Amir Molaie, Nickolas Idrogo, Naoki Kaneko, May Nour, Latisha Sharma, David S Liebeskind, Gary Duckwiler, Viktor Szeder
{"title":"Technical considerations in endovascular thrombectomy for distal vessel occlusions.","authors":"Amir Molaie, Nickolas Idrogo, Naoki Kaneko, May Nour, Latisha Sharma, David S Liebeskind, Gary Duckwiler, Viktor Szeder","doi":"10.1177/15910199261497569","DOIUrl":"10.1177/15910199261497569","url":null,"abstract":"<p><p>The role of endovascular thrombectomy (EVT) in acute ischemic stroke due to distal vessel occlusions (DVOs) remains to be clarified. Anatomical complexities in the distal vasculature, such as tortuosity and vessel fragility, render technique selection particularly paramount during EVT. Herein, we present two illustrative cases of anatomically similar DVOs treated with two different techniques at a single institution to frame a discussion of important procedural considerations during EVT for DVO.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"15910199261497569"},"PeriodicalIF":1.9,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13661814/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed Abdelsalam, Hayes B Fountain, Ian A Ramsay, Evan M Luther, Mohammad Mahdi Sowlat, Michael A Silva, Ameer E Hassan, Aman B Patel, Tiffany Eatz, Pradeep Joseph, Robert W Regenhardt, Sudhakar R Satti, Adnan H Siddiqui, Sai Sanikommu, Ammad A Baig, Priyank Khandelwal, Alejandro M Spiotta, Robert M Starke
{"title":"First multicenter study evaluating the utility of the BENCHMARK<sup>TM</sup> BMX<sup>TM</sup> 81 large-bore access catheter in neurovascular interventions.","authors":"Ahmed Abdelsalam, Hayes B Fountain, Ian A Ramsay, Evan M Luther, Mohammad Mahdi Sowlat, Michael A Silva, Ameer E Hassan, Aman B Patel, Tiffany Eatz, Pradeep Joseph, Robert W Regenhardt, Sudhakar R Satti, Adnan H Siddiqui, Sai Sanikommu, Ammad A Baig, Priyank Khandelwal, Alejandro M Spiotta, Robert M Starke","doi":"10.1177/15910199241262848","DOIUrl":"10.1177/15910199241262848","url":null,"abstract":"<p><p>IntroductionThis study is the first multicentric report on the safety, efficacy, and technical performance of utilizing a large bore (0.081″ inner diameter) access catheter in neurovascular interventions.MethodsData were retrospectively collected from seven sites in the United States for neurovascular procedures via large bore 0.081″ inner diameter access catheter (Benchmark BMX81, Penumbra, Inc.). The primary outcome was technical success, defined as the access catheter reaching its target vessel. Safety outcomes included periprocedural device-related and access site complications.ResultsThere were 90 consecutive patients included. The median age of the patients was 63 years (IQR: 53, 68); 53% were female. The most common interventions were aneurysm embolization (33.3%), carotid stenting (12.2%), and arteriovenous malformation embolization (11.1%). The transradial approach was most used (56.7%), followed by transfemoral (41.1%). Challenging anatomic variations included severe vessel tortuosity (8/90, 8.9%), type 2 aortic arch (7/90, 7.8%), type 3 aortic arch (2/90, 2.2%), bovine arch (2/90, 2.2%), and severe angle (<30°) between the subclavian artery and target vessel (1/90, 1.1%). Technical success was achieved in 98.9% of the cases (89/90), with six cases requiring a switch from radial to femoral (6.7%) and one case from femoral to radial (1.1%). There were no access site complications or complications related to the 0.081″ catheter. Two postprocedural complications occurred (2.2%), unrelated to the access catheter.ConclusionThe BMX™ 81 large-bore access catheters was safe and effective in both radial and femoral access across a wide range of neurovascular procedures, achieving high technical success without any access site or device-related complications.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2103-2109"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141428083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David A Zarrin, Fahad J Laghari, Jessica K Campos, Benjamen M Meyer, Muhammad W Khan, Jonathan Collard de Beaufort, Gizal Amin, Narlin B Beaty, Matthew T Bender, Shuichi Suzuki, Geoffrey P Colby, Alexander L Coon
{"title":"Early experience with the Aristotle Colossus 0.035' macrowire for mechanical thrombectomy in 30 consecutive cases.","authors":"David A Zarrin, Fahad J Laghari, Jessica K Campos, Benjamen M Meyer, Muhammad W Khan, Jonathan Collard de Beaufort, Gizal Amin, Narlin B Beaty, Matthew T Bender, Shuichi Suzuki, Geoffrey P Colby, Alexander L Coon","doi":"10.1177/15910199241299480","DOIUrl":"10.1177/15910199241299480","url":null,"abstract":"<p><p>IntroductionRecent literature continues to demonstrate the successful role of large-bore aspiration catheters in thrombus ingestion during mechanical thrombectomy. However catheter-to-microwire step-off and distal navigation are ongoing challenges in thrombectomy. A new to market 0.035' macrowire (Aristotle 35 Colossus Guidewire, Scientia Vascular, West Vale City, UT) may address such challenges. We report here our early experience in 30 mechanical thrombectomy cases.Materials and MethodsWe analyzed a prospectively maintained database of the senior authors to identify cases utilizing a 0.035' macrowire with 0.035' aspiration catheters for mechanical thrombectomy.ResultsThirty consecutive cases were identified. Seventeen (57%) patients were female with an average age of 75.3 ± 2.2 years (range 55-97). Average presenting NIHSS was 13.0 ± 1.7. Thrombus locations included 7% (<i>n</i> = 2) in the cervical ICA, 47% (<i>n</i> = 14) in the M1, 43% (<i>n</i> = 13) in the M2, and 3% (<i>n</i> = 1) in the P1. An 088' ID aspiration catheter was navigated to at least the M1 segment in all anterior circulation cases and the basilar in the posterior circulation case. The 0.035' macrowire was placed proximal to the occlusion in all cases allowing coaxial 035' and 071' catheter aspiration passes. TICI 2C/3 was achieved in 87% of cases (<i>n</i> = 26) and TICI 2B in the remaining cases. There were no wire-related perforations or vessel dissections.ConclusionThe Colossus 0.035' macrowire may offer advantages over its smaller counterparts by reducing ledge effect and the need to cross the thrombus. Further comparative studies against currently available microwires in various anatomies are warranted.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2566-2571"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anatomical navigational difficulties in transradial right carotid artery stenting with 7-F Optimo balloon guide catheter.","authors":"Kei Arakawa, Kei Harada, Masahito Kajihara, Ryuichiro Kiyosawa, Daichi Baba, Takatsugu Oshima","doi":"10.1177/15910199241276906","DOIUrl":"10.1177/15910199241276906","url":null,"abstract":"<p><p>ObjectivesCarotid artery stenting (CAS) using a 7-F Optimo balloon guide catheter (BGC) via the right radial artery (RA) was performed for stenosis of the right carotid artery. The factors affecting the difficulty in navigating the BGC from the right RA to the right common carotid artery (CCA) were investigated.Materials and MethodsFor 40 cases of stenosis of the right carotid artery, CAS using a 7-F Optimo BGC via the right RA was performed. Pre-operative anatomical length and angle of the access route were retrospectively examined.ResultsThe 7-F Optimo BGC successfully reached all lesions; however, navigational difficulties were encountered in seven out of 40 cases (17.5%). One case in the difficult group experienced an ischemic complication. The height from the topmost point of the subclavian artery (SA) to the origin of the SA (SA height) was 44.4 mm versus 28.1 mm (<i>p</i> < 0.01), and the angle between the SA and the CCA (SA-CCA angle) was 21.6° versus 47.9° (<i>p</i> < 0.01) in the difficult and easy groups, respectively. For lesions with difficult navigation, the sensitivity and specificity of the SA height >34 mm were 100% and 82%, and the sensitivity and specificity of the SA-CCA angle <30° were 100% and 82%.ConclusionsFor stenosis of the right carotid artery, transradial-CAS using a 7-F Optimo BGC is a safe procedure. However, navigating the BGC becomes difficult when the SA height is >34 mm and the SA-CCA angle is <30°.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2258-2263"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Justin E Vranic, Robert W Regenhardt, Amine Awad, Omer Doron, James Rabinov
{"title":"Endovascular and medical management strategies for carotid-cavernous fistulas: A safety and efficacy analysis.","authors":"Justin E Vranic, Robert W Regenhardt, Amine Awad, Omer Doron, James Rabinov","doi":"10.1177/15910199241261761","DOIUrl":"10.1177/15910199241261761","url":null,"abstract":"<p><p>BackgroundCarotid-cavernous fistulas (CCFs) are complex arteriovenous shunting lesions of the cavernous sinus with diverse clinical presentations. This study aimed to analyze clinical outcomes and differentiate patients treated with conservative observation versus those needing endovascular intervention.MethodsA retrospective analysis of 84 patients with angiographically confirmed CCF was conducted from 2000 to 2022. Endovascular treatment decisions were made at the discretion of neurointerventionalists. Clinical and angiographic data were collected, including Barrow CCF classification and treatment outcomes.ResultsPatients managed conservatively (<i>n</i> = 17) had longer symptom duration (165 vs 42 days) and more indirect CCF (100% vs 68%) compared to those treated with endovascular embolization (<i>n</i> = 67). High-risk clinical symptoms, including proptosis, diplopia, decreased visual acuity, and chemosis, were more common in the embolization group. Cortical venous reflux and ophthalmic venous reflux were more prevalent in the embolization group (39% and 91%, respectively). Overall, 31% of embolized CCFs required retreatment, mainly Barrow type D lesions (65%). Transvenous coil embolization was the primary technique used (78%), followed by feeder artery embolization (16%), and internal carotid artery flow diversion (8%).ConclusionIn selected CCF patients without high-risk symptoms or angiographic features, conservative observation is a safe and effective alternative to endovascular embolization. High-risk symptoms and angiographic features favor endovascular intervention. Complications were rare, and most were transient, emphasizing the safety of endovascular management. Longitudinal angiographic and ophthalmologic surveillance is essential for monitoring fistula persistence or recurrence.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2088-2095"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141332261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diwas Gautam, Omid Shoraka, Sarah Nguyen, Michael T Bounajem, Aaron Shoskes, Jennifer Juhl Majersik, Robert C Rennert, Craig Kilburg, Karol P Budohoski, Ramesh Grandhi
{"title":"Endovascular treatment of cerebral venous sinus thrombosis: A systematic review and meta-analysis of efficacy based on technique.","authors":"Diwas Gautam, Omid Shoraka, Sarah Nguyen, Michael T Bounajem, Aaron Shoskes, Jennifer Juhl Majersik, Robert C Rennert, Craig Kilburg, Karol P Budohoski, Ramesh Grandhi","doi":"10.1177/15910199251336946","DOIUrl":"10.1177/15910199251336946","url":null,"abstract":"<p><p>BackgroundCerebral venous sinus thrombosis (CVST) is rare but potentially life-threatening. Although systemic anticoagulation is the primary treatment, endovascular thrombectomy (EVT) or thrombolysis may be considered for refractory cases. Considering advanced techniques and device technology, we undertook an updated systematic review and meta-analysis to evaluate clinical and radiographic outcomes for treating CVST.MethodsWe searched PubMed and EMBASE for studies describing CVST patients treated with EVT. Presenting symptoms, procedural details, and clinical and radiographic outcomes were analyzed. Random-effects models were generated to calculate pooled proportions of clinical and radiographic outcome variables.ResultsWe analyzed 26 studies comprising 273 patients (mean age 37 years, 57.7% female). Preprocedural intracranial hemorrhage was present in 167/243 (67.1%) patients. Endovascular thrombectomy techniques included aspiration thrombectomy alone (29.3%), aspiration plus stent retriever (19%), stent retriever alone (12.5%), balloon/catheter maceration (6.6%), and AngioJet rheolytic system (32.6%). Random-effects model indicated that 37% of patients had complete recanalization and 57% had partial recanalization. The model indicated that 79% of patients had a good clinical outcome (modified Rankin Scale score 0-2) at last follow-up. There were no statistically significant differences between modern systems (stent retriever and/or aspiration) and older systems (rheolytic thrombectomy and catheter maceration). Aspiration alone yielded a significantly higher frequency of good clinical outcomes compared with the combined technique (83.8% vs. 61.5%, <i>p</i> = 0.004).ConclusionEndovascular thrombectomy for CVST refractory to systemic anticoagulation achieved high recanalization rates, favorable outcomes, and low procedural complication rates. Modern and older techniques exhibited similar safety and efficacy. These findings support EVT as an effective treatment option.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2634-2647"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Steven G Roth, Seoiyoung Ahn, Campbell Liles, Lohit Velagapudi, Nishit Mummareddy, Yeji Ko, Austin M Hilvert, Michael T Froehler, Matthew R Fusco, Rohan V Chitale
{"title":"Analysis of selective neurocritical care admission costs following elective endovascular treatment of unruptured intracranial aneurysms.","authors":"Steven G Roth, Seoiyoung Ahn, Campbell Liles, Lohit Velagapudi, Nishit Mummareddy, Yeji Ko, Austin M Hilvert, Michael T Froehler, Matthew R Fusco, Rohan V Chitale","doi":"10.1177/15910199241288880","DOIUrl":"10.1177/15910199241288880","url":null,"abstract":"<p><p>IntroductionNo consensus exists on the necessity of neurocritical care unit (NCU)-level care following unruptured intracranial aneurysm (UIA) treatment. We aim to identify patients requiring NCU-level care post-treatment and determine potential cost savings utilizing a selective NCU admission protocol.MethodsA retrospective analysis of all UIA patients who underwent endovascular treatment at a single center from 2017-2022 was conducted. Data on demographics, preprocedural variables, radiographic features, procedural techniques, intra/postoperative events, and length of stay (LOS) were collected. Multivariable analysis was performed to identify patients requiring NCU-level care post-treatment. Cost analysis using hospital cost data (not charges/reimbursement) was performed using simulated step-down and floor protocols for patients without NCU indications following a hypothetical six-hour post-anesthesia care unit observation period.ResultsOf 209 patients, 179 were discharged within 24 h and 30 had prolonged LOS. In our analysis, intra- and postoperative events independently predicted prolonged LOS. In our subanalysis, 47 patients demonstrated NCU needs: 24 with intraoperative indications, 18 with postoperative indications, and five with both. Of the 23 with postoperative indications, 20 were identified within six hours, while three were identified within six to 24 h. The median variable cost per patient for the current NCU protocol was $31,505 (IQR, $26,331-$37,053) vs. stepdown protocol $29,514 (IQR, $24,746-$35,011;p = 0.061) vs. floor protocol $26,768 (IQR, $22,214-$34,107;p < 0.001). Total variable costs were $6,211,497 for the current NCU protocol vs. $5,921,912 for the step-down protocol (4.89% savings) and $5,509,052 for the floor protocol (12.75% savings).ConclusionMost patients requiring NCU-level care following UIA treatment were identified within a six-hour postoperative window. Thus, selective NCU admission for this cohort following a six-hour observation period may be a logical avenue for cost reduction. Our analysis demonstrated 5% and 13% savings for uncomplicated patients using step-down and floor admission protocols, respectively.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2476-2483"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natália Vasconcellos de Oliveira Souza, Kevin Janot, Adam A Dmytriw, Victor Hugo Benalia, Vitor Mendes Pereira
{"title":"Traumatic occipital artery pseudoaneurysm: Case report, anatomical considerations, and literature review.","authors":"Natália Vasconcellos de Oliveira Souza, Kevin Janot, Adam A Dmytriw, Victor Hugo Benalia, Vitor Mendes Pereira","doi":"10.1177/15910199241271062","DOIUrl":"10.1177/15910199241271062","url":null,"abstract":"<p><p>We describe a case of a 22-year-old man with a traumatic occipital artery pseudoaneurysm revealed by a painful expanding neck hematoma after a penetrating knife injury. A neuroendovascular consultation was requested after a computed tomography angiogram showed active pseudoaneurysm bleeding. Anatomical considerations of the upper cervical region including dangerous anastomosis between the vertebral and internal carotid artery are discussed, illustrating how this impacted our treatment strategy. We also discuss other treatment modalities after a thorough literature review of traumatic occipital artery pseudoaneurysms.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2833-2838"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142001125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pedro Martins, Krishna Sambhu, Mohamed Tarek, Jaydevsinh Dolia, Aqueel Pabaney, Jonathan Grossberg, Raul Nogueira, Diogo Haussen
{"title":"Validation of a model for outcome prediction after endovascular treatment for ischemic stroke.","authors":"Pedro Martins, Krishna Sambhu, Mohamed Tarek, Jaydevsinh Dolia, Aqueel Pabaney, Jonathan Grossberg, Raul Nogueira, Diogo Haussen","doi":"10.1177/15910199241265134","DOIUrl":"10.1177/15910199241265134","url":null,"abstract":"<p><p>IntroductionThe recently developed MR-PREDICTS@24 h model showed excellent performance in the MR-CLEAN Registry cohort in patients presenting within 12 h from onset. However, its applicability to an U.S. population and to patients presenting beyond 12 h from last known normal are still undetermined. We aim to externally validate the MR-PREDICTS@24 h model in a new geographic setting and in the late window.MethodsIn this retrospective analysis of a prospectively collected database from a comprehensive stroke center in the United States, we included patients with intracranial carotid artery or middle cerebral artery M1 or M2 segment occlusions who underwent endovascular therapy and applied the MR-PREDICTS@24 h formula to estimate the probabilities of functional outcome at day 90. The primary endpoint was the modified Rankin Scale (mRS) at 90 days.ResultsWe included 1246 patients, 879 in the early (<12 h) and 367 in the late (≥12 h) cohort. For both cohorts, calibration and discrimination of the model were accurate throughout mRS levels, with absolute differences between estimated and predicted proportions ranging from 1% to 5%. Calibration metrics and curve inspections showed good performance for estimating the probabilities of mRS ≤ 1 to mRS ≤ 5 for the early cohort. For the late cohort, predictions were reliable for the probabilities of mRS ≤ 1 to mRS ≤ 4.ConclusionThe MR-PREDICTS@24 h was transferrable to a real-world U.S.-based cohort in the early window and showed consistently accurate predictions for patients presenting in the late window without need for updating.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2110-2115"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriel Marinheiro, Gabriel de Almeida Monteiro, Ivo Queiroz, Lucas M Barbosa, Antonio Mutarelli, Luíza Maria Amaral Tanus, Pedro Henrique Reginato, Ocílio Ribeiro Gonçalves, Marcondes Pimentel Cruz, Agostinho C Pinheiro, Keven Ferreira da Ponte, Gisele Sampaio Silva, João Paulo Mota Telles
{"title":"Outcomes of patients with heart failure after thrombectomy for ischemic stroke: A systematic review and meta-analysis.","authors":"Gabriel Marinheiro, Gabriel de Almeida Monteiro, Ivo Queiroz, Lucas M Barbosa, Antonio Mutarelli, Luíza Maria Amaral Tanus, Pedro Henrique Reginato, Ocílio Ribeiro Gonçalves, Marcondes Pimentel Cruz, Agostinho C Pinheiro, Keven Ferreira da Ponte, Gisele Sampaio Silva, João Paulo Mota Telles","doi":"10.1177/15910199251328548","DOIUrl":"10.1177/15910199251328548","url":null,"abstract":"<p><p>BackgroundMechanical thrombectomy (MT) is an effective treatment for acute ischemic stroke, but its outcomes in patients with heart failure (HF) are uncertain. Some studies suggest worse outcomes in these patients, while others show no significant differences in mortality or functional recovery.MethodsWe systematically searched the MEDLINE, Embase, and Cochrane databases until August 2024. Studies were included if they compared patients with HF to those without. All statistical analyses were carried out using R, version 4.1.1. A subanalysis examined outcomes in HF patients with reduced left ventricular ejection fraction (LVEF).ResultsWe included 3587 patients, of which 1187 (33.1%) were in the HF group. We found a significantly higher mortality (RR 2.01; 95% CI: 1.33-3.03; <i>p</i> < 0.01) and lower risk of favorable neurologic outcome (RR 0.76; 95% CI: 0.67-0.86; <i>p</i> < 0.01) at 90 days on HF group, without a notable difference in the occurrence of symptomatic intracranial hemorrhage (sICH) (RR 1.57; 95% CI: 0.98-2.51; <i>p</i> = 0.06) or recanalization success (RR 1.02; 95% CI: 0.98-1.07; <i>p</i> = 0.28). HF patients with reduced LVEF also showed higher mortality (RR 1.91; 95% CI: 1.05-3.49; <i>p</i> = 0.03) and worse functional outcomes (RR 0.83; 95% CI: 0.72-0.95; <i>p</i> < 0.01) compared to those without HF.ConclusionsHF patients undergoing MT for ischemic stroke may have worse functional outcomes and higher mortality at 90 days compared to non-HF patients despite similar rates of sICH and recanalization success. Our findings suggest that patients with HF may have a worse prognosis compared to those without HF following MT for ischemic stroke.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2625-2633"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12012485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}