{"title":"Non Functioning Vagal Paraganglioma in the Infrahyoid Neck: A Case Report.","authors":"Arsheed Hussain Hakeem, Novfa Iftikhar, Tejal Modi","doi":"10.1007/s12070-024-05293-4","DOIUrl":"10.1007/s12070-024-05293-4","url":null,"abstract":"<p><p>Paragangliomas are rare mostly benign, highly vascular tumors that derive from paraganglionic tissue of neural crest origin. Vagal paragangliomas account for only 3% of all head and neck paragangliomas. Most of the paragangliomas are seen in the rostral portion of the vagus nerve in the vicinity of the ganglion nodosum. Patients with vagal paragangliomas typically present with an asymptomatic neck mass and, less frequently, with cranial neuropathies. Most of the head and neck paragngliomas are non secretory as only 1-3% of all head and neck paragangliomas secrete catecholamines. MRI scans are more useful than the CT scan due to better soft tissue contrast delineation. The mainstay treatment is surgical removal. We report a patient with non -functioning vagal paraganglioma located in the infra-hyoid carotid sheath. The findings of diagnostic imaging workup like ultrasonography, computed tomography, and magnetic resonance, were suggestive of paraganglioma. The tumor could not be separated from the vagus nerve and was resected along with the nerve segment. Head and neck surgeons should be aware of the rare presentation of the vagal paraganglioma in the lower neck apart from the usual rostral position.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 2","pages":"1115-1119"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quality of Life and Nutritional Outcomes with PEG Feeding in Locally Advanced Oral Cancer: An Institutional Experience.","authors":"Surjeet Dwivedi, Sanjay Kumar, Surendra Kumar, Angshuman Dutta, Sabita Dwivedi, Lakshmi Geeta Nair","doi":"10.1007/s12070-024-05313-3","DOIUrl":"10.1007/s12070-024-05313-3","url":null,"abstract":"<p><p>Locally advanced oral carcinoma requires extensive surgical intervention, leading to significant postoperative nutritional challenges. Percutaneous Endoscopic Gastrostomy (PEG) feeding has emerged as a preferred method over nasogastric (NG) feeding, providing consistent nutritional support that aids recovery by reducing complications and enhancing quality of life. This prospective cohort study followed 50 patients with locally advanced oral carcinoma requiring postoperative PEG feeding. Patients were assessed over a 6-month period for nutritional status (BMI, serum albumin), inflammatory markers (CRP, ESR), quality of life (EORTC QLQ-C30), and psychosocial well-being (HADS). Complication rates and patient satisfaction were also recorded. After 6 months, mean BMI increased from 18.5 ± 2.5 kg/m² to 19.0 ± 2.7 kg/m², while serum albumin rose from 2.8 ± 0.5 g/dL to 3.4 ± 0.5 g/dL, indicating nutritional recovery. CRP and ESR levels declined from 25 ± 5 mg/L to 15 ± 3 mg/L and 30 ± 7 mm/hr to 22 ± 5 mm/hr, respectively, reflecting reduced inflammation. Quality of life scores improved, with global health rising from 50 ± 10 to 70 ± 15, and anxiety and depression scores decreasing from 12 ± 4 and 14 ± 4 to 8 ± 3 and 9 ± 3. The complication rate was low (30%), and patient satisfaction increased from 7.5 ± 1.2 to 8.5 ± 1.1. PEG feeding significantly improves nutritional recovery, reduces inflammation, and enhances quality of life in postoperative oral carcinoma patients, supporting its role as a standard of care.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12070-024-05313-3.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 2","pages":"952-959"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Understanding the Vestibular Apparatus: How 3D Models Can Improve Student Learning.","authors":"Amanda Ragland, Lauren Linquest, Runhua Shi, Gauri Mankekar","doi":"10.1007/s12070-024-05272-9","DOIUrl":"10.1007/s12070-024-05272-9","url":null,"abstract":"<p><p>The objective of this study is to compare student satisfaction and confidence following a presentation of the inner ear anatomy using either a 2D model or a 3D model. First-year medical students were randomized to a 2D or 3D teaching group and given a presentation on the inner ear. Students were surveyed on confidence levels pre- and post-presentation, helpfulness of the presentation, and completed the student satisfaction and self confidence in learning (SCLS) questionnaire. 30 first-year medical students participated in the study: 14 in the 2D model and 16 in the 3D model group. A statistical significance was found between the 2D and 3D group regarding the helpfulness of the model (<i>p</i> = 0.0147), Q1 of the SCLS questionnaire (<i>p</i> = 0.0365), and Q12 of the SCLS questionnaire (<i>p</i> = 0.0308). The use of a 3D model of the inner ear aids in student self-confidence regarding the material and is perceived to be helpful with learning the material.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 2","pages":"854-862"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Congenital Cheek Salivary Fistula Associated with an Aberrant Parotid Duct System: Embryological Considerations and Surgical Repair.","authors":"Kamana Jyotsna Devi, Kalaiarasi Raja, Subathra Adithan, Sabharisan Paramasivam","doi":"10.1007/s12070-024-05306-2","DOIUrl":"10.1007/s12070-024-05306-2","url":null,"abstract":"<p><p>Congenital cheek salivary fistula is a rare developmental anomaly with an abnormal connection between the parotid gland and the skin. An eight-year-old child presented with an opening on the right cheek, with intermittent saliva leakage aggravated during food intake and recurrent infections. Imaging studies had confirmed the diagnosis. Surgical excision of the fistulous tract successfully alleviated the patient's symptoms.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 2","pages":"1129-1132"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Rare Case of Unilateral Congenital Asymmetric Crying Facies in a Neonate: Case Report.","authors":"Gautam Kumar Arora, Pankaj Kumar Doloi","doi":"10.1007/s12070-024-05230-5","DOIUrl":"10.1007/s12070-024-05230-5","url":null,"abstract":"<p><p>Asymmetric crying facies (ACF) due to Congenital hypoplasia of the depressor anguli oris muscle (CHDAOM) is a rare congenital condition that affects the development of a specific facial muscle responsible for depressing the corner of the mouth. CHDAOM has an unknown aetiology but is associated with other genetic syndromes like DiGeorge syndrome and Cayler cardiofacial syndrome. We report a distinct case of a newborn with unilateral asymmetric crying facies at our hospital, and clinical features, examination, and management of the above condition.The overarching goal is to enhance awareness, understanding, and management of CHDAOM, ultimately improving the lives of those affected by it.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12070-024-05230-5.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 2","pages":"1003-1006"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incidental Thyroid Goiter with Large Posterior Mediastinal Extension: A Case Report.","authors":"Mitanshi Manish Luhana, Aditya Jain","doi":"10.1007/s12070-024-05157-x","DOIUrl":"10.1007/s12070-024-05157-x","url":null,"abstract":"<p><p>Mediastinal goiters represent descent of thyroid tissue from the neck to the intra thoracic cavity most commonly in the anterior mediastinal compartment. Posterior mediastinal extension is uncommon, comprising only 10-15% of all mediastinal goiters. Thyroid masses within mediastinum may present with range of symptoms from being asymptomatic to severe compressive symptoms according to size and location. Surgical excision is treatment of choice in most cases. Although cervical approach is sufficient for most anterior mediastinal goiters, additional extra cervical approaches may be required for posterior mediastinal goiters. We report a case of 48-year-old female patient with an incidental finding of a thyroid goiter having large extension in right posterior mediastinum found on CT scan. It was excised using combination of cervical and Video Assisted Thoracoscopic Surgery and posterolateral thoracotomy approach with uneventful post-operative period. Histopathology revealed it to be benign multinodular goiter.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 2","pages":"1059-1061"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management of a Huge Arteriovenous Malformation of the Tongue with the Submandibular Gland Flap: A Case Report.","authors":"Bhushan Kathuria, Vikas Kakkar, Surya Udai Singh, Saral Ahuja","doi":"10.1007/s12070-024-05205-6","DOIUrl":"10.1007/s12070-024-05205-6","url":null,"abstract":"<p><p>AVMs commonly manifest in childhood or adolescence, and can occur at any area of the body. The management could be conservative or surgical. Surgical excision of a tongue AVM requires adequate reconstruction and Submandibular gland proves to be an excellent modality for the same. We present a case of an enormous AVM over the tongue, it's surgical management, and reconstruction with the Submandibular Gland.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 2","pages":"990-992"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Microscopic Coblator Assisted Excision of Adenocystic Carcinoma of Soft Palate: A Novel Modality.","authors":"Abhik Sikdar, Priyanka Singh, Sameer Nivsarkar, Shrikant Phatak, Richa Agarwal, Ankit Mangal, Priyanka Bhagat, Nitika Yadav","doi":"10.1007/s12070-024-05203-8","DOIUrl":"10.1007/s12070-024-05203-8","url":null,"abstract":"<p><p>Adenoid cystic carcinoma (ACC) is a rare malignancy arising from the exocrine glands. It most commonly involves the minor salivary glands. In the oral cavity, palate is the commonest site. For palatal ACC, surgical resection is the primary treatment of choice. However the tumour location makes complete resection demanding, due to its associated complications of velopharyngeal insufficiency, oronasal fistula, foreign body sensation and pain. Various techniques like coblation, CO<sub>2</sub> laser and robotic surgery are available for the trans-oral resection of oral and oropharyngeal tumours. Recently, the use of coblator in the treatment of oropharyngeal malignancy has generated a considerable interest. Coblation is a suitable tool for resection of oral and oropharyngeal tumours with a favourable intraoperative performance and less post-operative morbidity. It allows working around the corners, is faster, cheaper and has the ability to achieve better haemostasis in comparison to other surgical modalities. Herein, we present an elderly lady with a palatal tumour which was benign on clinical examination and encapsulated with maintained fat planes on radiological evaluation. She underwent coblator assisted resection under microscopic vision which allowed quick excision with adequate margins under magnified vision. There were minimal post-operative complications. Histopathology documented the lesion as ACC with free surgical margins. It should be kept in mind that palatal mass even if clinically and radiologically benign may harbour malignancy. Use of coblator under microscopic vision allows delineation between tumour and different layers of palatal muscles which helps in more accurate and individualised resection and reduced postoperative morbidity.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 2","pages":"652-658"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rogerio Pezato, Gurpreet K Singhera, Tony Ju Feng Guo, Delbert R Dorscheid, Athenea Pascual, Andrew Thamboo
{"title":"Nasal irrigation solution is less cytotoxic to nasal epithelial cells than nasal spray.","authors":"Rogerio Pezato, Gurpreet K Singhera, Tony Ju Feng Guo, Delbert R Dorscheid, Athenea Pascual, Andrew Thamboo","doi":"10.1007/s12070-024-05291-6","DOIUrl":"10.1007/s12070-024-05291-6","url":null,"abstract":"<p><strong>Background: </strong>Recent studies have demonstrated that corticosteroid delivered by nasal irrigation is superior to nasal spray in the treatment of chronic rhinosinusitis patients who have undergone sinus surgery. However, the local cytotoxicity of both delivery methods has not been previously evaluated. In this study we aimed to evaluate the cytotoxicity of corticosteroid prepared nasal irrigation solution and commercially available corticosteroid nasal spray.</p><p><strong>Methods: </strong>Primary human nasal epithelial air-liquid interface 3D cultures established from nasal brushes from patients with nasal diseases with polyps, and healthy nasal mucosa (<i>n</i> = 6 each) were used to assess the cytotoxicity of different drug concentrations. The following drugs were screened: budesonide rinse, mometasone rinse, mometasone spray, fluticasone spray, azelastine/fluticasone spray, xylometazoline drops and benzalkonium chloride. Nasal epithelial cell characterization at passage zero was evaluated with β- Tubulin and FOXJ1 immunostaining as well as fluorescence-activated cell sorting using epithelial cell marker (EpCAM-488). To assess the drug induced cytotoxicity, an Alamar Blue assay, transepithelial electrical resistance and optical microscopy were applied.</p><p><strong>Results: </strong>Nasal irrigation using standard therapeutic concentrations of mometasone or budesonide demonstrated less cytotoxicity when compared to nasal spray of mometasone and fluticasone in stock concentration prescribed by the manufacturer. Nasal spray diluted by a factor of 10 demonstrated similar cytotoxicity to nasal irrigation using therapeutic concentration. This study reinforces the suspicion that it is not the drugs themselves but benzalkonium chloride that is the most involved in cytotoxicity.</p><p><strong>Conclusion: </strong>Corticosteroid irrigation is less cytotoxic than corticosteroid spray to nasal epithelial cells.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 2","pages":"905-912"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nongthombam Surjalata Devi, Amit Kumar, Vetrivel G, Rachit Sood, Amit Kumar Tyagi, Bhinyaram Jat, Sourabha Patro, Praveen A Jayaprakash, Ramesh Prasath, Akhilesh Chandra Yadav, R Nivedhan
{"title":"Assessment of Quality-of-Life Measurement Instruments for Chronic Otitis Media: A Systematic Review Using the COnsensus-Based Standards for the Selection of Health Measurement Instruments (COSMIN) Checklist.","authors":"Nongthombam Surjalata Devi, Amit Kumar, Vetrivel G, Rachit Sood, Amit Kumar Tyagi, Bhinyaram Jat, Sourabha Patro, Praveen A Jayaprakash, Ramesh Prasath, Akhilesh Chandra Yadav, R Nivedhan","doi":"10.1007/s12070-024-05224-3","DOIUrl":"10.1007/s12070-024-05224-3","url":null,"abstract":"<p><p>The purpose of our study is to assess the psychometric measurement properties of various questionnaires for quality of life in adult patients with chronic otitis media (COM) using the preferred reporting items for systematic reviews and meta-analysis protocol and the COnsensus based Standard for the selection of health Measurement Instruments (COSMIN) checklist. A thorough electronic search was performed with a date limitation of 23rd September 2021 using the following five electronic databases: OVID, Embase, Cochrane Library, PubMed, and Scopus. Only full-text articles in the English language about the development or validation of a self-administered measurement instrument to assess QOL in COM patients (≥ 18 years) that assesses one or more of the measurement properties developed by the COSMIN guidelines were included in the study. Five studies were found evaluating four self-administered questionnaires: the Zurich Chronic Middle Ear Inventory-21 (ZCMEI- 21-E), the Chronic Otitis Media Benefit Inventory (COMBI), the chronic otitis media questionnaire-12 (COMQ-12) and the chronic ear survey in COM patients. Most of the PROMs included in our review did not meet the proposed criteria and need further validation. The ZCMEI-21-E performed better than other available PROMs based on the present review. The present study clarified the quality of currently available HRQoL instruments for COM. Using the COSMIN guidelines, it was shown that there are areas for improvement in study designs evaluating many of the PROMs currently being used in the COM. PROMs should follow COSMIN guidelines to adequately assess the Health-Related Quality of Life of patients suffering from various illnesses.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12070-024-05224-3.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 2","pages":"699-710"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11890822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}