Interventional Neuroradiology最新文献

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Radiolucent head immobilization during neurointerventional procedures: A pilot study from a single-institution experience. 神经介入手术期间的头部放射固定:一项来自单一机构经验的试点研究。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2025-09-30 DOI: 10.1177/15910199251382673
Nicholas G Lam, Je Y Sone, William J Ankenbrandt, Matthew T Walker, William J Ares
{"title":"Radiolucent head immobilization during neurointerventional procedures: A pilot study from a single-institution experience.","authors":"Nicholas G Lam, Je Y Sone, William J Ankenbrandt, Matthew T Walker, William J Ares","doi":"10.1177/15910199251382673","DOIUrl":"10.1177/15910199251382673","url":null,"abstract":"<p><p>BackgroundRadiolucent head immobilization (RHI) devices have recently been introduced to the neurovascular space for the purpose of procedural efficiency and safety. However, limited data exists to support its efficacy. In this study, we assessed the potential benefits of RHI. We hypothesized that RHI use is associated with improved procedural efficiency without loss of angiographic image quality or increase in radiation exposure.MethodsA single-institution single-physician retrospective cohort study of patients who underwent cerebral digital subtraction angiography (DSA) or middle meningeal artery embolization (MMAE) under conscious sedation over a 1-year period was conducted. Comparative analyses of fluoroscopy time, image quality, and radiation dosage were performed.ResultsSignificantly shorter fluoroscopy times were observed for patients with RHI undergoing DSA (<i>p</i> < 0.05) and bilateral MMAE (<i>p</i> < 0.05). There was no significant difference in fluoroscopy time for patients undergoing a unilateral MMAE. No difference was found in total radiation dose between patients with RHI compared to patients without RHI. A blinded image quality comparison found no differences in image quality or presence of artifact upon review of DSA images.ConclusionUse of RHI devices was associated with significantly lower fluoroscopy times for DSA and bilateral MMAE without sacrificing image quality. RHI may prove beneficial for decreasing procedural times, particularly during longer, conscious sedation procedures.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"15910199251382673"},"PeriodicalIF":2.1,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12484046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety outcomes in endovascular treatment versus best medical management for basilar artery occlusion acute ischemic stroke: A systematic review and meta-analysis of randomized trials. 血管内治疗与最佳医疗管理对基底动脉闭塞急性缺血性卒中的安全性结果:随机试验的系统回顾和荟萃分析
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2025-09-30 DOI: 10.1177/15910199251383070
João Victor Sanders, Luma Maria Tavares de Sousa, Ocílio de Deus, Marion Oliver, Raul G Nogueira, Demetrius Lopes, Krishna Joshi
{"title":"Safety outcomes in endovascular treatment versus best medical management for basilar artery occlusion acute ischemic stroke: A systematic review and meta-analysis of randomized trials.","authors":"João Victor Sanders, Luma Maria Tavares de Sousa, Ocílio de Deus, Marion Oliver, Raul G Nogueira, Demetrius Lopes, Krishna Joshi","doi":"10.1177/15910199251383070","DOIUrl":"10.1177/15910199251383070","url":null,"abstract":"<p><p>BackgroundEndovascular therapy (EVT) improves functional outcomes and reduces mortality in acute ischemic stroke (AIS) due to basilar artery occlusion (BAO). However, data on hemorrhagic complications and nonneurologic adverse events remain limited. We conducted a systematic review and meta-analysis to assess these outcomes in randomized controlled trials (RCTs) comparing EVT versus best medical management (BMM).MethodsWe searched PubMed, Cochrane Library, and Embase in December 2024 for RCTs comparing EVT and BMM (PROSPERO registry CRD42024617681). Outcomes included any parenchymal hematoma (PH), PH type 1 and 2, subarachnoid hemorrhage (SAH), systemic/extracranial hemorrhage, pneumonia, and heart failure. Pooled risk ratios (RR) with 95% confidence intervals (CI) were calculated using a random-effects model.ResultsFour RCTs, 988 patients (556 EVT, 432 BMM), were included. EVT increased the risk of SAH (RR 5.14; 95% CI [1.35-19.56]; I² = 0.0%) and PH type 2 (RR 5.53; 95% CI [1.47-20.84]; I² = 0.0%) compared to BMM. No significant differences were observed for any PH (RR 1.91; 95% CI [0.92-3.97]; I² = 0.0%), PH type 1 (RR 0.71; 95% CI [0.22-2.29]; I² = 3.4%), systemic/extracranial hemorrhage (RR 1.06; 95% CI [0.71-1.60]; I² = 12.2%), pneumonia (RR 1.00; 95% CI [0.83-1.21]; I² = 0.0%), or heart failure (RR 2.00; 95% CI [0.34-11.92]; I² = 55.4%).ConclusionIn patients with BAO AIS, EVT is associated with an increased risk of SAH and PH type 2 compared with BMM. There was no significant difference in any PH, PH type 1, systemic/extracranial hemorrhage, pneumonia, and heart failure between groups.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"15910199251383070"},"PeriodicalIF":2.1,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12484051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Catheter-assisted sealing technique for spontaneous cerebrospinal fluid leaks: A novel neurointerventional treatment of spontaneous cerebrospinal fluid leak beyond cerebrospinal fluid-venous fistula. 自发性脑脊液泄漏的导管辅助封闭技术:脑脊液-静脉瘘以外自发性脑脊液泄漏的一种新的神经介入治疗方法。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2025-09-30 DOI: 10.1177/15910199251376452
Mario Zanaty, Clayton Lawrence Rosinski, Mohamed Elshikh, Jay Kinariwala, Satoshi Yamaguchi, Kathleen Dlouhy, Edgar Samaniego, Pascal Jabbour, Minako Hayakawa, Santiago Ortega-Gutierrez
{"title":"Catheter-assisted sealing technique for spontaneous cerebrospinal fluid leaks: A novel neurointerventional treatment of spontaneous cerebrospinal fluid leak beyond cerebrospinal fluid-venous fistula.","authors":"Mario Zanaty, Clayton Lawrence Rosinski, Mohamed Elshikh, Jay Kinariwala, Satoshi Yamaguchi, Kathleen Dlouhy, Edgar Samaniego, Pascal Jabbour, Minako Hayakawa, Santiago Ortega-Gutierrez","doi":"10.1177/15910199251376452","DOIUrl":"10.1177/15910199251376452","url":null,"abstract":"<p><p>BackgroundSpontaneous intracranial hypotension (SIH) is a severe condition caused by cerebrospinal fluid (CSF) leaks, leading to headaches and neurological impairments. Traditional epidural blood patch treatment is often ineffective, especially in refractory cases without a source leak identified. This study introduces and evaluates the Catheter-Assisted Sealing Technique (CAST), a novel neurointerventional approach for refractory SIH. CAST involves targeted or diffuse delivery of fibrin glue into the epidural space to repair CSF leaks.MethodsA retrospective case series of ten patients with refractory SIH underwent CAST using a fluoroscopy-guided epidural catheter approach. Clinical symptom resolution and follow-up MRI findings were assessed.ResultsNine of 10 patients achieved complete headache resolution and associated symptom relief. One patient experienced significant improvement without complete relief. Follow-up MRI showed resolution of pachymeningeal enhancement in all patients. One patient required repeat procedures for recurrent symptoms. No neurological injury or spinal cord compression occurred, with the only complication being transient femoral nerve palsy due to positioning that resolved within four months.ConclusionCAST is a promising, minimally invasive alternative for refractory SIH. It enables targeted or diffuse fibrin sealant application, providing a seemingly effective leak closure even in cases of occult or multifocal leaks. Early results show high success and safety rates, but larger cohorts and extended follow-up are needed to validate it as a standard treatment.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"15910199251376452"},"PeriodicalIF":2.1,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12484073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Catheter tensile test: An in vitro evaluation for transradial access. 导管张力试验:经桡动脉通路的体外评价。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2025-09-30 DOI: 10.1177/15910199251384074
Daishiro Abe, Jun-Ichi Koyama, Yoshiki Hanaoka, Takuya Nakamura, Yu Nagai, Tetsuyoshi Horiuchi
{"title":"Catheter tensile test: An in vitro evaluation for transradial access.","authors":"Daishiro Abe, Jun-Ichi Koyama, Yoshiki Hanaoka, Takuya Nakamura, Yu Nagai, Tetsuyoshi Horiuchi","doi":"10.1177/15910199251384074","DOIUrl":"10.1177/15910199251384074","url":null,"abstract":"<p><p>PurposeTransradial access (TRA) has been established for neurointervention; however, complications can occur at the radial access site. Radial artery spasm (RAS) is the most common complication of TRA. Under severe RAS conditions, pulling a catheter may occasionally result in radial artery injury and emergency surgery may be required. There have been no reports on the behavior of entrapped catheters/sheaths when pulled under severe RAS conditions. We conducted tensile tests on guide sheaths and balloon guide catheters to observe their damage in vitro and evaluate their potential to cause vascular injury.MethodsSix types of guide sheaths and balloon guide catheters were used in the test. The catheters were fixed to the testing machine and pulled. We observed how the catheter stretched and fractured. Additionally, a stress-strain curve was obtained from each examination to compare the characteristics of the catheters.ResultsCatheters were damaged in various ways. Some catheters were simply lengthened, whereas others were partially or completely torn. In the evaluation of the stress-strain curves, the slopes of the curves were almost equal among the catheters at the beginning of the test; that is, the hardness was almost the same for each catheter. As the strain increased, each exhibited different behavior.ConclusionCatheters can be damaged in various ways by stretching, which can cause vascular injuries. Neurointerventionists should be aware of possible catheter damage and vascular injury when catheters are entrapped.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"15910199251384074"},"PeriodicalIF":2.1,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12484055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145200971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of the NeVa stent-retriever for bail-out mechanical thrombectomy. NeVa支架取物器在机械溶栓术中的应用。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2025-09-29 DOI: 10.1177/15910199251381491
Rory Fairhead, Marco Mancuso-Marcello, Rafee Ahmed, Keng Siang Lee, Christos Nikola, Katherine Parkin, Giovanna Klefti, Levansri Makalanda, Ken Wong, Joe Lansley, Michael Przyszlak, Oliver Spooner, Pervinder Bhogal
{"title":"The use of the NeVa stent-retriever for bail-out mechanical thrombectomy.","authors":"Rory Fairhead, Marco Mancuso-Marcello, Rafee Ahmed, Keng Siang Lee, Christos Nikola, Katherine Parkin, Giovanna Klefti, Levansri Makalanda, Ken Wong, Joe Lansley, Michael Przyszlak, Oliver Spooner, Pervinder Bhogal","doi":"10.1177/15910199251381491","DOIUrl":"10.1177/15910199251381491","url":null,"abstract":"<p><p>IntroductionMechanical thrombectomy (MT) has become the gold-standard treatment for large vessel occlusion (LVO), however, in many cases, clots cannot be removed with the initial device. We assessed the safety and efficacy of the NeVa stent-retriever when used for bailout, in a real-world scenario where a range of initial devices have failed.MethodsWe reviewed our prospectively maintained database to identify all patients treated with the NeVa device after another device had failed to achieve satisfactory recanalisation. We recorded the baseline demographics, NIHSS, pre- and post-MT imaging data including ASPECT score, eTICI scores, complications and 90-day Modified Rankin Score (mRS).Results39 patients were included with median age 70, 67% male. Median NIHSS at presentation was 17, 11 (28%) received IV tPA prior to MT. A single device prior to NeVa was used in 31 (74%) of cases, with 2 devices used in the remaining patients, in total achieving eTICI ≥ 2b rencanalisation in 4/39 patients (10%). After one NeVa pull, 18 of the remaining 35 eTICI < 2b patients (51%) showed improvement to eTICI ≥ 2b, improving to 26/35 (74%) after multiple NeVa pulls when compared to the pre-NeVa angiographic result. Symptomatic intracranial haemorrhage and subarachnoid haemorrhage occurred in 2/39 (5.1%) and 12/39 (31%), respectively. Functional independence (mRS ≤ 2) at 90 days was seen in 8/35 (23%).ConclusionThe NeVa stent-retriever provides a useful adjunctive device in situations where other devices have failed to achieve recanalisation. Early switching to NeVa rather than repeated pulls with an initial device may be beneficial for timely recanalisation.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"15910199251381491"},"PeriodicalIF":2.1,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vertebrobasilar dolichoectasia future aspects: A meta-analysis of clinical features and treatment strategies. 椎基底动脉过宽症的未来:临床特征和治疗策略的荟萃分析。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2025-09-29 DOI: 10.1177/15910199251380385
Nour Shaheen, Santiago Ortega-Gutierrez, Edgar A Samaniego, Panagiotis Mastorakos, Michael Reid Gooch, Pascal Jabbour, Oliver Flouty, Kathleen Dlouhy, Mario Zanaty
{"title":"Vertebrobasilar dolichoectasia future aspects: A meta-analysis of clinical features and treatment strategies.","authors":"Nour Shaheen, Santiago Ortega-Gutierrez, Edgar A Samaniego, Panagiotis Mastorakos, Michael Reid Gooch, Pascal Jabbour, Oliver Flouty, Kathleen Dlouhy, Mario Zanaty","doi":"10.1177/15910199251380385","DOIUrl":"10.1177/15910199251380385","url":null,"abstract":"<p><p>BackgroundDolichoectatic vertebrobasilar fusiform aneurysm (DVBFA) presents a clinical challenge due to its complex anatomical features and associated neurological complications. This meta-analysis evaluates the clinical outcomes of endovascular therapy (EVT), open surgery, and conservative management for DVBFA.MethodsA systematic review of the PubMed, Scopus, and Web of Science databases on July 18, 2024 was conducted to identify studies reporting on radiologically confirmed DVBFAs. Clinical outcomes were assessed using the modified Rankin Scale (mRS) and mortality rates. Meta-regression was performed to identify potential predictors of treatment outcomes.ResultsTen studies with 219 patients were analyzed. Of the cohort, 58.4% underwent EVT, 24.6% received open surgery, and 16.9% were managed conservatively. The overall proportion of patients achieving a good clinical outcome (mRS < 3) was 46.8%, with EVT showing the highest proportion at 59.4%, compared to 32.3% for open surgery and 24.7% for conservative management (<i>p</i> = 0.0145). The overall mortality rate was 25.98%, with EVT having the lowest mortality rate at 10.06%, followed by open surgery at 44.44% and conservative management at 63.30% (<i>p</i> = 0.0004). Pre- versus post-treatment subgroup analyses, however, did not reveal significant differences between treatment approaches in outcomes.ConclusionEVT appears to provide better clinical outcomes for DVBFAs, though mortality rates remain high across all treatment modalities. The absence of significant differences in subgroup analysis suggests the need for further randomized controlled trials of EVT versus conservative management to establish definitive treatment guidelines.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"15910199251380385"},"PeriodicalIF":2.1,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preliminary efficacy analysis of middle meningeal artery embolization using Glubran 2 for chronic subdural hematoma. 脑膜中动脉栓塞治疗慢性硬膜下血肿的初步疗效分析。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2025-09-29 DOI: 10.1177/15910199251380388
Mingyue Huang, Xin Su, Lisong Bian, Liang Xu, Huishen Pang, Zihao Song, Liyong Sun, Hongqi Zhang, Yongjie Ma
{"title":"Preliminary efficacy analysis of middle meningeal artery embolization using Glubran 2 for chronic subdural hematoma.","authors":"Mingyue Huang, Xin Su, Lisong Bian, Liang Xu, Huishen Pang, Zihao Song, Liyong Sun, Hongqi Zhang, Yongjie Ma","doi":"10.1177/15910199251380388","DOIUrl":"10.1177/15910199251380388","url":null,"abstract":"<p><p>ObjectiveTo preliminarily conclude the safety and efficacy of middle meningeal artery embolization (MMAE) with Glubran 2 in treating chronic subdural hematoma (CSDH).MethodsThis retrospective analysis was performed on 40 consecutive CSDH patients who received MMAE with Glubran 2 between 2021 and 2023. The patients were followed up for 3 years post-operationally. Surgical procedures included burr hole drainage (BHD) and MMAE, both of which were performed under local anesthesia. MMAE with Glubran 2 was performed through transfemoral access. Postoperative recurrence was defined as an increase in hematoma volume based on computed tomography (CT) and/or magnetic resonance imaging (MRI) accompanied by clinical symptoms, which require further treatment within 3 years postoperatively.ResultsIn this study, 40 CSDH patients (34 male and six female) with a mean age of 68.2 ± 13.2 years were included. Of these, 38 patients underwent MMAE-assisted BHD. Two patients received MMAE alone. A single-branch embolization was performed on 20 hematomas in 18 patients, and a double-branch on 27 hematomas in 22 patients. At the three-year follow-up, 33 patients were successfully contacted, and 24 patients showed significant improvement or were asymptomatic after treatment. Three patients passed away owing to non-CSDH-related reasons. One patient developed decompensated liver cirrhosis, one experienced Alzheimer's disease, and four patients experiencing deteriorated functions were unclear but non-CSDH related as demonstrated by absorbed hematomas on head CT or MRI during return visits. The median follow-up time was 35 (IQR 27-40) months, and the median mRS score was 0 (IQR 0-0).ConclusionMMAE-assisted BHD with Glubran 2 is feasible, safe, and effective in treating CSDH, with no associated complications.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"15910199251380388"},"PeriodicalIF":2.1,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479451/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of safety, efficacy, and risk factors for poor clinical prognosis of dual antiplatelet therapy after stent-assisted coil embolization for intracranial ruptured aneurysms. 支架辅助线圈栓塞治疗颅内破裂动脉瘤后双重抗血小板治疗的安全性、有效性及不良临床预后的危险因素分析
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2025-09-26 DOI: 10.1177/15910199251375526
Simin Wang, Tongyu Zhang, Jiewen Geng, Jingwei Li, Sishi Xiang, Peng Hu, Chuan He, Hongqi Zhang
{"title":"Analysis of safety, efficacy, and risk factors for poor clinical prognosis of dual antiplatelet therapy after stent-assisted coil embolization for intracranial ruptured aneurysms.","authors":"Simin Wang, Tongyu Zhang, Jiewen Geng, Jingwei Li, Sishi Xiang, Peng Hu, Chuan He, Hongqi Zhang","doi":"10.1177/15910199251375526","DOIUrl":"10.1177/15910199251375526","url":null,"abstract":"<p><p>BackgroundDual antiplatelet therapy (DAPT) following stent-assisted coil (SAC) embolization increases the risk of ischemic and hemorrhagic complications. To evaluate the safety and efficacy of DAPT in treating acute ruptured aneurysms after SAC and analyze risk factors for poor clinical prognosis.MethodsWe retrospectively analyzed data from patients with aneurysmal subarachnoid hemorrhage (aSAH) between 1 May 2017 and 31 December 2021. Patients were divided into the SAC group and the non-SAC group (NSC). The SAC group received DAPT. We also compared modified Rankin Scale scores and the incidence of bleeding and ischemic complications. Additionally, we analyzed risk factors affecting clinical prognosis.ResultsA total of 2612 patients were included in the analysis: 1011 in the SAC group and 1601 in the NSC group. During hospitalization, there was no significant difference in bleeding and ischemic complications between the groups. Similarly, there was no statistically significant difference in clinical prognosis between the SAC and NSC groups at discharge and six months after discharge. Multivariate analysis indicated age, previous cerebral hemorrhage, posterior circulation aneurysm, multiple aneurysms, modified Fisher scale 3-4, and Glasgow Coma Scale (GCS) scores of 3-8 and 9-12 as risk factors for poor clinical prognosis after SAC.ConclusionsDAPT after SAC for intracranial ruptured aneurysms was found to be safe and effective. Age, previous cerebral hemorrhage, posterior circulation aneurysm, multiple aneurysms, modified Fisher scale 3-4, and GCS scores of 3-12 were identified as risk factors for poor prognosis.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"15910199251375526"},"PeriodicalIF":2.1,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12474573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145179847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reconsidering dimethyl sulfoxide in endovascular embolization: A potential toxic-dependent contributor to hydrocephalus? 重新考虑二甲亚砜在血管内栓塞:一个潜在的毒性依赖因素脑积水?
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2025-09-26 DOI: 10.1177/15910199251380379
Leandro Castaneyra-Ruiz, Brian W Hanak, Sora Sato, Michael Le, Michael Muhonen
{"title":"Reconsidering dimethyl sulfoxide in endovascular embolization: A potential toxic-dependent contributor to hydrocephalus?","authors":"Leandro Castaneyra-Ruiz, Brian W Hanak, Sora Sato, Michael Le, Michael Muhonen","doi":"10.1177/15910199251380379","DOIUrl":"10.1177/15910199251380379","url":null,"abstract":"<p><p>Dimethyl sulfoxide (DMSO) is widely used as a solvent in endovascular embolization procedures, yet its potential neurotoxic effects remain underexplored. In this correspondence, we highlight emerging evidence suggesting that DMSO exposure may contribute to the development of hydrocephalus through mechanisms involving ependymal damage and astrocyte apoptosis. Drawing on recent experimental findings, we propose that DMSO-induced neuroinflammation may play a role in post-embolization complications. We urge the research community to consider hydrocephalus as a possible, though unproven, outcome of DMSO exposure and to include it in long-term safety assessments of embolic agents.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"15910199251380379"},"PeriodicalIF":2.1,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12474570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145179805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Middle meningeal artery embolization as an alternative strategy for symptomatic CSF hypovolemia-related chronic subdural hematoma: A case series. 脑膜中动脉栓塞作为症状性脑脊液低血容量相关慢性硬膜下血肿的替代策略:一个病例系列。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2025-09-25 DOI: 10.1177/15910199251380383
Kun-Ting Hong, Mun-Chun Yeap, Chun-Ting Chen, Ching-Chang Chen
{"title":"Middle meningeal artery embolization as an alternative strategy for symptomatic CSF hypovolemia-related chronic subdural hematoma: A case series.","authors":"Kun-Ting Hong, Mun-Chun Yeap, Chun-Ting Chen, Ching-Chang Chen","doi":"10.1177/15910199251380383","DOIUrl":"10.1177/15910199251380383","url":null,"abstract":"<p><p>BackgroundChronic subdural hematoma (CSDH) secondary to cerebrospinal fluid (CSF) hypovolemia-most commonly from ventriculoperitoneal (VP) shunt overdrainage or spontaneous intracranial hypotension (SIH)-presents unique therapeutic challenges. In these cases, standard surgical evacuation may be contraindicated if intracranial pressure is not corrected, increasing the risk of complications. While middle meningeal artery embolization (MMAE) has emerged as a treatment option for refractory CSDH, its role in CSF-hypovolemia associated CSDH remains underexplored.MethodsThis retrospective study included seven patients with radiographically confirmed, symptomatic CSDH due to CSF hypovolemia. Etiologies included VP shunt overdrainage (n = 6) and SIH (n = 1). Prior to MMAE, all patients underwent definitive treatment of the underlying cause-either shunt adjustment or ligation, or targeted epidural blood patch. Embolization was performed using 250 μm microspheres via the middle meningeal artery. Patients were followed clinically and with serial CT imaging.ResultsAll patients demonstrated neurological improvement within several days following embolization. Hematoma thickness progressively decreased over a period of 2 to 6 months, with complete or near-complete resolution in all cases. No patients experienced recurrence or required surgical evacuation. There were no procedural complications.ConclusionMMAE, when performed after correction of the underlying CSF hypovolemia, appears to be a safe and effective therapeutic option for CSDH. This approach may serve as an intermediate strategy between conservative treatment and surgical evacuation, particularly in patients at elevated risk due to underlying CSF hypovolemia.</p>","PeriodicalId":49174,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"15910199251380383"},"PeriodicalIF":2.1,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12463913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145151592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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