Interventional Neuroradiology最新文献

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Silk vista baby flow diversion beyond the circle of Willis: A single-center experience with long-term outcomes. 威利斯圈外的丝绸VISTA婴儿血流分流术:单中心经验与长期疗效。
IF 1.5 4区 医学
Interventional Neuroradiology Pub Date : 2024-10-03 DOI: 10.1177/15910199241285504
Natália Vasconcellos de Oliveira Souza, Vitor Hugo Benalia, Diego Alejandro Ortega Moreno, Eileen Liu, Vanessa Chan, Aditya Bharatha, Thomas R Marotta, Julian Spears, Vitor Mendes Pereira
{"title":"Silk vista baby flow diversion beyond the circle of Willis: A single-center experience with long-term outcomes.","authors":"Natália Vasconcellos de Oliveira Souza, Vitor Hugo Benalia, Diego Alejandro Ortega Moreno, Eileen Liu, Vanessa Chan, Aditya Bharatha, Thomas R Marotta, Julian Spears, Vitor Mendes Pereira","doi":"10.1177/15910199241285504","DOIUrl":"https://doi.org/10.1177/15910199241285504","url":null,"abstract":"<p><strong>Introduction: </strong>There is a lack of evidence of flow diversion (FD) safety for aneurysms treatment beyond the circle of Willis. Therefore, we provide a single-center real-world experience with the Silk Vista Baby (SVB).</p><p><strong>Methods: </strong>A single-center database was retrospectively reviewed for aneurysms treated with SVB flow diverters. Demographic information, clinical presentation, radiographic characteristics, procedural complications, and outcomes were assessed.</p><p><strong>Results: </strong>About 57 patients (66.7% female, mean age 54.3 ± 13.2) encompassing 57 aneurysms were included. Overall, 40.4% were ruptured: 68.4% saccular, 17.5% blister, 8.7% fusiform, and 5.3% dissecting. The majority were in the anterior circulation (68.4%), and in 48.2% of cases, the distal vessel diameter was inferior to 2 mm. The symptomatic ischemic rate was 5.2%, with one case due to in-stent thrombosis (1.8%). There were no hemorrhagic complications. Complication rates did not differ between ruptured and unruptured lesions (p = 0.356). There were no cases of delayed aneurysm rupture, and overall mortality was 1.8%. The median follow-up time was 18 ± 12 months. In-stent stenosis rate was 10.5% (6/57), all of which were asymptomatic. At the last follow-up, 70.2% of cases had an adequate occlusion (OKM C and D), and 96.5% had an mRS of 0-2.</p><p><strong>Conclusion: </strong>In our series, SVB was shown to be a safe device in the treatment of not only distal anterior circulation aneurysms but also in the management of complex posterior fossa and ruptured blister aneurysms. Multicenter studies are needed to confirm and generalize these results.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety and efficacy of coated flow diverters in the treatment of cerebral aneurysms during single antiplatelet therapy: A multicenter study. 涂层血流分流器在单一抗血小板疗法中治疗脑动脉瘤的安全性和有效性:一项多中心研究。
IF 1.5 4区 医学
Interventional Neuroradiology Pub Date : 2024-10-03 DOI: 10.1177/15910199241286542
Lukas Goertz, Sophia Hohenstatt, Dominik F Vollherbst, Charlotte S Weyland, Omid Nikoubashman, Christian Gronemann, Muriel Pflaeging, Eberhard Siebert, Georg Bohner, David Zopfs, Marc Schlamann, Thomas Liebig, Franziska Dorn, Martin Wiesmann, Markus A Möhlenbruch, Christoph Kabbasch
{"title":"Safety and efficacy of coated flow diverters in the treatment of cerebral aneurysms during single antiplatelet therapy: A multicenter study.","authors":"Lukas Goertz, Sophia Hohenstatt, Dominik F Vollherbst, Charlotte S Weyland, Omid Nikoubashman, Christian Gronemann, Muriel Pflaeging, Eberhard Siebert, Georg Bohner, David Zopfs, Marc Schlamann, Thomas Liebig, Franziska Dorn, Martin Wiesmann, Markus A Möhlenbruch, Christoph Kabbasch","doi":"10.1177/15910199241286542","DOIUrl":"https://doi.org/10.1177/15910199241286542","url":null,"abstract":"<p><strong>Objective: </strong>This multicenter study evaluates the safety and efficacy of coated flow diverters (cFDs) for the treatment of cerebral aneurysms under single antiplatelet therapy (SAPT).</p><p><strong>Methods: </strong>This is a retrospective, observational study of 41 patients (median age: 58 years) with 41 aneurysms (median size: 7 mm, 29 [71%] saccular, 9 [22%] ruptured) treated with cFDs at four neurovascular centers between 2020 and 2023. Scheduled cases received continuous SAPT starting seven days before the procedure. Emergency cases were treated with tirofiban followed by SAPT loading. The safety endpoint was ischemic complications occurring during the procedure and within four months of clinical follow-up.</p><p><strong>Results: </strong>The Pipeline Vantage or Flex Shield was used in 26 (63%) procedures, the FRED X in 12 (29%), the p48/64 Hydrophilic Polymer Coating in 2 (5%), and the Derivo Embolization Device 2heal in 1 (2%). Single antiplatelet therapy consisted of prasugrel in 27 (66%) patients, ticagrelor in 9 (22%), and ASA in 5 (12%). There were 2 (5%) early ischemic complications (one minor stroke and one transient ischemic attack). There were no late ischemic complications in the four-month follow-up of 35 patients. The six dropouts included four nontreatment-related deaths after subarachnoid hemorrhage and two patients with a poor outcome after subarachnoid hemorrhage. Complete and favorable occlusion rates (median: 7 months) were 75% (27/36) and 89% (32/36), respectively.</p><p><strong>Conclusions: </strong>Coated flow diverter implantation in the setting of SAPT was safe and effective and warrants confirmation in a prospective comparative trial.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance assessment of the Surpass Evolve flow diverter for the treatment of intracranial aneurysms: A systematic review and meta-analysis. Surpass Evolve 分流器治疗颅内动脉瘤的性能评估:系统回顾和荟萃分析。
IF 1.5 4区 医学
Interventional Neuroradiology Pub Date : 2024-10-03 DOI: 10.1177/15910199241284412
Aaron Rodriguez-Calienes, Juan Vivanco-Suarez, Nicole M Castillo-Huerta, David Espinoza-Martinez, Cristian Morán-Mariños, Ximena Espiritu-Vilcapoma, Valeria Rivera-Angles, Santiago Ortega-Gutierrez
{"title":"Performance assessment of the Surpass Evolve flow diverter for the treatment of intracranial aneurysms: A systematic review and meta-analysis.","authors":"Aaron Rodriguez-Calienes, Juan Vivanco-Suarez, Nicole M Castillo-Huerta, David Espinoza-Martinez, Cristian Morán-Mariños, Ximena Espiritu-Vilcapoma, Valeria Rivera-Angles, Santiago Ortega-Gutierrez","doi":"10.1177/15910199241284412","DOIUrl":"https://doi.org/10.1177/15910199241284412","url":null,"abstract":"<p><strong>Background: </strong>The Surpass Evolve (SE) has emerged as a promising alternative treatment from the flow diverter series. The utilization of the SE has gradually increased, however, there is a scarcity of comprehensive data on the solidity of this technology in the endovascular treatment of intracranial aneurysms (IAs). This meta-analysis aimed to evaluate the safety and effectiveness of the SE flow diverter.</p><p><strong>Methods: </strong>A systematic literature search from inception to April 2024 was conducted across five databases for studies involving IAs treated with the SE. The primary effectiveness outcome was the proportion of complete aneurysm occlusion at the final follow-up, and the primary safety outcome comprised a composite of early and delayed complications. Subgroup analyses based on aneurysm size, anatomical location, and rupture status were also conducted.</p><p><strong>Results: </strong>Our analysis included nine studies with 645 patients and 722 IAs. Effectiveness outcomes revealed an overall complete aneurysm occlusion rate of 69% (95% confidence interval (CI) = 58%-78%; <i>I</i><sup>2 </sup>= 72%) and a favorable aneurysm occlusion rate of 91% (95% CI = 82%-96%; <i>I</i><sup>2 </sup>= 49%). Safety outcomes demonstrated an overall complications rate of 6% (95% CI = 3%-12%; <i>I</i><sup>2 </sup>= 66%), with an early complications rate of 6% (95% CI = 4%-11%; <i>I</i><sup>2 </sup>= 0%), and a delayed complications rate of 0% (95% CI = 0%-7%; <i>I</i><sup>2 </sup>= 0%).</p><p><strong>Conclusions: </strong>Our findings suggest a favorable outcome with a high rate of complete aneurysm occlusion at the last follow-up, with acceptable rates of neurological complications. Future research efforts should focus on larger, prospective studies with standardized outcome measures to further elucidate the clinical utility of the SE flow diverter in the management of IAs.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emergent endovascular treatment versus medical treatment for acute large vessel occlusions with nondisabling symptoms. 对于伴有非致残症状的急性大血管闭塞,紧急血管内治疗与药物治疗的对比。
IF 1.5 4区 医学
Interventional Neuroradiology Pub Date : 2024-10-03 DOI: 10.1177/15910199241286551
Aysenur Onalan, Erdem Gurkas, Ferhat Balgetir, Emrah Aytac, Cetin Kursad Akpinar, Hasan Cetin, Asli Ciftaslan, Sule Kavak Genc
{"title":"Emergent endovascular treatment versus medical treatment for acute large vessel occlusions with nondisabling symptoms.","authors":"Aysenur Onalan, Erdem Gurkas, Ferhat Balgetir, Emrah Aytac, Cetin Kursad Akpinar, Hasan Cetin, Asli Ciftaslan, Sule Kavak Genc","doi":"10.1177/15910199241286551","DOIUrl":"https://doi.org/10.1177/15910199241286551","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study is to analyze the effectiveness and safety of medical treatment (MT) versus endovascular treatment (EVT) in acute large vessel occlusion patients with mild nondisabling stroke symptoms.</p><p><strong>Methods: </strong>This study is a multicenter observational study in which data from patients at three stroke centers were prospectively obtained and retrospectively analyzed. Patients were included if they arrived for treatment within 6 h of stroke onset or last known well time and had a baseline National Institutes of Health Stroke Scale (NIHSS) score of ≤5. Primary outcome was modified Rankin Scale (mRS) score 0-2 at 90 days. Secondary outcomes included symptomatic intracranial hemorrhage (sICH), discharge NIHSS score, 90-day all-cause mortality and length of stay. Clinical outcomes were compared through a multivariable logistic regression after adjusting for age, treatment type admission and discharge NIHSS score, admission Alberta Stroke Program Early CT (ASPECT) score and length of stay.</p><p><strong>Results: </strong>Of the 82 patients included in the study, 42 were in the EVT group and 40 were in the MT group. The groups were similar in age (MT:66, EVT:64 age; <i>p </i>= .62), gender (MT:55%, EVT:54.8%; male) admission NIHSS score (MT:2, EVT:3 points; <i>p </i>= .26), ASPECT score (MT:10, EVT:9; <i>p</i> = .15). While discharge NIHSS score was found to be statistically significant between the groups (MT:1, EVT:2; <i>p </i>= .04). There was no difference between the two groups in terms of 90-day mRS scores (MT:1, EVT:1, <i>p </i>= .86) and mortality rates (MT:4, EVT:4; <i>p </i>= .94). In unadjusted analysis, sICH rates were similar between the MT and EVT groups (MT 5%, EVT 7.1%, <i>p = </i>.52). Neurological intensive care unit length of stay (MT:5 days, EVT:2 days <i>p </i>< .001<b>)</b>, inpatient clinic length of stay (MT:3, EVT:2 days <i>p </i>= .041), and total length of stay (MT:9 days, EVT:4 days <i>p </i>< .001) were significantly longer in the MT group.</p><p><strong>Conclusions: </strong>Our multicenter study demonstrated that MT with blood pressure augmentation and anticoagulation at hyperacute stage is an alternative option for emergency large vessel occlusion patients with nondisabling mild stroke symptoms.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Barriers to stroke treatment: The price of long-distance from thrombectomy centers. 中风治疗的障碍:远离血栓切除中心的代价。
IF 1.5 4区 医学
Interventional Neuroradiology Pub Date : 2024-09-05 DOI: 10.1177/15910199241278036
Olav Søvik, Halvor Øygarden, Arnstein Tveiten, Martin Wilhelm Kurz, Kathinka Dæhli Kurz, Pål Johan Stokkeland, Hanne Brit Hetland, Hege Langli Ersdal, Per Kristian Hyldmo
{"title":"Barriers to stroke treatment: The price of long-distance from thrombectomy centers.","authors":"Olav Søvik, Halvor Øygarden, Arnstein Tveiten, Martin Wilhelm Kurz, Kathinka Dæhli Kurz, Pål Johan Stokkeland, Hanne Brit Hetland, Hege Langli Ersdal, Per Kristian Hyldmo","doi":"10.1177/15910199241278036","DOIUrl":"https://doi.org/10.1177/15910199241278036","url":null,"abstract":"<p><strong>Background: </strong>Endovascular thrombectomy, the preferred treatment for acute large-vessel occlusion stroke, is highly time-dependent. Many patients live far from thrombectomy centers due to large geographical variations in stroke services. This study aimed to explore the consequences of long transport distance on the proportion of thrombectomy-eligible patients who underwent thrombectomy, the clinical outcomes with or without thrombectomy, the timelines for patients transported, and the diagnostic accuracy of large-vessel occlusion in primary stroke centers.</p><p><strong>Methods: </strong>We conducted a retrospective observational study in a county with only primary stroke centers, ∼ 300 km from the nearest thrombectomy center. All stroke patients admitted over a year were retrieved from the Norwegian Stroke Registry. A neuroradiologist identified all computed tomography images with large-vessel occlusions. A panel determined whether these patients had a corresponding clinical indication for thrombectomy.</p><p><strong>Results: </strong>A total of 50% of the eligible patients did not receive thrombectomy. These patients had a significantly higher risk of severe disability or death compared to the patients who underwent thrombectomy. The median time from computed tomography imaging at the primary stroke center to arrival at the thrombectomy center was over 3 hours. Additionally, 30% of the large-vessel occlusions were initially undiagnosed, and half of these patients had a corresponding clinical indication for thrombectomy.</p><p><strong>Conclusions: </strong>In a county with a long transport distance to a thrombectomy center, a high proportion of eligible patients did not undergo thrombectomy, negatively impacting clinical outcomes. The transport time was considerable. A high rate of large-vessel occlusions was initially not diagnosed.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring arteriovenous malformations patient sentiments through 1401 social media posts. 通过 1401 篇社交媒体帖子探究动静脉畸形患者的情绪。
IF 1.5 4区 医学
Interventional Neuroradiology Pub Date : 2024-09-05 DOI: 10.1177/15910199241272621
Avi A Gajjar, Georgios S Sioutas, Antonio Corral-Tarbay, Mohamed M Salem, Saarang Patel, Visish M Srinivasan, Brian T Jankowitz, Jan-Karl Burkhardt
{"title":"Exploring arteriovenous malformations patient sentiments through 1401 social media posts.","authors":"Avi A Gajjar, Georgios S Sioutas, Antonio Corral-Tarbay, Mohamed M Salem, Saarang Patel, Visish M Srinivasan, Brian T Jankowitz, Jan-Karl Burkhardt","doi":"10.1177/15910199241272621","DOIUrl":"https://doi.org/10.1177/15910199241272621","url":null,"abstract":"<p><strong>Introduction: </strong>Social media has allowed patients with rare diseases to connect and discuss their experiences with others online. This study analyzed various social media platforms to better understand the patient's perception of arteriovenous malformation.</p><p><strong>Methods: </strong>Twitter, Instagram, and TikTok were searched to find posts about patients' experiences with arteriovenous malformations (AVM). Posts unrelated to the patient's experience were excluded. Posts were coded for the relevant themes related to their experience with the disease, as well as engagement, and gender.</p><p><strong>Results: </strong>The most common theme was raising awareness about the condition (87.0%). Recounting symptoms (50.2%), spreading positivity (17.5%), and survival (8.3%) were other common themes. Other prevalent themes were pain (5.2%) and fear of a rare disease (3.5%). Approximately half of AVM-related Instagram (47.93%) and TikTok (52.94%) posts raised awareness about the condition. Most Instagram (67.75%) and TikTok (89.71%) posts focused on recovery and rehabilitation. Most TikTok posts discussed \"survival\" or \"death\" (57.35%), while the majority focused on spreading positivity (79.41%). Most posts were made by women (69.6%). Females were more likely than males to post about the scientific explanation of AVMs (<i>p</i> = 0.003).</p><p><strong>Conclusion: </strong>Social media allows patients across the country and the globe to discuss their experiences with uncommon diseases and connect with others. It also allows AVM patients to share their experiences with other patients and the public.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare neurovascular variants that you probably have not seen before. 您可能从未见过的罕见神经血管变异。
IF 1.5 4区 医学
Interventional Neuroradiology Pub Date : 2024-08-28 DOI: 10.1177/15910199241272718
Mohamad Abdalkader, Samuel Z Hanz, Eytan Raz, Marialuisa Zedde, Wei Hu, Rosario Pascarella, Zhongming Qiu, Raghid Kikano, Thanh N Nguyen
{"title":"Rare neurovascular variants that you probably have not seen before.","authors":"Mohamad Abdalkader, Samuel Z Hanz, Eytan Raz, Marialuisa Zedde, Wei Hu, Rosario Pascarella, Zhongming Qiu, Raghid Kikano, Thanh N Nguyen","doi":"10.1177/15910199241272718","DOIUrl":"https://doi.org/10.1177/15910199241272718","url":null,"abstract":"<p><strong>Background: </strong>Recognition of neurovascular variants is crucial for safe endovascular and neurosurgical interventions. We aim to review and highlight various uncommon neurovascular variants and anomalies with a discussion of their relevant embryology and pathology.</p><p><strong>Methods: </strong>A retrospective review of a prospectively maintained neurovascular database was performed to identify uncommon neurovascular variants and anomalies. A pictorial review of these neurovascular findings is provided along with relevant embryological development, clinical significance, and potential pathological associations.</p><p><strong>Results: </strong>A pictorial review of selected neurovascular variants and anomalies is presented. These entities, divided between intra- and extra-cranial findings, include infra-optic origin of the anterior cerebral artery, meningo-ophtalmic artery, duplicated posterior cerebral artery, duplicate middle cerebral artery (MCA), MCA fenestration, twig-like MCA, pure arterial malformation, corkscrew basilar artery, persistent hypoglossal artery, persistent trigeminal artery and its variants, direct branches from the common carotid and cervical internal carotid arteries (ICA) (ascending pharyngeal artery from the ICA, thyroidal arteries from the CCA/brachiocephalic, arteria thyroidea ima), and extra-cranial carotid fenestration. The angiographic findings of these entities are presented with relevant 3D reconstruction and multimodal cross-sectional imaging correlation when available.</p><p><strong>Conclusions: </strong>This pictorial review highlights uncommon neurovascular variants and anomalies that neuroradiologists, interventionalists, and neurosurgeons should be aware of for accurate diagnosis and safe interventions.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep venous outflow as a surrogate for collaterals in late-window patients with successful revascularization from the DEFUSE 3 cohort. DEFUSE 3 队列中血管再通成功的晚窗口期患者的深静脉外流作为袢的替代物。
IF 1.5 4区 医学
Interventional Neuroradiology Pub Date : 2024-08-28 DOI: 10.1177/15910199241276905
Gautam Adusumilli, Tobias D Faizy, Soren Christensen, Michael Mlynash, Yince Loh, Gregory W Albers, Maarten G Lansberg, Jens Fiehler, Jeremy J Heit
{"title":"Deep venous outflow as a surrogate for collaterals in late-window patients with successful revascularization from the DEFUSE 3 cohort.","authors":"Gautam Adusumilli, Tobias D Faizy, Soren Christensen, Michael Mlynash, Yince Loh, Gregory W Albers, Maarten G Lansberg, Jens Fiehler, Jeremy J Heit","doi":"10.1177/15910199241276905","DOIUrl":"https://doi.org/10.1177/15910199241276905","url":null,"abstract":"<p><strong>Background: </strong>Deep venous outflow (VO) may be an important surrogate marker of collateral blood flow in acute ischemic stroke patients with a large vessel occlusion (AIS-LVO). Researchers have yet to determine the relationship between deep VO status in late-window patients and imaging measures of collaterals, which are key in preserving tissue.</p><p><strong>Materials and methods: </strong>We performed a multicenter retrospective cohort study on a subset of DEFUSE 3 patients recruited across 38 centers between May 2016 and May 2017 who underwent successful thrombectomy revascularization. Internal cerebral vein opacification was scored on a scale of 0-2. This metric was added to the cortical vein opacification score to derive the comprehensive VO (CVO) score from 0 to 8. Patients were stratified by favorable (ICV+) and unfavorable (ICV-) ICV scores, and similarly CVO+ and CVO-. Analyses comparing outcomes were primarily conducted by Mann-Whitney <i>U</i> and χ<sup>2</sup> tests.</p><p><strong>Results: </strong>Forty-five patients from DEFUSE 3 were scored and dichotomized into CVO+, CVO-, ICV+, and ICV- categories, with comparable demographics. Hypoperfusion intensity ratio, a marker of tissue level collaterals, was significantly worse in the ICV- and CVO- groups (p = 0.005). ICV- alone was also associated with a larger perfusion lesion (138 ml vs 87 ml; p = 0.023). No significant differences were noted in functional and safety outcomes.</p><p><strong>Conclusions: </strong>Impaired deep venous drainage alone may be a marker of poor tissue level collaterals and a greater degree of affected tissue in AIS-LVO patients presenting in the late-window who subsequently undergo successful revascularization.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spinal arteriovenous fistula leading to acute paraplegia after a lumbar nerve root block: Successful embolization with complete neurological recovery-a case report. 腰神经根阻滞术后导致急性截瘫的脊髓动静脉瘘:成功栓塞,神经功能完全恢复--病例报告。
IF 1.5 4区 医学
Interventional Neuroradiology Pub Date : 2024-08-28 DOI: 10.1177/15910199241276578
Diego Gonzalez-Morgado, Marta de Dios-Lascuevas, Ferran Blasco-Casado, Xurxo Segura-Navarro, Alejandro Tomasello-Weitz, Carlos Piñana, Sleiman Haddad
{"title":"Spinal arteriovenous fistula leading to acute paraplegia after a lumbar nerve root block: Successful embolization with complete neurological recovery-a case report.","authors":"Diego Gonzalez-Morgado, Marta de Dios-Lascuevas, Ferran Blasco-Casado, Xurxo Segura-Navarro, Alejandro Tomasello-Weitz, Carlos Piñana, Sleiman Haddad","doi":"10.1177/15910199241276578","DOIUrl":"https://doi.org/10.1177/15910199241276578","url":null,"abstract":"<p><p>Spinal arteriovenous fistulas (SAVFs) are the most common type of vascular malformation of the spine in adult patients. They can lead to acute or progressive myelopathy due to venous congestion of the medullary veins. While most SAVFs are acquired, their pathophysiology remains unclear. The natural history of the disease and its clinical presentation are highly influenced by the location of the fistula and various factors may trigger sudden neurological decline. We present a case of a patient who developed a complete spinal cord injury after a lumbar nerve root block, likely due to an undiagnosed SAVF. The patient underwent endovascular embolization, resulting in a complete recovery of neurological function.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anatomical navigational difficulties in transradial right carotid artery stenting with 7-F Optimo balloon guide catheter. 使用 7-F Optimo 球囊导引导管进行经桡动脉右颈动脉支架植入术的解剖学导航困难。
IF 1.5 4区 医学
Interventional Neuroradiology Pub Date : 2024-08-27 DOI: 10.1177/15910199241276906
Kei Arakawa, Kei Harada, Masahito Kajihara, Ryuichiro Kiyosawa, Daichi Baba, Takatsugu Oshima
{"title":"Anatomical navigational difficulties in transradial right carotid artery stenting with 7-F Optimo balloon guide catheter.","authors":"Kei Arakawa, Kei Harada, Masahito Kajihara, Ryuichiro Kiyosawa, Daichi Baba, Takatsugu Oshima","doi":"10.1177/15910199241276906","DOIUrl":"https://doi.org/10.1177/15910199241276906","url":null,"abstract":"<p><strong>Objectives: </strong>Carotid artery stenting (CAS) using a 7-F Optimo balloon guide catheter (BGC) via the right radial artery (RA) was performed for stenosis of the right carotid artery. The factors affecting the difficulty in navigating the BGC from the right RA to the right common carotid artery (CCA) were investigated.</p><p><strong>Materials and methods: </strong>For 40 cases of stenosis of the right carotid artery, CAS using a 7-F Optimo BGC via the right RA was performed. Pre-operative anatomical length and angle of the access route were retrospectively examined.</p><p><strong>Results: </strong>The 7-F Optimo BGC successfully reached all lesions; however, navigational difficulties were encountered in seven out of 40 cases (17.5%). One case in the difficult group experienced an ischemic complication. The height from the topmost point of the subclavian artery (SA) to the origin of the SA (SA height) was 44.4 mm versus 28.1 mm (<i>p</i> < 0.01), and the angle between the SA and the CCA (SA-CCA angle) was 21.6° versus 47.9° (<i>p</i> < 0.01) in the difficult and easy groups, respectively. For lesions with difficult navigation, the sensitivity and specificity of the SA height >34 mm were 100% and 82%, and the sensitivity and specificity of the SA-CCA angle <30° were 100% and 82%.</p><p><strong>Conclusions: </strong>For stenosis of the right carotid artery, transradial-CAS using a 7-F Optimo BGC is a safe procedure. However, navigating the BGC becomes difficult when the SA height is >34 mm and the SA-CCA angle is <30°.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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