest of hospital is being referred as Central Sterile supplies department (CSSD) and managing it requires entrepreneurial skills.Objective: Many hospital administrators identify the inventory based on the clinicians' recommendations. This study gives a lucid account of instrument sets that are required in a 100 bed, 200 bed hospitals with given surgical specialties.Results: 36 and 49 types of instrument sets and 109 items of instruments in each tray would be required to 100 bed and 200 bed hospital respectively. About 174 and 236 is the ideal inventory of sets required. The sets are classified into big, medium and small sets for the convenience of sterilization in autoclaves. Each big set with its instruments would cost INR 40,170/-, medium set INR 12,280/- and small set INR 1194/- with 109, 21 and 4 instruments in each set.Conclusion: A hospital should have estimate of capital costs required to commission CSSD in buying each instrument set. Pilferage and condemnation of items can be minimized, if ideal inventory levels are maintained.","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 5","pages":"2032-2037"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of the Most Common Odours Recognizable in the South Indian Community. 鉴定在南印度社区可识别的最常见的气味。

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Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-05-01 Epub Date: 2025-04-22 DOI: 10.1007/s12070-025-05486-5

Unnikrishnan Menon, Suja Gopalakrishnan, Sadhana Rajnarayan, Nandini Lekha Rajesh, Neha Pramodan Korambra, L Saraswathy, C V Lalithambika, Harsha Hari

{"title":"Identification of the Most Common Odours Recognizable in the South Indian Community.","authors":"Unnikrishnan Menon, Suja Gopalakrishnan, Sadhana Rajnarayan, Nandini Lekha Rajesh, Neha Pramodan Korambra, L Saraswathy, C V Lalithambika, Harsha Hari","doi":"10.1007/s12070-025-05486-5","DOIUrl":"https://doi.org/10.1007/s12070-025-05486-5","url":null,"abstract":"The testing of the olfactory sense has gained importance after the onset of the COVID-19 pandemic. Internationally used kits such as the University of Pennsylvania Smell Identification Test (UPSIT) is not appropriate for all populations. From an Indian perspective, there is need for a simple, easily available, kit that can test the sense of smell in local populations; in the present case, the south Indian. With this aim, the objective of this study was to create a set of the most commonly recognized odorants in the accessible population of a cross-section of the community in Kochi, a metropolitan city in Kerala, south India. An initial list was created with the help of responses to a questionnaire disseminated amongst a random cross-section of people domiciled in south India. The result was a set of nearly 600 substances, from which the top 16 were selected, for a pilot. This was done to calculate sample size and assess the feasibility of the study in the community. Both the studies were published in the Kerala Sate ENT journal. 500 persons with no self-reported smell disorders were tested. Coffee, Camphor, Clove, Garlic, and Naphthalene were the top five odorants identified by the subjects. Some of these are peculiar to the place, in terms of familiarity and availability. This study highlights the difference in recognizability of odorants in a specific place. We hope to utilize the results for the creation of an actual olfactory kit for use by the medical community.","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 5","pages":"2131-2136"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12044095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comparative Study on Case-Based Learning and Interactive Lectures in Otorhinolayngology on Pre-final MBBS Students. 耳鼻喉学案例学习与互动讲座在MBBS学生期末前的比较研究。

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Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-05-01 Epub Date: 2025-04-15 DOI: 10.1007/s12070-025-05440-5

Aditya Gargava, Praveen Singh, Tina Rai, Vaishali Jain, Shiv Kumar Raghuwanshi

{"title":"A Comparative Study on Case-Based Learning and Interactive Lectures in Otorhinolayngology on Pre-final MBBS Students.","authors":"Aditya Gargava, Praveen Singh, Tina Rai, Vaishali Jain, Shiv Kumar Raghuwanshi","doi":"10.1007/s12070-025-05440-5","DOIUrl":"https://doi.org/10.1007/s12070-025-05440-5","url":null,"abstract":"This study evaluates the impact of case-based learning (CBL) on undergraduate medical students' learning in ENT and compares its effectiveness to didactic lectures, alongside assessing perceptions from students and faculty.The primary goals are to assess learning outcomes from CBL versus didactic lectures and gather perceptions on these teaching methods. Conducted over five months with 100 pre-final year MBBS students at Govt Medical College, Vidisha, the study involved a prospective educational intervention design. Students alternated between CBL and didactic lectures for two topics, with knowledge assessed through pre- and post-tests and perceptions collected via surveys. Results Initial knowledge scores were comparable (p > 0.05). Post-intervention, both groups showed significant improvements (p < 0.05), with the CBL group outperforming the didactic group (p < 0.05). Notably, 98% of students felt CBL enhanced retention, and 96% believed it improved understanding and problem-solving. Faculty favored CBL as a more effective teaching method. CBL promotes deeper learning and self-directed study in medical education. The favorable feedback from students and faculty supports integrating CBL with traditional lectures to enhance educational outcomes.","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 5","pages":"2049-2054"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12044094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breaking New Ground: Novel Intralesional Amphotericin B for Mucormycosis. 突破性进展：用于毛霉病的新型局部两性霉素B。

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Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-05-01 Epub Date: 2025-04-23 DOI: 10.1007/s12070-025-05479-4

Nidhin Das K, Vidhu Sharma, Kapil Soni, Amit Goyal

{"title":"Breaking New Ground: Novel Intralesional Amphotericin B for Mucormycosis.","authors":"Nidhin Das K, Vidhu Sharma, Kapil Soni, Amit Goyal","doi":"10.1007/s12070-025-05479-4","DOIUrl":"https://doi.org/10.1007/s12070-025-05479-4","url":null,"abstract":"Mucormycosis, a severe fungal infection with high morbidity and mortality rates, particularly affects immunocompromised individuals. Standard treatments involving debridement and systemic antifungals often encounter resistance, especially in cutaneous forms due to systemic toxicity and poor tissue penetration of Amphotericin B. This case series investigates the effectiveness of intralesional Amphotericin B for targeted delivery with minimal systemic side effects. Three cases are presented: a 50-year-old man with invasive mucormycosis in the sinuses and frontal bone, a 10-year-old boy with poorly controlled diabetes and periorbital mucormycosis, and a 62-year-old man with diabetes and periorbital cellulitis from invasive fungal sinusitis. All underwent surgical debridement followed by systemic and intralesional Amphotericin B. The intralesional treatment, administered over seven consecutive days, resulted in significant clinical and radiological improvements, with complete resolution of cutaneous involvement. This series marks the first documentation of intralesional Amphotericin B's efficacy in mucormycosis, suggesting it as a promising alternative for refractory cases. Previous studies on cutaneous leishmaniasis also support its potential, showing high recovery rates with minimal side effects. Further research is needed to confirm these findings and optimize treatment protocols.","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 5","pages":"2183-2187"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12044091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0