Interventional Neuroradiology最新文献

{"title":"Occipital venous sinus stenting for idiopathic intracranial hypertension and pulsatile tinnitus: A case series.","authors":"Kyriakos Papadimitriou, Cassidy Werner, Timothy G White, Danielle Golub, Shyle H Mehta, Justin Turpin, Kevin Shah, Athos Patsalides","doi":"10.1177/15910199241245451","DOIUrl":"10.1177/15910199241245451","url":null,"abstract":"<p><p>Venous sinus stenting for dural venous sinus outflow obstruction due to an intrinsic filling obstruction or extrinsic stenosis is an increasingly popular treatment strategy for idiopathic intracranial hypertension (IIH) and isolated pulsatile tinnitus (PT). The most common site of stenosis is the lateral venous sinus at the transverse-sigmoid junction. Approximately 10% of the population has a persistent occipital venous sinus (OVS), a variant that may be the dominant venous drainage pathway in the setting of a hypoplastic or aplastic transverse sinus. OVS stenosis has been rarely associated with IIH and isolated PT with only a handful published cases. We herein report a retrospective series of OVS stenting in five patients, four of whom presented with non-IIH PT and one with IIH.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"278-283"},"PeriodicalIF":2.1,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The United Kingdom's largest experience with Contour in the treatment of wide-neck intracranial aneurysms with long-term (2-year) follow-up.","authors":"Fathallah Ismail Islim, Rishabh Suvarna, Nayyar Saleem, Tufail Patankar","doi":"10.1177/15910199251349072","DOIUrl":"10.1177/15910199251349072","url":null,"abstract":"<p><p>Background and purposeEndovascular treatment of wide-neck bifurcation aneurysms has historically proved difficult with variable outcomes of efficacy and safety. We assessed the short- and long-term clinical and radiologic outcomes in the real-world use of Contour neurovascular system.Materials and methodsThis study was a retrospective analysis of unruptured intracranial aneurysms treated with the Contour. The primary radiologic outcomes were quantified on DSA, CTA, or MRA using the modified Raymond-Roy criteria. The outcomes were defined as complete occlusion (RROC 1) and adequate occlusion (RROC 1 and RROC 2) at 6 months and 2-years. The primary safety outcome was the rate of device-related adverse events. Secondary safety outcomes included time to discharge and change in the modified Rankin scale (mRS) score at 6-month follow-up.Results54 patients were treated with Contour from February 2017 to July 2022. 50 aneurysms underwent 6-month follow-up. 28 of 50 aneurysms treated (56%) remained completely occluded at 6-month follow-up (RROC 1), whilst 44 of 50 aneurysms treated (88%) were adequately occluded. 46 aneurysms underwent 2-year follow-up. 28 of 46 aneurysms treated (60.9%) remained completely occluded at 2-year follow-up (RROC 1), whilst 38 of 46 aneurysms (82.6%) were adequately occluded (RROC 1 and RROC2). Immediate postoperative complications occurred in 5 patients; only 1 patient (1.8%) had residual neurologic deficits at 6 months (mRS 1).ConclusionsManagement of wide-neck aneurysms remains difficult, with high rates of recurrence and complications. The use of the Contour demonstrated a promising and safe addition to the intravascular stock for the treatment of complex wide-neck aneurysms.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"221-228"},"PeriodicalIF":2.1,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12158970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare neurovascular variants that you probably have not seen before.","authors":"Mohamad Abdalkader, Samuel Z Hanz, Eytan Raz, Marialuisa Zedde, Wei Hu, Rosario Pascarella, Zhongming Qiu, Raghid Kikano, Thanh N Nguyen","doi":"10.1177/15910199241272718","DOIUrl":"10.1177/15910199241272718","url":null,"abstract":"<p><p>BackgroundRecognition of neurovascular variants is crucial for safe endovascular and neurosurgical interventions. We aim to review and highlight various uncommon neurovascular variants and anomalies with a discussion of their relevant embryology and pathology.MethodsA retrospective review of a prospectively maintained neurovascular database was performed to identify uncommon neurovascular variants and anomalies. A pictorial review of these neurovascular findings is provided along with relevant embryological development, clinical significance, and potential pathological associations.ResultsA pictorial review of selected neurovascular variants and anomalies is presented. These entities, divided between intra- and extra-cranial findings, include infra-optic origin of the anterior cerebral artery, meningo-ophtalmic artery, duplicated posterior cerebral artery, duplicate middle cerebral artery (MCA), MCA fenestration, twig-like MCA, pure arterial malformation, corkscrew basilar artery, persistent hypoglossal artery, persistent trigeminal artery and its variants, direct branches from the common carotid and cervical internal carotid arteries (ICA) (ascending pharyngeal artery from the ICA, thyroidal arteries from the CCA/brachiocephalic, arteria thyroidea ima), and extra-cranial carotid fenestration. The angiographic findings of these entities are presented with relevant 3D reconstruction and multimodal cross-sectional imaging correlation when available.ConclusionsThis pictorial review highlights uncommon neurovascular variants and anomalies that neuroradiologists, interventionalists, and neurosurgeons should be aware of for accurate diagnosis and safe interventions.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"253-267"},"PeriodicalIF":2.1,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569770/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between M1 tortuosity and intracranial hemorrhage after mechanical thrombectomy using a stent retriever for M2 occlusions.","authors":"Rikuo Nishii, Satoru Fujiwara, Yasuhiro Yamamoto, Nobuyuki Ohara, Masaomi Koyanagi, Masanori Goto, Ryu Fukumitsu, Tadashi Sunohara, Nobuyuki Fukui, Nobuyuki Sakai, Tsuyoshi Ohta","doi":"10.1177/15910199251349879","DOIUrl":"10.1177/15910199251349879","url":null,"abstract":"<p><p>BackgroundMechanical thrombectomy (MT) is an important treatment for middle cerebral artery (MCA) M2 occlusions. However, it carries a risk of intracranial hemorrhage (ICH), especially with a stent retriever. We investigated the correlation between MCA M1 tortuosity and ICH after MT using a stent retriever for M2 occlusions, along with other clinical outcomes.MethodsThis single-center, retrospective study included patients with isolated MCA M2 occlusions treated using a stent retriever. M1 tortuosity was assessed using pre-MT imaging, with patients classified into tortuous (≥ 2 angulations) and non-tortuous (≤ 1 angulation) groups. The primary outcome was any ICH. Secondary outcomes included symptomatic ICH (sICH), procedural outcomes, and functional outcomes.ResultsAmong 153 patients (median age: 78 years, 48% female), 55 (36%) had tortuous M1 segments. The tortuous group showed higher NIHSS scores (median score 19 vs. 14, <i>p</i> = 0.045) and a higher prevalence of chronic renal failure at baseline (15% vs. 4%, <i>p</i> = 0.029). Any ICH occurred in 69 patients (45%) and was more frequent in the tortuous group (64% vs. 35%, <i>p</i> = 0.003; adjusted odds ratio [aOR], 3.09; 95% confidence interval [CI], 1.48-6.42). Among the ICH subtypes, subarachnoid hemorrhage (SAH) was more common in the tortuous group (49% vs. 27%, <i>p</i> = 0.01; aOR, 2.61; 95% CI, 1.26-5.41). However, the incidence of sICH (5.5% vs. 4.1%, <i>p</i> = 0.70) and good neurological outcome at 90 days after MT (45% vs. 50%, <i>p</i> = 0.62) were comparable.ConclusionMCA M1 tortuosity was associated with a higher incidence of any ICH, particularly SAH, after MT using a stent retriever for M2 occlusions.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"229-235"},"PeriodicalIF":2.1,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12158972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffuse scalp neurofibromas: Case series and Clinicoradiological characteristics of a rare vascular lesion.","authors":"Aaron Bleakley, Guy Betts, Sajid Sainuddin, Christopher Hilditch","doi":"10.1177/15910199241267301","DOIUrl":"10.1177/15910199241267301","url":null,"abstract":"<p><p>Diffuse neurofibroma of the head and neck are rare tumours which have unique clinical and radiological findings. Presurgical diagnosis is important as these lesions are usually highly vascular and pre-operative embolisation can reduce the risk of intra-operative haemorrhage. In this article we describe four cases; two which underwent pre-operative embolisation, which should aid the reader in successfully diagnosing this entity before biopsy/surgery.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"245-252"},"PeriodicalIF":2.1,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141879739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flow diverter surface modifications for aneurysm treatment: A review of the mechanisms and data behind existing technologies.","authors":"Timothy G White, Brandon A Santhumayor, Justin Turpin, Kevin Shah, Daniel Toscano, Ina Teron, Thomas Link, Athos Patsalides, Henry H Woo","doi":"10.1177/15910199231207550","DOIUrl":"10.1177/15910199231207550","url":null,"abstract":"<p><p>Flow diversion (FD) has become a mainstay treatment for large wide-necked aneurysms. Despite excellent safety and efficacy, the risk of thromboembolic complications necessitates the use of dual antiplatelet therapy (DAPT). The use of DAPT makes hemorrhagic complications of stenting carry high morbidity and mortality. Additionally, DAPT usage carries a risk of \"nuisance\" complications that do not directly impact intracranial circulation but need to be managed nonetheless. To circumvent this issue, the most recent generation of flow diverters have undergone surface modification with various compounds to confer blood compatibility to limit clotting and thrombosis. While these newer generation flow diverters are marketed to enhance ease of deployment, the goal is to eventually facilitate single antiplatelet use with flow diverter treatment. This generation of FDs have potential to expand indications beyond unruptured wide-necked aneurysms to include ruptured intracranial aneurysms without the necessity of DAPT. Currently, no comprehensive review details the molecular mechanisms and pre-clinical and clinical data on these modifications. We seek to fill this gap in the literature by consolidating information on the coating technology for four major FDs currently in clinical use-Pipeline^TM Flex and Vantage Shield Technology^TM, FRED^TMX, p48/64 hydrophilic coating, and Acandis Dervio® 2heal-to serve as a reference guide in neurointerventional aneurysm treatment. Although the Balt silk^TM was one of the first FDs, it is uncoated, thus we will not cover this device in our review. A literature review was performed to obtain information on each coating technology for the major flow diverters currently on the market using international databases (PUBMED, Embase, Medline, Google Scholar). The search criteria used the keywords for each coating technology of interest \"phosphorylcholine,\" \"poly 2-methoxyethyl acrylate,\" \"hydrophilic polymer coating,\" and \"fibrin-heparin\" Keywords related to the device names \"Pipeline Shield,\" \"Pipeline Shield with Flex Technology,\" \"FRED,\" \"FREDX,\" \"p64,\" \"p64-HPC,\" \"Derivo 2heal\" were also used. Studies that detailed the mechanism of action of the coating, any pre-clinical studies with surface-modified intravascular devices, and any clinical retrospective series, prospective series, or randomized clinical trials with surface-modified devices for aneurysm treatment were included.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"109-125"},"PeriodicalIF":2.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12852632/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71414911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usefulness of the minimally invasive flow reversal method in carotid artery stenting: Simplified flow reversal carotid artery revascularization for radial access (SF-CARR).","authors":"Tomomichi Kayahara, Natsuki Shozuhara, Kazuki Fukumoto, Shunsuke Kido, Eisuke Tsukagoshi, Takashi Matsumoto, Toru Nakagami, Masataka Yoshimura, Shinya Kohyama","doi":"10.1177/15910199261416272","DOIUrl":"10.1177/15910199261416272","url":null,"abstract":"<p><p>BackgroundFlow reversal, achieved by occluding both the common and external carotid arteries to induce retrograde flow from the internal carotid artery, is a useful method for preventing distal embolization in cases of carotid artery stenting (CAS). The \"conventional method\" employed by our institute for CAS involves the use of one-way valves incorporated in a flow reversal system for rapid manual blood aspiration. Subsequently, we recently transitioned from the conventional method to the \"simplified flow reversal carotid artery revascularization for radial access (SF-CARR),\" in which external carotid artery occlusion is omitted while a transradial approach is implemented. This study aimed to clarify the efficacy and safety of SF-CARR in patients undergoing CAS.MethodsA retrospective study was conducted in 50 patients diagnosed with internal carotid artery stenosis between 2022 and 2025. Of these, 24 were treated with SF-CARR, while the others underwent the conventional method. We investigated patient characteristics, endovascular procedures, procedural invasiveness, including procedural time, radiation exposure, or contrast agent use, and clinical outcomes.ResultsCompared to the conventional group, a reduced procedural time (<i>p</i> = 0.001) was observed in the SF-CARR group. The radiation exposure dose (<i>p</i> = 0.020), fluoroscopy time (<i>p</i> = 0.003), amount of contrast agent injected (<i>p</i> < 0.001), and number of contrast agent injections (<i>p</i> < 0.001) were also reduced in the SF-CARR group. In addition, the transradial approach was adopted more frequently in the SF-CARR group (<i>p</i> < 0.001), and no significant differences were reported in complications or patients' outcomes between the two groups.ConclusionThis novel flow reversal method, \"SF-CARR,\" can provide minimally invasive treatment to patients with carotid artery stenosis.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"15910199261416272"},"PeriodicalIF":2.1,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12819133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146012969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echo intracranial base catheter use in neuroendovascular procedures: Institutional experience.","authors":"Maher Hosain, Samantha Miller, Alman Rehman, J El Gengaihy, Hamzah M Saei, Mohamed A Badway, Daniella Sanchez, Muhammad Khan, Ameer E Hassan","doi":"10.1177/15910199251405085","DOIUrl":"10.1177/15910199251405085","url":null,"abstract":"<p><p>BackgroundAdvanced neuroendovascular procedures require trackable and supportive guide catheters, which facilitate safe device delivery. Echo intracranial base catheter was engineered as a large lumen (0.100″ ID) access catheter that is super trackable, supportive, and kink resistance, all while fitting within the puncture of a typical 8F sheath when its used with the thin-walled, Dash short sheath (9F). This case series evaluates its performance as a guide catheter in various neurointerventional procedures.MethodsConsecutive cases using an Echo access catheter were identified from a prospectively maintained patient database at a comprehensive stroke center between April and July 2025. Demographic, clinical, procedural, and angiographic characteristics were collected. Outcomes of interest included procedural success and periprocedural complications, including flow-limiting vasospasm, vessel dissection, and thrombus formation.ResultsEcho access catheter was used in a total of eleven cases, including six thrombectomies, two venous sinus stents, one intracranial stent, one intracranial angioplasty, and one aneurysm flow diversion. Average patient age was 61 years old, 6 (54.5%) were female, and all had femoral access. Echo catheter tip was placed in the petrous segment of ICA in three cases (27.2%), the lacerum segment in three cases (27.2%), the cervical segment in two cases (18.1%), the cavernous segment in one case (9.1%), the vertical petrous segment in one case (9.1%), and the transverse sinus in one case (9.1%). Intracranial stenting and flow diversion were completed with use of a distal access catheter, and intracranial angioplasty was successfully performed with an Echo access catheter alone. Echo access catheter was able to easily navigate to the transverse venous sinus over a ledge-reducing delivery microcatheter and deliver devices for venous sinus stenting and angioplasty. There was a 100% procedural success rate. No significant catheter-related complications were observed.ConclusionsThis series highlights Echo access catheter's safe and effective use in a diverse representation of neuroendovascular procedures.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"15910199251405085"},"PeriodicalIF":2.1,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12711515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145776235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal pinching technique for recanalization: A retrospective analysis of mechanical thrombectomy in a 3D vessel model.","authors":"Yoichiro Kawamura, Atsuko Honda, Yukie Horikoshi, Patrick Brouwer","doi":"10.1177/15910199251405097","DOIUrl":"10.1177/15910199251405097","url":null,"abstract":"<p><p>ObjectiveAchieving recanalization with the few passes as possible is essential for favorable outcomes in mechanical thrombectomy (MT). However, when recanalization fails, the underlying reasons often remain unclear because device-thrombus interactions cannot be directly visualized during the procedure. We investigated how device maneuver during the pinching technique influences first pass recanalization (FPR).MethodsUsing a 3D silicone cerebrovascular model and swine thrombi, 109 MT procedures were performed by experienced neurointerventionalists under clinical use fluoroscopy, blinded to direct visualization. Real-world procedural videos were retrospectively analyzed to assess the impact of device maneuvers on FPR.ResultsThe pinching technique for non-segmented thrombus was applied in 58 cases. Advancing the aspiration catheter (AC) to achieve thrombus contact occurred in 52 cases, yielding FPR in 44 cases. Pulling the stent retriever (SR) toward the AC after contact was performed in 14 cases, all achieving FPR, compared with 32 of 44 cases without this maneuver. SR deployment after AC-thrombus contact frequently caused proximal AC displacement and loss of thrombus contact.ConclusionIn pinching technique, advancing the AC to ensure thrombus contact, followed by pulling the SR toward the AC before system retrieval, may prevent stretching, facilitate effective pinching, and improve the likelihood of achieving FPR.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"15910199251405097"},"PeriodicalIF":2.1,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12705412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145764112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a novel elastase-induced saccular aneurysm model in rats suitable for testing endovascular devices: An experimental animal study.","authors":"Yasuhito Ueki, Esref A Bayraktar, Julien Ognard, Gerard El Hajj, Yong H Ding, Daying Dai, Lorenzo Rinaldo, Ram Kadirvel, David F Kallmes","doi":"10.1177/15910199251399755","DOIUrl":"10.1177/15910199251399755","url":null,"abstract":"<p><p>BackgroundAnimal models are essential for evaluating endovascular device safety and efficacy. Rats offer advantages, such as genetic manipulability, lower cost, and shorter healing and breeding cycles, compared to large animals. These features support studying aneurysm healing mechanisms and enable high-throughput testing. We developed an optimal rat aneurysm model for device evaluation.MethodsSaccular aneurysms were created at the origins of the left renal artery (LRA) with acetylsalicylic acid (ASA) (LRA/ASA group, n = 7); the right common iliac artery (RCIA) with ASA alone (RCIA/ASA group, n = 6) or ASA plus clopidogrel (CLP) (RCIA/ASA + CLP group, n = 7); and the left common iliac artery (LCIA) with ASA + CLP (LCIA/ASA + CLP group, n = 7). The origins of these arteries were surgically exposed. During temporary ligation of the vessel origin, the vessel was bisected and endoluminal elastase was incubated in the proximal stump for 10 min, followed by release of the proximal ligation and permanent ligation of the stump. Angiographical and histological analysis were performed 4 weeks post-procedure.ResultsFollow-up digital subtraction angiography revealed mean ± standard deviation aneurysm height/neck dimensions of 1.2 ± 0.4/1.2 ± 0.1, 2.9/3.1, 2.3 ± 0.6/1.9 ± 0.3, and 2.1 ± 0.6/2.0 ± 0.4 mm for the LRA/ASA, RCIA/ASA, RCIA/ASA + CLP, and LCIA/ASA + CLP groups, respectively. The survival rate was 29%, 17%, 71%, and 86% in the LRA/ASA, RCIA/ASA, RCIA/ASA + CLP, and LCIA/ASA + CLP groups, respectively. Histopathological analysis of these aneurysms confirmed the absence of the internal elastic lamina and revealed aneurysmal changes in the arterial wall, resembling the pathological findings observed in human aneurysm specimens.ConclusionsCommon iliac aneurysm models with ASA + CLP can be used to evaluate the safety and efficacy of endovascular devices.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"15910199251399755"},"PeriodicalIF":2.1,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12705413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145764121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}