Interventional Neuroradiology最新文献

{"title":"Distal vessel aspiration in acute ischaemic stroke using the RED 43 aspiration catheter (DIVA study): An international multicentre experience.","authors":"Vinicius Carraro do Nascimento, Permesh Singh Dhillon, Laetitia de Villiers, Strahan Teoh, Timothy Phillips, David Brennan, Waleed Butt, Mohammad Al-Tibi, Daniela Mantovani Anoni, Luqman Malik, Hal Rice","doi":"10.1177/15910199251346007","DOIUrl":"10.1177/15910199251346007","url":null,"abstract":"<p><p>BackgroundFor medium vessel occlusions (MeVOs), in acute ischaemic stroke (AIS), the clinical efficacy of mechanical thrombectomy (MT) is the topic of ongoing randomised clinical trials, and the optimal recanalisation technique remains undetermined. We aim to assess the effectiveness and safety of the novel RED 43 distal reperfusion catheter for the treatment of MeVOs.MethodsWe retrospectively reviewed consecutive cases of anterior and posterior circulation MT for MeVO where the RED 43 aspiration catheter was used at four comprehensive stroke centres in Australia and United Kingdom, from April 2023 to June 2024. Procedural outcomes (navigation to the target vessel, final near complete-complete recanalisation (extended Thrombolysis in Cerebral Infarction (eTICI) 2c-3) and single-pass eTICI 2c-3 (first-pass effect (FPE)), 90-day modified Rankin score, safety and procedural complications (haemorrhagic, vessel dissection or perforation) were analysed.ResultsSeventy-four patients were included (median age 72.8 years [SD 13.1]; 33.8% females). Median baseline NIHSS was 10 [iQR 5-15], and median ASPECTS was 9. Primary MeVOs (without large vessel occlusion) accounted for 58.1% of cases. The occlusion site was reached using the RED 43 in 100% of cases. In particular, the target was reached navigating the catheter over a microwire only in 83.8% of cases. Fifty-seven (77%) patients achieved final eTICI 2c-3 and the FPE (eTICI 2c-3) for the RED 43 was 60.8%. Modified Rankin Scale (mRS) ≤ 2 at 90-days was 67.1%. No intraprocedural complications were recorded. Symptomatic intracranial haemorrhage and 90-day mortality rates were 4.1% and 19%, respectively.ConclusionThe novel RED 43 distal aspiration catheter was shown to be safe and effective in achieving good technical and clinical outcomes amongst acute stroke patients presenting with MeVO. If MT for MeVO is proven to be efficacious, future studies should aim to compare available MT techniques in achieving fast and complete vessel recanalisation.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2811-2817"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and radiographic outcomes after mechanical thrombectomy in medium-vessel posterior cerebral artery occlusions: Subgroup analysis from STAR.","authors":"Eyad Almallouhi, Matthew C Findlay, Ilko Maier, Pascal Jabbour, Joon-Tae Kim, Stacey Quintero Wolfe, Ansaar Rai, Robert M Starke, Marios-Nikos Psychogios, Amir Shaban, Nitin Goyal, Shinichi Yoshimura, Hugo Cuellar, Brian Howard, Ali Alawieh, Ali Alaraj, Mohamad Ezzeldin, Daniele G Romano, Omar Tanweer, Justin Mascitelli, Isabel Fragata, Adam Polifka, Fazeel Siddiqui, Joshua Osbun, Roberto Crosa, Charles Matouk, Min S Park, Michael R Levitt, Waleed Brinjikji, Mark Moss, Ergun Daglioglu, Richard Williamson, Pedro Navia, Peter Kan, Reade De Leacy, Shakeel Chowdhry, David J Altschul, Alejandro Spiotta, Ramesh Grandhi","doi":"10.1177/15910199241273839","DOIUrl":"10.1177/15910199241273839","url":null,"abstract":"<p><p>BackgroundWhereas mechanical thrombectomy (MT) has become standard-of-care treatment for patients with salvageable brain tissue after acute stroke caused by large-vessel occlusions, the results of MT in patients with medium-vessel occlusions (MEVOs), particularly in the posterior cerebral artery (PCA), are not well known.MethodsUsing data from the international Stroke Thrombectomy and Aneurysm Registry (STAR), we assessed presenting characteristics and clinical outcomes for patients who underwent MT for primary occlusions in the P2 PCA segment. As a subanalysis, we compared the PCA MeVO outcomes with STAR's anterior circulation MeVO outcomes, namely middle cerebral artery (MCA) M2 and M3 segments.ResultsOf the 9812 patients in STAR, 43 underwent MT for isolated PCA MeVOs. The patients' median age was 69 years (interquartile range 61-79), and 48.8% were female. The median NIH Stroke Scale score was 9 (range 6-17). After recanalization, 67.4% of patients achieved successful recanalization (modified treatment in cerebral infarction score [mTICI] ≥ 2b), with a first-pass success rate of 44.2%, and 39.6% achieved a modified Rankin score of 0-2 at 90 days. Nine patients (20.9%) had died by the 90-day follow-up. In comparison with M2 and M3 MeVOs, there were no differences in presenting characteristics among the three groups. Patients with PCA MeVOs were less likely to undergo intra-arterial thrombolysis (4.7% PCA vs. 10.1% M2 vs. 16.2% M3, p = 0.046) or to achieve successful recanalization (mTICI ≥ 2b, 67.4%, 86.7%, 82.3%, respectively, p < 0.001); however, there were no differences in the rates of successful first-pass recanalization (44.2%, 49.8%, 52.3%, respectively, p = 0.65).ConclusionsWe describe the STAR experience performing MT in patients with PCA MeVOs. Our analysis supports that successful first-pass recanalization can be achieved in PCA MEVOs at a rate similar to that in MCA MeVOs, although further study and possible innovation may be necessary to improve successful PCA MeVO recanalization rates.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2227-2233"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569802/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stent retriever expansion as a corrective maneuver to optimize inadequately deployed flow diverter stents.","authors":"A Khanafer, M Almohammad, P von Gottberg, K Hajiyev, A Kemmling, M Forsting, H Henkes","doi":"10.1177/15910199241302436","DOIUrl":"10.1177/15910199241302436","url":null,"abstract":"<p><p>Background and PurposeAs flow diversion (FD) is becoming increasingly important in the endovascular treatment of intracranial aneurysms, the rate of technical complications is also increasing. Inadequate FD implantation may lead to both ischemic complications and decreased treatment efficacy. The aim of this study was to evaluate the efficacy of off-label stent retriever (SR) use in managing technical complications associated with FD implantation.Materials and MethodsA retrospective analysis of data from patients who underwent FD treatment at two neuroradiology centers was performed. The objective was to identify cases in which the FD was inadequately deployed and SR expansion was performed as a corrective maneuver. The analysis included anatomic characteristics, technical information, angiographic and clinical outcomes, and complications.ResultsA total of 35 corrective maneuvers with SR were performed in 25 FD treatments. The corrective maneuvers in all treatments were successful, and no additional devices or therapies were required. No procedural complications or technical difficulties were documented.ConclusionWith the growing role of FDs in neurointerventional treatment, familiarity with corrective maneuvers after technical complications or inadequate implantation is important. The findings in our selected cohort demonstrated that SR expansion is an effective and safe corrective maneuver for incompletely opened FDs.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2572-2579"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spinal arteriovenous fistula leading to acute paraplegia after a lumbar nerve root block: Successful embolization with complete neurological recovery-a case report.","authors":"Diego Gonzalez-Morgado, Marta de Dios-Lascuevas, Ferran Blasco-Casado, Xurxo Segura-Navarro, Alejandro Tomasello-Weitz, Carlos Piñana, Sleiman Haddad","doi":"10.1177/15910199241276578","DOIUrl":"10.1177/15910199241276578","url":null,"abstract":"<p><p>Spinal arteriovenous fistulas (SAVFs) are the most common type of vascular malformation of the spine in adult patients. They can lead to acute or progressive myelopathy due to venous congestion of the medullary veins. While most SAVFs are acquired, their pathophysiology remains unclear. The natural history of the disease and its clinical presentation are highly influenced by the location of the fistula and various factors may trigger sudden neurological decline. We present a case of a patient who developed a complete spinal cord injury after a lumbar nerve root block, likely due to an undiagnosed SAVF. The patient underwent endovascular embolization, resulting in a complete recovery of neurological function.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2853-2857"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Next-generation Onyx DES for elective intracranial atherosclerosis: A meta-analysis.","authors":"Toka Adel Hassan, Ahar Bhatt, Fadar Oliver Otite, Steven Hoover, Danish Kherani, Maia Killory, Kaustubh Limaye, Tapan Mehta, Ameer E Hassan, Smit D Patel","doi":"10.1177/15910199251361312","DOIUrl":"10.1177/15910199251361312","url":null,"abstract":"<p><p>BackgroundIntracranial atherosclerotic disease (ICAD) is a growing cause of ischemic stroke globally, with a disproportionately high burden in Asian, Black, and Hispanic populations. Despite advances in medical therapy, ICAD remains associated with high rates of recurrent stroke, prompting interest in durable endovascular solutions. This study aims to systematically evaluate the current evidence on the safety and efficacy of elective intracranial stenting in adult patients with symptomatic ICAD using Onyx drug-eluting balloon-mounted stents (Onyx DES).MethodsA meta-analysis was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Five studies were initially identified, with one excluded due to overlapping cohorts, resulting in four final studies included for analysis. Meta-analysis was conducted utilizing random-effects models for pooled event rates (95% CIs) and weighted means.ResultsOf 153 articles initially identified, four high-quality studies encompassing 314 patients met inclusion criteria. The mean (±SD) age was 64.6 (±12.4) years, with a predominance of males (70.7%) and common vascular comorbidities such as hypertension (85.7%) and diabetes (60.0%). Lesions were nearly equally distributed between the anterior and posterior circulations. Periprocedural complications were infrequent (1.0%), including one hemorrhagic stroke and one fatal aneurysm rupture. The 30-day complication rate remained low at 5%, involving strokes, deaths, and TIAs. However, follow-up at six months and beyond revealed rising rates of strokes, TIAs, and in-stent restenosis, reaching 9% at six months and persisting through one year.ConclusionThis descriptive meta-analysis suggests that Onyx DES may offer promising results in the treatment of symptomatic ICAD, with lower early complication rates reported. However, larger prospective studies are needed to confirm these observations and evaluate long-term efficacy and safety.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2755-2763"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric interventional neuroradiology: \"How I do it\" vol. II-Embolization.","authors":"Jesse George Atherton Jones, John Deveikis","doi":"10.1177/15910199241275710","DOIUrl":"10.1177/15910199241275710","url":null,"abstract":"<p><p>Pediatric arteriovenous shunts can be challenging to embolize and the consequences of excess venous penetration disastrous. Moreover, the congenital nature of most shunts necessitates neonatal intervention whenever (medically refractory) heart failure occurs. Here, we describe current endovascular treatment strategies based on personal experience and literature review. While disparate, arteriovenous malformation, dural arteriovenous fistula (AVF), pial AVF, and vein of Galen aneurysmal malformation share unifying features such as high output heart failure and venous hypertension. This tutorial is divided into passages on Goals, Access, and Treatment which respect differences among pediatric arteriovenous shunts while maintaining a narrative economy.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2252-2257"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The middle meningeal artery Patency After Coil Embolization (PACE) score: A novel descriptor of angiographic occlusion.","authors":"Nicholas S Hernandez, Ryan W Sindewald, Michael G Brandel, Arvin R Wali, Nikhil K Murthy, Jeffrey A Steinberg, Jeffrey S Pannell, Alexander A Khalessi, David R Santiago-Dieppa","doi":"10.1177/15910199241308324","DOIUrl":"10.1177/15910199241308324","url":null,"abstract":"<p><p>IntroductionA scoring system to characterize the efficacy of middle meningeal artery (MMA) embolization is lacking and would help predict the likelihood of subdural hematoma resolution.MethodsWe developed a simple angiographic classification system ranging from 0 to 3 for quantifying MMA Patency After Coil Embolization (PACE) based residual flow distal to the embolization. MMA embolizations using coils at our institution were used to validate the PACE score system using procedural angiograms. Follow-up CT scans following embolization were reviewed for acute blood products, and to characterize long-term resolution.Results60 patients were included in the study, with a total of 80 subdural hematomas with follow-up imaging that were available for analysis. 37 patients had a PACE score of 0, 18 had a PACE score of 1, 4 had a PACE score of 2, and 1 had a PACE score of 3. The presence of acute blood products was significantly lower in PACE 0 compared to PACE 1, 2, or 3. The cross-sectional area of the chronic subdural collections was statistically lower on follow-up CT scans after coil embolization.ConclusionsCoil embolization of the MMA may reduce the incidence of acute blood products after embolization and decrease the cross-sectional area of chronic subdural hematoma on long-term follow-up. Lower PACE scores may correlate with lower rates of acute blood products after the procedure and increased resolution of chronic subdural hematoma on follow-up. A larger cohort is required to characterize the superiority between the PACE scores.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2610-2616"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11669128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DWI lesions after intracranial aneurysm treatment with contour or WEB-does the device matter?","authors":"Friederike Gärtner, Tristan Klintz, Sönke Peters, Justus Mahnke, Karim Mostafa, Fernando Bueno Neves, Johannes Hensler, Naomi Larsen, Olav Jansen, Fritz Wodarg","doi":"10.1177/15910199241290844","DOIUrl":"10.1177/15910199241290844","url":null,"abstract":"<p><p>ObjectiveIn this study, we report our experience with the occurrence of diffusion-weighted imaging (DWI) lesions following aneurysm treatment with Woven EndoBridge (WEB) device and Contour Neurovascular System in elective settings. We compared both techniques in a retrospective single-center analysis, to investigate whether there are significant differences in the incidence of microemboli depending on the device used.Materials and methodsSixty-two cases treated with Contour were retrospectively compared with 84 WEB cases. Postinterventional MRI was performed in all patients within five days after the angiographic procedure. Only DWI lesions in the dependent vascular territory of the treated aneurysm were considered. Data on occurrence of DWI lesions, device implantation times as well as device change or repositions maneuvers were compared.ResultsA total of 146 patients were included in this study. Postinterventional DWI lesions were detected in 33 of the 62 (53.2%) Contour cases and in 36 of the 84 (42.8%) WEB cases with an average lesion number of 1.70 ± 3.45 in our WEB group and 1.68 ± 2.53 in our Contour cohort. Neither periinterventional device changes nor device reposition maneuvers had a significant impact on the occurrence of DWI lesions. Although four patients experienced transient neurological deterioration, the DWI lesions were not clinically relevant at the time of discharge, as the patients' NIHSS remained stable compared to the preintervention NIHSS in the entire cohort. There was no statistically significant difference between the implantation times of WEB and Contour, although Contour could be implanted slightly faster.ConclusionAneurysm treatment with WEB or Contour results in a comparable numbers of procedure-related DWI lesions. This effect was consistent after adjustment for other demographic or technical variables.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2515-2520"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559872/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Basilar artery occlusion management: An international survey of gender influence on management.","authors":"Meabh Peacock, Brian Drumm, Piers Klein, Jean Raymond, Xiaochuan Huo, Yimin Chen, Mohamad Abdalkader, Wouter J Schonewille, Xinfeng Liu, Wei Hu, Chuanhui Li, Xunming Ji, Fana Alemseged, Liping Liu, James E Siegler, Simon Nagel, Daniel Strbian, Simona Sacco, Shadi Yaghi, Muhammad M Qureshi, Urs Fischer, Diana Aguiar de Sousa, Hiroshi Yamagami, Patrik Michel, Volker Puetz, Adnan Mujanovic, João Pedro Marto, Espen Saxhaug Kristoffersen, Else C Sandset, Jelle Demeestere, Uta Hanning, Robin Novakovic, Cynthia Kenmuir, Ronit Agid, Michele Romoli, Francesco Diana, Kyriakos Lobotesis, Dylan Roi, Hesham E Masoud, Alice Ma, Yuyou Zhu, Hongfei Sang, Dapeng Sun, Mai Duy Ton, Raynald, Fengli Li, Ahmed Nasreldein, Jessica Jesser, Johannes Kaesmacher, Charlotte S Weyland, Lukas Meyer, Leonard L L Yeo, Qingwu Yang, Götz Thomalla, Pengfei Yang, Sven Poli, Bruce C V Campbell, Adnan I Qureshi, Hui-Sheng Chen, Osama O Zaidat, Zhongming Qiu, Raul G Nogueira, Tudor G Jovin, Zhongrong Miao, Thanh N Nguyen, Soma Banerjee","doi":"10.1177/15910199241265590","DOIUrl":"10.1177/15910199241265590","url":null,"abstract":"<p><p>BackgroundThe superiority of endovascular thrombectomy (EVT) over medical management was not established in two early basilar artery occlusion (BAO) randomized controlled trials. Despite this, many clinicians recommended EVT for acute BAO under certain circumstances. This paper aims to compare physicians' diagnostic and management strategies of BAO according to gender.MethodsFrom January to March 2022 an international survey was conducted regarding management strategies in acute BAO. We compared responses between clinicians by identifying gender. Questions were designed to examine clinical and imaging parameters influencing management of patients with BAO.ResultsAmong the 1245 respondents from 73 countries, 311 (25.0%) identified as female. This figure was 13.6% amongst interventionists. Geographically, female respondents were lowest in Asia (14.5%) and North America (23.9%). The proportion of respondents identifying as female was consistent regardless of their years of experience. Female respondents were more likely to choose time of onset as time of first estimated stroke like symptom (48.0% vs. 38.5%, <i>p</i> < .01), were less likely to favor thrombectomy in the V4 segment of vertebrobasilar artery occlusions (31.5% vs. 43.3%, <i>p</i> < .01), and were less likely to find it acceptable to enroll all patients who met trial criteria in the standard medical treatment arm of a clinical trial (41.2% vs. 47.0%, <i>p</i> = .01). Male respondents were more likely to agree that thrombolysis would not alter their decision on proceeding with EVT (93.7% vs. 88.3%, <i>p</i> < .01).ConclusionsFemale clinicians appear to be significantly underrepresented in stroke medicine. This is most pronounced amongst interventionists and in Asia. Although male and female opinions were closely aligned on many aspects of BAO management, differences in opinion were observed in a number of significant areas which influence decision making.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2208-2218"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of demographic and clinical factors on in-hospital delays in acute ischemic stroke treatment.","authors":"Jonathan Naftali, Gal Tsur, Eitan Auriel, Guy Raphaeli, Michael Findler, Ran Brauner, Alain Perlow, Ophir Keret, Rani Barnea","doi":"10.1177/15910199241264326","DOIUrl":"10.1177/15910199241264326","url":null,"abstract":"<p><p>BackgroundDelays in reperfusion treatment, both intravenous thrombolysis (IVT) and endovascular treatment (EVT), adversely affect outcomes in patients with acute ischemic stroke (AIS). To alleviate these delays, it is essential to comprehend how patients' baseline and stroke characteristics impact in-hospital reperfusion delays. While demographic and socioeconomic factors affect stroke outcomes, their impact on in-hospital delays remains unclear.MethodThis is retrospective analysis at a tertiary stroke center, encompassing AIS patients receiving IVT and / or EVT between 2019 and 2022 (re-canalization cohort). Outcomes of interest were time intervals of admission to CT and admission to recanalization. Univariable analyses explored age, gender, baseline functional status, socioeconomic status (SES), ethnicity, vascular risk factors, and stroke characteristics. Subsequently, multivariable logistic regression analyses were performed.ResultsAltogether, 313 patients treated with IVT and 293 with EVT were included in the re-canalization cohort. No demographic variables were found to be associated with stroke treatment time intervals. Following multivariable analysis, stroke severity (low NIHSS, <i>p</i> < 0.01), arrival to the hospital by other means than ambulance (<i>p</i> < 0.01), and atypical stroke symptoms (<i>p</i> < 0.01), were associated with in-hospital delays, both in the EVT and the IVT groups.ConclusionOur findings indicate that patients with a more severe ischemic stroke, typical stroke symptoms, and arrival by ambulance have shorter stroke treatment time intervals. These results emphasize that, in atypical cases, even a lower suspicion of stroke should promote urgent workup for stroke diagnosis. Our findings do not indicate any influence of demographic or SES on in-hospital reperfusion delays.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2135-2142"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}